The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.
Electrical Stimulation: A Novel Tool for Tissue Engineering
Abstract
New advances in tissue engineering are being made through the application of different types of electrical stimuli to influence cell proliferation and differentiation. Developments made in the last decade have allowed us to improve the structure and functionality of tissue-engineered products through the use of growth factors, hormones, drugs, physical stimuli, bioreactor use, and two-dimensional (2-D) and three-dimensional (3-D) artificial extracellular matrices (with various material properties and topography). Another potential type of stimulus is electricity, which is important in the physiology and development of the majority of all human tissues. Despite its great potential, its role in tissue regeneration and its ability to influence cell migration, orientation, proliferation, and differentiation has rarely been considered in tissue engineering. This review highlights the importance of endogenous electrical stimulation, gathering the current knowledge on its natural occurrence and role in vivo , discussing the novel methods of delivering this stimulus and examining its cellular and tissue level effects, while evaluating how the technique could benefit the tissue engineering discipline in the future.
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Cites
Electrical stimulation of excitable tissue: design of efficacious and safe protocols
Merrill, D. R., Bikson, M., & Jefferys, J. G. R. (2005) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2004.10.020 · Cited by 2,078
Controlling Cell Behavior Electrically: Current Views and Future Potential
McCaig, C. D., Rajnicek, A. M., Song, B., & Zhao, M. (2005) · Physiological Reviews · doi:10.1152/physrev.00020.2004 · Cited by 1,096
Stimulation of neurite outgrowth using an electrically conducting polymer
Schmidt, C. E., Shastri, V. R., Vacanti, J. P., & Langer, R. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.17.8948 · Cited by 1,071
Radisic, M., Park, H., Shing, H., Consi, T., Schoen, F. J., Langer, R., Freed, L. E., & Vunjak-Novakovic, G. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407817101 · Cited by 910
Electrical fields in wound healing—An overriding signal that directs cell migration
Zhao, M. (2009) · Seminars in Cell & Developmental Biology · doi:10.1016/j.semcdb.2008.12.009 · Cited by 714
Deyo, R. A., Walsh, N. E., Martin, D. C., Schoenfeld, L. S., & Ramamurthy, S. (1990) · New England Journal of Medicine · doi:10.1056/nejm199006073222303 · Cited by 532
Zhao, M., Bai, H., Wang, E., Forrester, J. V., & McCaig, C. D. (2004) · Journal of Cell Science · doi:10.1242/jcs.00868 · Cited by 437
Electromagnetic effects—From cell biology to medicine
Funk, R. H. W., Monsees, T., & Özkucur, N. (2009) · Progress in Histochemistry and Cytochemistry · doi:10.1016/j.proghi.2008.07.001 · Cited by 423
A Role for Endogenous Electric Fields in Wound Healing
Nuccitelli, R. (2003) · Current Topics in Developmental Biology · doi:10.1016/s0070-2153(03)58001-2 · Cited by 390
Cellular mechanisms of direct-current electric field effects: galvanotaxis and metastatic disease
Mycielska, M. E., & Djamgoz, M. B. A. (2004) · Journal of Cell Science · doi:10.1242/jcs.01125 · Cited by 375
Cited by
Han, L., Lu, X., Wang, M., Gan, D., Deng, W., Wang, K., Fang, L., Liu, K., Chan, C. W., Tang, Y., et al. (2017) · Small · doi:10.1002/smll.201601916 · Cited by 699
Liu, Z., Wan, X., Wang, Z. L., & Li, L. (2021) · Advanced Materials · doi:10.1002/adma.202007429 · Cited by 478
Electrical stimulation as a novel tool for regulating cell behavior in tissue engineering
Chen, C., Bai, X., Ding, Y., & Lee, I.-S. (2019) · Biomaterials Research · doi:10.1186/s40824-019-0176-8 · Cited by 444
Piezoelectric materials as stimulatory biomedical materials and scaffolds for bone repair
Tandon, B., Blaker, J. J., & Cartmell, S. H. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.04.026 · Cited by 420
Self-citationThrivikraman, G., Boda, S. K., & Basu, B. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2017.10.003 · Cited by 384
Metadata
- Authors
- Balint, R., Cassidy, N. J., & Cartmell, S. H.
- Venue
- Tissue Engineering Part B: Reviews
- Publisher
- SAGE Publications
- Published
- 2012-10-08
- Volume
- 19
- Issue
- 1
- Pages
- 48-57
- ISSN
- 1937-3368 (ISSN-L)
- 1937-3376
- OpenAlex
- W2087776156
- Cited by
- 405
- References
- 74
- FWCI
- 10.82
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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