Myosin Va bound to phagosomes binds to F-actin and delays microtubule-dependent motility

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302 · see citing works

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

LAEMMLI, U. K. (1970) · Nature · doi:10.1038/227680a0 · Cited by 249,961 · see citing works

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Towbin, H., Staehelin, T., & Gordon, J. (1979) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.76.9.4350 · Cited by 51,421 · see citing works

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

Raza, H., John, A., & Nemmar, A. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350087 · Cited by 47,311 · see citing works

The Regulation of Rabbit Skeletal Muscle Contraction

Spudich, J. A., & Watt, S. (1971) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)62016-2 · Cited by 4,496 · see citing works

Mechanisms of phagocytosis in macrophages

Aderem, A., & Underhill, D. M. (1999) · Annual Review of Immunology · doi:10.1146/annurev.immunol.17.1.593 · Cited by 2,854 · see citing works

Myosin-V is a processive actin-based motor

Mehta, A. D., Rock, R. S., Rief, M., Spudich, J. A., Mooseker, M. S., & Cheney, R. E. (1999) · Nature · doi:10.1038/23072 · Cited by 781 · see citing works

Phagocytosis and the actin cytoskeleton

May, R. C., & Machesky, L. M. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.6.1061 · Cited by 715 · see citing works

The Phagosome Proteome

Garin, J., Diez, R., Kieffer‐Jaquinod, S., Dermine, J.-F., Duclos, S., Gagnon, É., Sadoul, R., Rondeau, C., & Desjardins, M. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.152.1.165 · Cited by 686 · see citing works

Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus

Desjardins, M., Huber, L., Parton, R., & Griffiths, G. (1994) · The Journal of Cell Biology · doi:10.1083/jcb.124.5.677 · Cited by 673 · see citing works

Unconventional Myosins in Cell Movement, Membrane Traffic, and Signal Transduction

Mermall, V., Post, P. L., & Mooseker, M. S. (1998) · Science · doi:10.1126/science.279.5350.527 · Cited by 654 · see citing works

Brain myosin-V is a two-headed unconventional myosin with motor activity

Cheney, R. E., O'Shea, M. K., Heuser, J. E., Coelho, M. V., Wolenski, J. S., Espreáfico, E. M., Forscher, P., Larson, R. E., & Mooseker, M. S. (1993) · Cell · doi:10.1016/s0092-8674(05)80080-7 · Cited by 445 · see citing works

Gliding movement of and bidirectional transport along single native microtubules from squid axoplasm: evidence for an active role of microtubules in cytoplasmic transport.

ALLEN, R. D., Weiss, D. G., Hayden, J. H., Brown, D. T., Fujiwake, H., & Simpson, M. (1985) · The Journal of Cell Biology · doi:10.1083/jcb.100.5.1736 · Cited by 440 · see citing works

Visualization of Melanosome Dynamics within Wild-Type and Dilute Melanocytes Suggests a Paradigm for Myosin V Function In Vivo

Wu, X., Bowers, B., Rao, K., Wei, Q., & Hammer, J. A. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.143.7.1899 · Cited by 419 · see citing works

Myosin-V stepping kinetics: A molecular model for processivity

Rief, M., Rock, R. S., Mehta, A. D., Mooseker, M. S., Cheney, R. E., & Spudich, J. A. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.17.9482 · Cited by 402 · see citing works

Actin-dependent organelle movement in squid axoplasm

Kuznetsov, S. A., Langford, G. M., & Weiss, D. G. (1992) · Nature · doi:10.1038/356722a0 · Cited by 367 · see citing works

Function of Rho family proteins in actin dynamics during phagocytosis and engulfment

Chimini, G., & Chavrier, P. (2000) · Nature Cell Biology · doi:10.1038/35036454 · Cited by 329 · see citing works

Two-headed binding of a processive myosin to F-actin

Walker, M., Burgess, S. A., Sellers, J. R., Wang, F., Hammer, J. A., Trinick, J. A., & Knight, P. J. (2000) · Nature · doi:10.1038/35015592 · Cited by 302 · see citing works

INHIBITION OF PHAGOCYTOSIS AND PLASMA MEMBRANE MOBILITY OF THE CULTIVATED MACROPHAGE BY CYTOCHALASIN B

Axline, S. G., & REAVEN, E. P. (1974) · The Journal of Cell Biology · doi:10.1083/jcb.62.3.647 · Cited by 291 · see citing works

A contractile activity that closes phagosomes in macrophages

Swanson, J. A., Johnson, M. T., Beningo, K. A., Post, P. L., Mooseker, M. S., & Araki, N. (1999) · Journal of Cell Science · doi:10.1242/jcs.112.3.307 · Cited by 282 · see citing works

Class V myosins

Reck‐Peterson, S. L., Provance, D. W., Mooseker, M. S., & Mercer, J. A. (2000) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(00)00007-0 · Cited by 281 · see citing works

Molecular characterization of phagosomes.

Desjardins, M., Celis, J. E., Gerrit van, M. E. E. R., Dieplinger, H., Jahraus, A., Griffiths, G. W., & Huber, L. A. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)31620-x · Cited by 279 · see citing works

Polarized Intracellular Particle Transport: Saltatory Movements and Cytoplasmic Streaming

Rebhun, L. I. (1972) · International review of cytology · doi:10.1016/s0074-7696(08)60339-3 · Cited by 272 · see citing works

Immunocytochemical characterization of the endocytic and phagolysosomal compartments in peritoneal macrophages

Rabinowitz, S., Horstmann, H., Gordon, S., & Griffiths, G. (1992) · The Journal of Cell Biology · doi:10.1083/jcb.116.1.95 · Cited by 271 · see citing works

Myosin cooperates with microtubule motors during organelle transport in melanophores

Rogers, S. L., & Gelfand, V. I. (1998) · Current Biology · doi:10.1016/s0960-9822(98)70063-6 · Cited by 245 · see citing works

Myosin V associates with melanosomes in mouse melanocytes: evidence that myosin V is an organelle motor

Wu, X., Bowers, B., Wei, Q., Kocher, B., & Hammer, J. A. (1997) · Journal of Cell Science · doi:10.1242/jcs.110.7.847 · Cited by 230 · see citing works

Molecular Requirements for Bi-directional Movement of Phagosomes Along Microtubules

Blocker, A., Severin, F. F., Burkhardt, J. K., Bingham, J. B., Yu, H., Olivo‐Marín, J., Schroer, T. A., Hyman, A. A., & Griffiths, G. W. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.137.1.113 · Cited by 229 · see citing works

Lysosomal Enzyme Trafficking between Phagosomes, Endosomes, and Lysosomes in J774 Macrophages

Claus, V., Jahraus, A., Tjelle, T. E., Berg, T., Kirschke, H., Faulstich, H., & Griffiths, G. W. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.16.9842 · Cited by 205 · see citing works

Identification of replication factor C from Saccharomyces cerevisiae: a component of the leading-strand DNA replication complex.

Fien, K., & Stillman, B. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.1.155 · Cited by 204 · see citing works

Transport of ER vesicles on actin filaments in neurons by myosin V

Tabb, J. S., Molyneaux, B. J., Cohen, D. L., Kuznetsov, S. A., & Langford, G. M. (1998) · Journal of Cell Science · doi:10.1242/jcs.111.21.3221 · Cited by 203 · see citing works

Involvement of ezrin/moesin in de novo actin assembly on phagosomal membranes

Defacque, H., Egeberg, M., Habermann, A., Diakonova, M., Roy, C., Mangeat, P. H., Voelter, W., Marriott, G., Pfannstiel, J., Faulstich, H., et al. (2000) · The EMBO Journal · doi:10.1093/emboj/19.2.199 · Cited by 174 · see citing works

Structure and function of the cytoskeleton of a Dictyostelium myosin-defective mutant.

Fukui, Y., Lozanne, A. D., & Spudich, J. A. (1990) · The Journal of Cell Biology · doi:10.1083/jcb.110.2.367 · Cited by 171 · see citing works

Interactions between actin, myosin, and an actin-binding protein from rabbit alveolar macrophages. Alveolar macrophage myosin Mg-2+-adenosine triphosphatase requires a cofactor for activation by actin.

Stossel, T. P., & Hartwig, J. H. (1975) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)41236-2 · Cited by 158 · see citing works

Myosin VA Movements in Normal and Dilute-Lethal Axons Provide Support for a Dual Filament Motor Complex

Bridgman, P. C. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.146.5.1045 · Cited by 151 · see citing works

Vesicle-associated brain myosin-V can be activated to catalyze actin-based transport

Evans, L., Lee, A. J., Bridgman, P. C., & Mooseker, M. S. (1998) · Journal of Cell Science · doi:10.1242/jcs.111.14.2055 · Cited by 136 · see citing works

Localization of five annexins in J774 macrophages and on isolated phagosomes

Diakonova, M., Gerke, V., Ernst, J., Liautard, J., Vusse, G. J., & Griffiths, G. W. (1997) · Journal of Cell Science · doi:10.1242/jcs.110.10.1199 · Cited by 132 · see citing works

In Vitro Fusion of Phagosomes with Different Endocytic Organelles from J774 Macrophages

Jahraus, A., Tjelle, T. E., Berg, T., Habermann, A., Storrie, B., Ullrich, O., & Griffiths, G. W. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.46.30379 · Cited by 124 · see citing works

Evidence for retrograde traffic between terminal lysosomes and the prelysosomal/late endosome compartment

Jahraus, A., Storrie, B., Griffiths, G., & Desjardins, M. (1994) · Journal of Cell Science · doi:10.1242/jcs.107.1.145 · Cited by 119 · see citing works

ATP-dependent Membrane Assembly of F-Actin Facilitates Membrane Fusion

Jahraus, A., Egeberg, M., Hinner, B., Habermann, A., Sackmann, E., Pralle, A., Faulstich, H., Rybin, V., Defacque, H., & Griffiths, G. W. (2001) · Molecular Biology of the Cell · doi:10.1091/mbc.12.1.155 · Cited by 116 · see citing works

Functions of unconventional myosins

Wu, X., Jung, G., & Hammer, J. A. (2000) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(99)00055-1 · Cited by 113 · see citing works

Colocalization of F-actin and talin during Fc receptor-mediated phagocytosis in mouse macrophages.

Greenberg, S., Burridge, K., & Silverstein, S. C. (1990) · The Journal of Experimental Medicine · doi:10.1084/jem.172.6.1853 · Cited by 112 · see citing works

Biochemical and immunological characterization of p190-calmodulin complex from vertebrate brain: a novel calmodulin-binding myosin.

Espíndola, F. S., Espreáfico, E. M., Coelho, M. V., Martins, A. R., Costa, F., Mooseker, M. S., & Larson, R. E. (1992) · The Journal of Cell Biology · doi:10.1083/jcb.118.2.359 · Cited by 112 · see citing works

Transport of phagosomal components to an endosomal compartment.

Pitt, A., Mayorga, L. S., Schwartz, A. L., & Stahl, P. D. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)48468-2 · Cited by 108 · see citing works

Chapter 22 Myosin Purification and Characterization

Pollard, T. D. (1982) · Methods in cell biology · doi:10.1016/s0091-679x(08)60665-2 · Cited by 95 · see citing works

Subcellular Localization of Myosin-V in the B16 Melanoma Cells, a Wild-type Cell Line for thediluteGene

Nascimento, A. A. C., Amaral, R. G., Bizário, J. C. S., Larson, R. E., & Espreáfico, E. M. (1997) · Molecular Biology of the Cell · doi:10.1091/mbc.8.10.1971 · Cited by 90 · see citing works

A role for microtubule dynamics in phagosome movement

Blocker, A., Griffiths, G. W., Olivo‐Marín, J., Hyman, A. A., & Severin, F. F. (1998) · Journal of Cell Science · doi:10.1242/jcs.111.3.303 · Cited by 84 · see citing works

Microtubule-associated protein-dependent binding of phagosomes to microtubules

Blocker, A., Severin, F. F., Habermann, A., Hyman, A. A., Griffiths, G., & Burkhardt, J. K. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.7.3803 · Cited by 81 · see citing works

Myosin V in the brain: mutations lead to neurological defects

Langford, G. M., & Molyneaux, B. J. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00020-4 · Cited by 61 · see citing works

[1] Purification and assay of myosin V

Cheney, R. E. (1998) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(98)98003-x · Cited by 56 · see citing works

Dynamics of the cytoskeleton in Amoeba proteus

Stockem, W., Hoffmann, H.-U., & Gruber, B. (1983) · Cell and Tissue Research · doi:10.1007/bf00222375 · Cited by 46 · see citing works

Transport of phagosomes in mouse peritoneal macrophages

Toyohara, A., & Inaba, K. (1989) · Journal of Cell Science · doi:10.1242/jcs.94.1.143 · Cited by 44 · see citing works

Phagosomal Proteins of Dictyostelium discoideum

REZABEK, B. L., Rodriguez‐Paris, J., Cardelli, J. A., & Chia, C. P. (1997) · Journal of Eukaryotic Microbiology · doi:10.1111/j.1550-7408.1997.tb05668.x · Cited by 35 · see citing works

Towards a new classification of intracellular particle movements based on quantitative analyses

Weiss, D. G., Keller, F., Gulden, J., & Maile, W. (1986) · Cell Motility and the Cytoskeleton · doi:10.1002/cm.970060210 · Cited by 30 · see citing works

Myosin light chain phosphorylation does not increase during yeast phagocytosis by macrophages

de Lanerolle, P., Gorgas, G., Li, X., & Schluns, K. S. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)85276-6 · Cited by 26 · see citing works

Chapter 10 Macrophages: Their Use in Elucidation of the Cytoskeletal Roles of Actin

Hartwig, J. H., & Stossel, T. P. (1982) · Methods in cell biology · doi:10.1016/s0091-679x(08)61426-0 · Cited by 3 · see citing works

[Splenic protein forming a gel with actin].

Гиоева, Ф. К., Vi, G., & Rozenblat, V. A. (1983) · PubMed · Cited by 2 · see citing works

Phagocytosis: Our Current Understanding of a Universal Biological Process

Uribe-Querol, E., & Rosales, C. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01066 · Cited by 651 · see citing works

CELL BIOLOGY OF MYCOBACTERIUM TUBERCULOSIS PHAGOSOME

Vergne, I., Chua, J., Singh, S., & Deretic, V. P. (2004) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.20.010403.114015 · Cited by 440 · see citing works

Dual control of caveolar membrane traffic by microtubules and the actin cytoskeleton

Mundy, D. I., Machleidt, T., Ying, Y., Anderson, R. G. W., & Bloom, G. S. (2002) · Journal of Cell Science · doi:10.1242/jcs.00117 · Cited by 297 · see citing works

Molecular Adaptations Allow Dynein to Generate Large Collective Forces inside Cells

Rai, A. K., Rai, A., Ramaiya, A., Jha, R., & Mallik, R. (2013) · Cell · doi:10.1016/j.cell.2012.11.044 · Cited by 284 · see citing works

Patterns, Receptors, and Signals: Regulation of Phagosome Maturation

Pauwels, A.-M., Trost, M., Beyaert, R., & Hoffmann, E. (2017) · Trends in Immunology · doi:10.1016/j.it.2017.03.006 · Cited by 264 · see citing works

Abnormal phagocytosis by retinal pigmented epithelium that lacks myosin VIIa, the Usher syndrome 1B protein.

Gibbs, D., Kitamoto, J., & Williams, D. S. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1130432100 · Cited by 250 · see citing works

Molecular mechanisms of phagocytic uptake in mammalian cells

Groves, E., Dart, A., Covarelli, V., & Caron, E. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-7578-4 · Cited by 224 · see citing works

Phosphoinositide-3-kinase-independent contractile activities associated with Fcγ-receptor-mediated phagocytosis and macropinocytosis in macrophages

Araki, N., Hatae, T., Furukawa, A., & Swanson, J. A. (2002) · Journal of Cell Science · doi:10.1242/jcs.00235 · Cited by 190 · see citing works

Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors

Hendricks, A. G., Holzbaur, E. L. F., & Goldman, Y. E. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1215462109 · Cited by 179 · see citing works

Myosin Va Transports Dense Core Secretory Vesicles in Pancreatic MIN6 β-Cells

Váradi, A., Tsuboi, T., & Rutter, G. A. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-11-1001 · Cited by 172 · see citing works

Phagocytosis: latex leads the way

Desjardins, M., & Griffiths, G. (2003) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(03)00083-8 · Cited by 159 · see citing works

Disruption of microtubules inhibits cytoplasmic ribonucleoprotein stress granule formation

Ivanov, P. A., Чудинова, Е. М., & Nadezhdina, E. S. (2003) · Experimental Cell Research · doi:10.1016/s0014-4827(03)00290-8 · Cited by 150 · see citing works

The Melanosome as a Model to Study Organelle Motility in Mammals

Barral, D. C., & Seabra, M. C. (2004) · Pigment Cell Research · doi:10.1111/j.1600-0749.2004.00138.x · Cited by 129 · see citing works

Myosin Va facilitates the distribution of secretory granules in the F-actin rich cortex of PC12 cells

Rudolf, R., Kögel, T., Kuznetsov, S. A., Salm, T., Schlicker, O., Hellwig, A., Hammer, J. A., & Gerdes, H. (2003) · Journal of Cell Science · doi:10.1242/jcs.00317 · Cited by 124 · see citing works

Better Together: Current Insights Into Phagosome-Lysosome Fusion

Nguyen, J. A., & Yates, R. M. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.636078 · Cited by 120 · see citing works

Fusion between Phagosomes, Early and Late Endosomes: A Role for Actin in Fusion between Late, but Not Early Endocytic Organelles

Kjeken, R., Egeberg, M., Habermann, A., Kühnel, M., Peyron, P., Floetenmeyer, M., Walther, P., Jahraus, A., Defacque, H., Kuznetsov, S. A., et al. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.e03-05-0334 · Cited by 108 · see citing works

Interaction of the actin cytoskeleton with microtubules regulates secretory organelle movement near the plasma membrane in human endothelial cells

Manneville, J., Etienne‐Manneville, S., Skehel, P., Carter, T. D., Ogden, D., & Ferenczi, M. A. (2003) · Journal of Cell Science · doi:10.1242/jcs.00672 · Cited by 107 · see citing works

Nanoparticle entry into cells; the cell biology weak link

Griffiths, G. W., Grüenberg, J., Marsh, M., Wohlmann, J., Jones, A. T., & Parton, R. G. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114403 · Cited by 99 · see citing works

Motor Number Controls Cargo Switching at Actin-Microtubule Intersections In Vitro

Schroeder, H. W., Mitchell, T. J., Shuman, H., Holzbaur, E. L. F., & Goldman, Y. E. (2010) · Current Biology · doi:10.1016/j.cub.2010.03.024 · Cited by 90 · see citing works

Autonomous phagosomal degradation and antigen presentation in dendritic cells

Hoffmann, E., Kotsias, F., Visentin, G., Bruhns, P., Savina, A., & Amigorena, S. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1203912109 · Cited by 88 · see citing works

Microtubule motors transport phagosomes in the RPE, and lack of KLC1 leads to AMD-like pathogenesis

Jiang, M., Esteve-Rudd, J., Lopes, V. S., Diemer, T., Lillo, C., Rump, A., & Williams, D. S. (2015) · Journal of Cell Biology · doi:10.1083/jcb.201410112 · Cited by 85 · see citing works

Myosin Va and microtubule-based motors are required for fast axonal retrograde transport of tetanus toxin in motor neurons

Lalli, G., Gschmeissner, S., & Schiavo, G. (2003) · Journal of Cell Science · doi:10.1242/jcs.00727 · Cited by 84 · see citing works

Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays

Kiselyov, A. S., Semenova, M. N., Chernyshova, N. B., Leitão, A., Samet, A. V., Kislyi, K. A., Raihstat, M. M., Oprea, T. I., Lemcke, H., Lantow, M., et al. (2010) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2009.12.072 · Cited by 83 · see citing works

Force-Dependent Detachment of Kinesin-2 Biases Track Switching at Cytoskeletal Filament Intersections

Schroeder, H. W., Hendricks, A. G., Ikeda, K., Shuman, H., Rodionov, V., Ikebe, M., Goldman, Y. E., & Holzbaur, E. L. F. (2012) · Biophysical Journal · doi:10.1016/j.bpj.2012.05.037 · Cited by 82 · see citing works

Ezrin Promotes Actin Assembly at the Phagosome Membrane and Regulates Phago‐Lysosomal Fusion

Marion, S., Hoffmann, E., Holzer, D., Clainche, C. L., Martin, M., Sachse, M., Ganeva, I., Mangeat, P. H., & Griffiths, G. W. (2011) · Traffic · doi:10.1111/j.1600-0854.2011.01158.x · Cited by 74 · see citing works

Phosphoinositides Regulate Membrane-dependent Actin Assembly by Latex Bead Phagosomes

Defacque, H., BOS, E. C. W., Garvalov, B. K., Barret, C., Roy, C., Mangeat, P. H., Shin, H., Rybin, V., & Griffiths, G. W. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.01-06-0314 · Cited by 69 · see citing works

The myosin family: unconventional roles of actin-dependent molecular motors in immune cells

Maravillas‐Montero, J. L., & Santos‐Argumedo, L. (2011) · Journal of Leukocyte Biology · doi:10.1189/jlb.0711335 · Cited by 67 · see citing works

Adaptability of myosin V studied by simultaneous detection of position and orientation

Syed, S., Snyder, G. E., Franzini‐Armstrong, C., Selvin, P. R., & Goldman, Y. E. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601060 · Cited by 67 · see citing works

Spatio-temporal Model of Endogenous ROS and Raft-Dependent WNT/Beta-Catenin Signaling Driving Cell Fate Commitment in Human Neural Progenitor Cells

Haack, F., Lemcke, H., Ewald, R., Rharass, T., & Uhrmacher, A. M. (2015) · PLOS Computational Biology · doi:10.1371/journal.pcbi.1004106 · Cited by 66 · see citing works

Phagocytosis and the microtubule cytoskeleton

Harrison, R. E., & Grinstein, S. (2002) · Biochemistry and Cell Biology · doi:10.1139/o02-142 · Cited by 66 · see citing works

Myosin-Va Binds to and Mechanochemically Couples Microtubules to Actin Filaments

Cao, T. T., Chang, W., Masters, S. E., & Mooseker, M. S. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.e03-07-0504 · Cited by 65 · see citing works

Role of microtubules and myosins in Fc gamma receptor-mediated phagocytosis

Araki, N. (2006) · Frontiers in bioscience · doi:10.2741/1897 · Cited by 64 · see citing works

On phagosome individuality and membrane signalling networks

Griffiths, G. W. (2004) · Trends in Cell Biology · doi:10.1016/j.tcb.2004.05.010 · Cited by 62 · see citing works

Myosin-Vb functions as a dynamic tether for peripheral endocytic compartments during transferrin trafficking

Provance, D. W., Addison, E. J., Wood, P. R., Chen, D. Z., Silan, C. M., & Mercer, J. A. (2008) · BMC Cell Biology · doi:10.1186/1471-2121-9-44 · Cited by 60 · see citing works

Annexin A1 is a new functional linker between actin filaments and phagosomes during phagocytosis

Patel, D. M., Ahmad, S. F., Weiss, D. G., Gerke, V., & Kuznetsov, S. A. (2011) · Journal of Cell Science · doi:10.1242/jcs.076208 · Cited by 54 · see citing works

Cyclic AMP promotes a peripheral distribution of melanosomes and stimulates melanophilin/Slac2‐a and actin association

Passeron, T., Bahadoran, P., Bertolotto, C., Chiavérini, C., Buscà, R., Valony, G., Bille, K., Ortonne, J. P., & Ballotti, R. (2004) · The FASEB Journal · doi:10.1096/fj.03-1240fje · Cited by 51 · see citing works

The molecular regulation of organelle transport in mammalian retinal pigment epithelial cells

Futter, C. E. (2006) · Pigment Cell Research · doi:10.1111/j.1600-0749.2006.00303.x · Cited by 50 · see citing works

Squeezing in a Meal: Myosin Functions in Phagocytosis

Barger, S. R., Gauthier, N. C., & Krendel, M. (2019) · Trends in Cell Biology · doi:10.1016/j.tcb.2019.11.002 · Cited by 49 · see citing works

An elegant nano-injection machinery for sabotaging the host: Role of Type III secretion system in virulence of different human and animal pathogenic bacteria

Hajra, D., Nair, A. V., & Chakravortty, D. (2021) · Physics of Life Reviews · doi:10.1016/j.plrev.2021.05.007 · Cited by 48 · see citing works

Phagosomal transport depends strongly on phagosome size

Keller, S., Berghoff, K., & Kress, H. (2017) · Scientific Reports · doi:10.1038/s41598-017-17183-7 · Cited by 48 · see citing works

Lipids regulate P2X7-receptor-dependent actin assembly by phagosomes via ADP translocation and ATP synthesis in the phagosome lumen

Kühnel, M., Rybin, V., Anand, P., Anes, E., & Griffiths, G. W. (2009) · Journal of Cell Science · doi:10.1242/jcs.034199 · Cited by 46 · see citing works

Dynamin A, Myosin IB and Abp1 Couple Phagosome Maturation to F‐Actin Binding

Gopaldass, N., Patel, D. M., Kratzke, R., Dieckmann, R., Hausherr, S., Hagedorn, M., Monroy, R., Krüger, J., Neuhaus, E. M., Hoffmann, E., et al. (2011) · Traffic · doi:10.1111/j.1600-0854.2011.01296.x · Cited by 42 · see citing works

Microfilaments and microtubules regulate recycling from phagosomes

Damiani, M. T. (2003) · Experimental Cell Research · doi:10.1016/s0014-4827(03)00253-2 · Cited by 42 · see citing works

Regulation of tyrosine phosphorylation in macrophage phagocytosis and chemotaxis

Park, H., Ishihara, D., & Cox, D. (2011) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2011.02.019 · Cited by 38 · see citing works

Myosin regulation in the migration of tumor cells and leukocytes within a three-dimensional collagen matrix

Bastian, P., Lang, K. S., Niggemann, B., Zaenker, K. S., & Entschladen, F. (2004) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-004-4391-6 · Cited by 34 · see citing works

Regulatory Control of Both Microtubule‐ and Actin‐dependent Fish Melanosome Movement

Sköld, H. N., Norström, E., & Wallin, M. (2002) · Pigment Cell Research · doi:10.1034/j.1600-0749.2002.02048.x · Cited by 32 · see citing works

Sphingosine-1-phosphate receptors stimulate macrophage plasma-membrane actin assembly via ADP release, ATP synthesis and P2X7R activation

Kühnel, M., Reiss, M., Anand, P., Treede, I., Holzer, D., Hoffmann, E., Klapperstueck, M., Steinberg, T. H., Markwárdt, F., & Griffiths, G. W. (2009) · Journal of Cell Science · doi:10.1242/jcs.034207 · Cited by 31 · see citing works

Synthesis and SAR requirements of adamantane–colchicine conjugates with both microtubule depolymerizing and tubulin clustering activities

Zefirova, O. N., Nurieva, E. V., Shishov, D. V., Baskin, I. I., Fuchs, F., Lemcke, H., Schröder, F. G., Weiss, D. G., Zefirov, N. S., & Kuznetsov, S. A. (2011) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2011.07.040 · Cited by 30 · see citing works

Myosins in melanocytes: to move or not to move?

Coudrier, E. (2007) · Pigment Cell Research · doi:10.1111/j.1600-0749.2007.00376.x · Cited by 29 · see citing works

Initial receptor–ligand interactions modulate gene expression and phagosomal properties during both early and late stages of phagocytosis

Hoffmann, E., Marion, S., Mishra, B. B., John, M., Kratzke, R., Ahmad, S. F., Holzer, D., Anand, P., Weiss, D. G., Griffiths, G. W., et al. (2010) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2010.04.006 · Cited by 28 · see citing works

Spatiotemporal Changes of the Phagosomal Proteome in Dendritic Cells in Response to LPS Stimulation*

Pauwels, A.-M., Härtlová, A., Peltier, J., Driege, Y., Baudelet, G., Brodin, P. M., Trost, M., Beyaert, R., & Hoffmann, E. (2019) · Molecular & Cellular Proteomics · doi:10.1074/mcp.ra119.001316 · Cited by 25 · see citing works

Assessment of myosin II, Va, VI and VIIa loss of function on endocytosis and endocytic vesicle motility in bone marrow‐derived dendritic cells

Holt, J. P., Bottomly, K., & Mooseker, M. S. (2007) · Cell Motility and the Cytoskeleton · doi:10.1002/cm.20220 · Cited by 24 · see citing works

Kinetics of phagosome maturation is coupled to their intracellular motility

Yu, Y., Zhang, Z., Walpole, G. F. W., & Yu, Y. (2022) · Communications Biology · doi:10.1038/s42003-022-03988-4 · Cited by 23 · see citing works

The Structural And Functional Diversity Of The Myosin Family Of Actin-Based Molecular Motors

Mooseker, M. S., & Foth, B. J. (2007) · Springer eBooks · doi:10.1007/978-1-4020-6519-4_1 · Cited by 23 · see citing works

Distinct Roles of Myosin Va in Membrane Remodeling and Exocytosis of Secretory Granules

Kögel, T., Rudolf, R., Hodneland, E., Hellwig, A., Kuznetsov, S. A., Seiler, F., Söllner, T. H., Barroso, J. F., & Gerdes, H. (2010) · Traffic · doi:10.1111/j.1600-0854.2010.01048.x · Cited by 21 · see citing works

Relocation of myosin and actin, kinesin and tubulin in the acrosome reaction of bovine spermatozoa

Oikonomopoulou, I., Patel, H., Watson, P. F., & Chantler, P. D. (2009) · Reproduction Fertility and Development · doi:10.1071/rd08166 · Cited by 18 · see citing works

Neuronal differentiation requires a biphasic modulation of gap junctional intercellular communication caused by dynamic changes of connexin43 expression

Lemcke, H., Nittel, M., Weiss, D. G., & Kuznetsov, S. A. (2013) · European Journal of Neuroscience · doi:10.1111/ejn.12219 · Cited by 17 · see citing works

A guide to measuring phagosomal dynamics

Levin‐Konigsberg, R., & Mantegazza, A. R. (2020) · FEBS Journal · doi:10.1111/febs.15506 · Cited by 16 · see citing works

Melanosomes and MHC class II antigen-processing compartments

Marks, M. S., Theos, A. C., & Raposo, G. (2003) · Immunologic Research · doi:10.1385/ir:27:2-3:409 · Cited by 15 · see citing works

Myosin motors on the pathway of viral infections

Matozo, T., Kogachi, L., & de Alencar, B. C. (2022) · Cytoskeleton · doi:10.1002/cm.21718 · Cited by 14 · see citing works

Modelling phagosomal lipid networks that regulate actin assembly

Kühnel, M., Mayorga, L. S., Dandekar, T., Thakar, J., Schwarz, R. F., Anes, E., Griffiths, G., & Jg, R. (2008) · BMC Systems Biology · doi:10.1186/1752-0509-2-107 · Cited by 14 · see citing works

Synthesis and biological testing of (5Z)-2-aryl-5-arylmethylidene-3,5-dihydro-4H-imidazol-4-ones as antimitotic agents

Beloglazkina, A. A., Wobith, B., Barskaya, E. S., Зефиров, Н. А., Majouga, A. G., Beloglazkina, E. K., Zyk, N. V., Kuznetsov, S. A., & Zefirova, O. N. (2016) · Medicinal Chemistry Research · doi:10.1007/s00044-016-1566-2 · Cited by 14 · see citing works

Novel antimitotic agents related to tubuloclustin: synthesis and biological evaluation

Zefirova, O. N., Nurieva, E. V., Wobith, B., Gogol, V. V., Зефиров, Н. А., ́kov, A. V. O., Shishov, D. V., Zefirov, N. S., & Kuznetsov, S. A. (2017) · Molecular Diversity · doi:10.1007/s11030-017-9739-6 · Cited by 13 · see citing works

Adamantyl-substituted ligands of colchicine binding site in tubulin: different effects on microtubule network in cancer cells

Зефиров, Н. А., Evteeva, Y. A., Wobith, B., Kuznetsov, S. A., & Zefirova, O. N. (2018) · Structural Chemistry · doi:10.1007/s11224-018-1219-9 · Cited by 13 · see citing works

Radiosensitizing effect of epothilone B on human epithelial cancer cells

Baumgart, T., Klautke, G., Kriesen, S., Kuznetsov, S. A., Weiss, D. G., Fietkau, R., Hildebrandt, G., & Manda, K. (2012) · Strahlentherapie und Onkologie · doi:10.1007/s00066-011-0029-4 · Cited by 13 · see citing works

Measuring Stepwise Binding of Thermally Fluctuating Particles to Cell Membranes without Fluorescence

Rohrbach, A., Meyer, T., Stelzer, E. H. K., & Kress, H. (2020) · Biophysical Journal · doi:10.1016/j.bpj.2020.03.005 · Cited by 12 · see citing works

Novel substituted 5‐methyl‐4‐acylaminoisoxazoles as antimitotic agents: Evaluation of selectivity to LNCaP cancer cells

Sadovnikov, K. S., Vasilenko, D. A., Gracheva, Y. A., Зефиров, Н. А., Radchenko, E. V., Palyulin, V. A., Grishin, Y. K., Vasilichin, V. A., Shtil, A. A., Shevtsov, P. N., et al. (2022) · Archiv der Pharmazie · doi:10.1002/ardp.202100425 · Cited by 12 · see citing works

Molecular motors as cargo transporters in the cell—The good, the bad and the ugly

Mallik, R., & Gross, S. P. (2006) · Physica A Statistical Mechanics and its Applications · doi:10.1016/j.physa.2006.05.017 · Cited by 12 · see citing works

Podophyllotoxin esters with alicyclic residues: an insight into the origin of microtubule-curling effect in cancer cells

Зефиров, Н. А., Glaßl, A., Radchenko, E. V., Borovik, A. N., Stanishevskiy, V. V., Milaeva, E. R., Kuznetsov, S. A., & Zefirova, O. N. (2022) · Mendeleev Communications · doi:10.1016/j.mencom.2022.03.006 · Cited by 11 · see citing works

Ninein promotes F-actin cup formation and inward phagosome movement during phagocytosis in macrophages

Omer, S., Li, J., Yang, C. X., & Harrison, R. E. (2023) · Molecular Biology of the Cell · doi:10.1091/mbc.e23-06-0216 · Cited by 10 · see citing works

Reconstituting the Motility of Isolated Intracellular Cargoes

Hendricks, A. G., Goldman, Y. E., & Holzbaur, E. L. F. (2014) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/b978-0-12-397924-7.00014-5 · Cited by 10 · see citing works

A Method for Spatially Resolved Local Intracellular Mechanochemical Sensing and Organelle Manipulation

Shekhar, S., Cambi, A., Figdor, C. G., Subramaniam, V., & Kanger, J. S. (2012) · Biophysical Journal · doi:10.1016/j.bpj.2012.06.010 · Cited by 10 · see citing works

Huntingtin S421 phosphorylation increases kinesin and dynein engagement on early endosomes and lysosomes

Prowse, E. N. P., Chaudhary, A. R., Sharon, D. M., & Hendricks, A. G. (2023) · Biophysical Journal · doi:10.1016/j.bpj.2023.02.006 · Cited by 9 · see citing works

Timing of Phagosome Maturation Depends on Their Transport Switching from Actin to Microtubule Tracks

Yu, Y., Zhang, Z., & Yu, Y. (2023) · The Journal of Physical Chemistry B · doi:10.1021/acs.jpcb.3c05647 · Cited by 8 · see citing works

Novel bridged and caged C4-podophyllotoxin derivatives as microtubule disruptors: synthesis, cytotoxic evaluation and structure–activity relationship

Зефиров, Н. А., Kruth, A., Wobith, B., Nurieva, E. V., Riyaz, S., Reddy, C. V. R., Kuznetsov, S. A., & Zefirova, O. N. (2018) · Mendeleev Communications · doi:10.1016/j.mencom.2018.09.007 · Cited by 7 · see citing works

N-(4-Methoxyphenyl)-substituted bicyclic isothioureas: effect on morphology of cancer cells

Evdokimova, A. V., Alexeev, A., Nurieva, E. V., Milaeva, E. R., Kuznetsov, S. A., & Zefirova, O. N. (2021) · Mendeleev Communications · doi:10.1016/j.mencom.2021.04.003 · Cited by 6 · see citing works

Proteomic analysis of lipopolysaccharide activated human monocytes

Lausen, M., Poulsen, T. B. G., Christiansen, G., Kastaniegaard, K., Stensballe, A., & Birkelund, S. (2018) · Molecular Immunology · doi:10.1016/j.molimm.2018.09.016 · Cited by 5 · see citing works

Novel colchicine conjugate with unusual effect on the microtubules of cancer cells

Zefirova, O. N., Nurieva, E. V., Wobith, B., Schulz, S., Зефиров, Н. А., & Kuznetsov, S. A. (2020) · Pure and Applied Chemistry · doi:10.1515/pac-2019-1215 · Cited by 4 · see citing works

Isolation of Latex Bead-and Mycobacteria-Containing Phagosomes

Kühnel, M., Anes, E., & Griffiths, G. (2006) · Elsevier eBooks · doi:10.1016/b978-012164730-8/50080-0 · Cited by 4 · see citing works

Phagocytosis

Naik, U., & Harrison, R. E. (2013) · Colloquium Series on Building Blocks of the Cell Cell Structure and Function · doi:10.4199/c00081ed1v01y201304bbc004 · Cited by 3 · see citing works

Locomotor Force Generation by Myosins

Jbireal, J. M., Entschladen, F., & Zänker, K. S. (2010) · Translational research in biomedicine · doi:10.1159/000274482 · Cited by 2 · see citing works

The generation of locomotory forces in the spontaneous and norepinephrine‐induced migration of carcinoma cells

Strell, C., Entschladen, F., Bastian, P., Niggemann, B., Zänker, K. S., & Lang, K. (2006) · Signal Transduction · doi:10.1002/sita.200600088 · Cited by 2 · see citing works

Roles of the Actin Cytoskeleton and Myosins in the Endomembrane System

Fath, K. R. (2006) · Advances in molecular and cell biology · doi:10.1016/s1569-2558(06)37006-3 · Cited by 1 · see citing works

Binding and Uptake of Single and Dual-opsonized Target Particles by Macrophages

Naik, U. (2020) · TSpace (University of Toronto) · Cited by 1 · see citing works

TRPML1 positions lysosomes and regulates actin-membrane linkers in astrocyte processesPreprint

Spivey, M. L., Fuller, M. L., Chen, S. J., Sidibe, D. K., Wang, Y., Bhattarai, J. P., Ma, M., & Maday, S. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.26.734916 · Cited by 1 · see citing works

Phagosome Proteomes Unite! A Virtual Model of Maturation as a Tool to Study Pathogen‐Induced Changes

Dieckmann, R., & Soldati, T. (2009) · Wiley eBooks · doi:10.1002/9783527629176.ch7

Phagosome–Cytoskeleton Interactions

Gutierrez, M. G., & Griffiths, G. (2009) · Wiley eBooks · doi:10.1002/9783527629176.ch8

The Effects of Microtubule Stabilizing Drugs on Macrophage Immune-Mediated Endocytosis

Joshi, P. (2010) · doi:10.26686/wgtn.16973734.v1

Vesicular trafficking: 7th Young Scientists Meeting of the German Society for Cell Biology (DGZ) – Jena, September 22nd to 24th, 2005

Duden, R., & Eichinger, L. (2006) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2005.12.001

MERTK-mediated Signaling in the Retinal Pigment Epithelium: Insights into the Mechanism of RPE Phagocytosis.

Shelby, S. J. (2012) · Deep Blue (University of Michigan)

Signaling Pathways in Airway Mucin Secretion: Roles of Protease-Activated Receptor-2, MARCKS, and Related Chaperone and Cytoskeletal Proteins.

Lin, K. (2009) · NCSU Libraries Repository (North Carolina State University Libraries)

A study of microparticle shape and surface chemistry effects on interactions with macrophages

Bruce, G. (2021) · Nottingham ePrints (University of Nottingham)

Identification of a Novel Mycobacterial Gene Involved in the Synthesis of a Phenolic Glycolipid and its Role in the Prevention of Phagosome Maturation

Robinson, N. (2007) · bonndoc (University of Bonn)

Activated Fc receptor supramolecular complex

Petrenko, V. (2021) · doi:10.32920/ryerson.14647710

Many dynein teams collectively generate high forces during the transport of large organelles

Wieland, S., Steininger, C., Gitschier, D. E., Kaiser, M. M., Gross, W., Chaudhary, A. R., Ritschar, J., Laforsch, C., Hendricks, A. G., & Kress, H. (2025) · Biophysical Journal · doi:10.1016/j.bpj.2025.09.012

Reviewer #2 (Public review): TRPML1 positions lysosomes and regulates actin-membrane linkers in astrocyte processes

(2026) · eLife · doi:10.7554/elife.112491.1.sa1

TRPML1 positions lysosomes and regulates actin-membrane linkers in astrocyte processesPreprint

Coughlan, M. L., Fuller, M. L., Chen, S. J., Sidibe, D. K., Wang, Y., Bhattarai, J. P., Ma, M., & Maday, S. (2026) · eLife · doi:10.7554/elife.112491.1

TRPML1 positions lysosomes and regulates actin-membrane linkers in astrocyte processesPreprint

Coughlan, M. L., Fuller, M. L., Chen, S. J., Sidibe, D. K., Wang, Y., Bhattarai, J. P., Ma, M., & Maday, S. (2026) · eLife · doi:10.7554/elife.112491

Directed motility of phagosomes inTetrahymena thermophila requires actin and Myo1p, a novel unconventional myosin

Hosein, R. E., Williams, S. A., & Gavin, R. H. (2005) · Cell Motility and the Cytoskeleton · doi:10.1002/cm.20065 · Cited by 21 · see citing works

A role for microtubule dynamics in phagosome movement

Blocker, A., Griffiths, G. W., Olivo‐Marín, J., Hyman, A. A., & Severin, F. F. (1998) · Journal of Cell Science · doi:10.1242/jcs.111.3.303 · Cited by 84 · see citing works

Actin‐based phagosome motility

Zhang, F., Southwick, F. S., & Purich, D. L. (2002) · Cell Motility and the Cytoskeleton · doi:10.1002/cm.10058 · Cited by 39 · see citing works

Microtubule-associated protein-dependent binding of phagosomes to microtubules

Blocker, A., Severin, F. F., Habermann, A., Hyman, A. A., Griffiths, G., & Burkhardt, J. K. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.7.3803 · Cited by 81 · see citing works

Interactions of actin, myosin, and a new actin-binding protein of rabbit pulmonary macrophages. II. Role in cytoplasmic movement and phagocytosis.

Stossel, T. P., & Hartwig, J. H. (1976) · The Journal of Cell Biology · doi:10.1083/jcb.68.3.602 · Cited by 287 · see citing works