The DOI matches its Crossref record; 97 of the 97 references it cites were found in a registry or an index.
The Evolution of Polystyrene as a Cell Culture Material
Open accessAbstract
Polystyrene (PS) has brought in vitro cell culture from its humble beginnings to the modern era, propelling dozens of research fields along the way. This review discusses the development of the material, fabrication, and treatment approaches to create the culture material. However, native PS surfaces poorly facilitate cell adhesion and growth in vitro . To overcome this, liquid surface deposition, energetic plasma activation, and emerging functionalization methods transform the surface chemistry. This review seeks to highlight the many potential applications of the first widely accepted polymer growth surface. Although the majority of in vitro research occurs on two-dimensional surfaces, the importance of three-dimensional (3D) culture models cannot be overlooked. The methods to transition PS to specialized 3D culture surfaces are also reviewed. Specifically, casting, electrospinning, 3D printing, and microcarrier approaches to shift PS to a 3D culture surface are highlighted. The breadth of applications of the material makes it impossible to highlight every use, but the aim remains to demonstrate the versatility and potential as both a general and custom cell culture surface. The review concludes with emerging scaffolding approaches and, based on the findings, presents our insights on the future steps for PS as a tissue culture platform.
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Cited by
Joseph, B., James, J., Kalarikkal, N., & Thomas, S. (2021) · Advanced Industrial and Engineering Polymer Research · doi:10.1016/j.aiepr.2021.06.003 · Cited by 195
Microfluidic high-throughput 3D cell culture
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Kaniuk, Ł., Krysiak, Z. J., Metwally, S., & Stachewicz, U. (2020) · Materials Science and Engineering: C · doi:10.1016/j.msec.2020.110668 · Cited by 63
Vasconcelos, E. V., da Luz, F. B., da Paz, S. P. A., dos Reis, M. A. L., da Silva, A. C. R., Passos, M. F., Barboza, C. A. G., Monteiro, S. N., & Candido, V. S. (2023) · Journal of Materials Research and Technology · doi:10.1016/j.jmrt.2023.02.171 · Cited by 35
Testing Lab-on-a-Chip Technology for Culturing Human Melanoma Cells under Simulated Microgravity
Przystupski, D., Górska, A., Michel, O., Podwin, A., Śniadek, P., Łapczyński, R., Saczko, J., & Kulbacka, J. (2021) · Cancers · doi:10.3390/cancers13030402 · Cited by 29
Metadata
- Authors
- Lerman, M. J., Lembong, J., Muramoto, S., Gillen, G., & Fisher, J. P.
- Venue
- Tissue Engineering Part B: Reviews
- Publisher
- SAGE Publications
- Published
- 2018-10
- Volume
- 24
- Issue
- 5
- Pages
- 359-372
- ISSN
- 1937-3368 (ISSN-L)
- 1937-3376
- OpenAlex
- W2797304017
- Cited by
- 258
- References
- 97
- FWCI
- 7.82
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Lerman, M. J., Lembong, J., Muramoto, S., Gillen, G., & Fisher, J. P. (2018). The Evolution of Polystyrene as a Cell Culture Material. Tissue Engineering Part B: Reviews. https://doi.org/10.1089/ten.teb.2018.0056
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
