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Management of Graves' Ophthalmopathy: Reality and Perspectives

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Thyrotropin Receptor Autoantibodies Are Independent Risk Factors for Graves’ Ophthalmopathy and Help to Predict Severity and Outcome of the Disease

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Smoking and Risk of Graves' Disease

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Epidemiology and Prevention of Graves' Ophthalmopathy

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Randomized, Single Blind Trial of IntravenousversusOral Steroid Monotherapy in Graves’ Orbitopathy

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Prednisone and Cyclosporine in the Treatment of Severe Graves' Ophthalmopathy

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Randomised double-blind trial of prednisone versus radiotherapy in Graves' ophthalmopathy

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Development of a disease specific quality of life questionnaire for patients with Graves' ophthalmopathy: the GO-QOL

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Use of Corticosteroids to Prevent Progression of Graves' Ophthalmopathy after Radioiodine Therapy for Hyperthyroidism

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Smoking and thyroid disorders--a meta-analysis

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Comparison of the Effectiveness and Tolerability of Intravenous or Oral Glucocorticoids Associated with Orbital Radiotherapy in the Management of Severe Graves' Ophthalmopathy: Results of a Prospective, Single-Blind, Randomized Study

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Clinical assessment of patients with Graves’ orbitopathy: the European Group on Graves’ Orbitopathy recommendations to generalists, specialists and clinical researchers

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Cigarette Smoking and Treatment Outcomes in Graves Ophthalmopathy

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Radiotherapy for Graves' orbitopathy: randomised placebo-controlled study

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Orbital Cobalt Irradiation Combined with Systemic Corticosteroids for Graves' Ophthalmopathy: Comparison with Systemic Corticosteroids Alone*

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Treatment of Graves’ disease and associated ophthalmopathy with the anti-CD20 monoclonal antibody rituximab: an open study

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A prospective, randomized, double-blind, placebo-controlled study of orbital radiotherapy for Graves’ ophthalmopathy

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Management of Graves' Ophthalmopathy: Reality and Perspectives

Bartalena, L. (2000) · Endocrine Reviews · doi:10.1210/er.21.2.168 · Cited by 257 · see citing works

Effect of Abnormal Thyroid Function on the Severity of Graves' Ophthalmopathy

Prummel, M. F. (1990) · Archives of Internal Medicine · doi:10.1001/archinte.1990.00390170124027 · Cited by 238 · see citing works

<b>Smoking and endocrine ophthalmopathy: impact of smoking severity and current<i> vs </i>lifetime cigarette consumption</b>

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A Randomized Controlled Trial of Orbital Radiotherapy Versus Sham Irradiation in Patients with Mild Graves’ Ophthalmopathy

Prummel, M. F., Terwee, C. B., Gerding, M. N., Baldeschi, L., Mourits, M. P., Blank, L. E. C. M., Dekker, F. W., & Wiersinga, W. M. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-030809 · Cited by 227 · see citing works

Cigarette smoking and thyroid eye disease: a systematic review

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Surgical or medical decompression as a first‐line treatment of optic neuropathy in Graves’ ophthalmopathy? A randomized controlled trial

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Impact of smoking on the response to treatment of thyroid associated ophthalmopathy

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Controversies in the clinical evaluation of active thyroid‐associated orbitopathy: use of a detailed protocol with comparative photographs for objective assessment

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Ciclosporin and prednisone v. prednisone in treatment of Graves' ophthalmopathy: a controlled, randomized and prospective study

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More on smoking habits and Graves’ ophthalmopathy

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The effect of etanercept on Graves' ophthalmopathy: a pilot study

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Psychosocial morbidity of Graves’ orbitopathy

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Does early administration of thyroxine reduce the development of Graves' ophthalmopathy after radioiodine treatment?

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Acute and Severe Liver Damage Associated with Intravenous Glucocorticoid Pulse Therapy in Patients with Graves' Ophthalmopathy

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Association between Graves' ophthalmopathy and smoking

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Orbital irradiation for Graves' ophthalmopathy

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A Prospective Study of the Effects of Radioiodine Therapy for Hyperthyroidism in Patients with Minimally Active Graves’ Ophthalmopathy

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Orbital radiotherapy combined with high dose systemic glucocorticoids for Graves’ ophthalmopathy is more effective than radiotherapy alone: results of a prospective randomized study

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Is endocrine ophthalmopathy related to smoking?

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Low- Versus High-Dose Radiotherapy for Graves’ Ophthalmopathy: A Randomized, Single Blind Trial

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Determinants of Liver Damage Associated with Intravenous Methylprednisolone Pulse Therapy in Graves' Ophthalmopathy

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Treatment of upper eyelid retraction associated with thyroid eye disease with subconjunctival botulinum toxin injection1 1The authors have no proprietary or commercial interests in any of the substances used.

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Effects of Total Thyroid Ablation Versus Near-Total Thyroidectomy Alone on Mild to Moderate Graves’ Orbitopathy Treated with Intravenous Glucocorticoids

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Long-Term Safety of Orbital Radiotherapy for Graves’ Ophthalmopathy

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The Association of Cigarette Smoking with Clinical Subtypes of Ophthalmic Gravesʼ Disease

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Childhood Graves’ ophthalmopathy: results of a European questionnaire study

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Relationship between cigarette smoking and Graves’ ophthalmopathy

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The course of Graves' ophthalmopathy is not influenced by near total thyroidectomy: a case‐control study

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Randomized trial of intravenous immunoglobulins versus prednisolone in Graves' ophthalmopathy

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Fatal Liver Failure After High-Dose Glucocorticoid Pulse Therapy in a Patient with Severe Thyroid Eye Disease

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Smoking and risk of Graves' disease

Prummel, M. F. (1993) · JAMA · doi:10.1001/jama.269.4.479 · Cited by 100 · see citing works

Synergism between diabetic and radiation retinopathy: case report and review.

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The Removal of the Deep Lateral Wall in Orbital Decompression: Its Contribution to Exophthalmos Reduction and Influence on Consecutive Diplopia

Baldeschi, L., Macandie, K., Hintschich, C. R., Wakelkamp, I. M. M. J., Prummel, M. F., & Wiersinga, W. M. (2005) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2005.04.023 · Cited by 94 · see citing works

High-dose intravenous corticosteroid therapy for Graves’ ophthalmopathy

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Management of Graves' ophthalmopathy

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High dose intravenous methylprednisolone pulse therapy versus oral prednisone for thyroid‐associated ophthalmopathy

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Long-term results of irradiation for patients with progressive GRAVES’ ophthalmopathy

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Effects of Graves’ ophthalmopathy on quality of life

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Azathioprine in the treatment of thyroid-associated ophthalmopathy

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Relationship Between Graves' Ophthalmopathy and Type of Treatment of Graves' Hyperthyroidism

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Double-Blind, Placebo-Controlled Trial of Octreotide Long-Acting Repeatable (LAR) in Thyroid-Associated Ophthalmopathy

Dickinson, A. J., Vaidya, B., Miller, M. A., Coulthard, A., Perros, P., Baister, E. R., Andrews, C. D., Hesse, L., Heverhagen, J. T., Heufelder, A. E., et al. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0697 · Cited by 89 · see citing works

The Effect of Somatostatin versus Corticosteroid in the Treatment of Graves' Ophthalmopathy

Kung, A. W. C., Michon, J., Tai, K. S., & Chan, F. L. (1996) · Thyroid · doi:10.1089/thy.1996.6.381 · Cited by 88 · see citing works

Smoking and autoimmune thyroid disease: the plot thickens

Krassas, G. E., & Wiersinga, W. M. (2006) · European Journal of Endocrinology · doi:10.1530/eje.1.02157 · Cited by 83 · see citing works

Graves' ophthalmopathy: a preventable disease?

Bartalena, L., Marcocci, C., & Pinchera, A. (2002) · European Journal of Endocrinology · doi:10.1530/eje.0.1460457 · Cited by 83 · see citing works

Graves' Disease with Moderate–Severe Endocrine Ophthalmopathy–Long Term Results of a Prospective, Randomized Study of Total or Subtotal Thyroid Resection

Järhult, J., Rudberg, C., Larsson, E., Selvander, H., Sjövall, K., Winsa, B., Rastad, J., Karlsson, F. A., & TEO Study Group (2005) · Thyroid · doi:10.1089/thy.2005.15.1157 · Cited by 82 · see citing works

Octreotide (Long-Acting Release Formulation) Treatment in Patients with Graves’ Orbitopathy: Clinical Results of a Four-Month, Randomized, Placebo-Controlled, Double-Blind Study

Wémeau, J.-L., Caron, P. J., Beckers, A. M., Rohmer, V., Orgiazzi, J., Borson‐Chazot, F., Calzada-Nocaudie, M., Perimenis, P., Bisot-Locard, S., Bourdeix, I., et al. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1334 · Cited by 82 · see citing works

Reactivation of Graves’ Orbitopathy after Rehabilitative Orbital Decompression

Baldeschi, L., Lupetti, A., Vu, P., Wakelkamp, I. M. M. J., Prummel, M. F., & Wiersinga, W. M. (2007) · Ophthalmology · doi:10.1016/j.ophtha.2006.10.036 · Cited by 78 · see citing works

Graves' disease, endocrine ophthalmopathy and smoking

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High-dose intravenous immunoglobulin treatment in Graves' ophthalmopathy

Antonelli, A., Saracino, A., ALBERTI, B., Canapicchi, R., Cartei, F., Lepri, A., Laddaga, M., & Baschieri, L. (1992) · European Journal of Endocrinology · doi:10.1530/acta.0.1260013 · Cited by 75 · see citing works

Clinical features and treatment of late enophthalmos after orbital decompression

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A questionnaire survey on the management of Graves’ orbitopathy in Europe

_, _., Perros, P., Baldeschi, L., Boboridis, K. G., Dickinson, A. J., Hullo, A., Kahaly, G. J., Kendall-Taylor, P., Krassas, G. E., Lane, C., et al. (2006) · European Journal of Endocrinology · doi:10.1530/eje.1.02201 · Cited by 74 · see citing works

Graves’ ophthalmopathy: a rational approach to treatment

Wiersinga, W. M., & Prummel, M. F. (2002) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(02)00622-7 · Cited by 73 · see citing works

Pathogenesis of Graves’ Ophthalmopathy—Current Understanding

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Optic neuropathy of graves disease: results of transantral orbital decompression and long-term follow-up in 215 patients

Soares-Welch, C. V., Fatourechi, V., Bartley, G. B., Beatty, C. W., Gorman, C. A., Bahn, R. S., Bergstralh, E. J., Schleck, C. D., & Garrity, J. A. (2003) · American Journal of Ophthalmology · doi:10.1016/s0002-9394(03)00233-2 · Cited by 72 · see citing works

Combined orbital irradiation and systemic steroids compared with systemic steroids alone in the management of moderate-to-severe Graves' ophthalmopathy: a preliminary study.

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Randomized, Double-Blind, Placebo-Controlled Trial of Long-Acting Release Octreotide for Treatment of Graves’ Ophthalmopathy

Stan, M. N., Garrity, J. A., Bradley, E. A., Woog, J. J., Bahn, M. M., BRENNAN, M. D., Bryant, S. C., Achenbach, S. J., & Bahn, R. S. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-1105 · Cited by 65 · see citing works

Extraocular muscle surgery for Graves' ophthalmopathy: does prior treatment influence surgical outcome?

Mourits, M. P., Koornneef, L., Mourik-Noordenbos, A. M. V., van der Meulen-Schot, H. M., Prummel, M. F., Wiersinga, W. M., & Berghout, A. (1990) · British Journal of Ophthalmology · doi:10.1136/bjo.74.8.481 · Cited by 64 · see citing works

Low- Versus High-Dose Radiotherapy for Graves' Ophthalmopathy: A Randomized, Single Blind Trial

Kahaly, G. J. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.85.1.102 · Cited by 60 · see citing works

Early Response to Intravenous Glucocorticoids for Severe Thyroid-Associated Ophthalmopathy Predicts Treatment Outcome

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Glucocorticoid inhibition of stimulus-evoked adrenocorticotrophin release caused by suppression of intracellular calcium signals

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In vitro effects of ketoconazole on corticotrope cell morphology and ACTH secretion of two pituitary adenomas removed from patients with Nelson's syndrome

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