MicroRNA-21 Targets Sprouty2 and Promotes Cellular Outgrowths

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

Lee, R. C., Feinbaum, R. L., & Ambros, V. (1993) · Cell · doi:10.1016/0092-8674(93)90529-y · Cited by 12,948

A microRNA expression signature of human solid tumors defines cancer gene targets

Volinia, S., Calin, G. A., Liu, C.-G., Ambs, S., Cimmino, A., Petrocca, F., Visone, R., Iorio, M., Roldo, C., Ferracin, M., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510565103 · Cited by 5,697

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

Lim, L. P., Lau, N. C., Garrett-Engele, P., Grimson, A., Schelter, J. M., Castle, J., Bartel, D. P., Linsley, P. S., & Johnson, J. M. (2005) · Nature · doi:10.1038/nature03315 · Cited by 4,755

Silencing of microRNAs in vivo with ‘antagomirs’

Krützfeldt, J., Rajewsky, N., Braich, R., Rajeev, K. G., Tuschl, T., Manoharan, M., & Stoffel, M. (2005) · Nature · doi:10.1038/nature04303 · Cited by 3,949

Identification of tissue-specific microRNAs from mouse

Lagos-Quintana, M., Rauhut, R., Yalcin, A., Meyer, J., Lendeckel, W., & Tuschl, T. (2002) · Current Biology · doi:10.1016/s0960-9822(02)00809-6 · Cited by 3,355

MicroRNA-21 Regulates Expression of the PTEN Tumor Suppressor Gene in Human Hepatocellular Cancer

Meng, F., Henson, R., Wehbe–Janek, H., Ghoshal, K., Jacob, S. T., & Patel, T. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.05.022 · Cited by 2,773

MicroRNA-21 Is an Antiapoptotic Factor in Human Glioblastoma Cells

Chan, J. A., Krichevsky, A. M., & Kosik, K. S. (2005) · Cancer Research · doi:10.1158/0008-5472.can-05-0137 · Cited by 2,557

Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts

Bristow, M. R., Ginsburg, R., Minobe, W. A., Cubicciotti, R. S., Sageman, W. S., Lurie, K. G., Billingham, M. E., Harrison, D. C., & Stinson, E. B. (1982) · New England Journal of Medicine · doi:10.1056/nejm198207223070401 · Cited by 2,270

MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells

Ebert, M. S., Neilson, J. R., & Sharp, P. A. (2007) · Nature Methods · doi:10.1038/nmeth1079 · Cited by 2,108

MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer

Asangani, I. A., Rasheed, S. A. K., Nikolova, D. A., Leupold, J. H., Colburn, N. H., Post, S., & Allgayer, H. (2008) · Oncogene · doi:10.1038/sj.onc.1210856 · Cited by 1,882

MicroRNAs: promising biomarkers for diagnosis and therapeutic targets in human colorectal cancer metastasis

Hur, K. (2015) · BMB Reports · doi:10.5483/bmbrep.2015.48.4.007 · Cited by 36

MicroRNA-21 is Induced by Rapamycin in a Model of Tuberous Sclerosis (TSC) and Lymphangioleiomyomatosis (LAM)

Trindade, A. J., Medvetz, D. A., Neuman, N. A., Myachina, F., Yu, J. J., Priolo, C., & Henske, E. P. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060014 · Cited by 36

Kinetics of Circulating MicroRNAs in Response to Cardiac Stress in Patients With Coronary Artery Disease

Jansen, F., Schäfer, L., Wang, H., Schmitz, T., Flender, A., Schueler, R., Hammerstingl, C., Nickenig, G., Sinning, J., & Werner, N. (2017) · Journal of the American Heart Association · doi:10.1161/jaha.116.005270 · Cited by 37

Application of Mutated miR-206 Target Sites Enables Skeletal Muscle-specific Silencing of Transgene Expression of Cardiotropic AAV9 Vectors

Geisler, A., Schön, C., Größl, T., Pinkert, S., Stein, E. A., Kurreck, J., Vetter, R., & Fechner, H. (2013) · Molecular Therapy · doi:10.1038/mt.2012.276 · Cited by 36

microRNA 21‐mediated suppression of sprouty1 by Pokemon affects liver cancer cell growth and proliferation

Jin, X., Sun, Q., Liu, F., Yang, H., Liu, M., Liu, H., Xu, W., & Jiang, Y. (2013) · Journal of Cellular Biochemistry · doi:10.1002/jcb.24504 · Cited by 35

MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid Malignancies

Sionov, R. V. (2013) · ISRN Hematology · doi:10.1155/2013/348212 · Cited by 35

GTPase Activating Protein (Sh3 Domain) Binding Protein 1 Regulates the Processing of MicroRNA-1 during Cardiac Hypertrophy

He, M., Yang, Z., Abdellatif, M., & Sayed, D. H. (2015) · PLoS ONE · doi:10.1371/journal.pone.0145112 · Cited by 35

MicroRNA-21 ablation exacerbates aldosterone-mediated cardiac injury, remodeling, and dysfunction

Syed, M., Ball, J. P., Mathis, K. W., Hall, M. E., Ryan, M. J., Rothenberg, M. E., Cardozo, L. L. Y., & Romero, D. G. (2018) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00155.2018 · Cited by 35

The Emerging Role of miRNAs in HTLV-1 Infection and ATLL Pathogenesis

Moles, R., & Nicot, C. (2015) · Viruses · doi:10.3390/v7072805 · Cited by 38

The S100P/RAGE signaling pathway regulates expression of microRNA‐21 in colon cancer cells

Mercado-Pimentel, M. E., Onyeagucha, B. C., Li, Q., Pimentel, A. C., Jandová, J., & Nelson, M. A. (2015) · FEBS Letters · doi:10.1016/j.febslet.2015.07.010 · Cited by 33

Synthetic RNAs for Gene Regulation: Design Principles and Computational Tools

Laganà, A., Shasha, D. E., & Croce, C. M. (2014) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2014.00065 · Cited by 33

Function Control of Anti-microRNA Oligonucleotides Using Interstrand Cross-Linked Duplexes

Mie, Y., Hirano, Y., Kowata, K., Nakamura, A., Yasunaga, M., Nakajima, Y., & Komatsu, Y. (2017) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2017.11.003 · Cited by 33

Diagnostic and Therapeutic Potential of microRNAs in Acute Kidney Injury

Brandenburger, T., & Lorenzen, J. M. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00657 · Cited by 34

MicroRNA regulation of epithelial plasticity in cancer

D’Amato, N. C., Howe, E. N., & Richer, J. K. (2012) · Cancer Letters · doi:10.1016/j.canlet.2012.11.054 · Cited by 32

MicroRNAs in Cancer Translational Research

Cho, W. C. S. (2011) · Springer eBooks · doi:10.1007/978-94-007-0298-1 · Cited by 32

Current Status and Perspectives Regarding LNA‐Anti‐miR Oligonucleotides and microRNA miR‐21 Inhibitors as a Potential Therapeutic Option in Treatment of Colorectal Cancer

Nedaeinia, R., Avan, A., Ahmadian, M., Nia, S. N., Ranjbar, M., Sharifi, M., Goli, M., Piroozmand, A., Nourmohammadi, E., Manian, M., et al. (2017) · Journal of Cellular Biochemistry · doi:10.1002/jcb.26047 · Cited by 32

Neurotrophin-3 mRNA a putative target of miR21 following status epilepticus

Risbud, R. M., Lee, C., & Porter, B. E. (2011) · Brain Research · doi:10.1016/j.brainres.2011.09.039 · Cited by 31

Extracellular Non-Coding RNAs in Cardiovascular Diseases

Jiapaer, Z., Li, C., Yang, X., Sun, L., Chatterjee, E., Zhang, L., Lei, J., & Li, G. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15010155 · Cited by 32

miR-21 modulates prostaglandin signaling and promotes gastric tumorigenesis by targeting 15-PGDH

Li, L., Wang, X., Li, W., Yang, L., Liu, R., Zeng, R., Wu, Y., & Shou, T. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.09.137 · Cited by 30

Cardiac Insulin Resistance and MicroRNA Modulators

Pulakat, L., Aroor, A. R., Gul, R., & Sowers, J. R. (2011) · Experimental Diabetes Research · doi:10.1155/2012/654904 · Cited by 29

Antisense MicroRNA Therapeutics in Cardiovascular Disease: Quo Vadis?

Philippen, L. E., Dirkx, E., Wit, J. B. M., Burggraaf, K., Windt, L. J. D., & Martins, P. A. D. C. (2015) · Molecular Therapy · doi:10.1038/mt.2015.133 · Cited by 29

miR-21 targets Fas ligand-mediated apoptosis in breast cancer cell line MCF-7

Wu, M., Yang, J., Tao, X., Shi, Y., & Liú, L. (2014) · Journal of Huazhong University of Science and Technology [Medical Sciences] · doi:10.1007/s11596-014-1257-5 · Cited by 28

Post-Transcriptional Regulation by MicroRNA-21 and let-7a MicroRNA in Paediatric Cholesteatoma

Chen, X., & Qin, Z. (2011) · Journal of International Medical Research · doi:10.1177/147323001103900607 · Cited by 29

MicroRNAs in Cardiac Remodeling and Disease

Huang, Z., Neppl, R. L., & Wang, D. (2010) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-010-9165-y · Cited by 28

Subconjunctival injection of antagomir-21 alleviates corneal neovascularization in a mouse model of alkali-burned cornea

Zhang, Y., Zhang, T., Ma, X., & Zou, J. (2016) · Oncotarget · doi:10.18632/oncotarget.14370 · Cited by 27

Circulating plasma microRNAs in the detection of esophageal squamous cell carcinoma

Zhang, L., Dong, B., Ren, P., Ye, H., Shi, J., Qin, J., Wang, K., Wang, P., & Zhang, J. (2018) · Oncology Letters · doi:10.3892/ol.2018.8995 · Cited by 26

Decoding the ubiquitous role of microRNAs in neurogenesis

Nampoothiri, S. S., & Rajanikant, G. K. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-9797-2 · Cited by 26

Cardiac remodeling and pre‐eclampsia: an overview of microRNA expression patterns

Mohseni, Z., Spaanderman, M. E. A., Oben, J., Calore, M., Derksen, E., Al‐Nasiry, S., Windt, L. J. D., & Ghossein‐Doha, C. (2017) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.17516 · Cited by 25

Role and Regulation of MicroRNAs in Aldosterone-Mediated Cardiac Injury and Dysfunction in Male Rats

Ball, J. P., Syed, M., Maranon, R. O., Hall, M. E., Roshan, K. C., Reckelhoff, J. F., Cardozo, L. L. Y., & Romero, D. G. (2017) · Endocrinology · doi:10.1210/en.2016-1707 · Cited by 25

“Locked onto the Target”: Increasing the Efficiency of Antagomirzymes Using Locked Nucleic Acid Modifications

Kaur, H., Scaria, V., & Maiti, S. (2010) · Biochemistry · doi:10.1021/bi101185k · Cited by 25

MicroRNAs in the Evaluation and Potential Treatment of Liver Diseases

Mahgoub, A., & Steer, C. J. (2016) · Journal of Clinical Medicine · doi:10.3390/jcm5050052 · Cited by 24

miR-21 coordinates tumor growth and modulates KRIT1 levels

Orso, F., Balzac, F., Marino, M., Lembo, A., Retta, S. F., & Taverna, D. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.07.031 · Cited by 25

MiR-21 Is under Control of STAT5 but Is Dispensable for Mammary Development and Lactation

Feuermann, Y., Kang, K., Shamay, A., Robinson, G. W., & Hennighausen, L. G. (2014) · PLoS ONE · doi:10.1371/journal.pone.0085123 · Cited by 25

Downregulation of Sprouty homolog 2 by microRNA-21 inhibits proliferation, metastasis and invasion, however promotes the apoptosis of multiple myeloma cells

WANG, J.-H., ZHOU, W.-W., Cheng, S., LIU, B.-X., Liu, F., & SONG, J.-Q. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.3567 · Cited by 24

MicroRNA profiles and potential regulatory pattern during the early stage of spermatogenesis in mice

Luo, M., Hao, L., Hu, F., Dong, Y., Gou, L., Zhang, W., Wang, X., Zhao, Y., Jia, M.-C., Hu, S., et al. (2014) · Science China Life Sciences · doi:10.1007/s11427-014-4737-8 · Cited by 26

Inhibition of miRNA-21 promotes retinal ganglion cell survival and visual function by modulating Müller cell gliosis after optic nerve crush

Li, H., Sun, Z.-L., Pan, Y., Sun, Y., Xu, M., & Feng, D. (2019) · Experimental Cell Research · doi:10.1016/j.yexcr.2019.01.009 · Cited by 23

Signal Transduction Regulators in Axonal Regeneration

Hausott, B., Glueckert, R., Schrott‐Fischer, A., & Klimaschewski, L. P. (2022) · Cells · doi:10.3390/cells11091537 · Cited by 24

A Novel Artificial MicroRNA Expressing AAV Vector for Phospholamban Silencing in Cardiomyocytes Improves Ca2+ Uptake into the Sarcoplasmic Reticulum

Größl, T., Hammer, E., Bien-Möller, S., Geisler, A., Pinkert, S., Röger, C., Poller, W. C., Kurreck, J., Völker, U., Vetter, R., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0092188 · Cited by 22

Inhibition of skin tumor promotion by TPA using a combination of topically applied ursolic acid and curcumin

Tremmel, L., Rho, O., Slaga, T. J., & DiGiovanni, J. (2018) · Molecular Carcinogenesis · doi:10.1002/mc.22918 · Cited by 22

Advances in Natural or Synthetic Nanoparticles for Metastatic Melanoma Therapy and Diagnosis

Arasi, M. B., Pedini, F., Valentini, S., Felli, N., & Felicetti, F. (2020) · Cancers · doi:10.3390/cancers12102893 · Cited by 23

Roles of microRNAs in pressure overload- and ischemia-related myocardial remodeling

Zhou, S., Liu, Y., Prater, K., Zheng, Y., & Cai, L. (2013) · Life Sciences · doi:10.1016/j.lfs.2013.08.023 · Cited by 22

Preferential microRNA targeting revealed by in vivo competitive binding and differential Argonaute immunoprecipitation

Werfel, S., Leierseder, S., Ruprecht, B., Küster, B., & Engelhardt, S. H. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx640 · Cited by 21

MicroRNAs in Rectal Cancer: Functional Significance and Promising Therapeutic Value

Imedio, L., Cristóbal, I., Rubio, J., Santos, A., Rojo, F., & García‐Foncillas, J. (2020) · Cancers · doi:10.3390/cancers12082040 · Cited by 21

Effect of NRG-1/ErbB Signaling Intervention on the Differentiation of Bone Marrow Stromal Cells Into Sinus Node–like Cells

Li, Y., Li, B., Zhang, C.-L., Zhang, J., Zeng, M., & Zheng, Z. (2014) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000068 · Cited by 20

Gas5 inhibition promotes the axon regeneration in the adult mammalian nervous system

Han, X., Xu, J., Chen, Z., Li, P., Zhao, L., Tao, J., Yu, S., Zhu, S., Yu, B., Zhu, J., et al. (2022) · Experimental Neurology · doi:10.1016/j.expneurol.2022.114157 · Cited by 20

Regulation ofSPRY3by X chromosome and PAR2-linked promoters in an autism susceptibility region

Ning, Z., McLellan, A. S., Ball, M., Wynne, F., O’Neill, C., Mills, W. E., Quinn, J. P., Kleinjan, D. A., Anney, R., Carmody, R. J., et al. (2015) · Human Molecular Genetics · doi:10.1093/hmg/ddv231 · Cited by 21

A three serum miRNA panel as diagnostic biomarkers of radiotherapy‑related metastasis in non‑small cell lung cancer

Lv, J., An, J., Zhang, Y.-D., Li, Z.-X., Zhao, G.-L., Gao, J., Hu, W., Chen, H.-M., Li, A., & Jiang, Q. (2020) · Oncology Letters · doi:10.3892/ol.2020.12099 · Cited by 19

MicroRNAs with Mega Functions in Cardiac Remodeling and Repair

Haider, K. H., Khan, M., & Sen, C. K. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-405544-5.00022-8 · Cited by 18

Regulation of microRNA ‐21 expression by natural products in cancer

Shakeri, A., Ghanbari, M., Tasbandi, A., & Sahebkar, A. (2021) · Phytotherapy Research · doi:10.1002/ptr.7069 · Cited by 19

microRNAs involved in psoriasis and cardiovascular diseases

Sileno, S., Beji, S., D'Agostino, M., Carassiti, A., Melillo, G., & Magenta, A. (2021) · Vascular Biology · doi:10.1530/vb-21-0007 · Cited by 17

Prognostic value of candidate microRNAs in gastric cancer: A validation study

Zhang, L., Huang, Z., Zhang, H., Zhu, M., Zhu, W., Xin Min, Z. H. O. U., & Liu, P. (2016) · Cancer Biomarkers · doi:10.3233/cbm-160091 · Cited by 17

Update on the Pathogenic Implications and Clinical Potential of microRNAs in Cardiac Disease

Notari, M., Pulecio, J., & Raya, Á. (2015) · BioMed Research International · doi:10.1155/2015/105620 · Cited by 16

MicroRNA expression patterns of the kidney in hyperuricemia mice treated with Xiezhuo Chubi Decoction (泄浊除痹方)

Sun, W., Zhang, X., Fen-yong, S., Xu, W., Liang, J., Shu-mei, F., & Wang, T. Z. (2011) · Chinese Journal of Integrative Medicine · doi:10.1007/s11655-011-0605-6 · Cited by 16

Curcumin as a promising therapeutic agent for diabetic neuropathy: from molecular mechanisms to functional recovery

Barati, S., Yadegari, A., Shahmohammadi, M., Azami, F., Tahmasebi, F., Rouhani, M. R., Kazemi, S., & Asl, E. R. (2025) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-025-01884-5 · Cited by 21

Roles of microRNAs as non-invasive biomarker and therapeutic target in colorectal cancer.

Wan, T. M.-H., Iyer, D. N., & Ng, L. (2020) · PubMed · doi:10.14670/hh-18-171 · Cited by 15

E2F and microRNA regulation of angiogenesis.

Biyashev, D., & Qin, G. (2011) · Europe PMC (PubMed Central) · Cited by 14

Differential expression of miRNA in rat myocardial tissues under psychological and physical stress

Cui, Y., BAI, Y., WANG, X. D., Liu, B., Zhao, Z., & WANG, L. S. (2014) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2014.1504 · Cited by 14

Expressing MicroRNA Bantam Sponge Drastically Improves the Insecticidal Activity of Baculovirus via Increasing the Level of Ecdysteroid Hormone in Spodoptera exigua Larvae

Ran, Z., Shi, X., Han, F., Li, J., Zhang, Y., Zhou, Y., Yin, J. J., Li, R., & Zhong, J. S. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01824 · Cited by 14

Sprouty keeps bowel kinases regular in colon cancer, while miR-21 targets Sprouty

Frey, M. R., Carraro, G., Batra, R. K., Polk, D. B., & Warburton, D. (2011) · Cancer Biology & Therapy · doi:10.4161/cbt.11.1.14176 · Cited by 13

Expression of microRNA-21 in non-small cell lung cancer tissue increases with disease progression and is likely caused by growth conditional changes during malignant transformation

Haigl, B., Vanas, V., Setinek, U., Hegedűs, B., Gsur, A., & Sutterlüty, H. (2014) · International Journal of Oncology · doi:10.3892/ijo.2014.2272 · Cited by 13

MicroRNAs—Regulators of Signaling Networks in Dilated Cardiomyopathy

Prasad, S. V. N., & Karnik, S. S. (2010) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-010-9177-7 · Cited by 13

Sprouty2 Protein Regulates Hypoxia-inducible Factor-α (HIFα) Protein Levels and Transcription of HIFα-responsive Genes

Hicks, K. C., & Patel, T. B. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.714139 · Cited by 14

Molecular roles of microRNA-21 and exosomal miR-21 in gastrointestinal cancers: diagnostic, therapeutic, and drug resistance insights

Wang, C., Bai, M., Liu, X., Li, Z., Wang, H., & Guo, S. (2025) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2025.1697875 · Cited by 14

MicroRNA associated with atherogenic dyslipidemia in South Asian men

Flowers, E., Singh, K. P., Molina, C. R., Mathur, A., & Aouizerat, B. E. (2013) · International Journal of Cardiology · doi:10.1016/j.ijcard.2013.07.029 · Cited by 12

Silencing the silencer: strategies to inhibit microRNA activity

Reichel, M., Li, J., & Millar, A. A. (2011) · Biotechnology Letters · doi:10.1007/s10529-011-0590-z · Cited by 12

Intracellular Delivery Strategies for MicroRNAs and Potential Therapies for Human Cardiovascular Diseases

Shi, M. A., & Shi, G. (2010) · Science Signaling · doi:10.1126/scisignal.3146pe40 · Cited by 12

Modulation of MicroRNAs for Potential Cancer Therapeutics

Wu, W. (2010) · Methods in molecular biology · doi:10.1007/978-1-60761-863-8_5 · Cited by 12

MicroRNA-21 regulates right ventricular remodeling secondary to pulmonary arterial pressure overload

Chang, W., Fisch, S., Dangwal, S., Mohebali, J., Fiedler, A. G., Chen, M. J., Hsu, C., Yang, Y., Qiu, Y., Alexander, K. M., et al. (2021) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2021.01.003 · Cited by 11

Differential Expression of microRNAs in the Non-Permissive Schistosome Host Microtus fortis under Schistosome Infection

Han, H., Peng, J., Han, Y., Zhang, M., Hong, Y., Fu, Z., Yang, J., Tao, J., & Lin, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0085080 · Cited by 11

G3bp1 – microRNA-1 axis regulates cardiomyocyte hypertrophy

Alikunju, S., Niranjan, N., Mohsin, M., Sayed, N., & Sayed, D. H. (2022) · Cellular Signalling · doi:10.1016/j.cellsig.2022.110245 · Cited by 11

Aberrant Expression of miR-592 Is Associated with Prognosis and Progression of Renal Cell Carcinoma

Lv, X., Shen, J., Guo, Z., Kong, L., Zhou, G., & Ning, H. (2019) · OncoTargets and Therapy · doi:10.2147/ott.s227834 · Cited by 10

Physiological and Pathological Functions of Mammalian MicroRNAs

Liu, M., Jiang, S., Lu, Z., Li, Y., & Young, K. H. (2010) · Elsevier eBooks · doi:10.1016/b978-0-08-046884-6.00223-2 · Cited by 10

Correlation between microRNA-21 and sprouty homolog 2 gene expression in multiple myeloma

WANG, J.-H., Zheng, W., Cheng, S., LIU, B.-X., Liu, F., & SONG, J.-Q. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.3280 · Cited by 10

MicroRNAs as Therapeutic Targets for Cancer

Cheng, G., Danquah, M. K., & Mahato, R. I. (2009) · Springer eBooks · doi:10.1007/978-1-4419-0131-6_14 · Cited by 9

Cardiac Disease Status Dictates Functional mRNA Targeting Profiles of Individual MicroRNAs

Matkovich, S. J., Dorn, G. W., Grossenheider, T. C., & Hecker, P. A. (2015) · Circulation Cardiovascular Genetics · doi:10.1161/circgenetics.115.001237 · Cited by 9

MicroRNAs With Mega Functions in Cardiac Remodeling and Repair: The Micromanagement of Matters of the Heart

Haider, K. H., Khan, M., & Sen, C. K. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-820719-2.00015-6 · Cited by 9

Macro and Small over Micro: Macromolecules and Small Molecules that Regulate MicroRNAs

Kang, S., Im, K., Baek, J., Yoon, S., & Min, H. (2014) · ChemBioChem · doi:10.1002/cbic.201402007 · Cited by 9

The Therapeutic Potential of RNA Interference: Novel Approaches for Cancer Treatment

Okamoto, K., & Murawaki, Y. (2012) · Current Pharmaceutical Biotechnology · doi:10.2174/138920112802501944 · Cited by 9

The Role of Noncoding RNAs in Prostate Cancer

Hasegawa, T., Lewis, H., & Esquela‐Kerscher, A. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800553-8.00012-3 · Cited by 10

Following MicroRNAs Through the Cancer Metastatic Cascade

Grisard, E., & Nicoloso, M. S. (2017) · International review of cytology · doi:10.1016/bs.ircmb.2017.04.005 · Cited by 8

Renal Sympathetic Denervation in Rats Ameliorates Cardiac Dysfunction and Fibrosis Post-Myocardial Infarction Involving MicroRNAs

Zheng, X., Li, X., Lyu, Y., He, Y., Wan, W., & Jiang, X. (2016) · Medical Science Monitor · doi:10.12659/msm.898105 · Cited by 8

Mapping Genetic Variants Associated with Beta-Adrenergic Responses in Inbred Mice

Hersch, M., Peter, B., Kang, H. M., Schüpfer, F., Abriel, H., Pedrazzini, T., Eskin, E., Beckmann, J. S., Bergmann, S., & Maurer, F. (2012) · PLoS ONE · doi:10.1371/journal.pone.0041032 · Cited by 7

Crosstalk between microRNA-21–5p and the transcription factor Dec1 maintains osteoblast function

Kurita, T., Li, X., & BHAWAL, U. K. (2022) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2022.09.090 · Cited by 7

Targeted Lentiviral Vectors: Current Applications and Future Potential

Goyvaerts, C., Liechtenstein, T., Bricogne, C., Escors, D., & Breckpot, K. (2013) · InTech eBooks · doi:10.5772/52770 · Cited by 8

Induction of differentiation-specific miRNAs in TPA-induced myeloid leukemia cells through MEK/ERK activation

Wang, J., Liu, L., Xie, L., Xiang, G., & Zhou, Y. (2012) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2012.1191 · Cited by 7

Paediatrics congenital heart disease is associated with plasma miRNAs

González-Moyotl, N. J., Huesca‐Gómez, C., Torres-Paz, Y. E., Fuentevilla-Álvarez, G., Romero-Maldonado, S., Sámano, R., Soto, M. E., Rosas, M., Domínguez‐López, A., & Gamboa, R. (2024) · Pediatric Research · doi:10.1038/s41390-024-03230-3 · Cited by 6

Integrative Analysis of miR-21, PTEN, and Immune Signatures in Colorectal Cancer

Yen, Y., Hsu, C.-I., Chen, Y., & Tsai, S. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262412118 · Cited by 6

miR-181a/MSC-Loaded Nano-Hydroxyapatite/Collagen Accelerated Bone Defect Repair in Rats by Targeting Ferroptosis Pathway

Xu, X., Feng, J., Lin, T., Liu, R., & Chen, Z. (2024) · Journal of Functional Biomaterials · doi:10.3390/jfb15120385 · Cited by 6

MicroRNAs Challenge the Status Quo of Therapeutic Targeting

Sayed, D. H., Rane, S., & Abdellatif, M. (2008) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-008-9052-y · Cited by 6

Noncoding RNAs Regulating Cancer Signaling Network

Hu, J. Y., Markowitz, G. J., & Wang, X. (2016) · Advances in experimental medicine and biology · doi:10.1007/978-981-10-1498-7_11 · Cited by 6

Overcoming Drug Resistance in Colorectal Cancer by MicroRNAs

Yu, Y., Nangia‐Makker, P., & Majumdar, A. P. N. (2014) · Springer eBooks · doi:10.1007/978-3-319-05134-5_8 · Cited by 5

MicroRNAs and Endothelial Dysfunction in Relation to Obesity and Type 2 Diabetes

Karolina, D. S. (2014) · Journal of Molecular and Genetic Medicine · doi:10.4172/1747-0862.s1-011 · Cited by 5

Enhancing the therapeutic potential of curcumin: a novel nanoformulation for targeted anticancer therapy to colorectal cancer with reduced miR20a and miR21 expression

Atwan, Q. S., & Al-Ogaidi, I. A. Z. (2024) · Biomedical Materials · doi:10.1088/1748-605x/ad1dfc · Cited by 4

A Versatile Tool for Stable Inhibition of microRNA Activity

Pelucchi, P., Tria, V., Martino, V., Sabour, D., Bertalot, G., Molgora, S., Palizban, M., Götte, M., Zucchi, I., & Reinbold, R. A. (2013) · Biology · doi:10.3390/biology2030861 · Cited by 4

The impact of X-rays on the expressions of miR-130a/miR-25 and its potential role in the enhanced metastasis of A549 cell lines in vitro induced by X-rays

Lv, J., Wang, S., Song, X., Li, X., He, R., Yu, H., Chen, S., Wang, L., & Jiang, Q. (2013) · Science China Technological Sciences · doi:10.1007/s11431-013-5290-6 · Cited by 4

Sprouty2 mediated tuning of signalling is essential for somite myogenesis

Abu-Elmagd, M. M., Goljanek‐Whysall, K., Wheeler, G. N., & Münsterberg, A. (2015) · BMC Medical Genomics · doi:10.1186/1755-8794-8-s1-s8 · Cited by 4

Temas de actualidad en insuficiencia cardiaca

Colet, J. C., Aguilera, R. M., Castillo, J. J. C., & Delgado, J. F. (2009) · Revista Española de Cardiología · doi:10.1016/s0300-8932(09)70044-2 · Cited by 4

MicroRNA in the diagnosis of chronic heart failure: state of the problem and the results of a pilot study

Жиров, И. В., Кочетов, А. Г., Zaseeva, A. V., Liang, O. V., Skvortsov, A. A., Abramov, A. A., Рашитович, Г. Р., Masenko, V. P., & Tereshchenko, S. N. (2016) · Systemic Hypertension · doi:10.26442/sg29129 · Cited by 5

The Role of microRNAs in Cancer

Leva, G. D., & Croce, C. M. (2015) · Wiley eBooks · doi:10.1002/9781118468678.ch8 · Cited by 6

Abstract 342: Upregulation Of Mir-21 During Cardiac Hypertrophy Induces Down-regulation Of An Inhibitor Of The Ras-MAPK Pathway, Sprouty 2

Sayed, D. H., He, M., Chen, L.-Y., Lypowy, J., & Abdellatif, M. (2007) · Circulation · doi:10.1161/circ.116.suppl_16.ii_51

Interplay between microRNA-21 and Sprouty2 in non small cell lung cancer-derived cell lines

Vanas, V. (2012) · University of Vienna · doi:10.25365/thesis.22750

Sprouty keeps bowel kinases regular in colon cancer, while miR-21 targets Sprouty

Frey, M. R., Carraro, G., Batra, R. K., Polk, D. B., & Warburton, D. (2011) · Cancer Biology & Therapy · doi:10.4161/cbt.11.1.14176 · Cited by 13

MicroRNA-21 induces stemness by downregulating transforming growth factor beta receptor 2 (TGF R2) in colon cancer cells

Yu, Y., Kanwar, S. S., Patel, B. B., Oh, P., Nautiyal, J., Sarkar, F. H., & Majumdar, A. P. N. (2011) · Carcinogenesis · doi:10.1093/carcin/bgr246 · Cited by 259

Abstract 3550: Overexpression Of Mir-21 Delays The Onset Of Cardiac Failure

Sayed, D. H., He, M., Hong, C., Rane, S., Gao, S., & Abdellatif, M. (2008) · Circulation