Identification of tissue-specific microRNAs from mouse

Lagos-Quintana, Mariana; Rauhut, Reinhard; Yalcin, Abdullah; Meyer, Jutta; Lendeckel, Winfried; Tuschl, Thomas

doi:10.1016/s0960-9822(02)00809-6

Cited by 2,859

Identification of tissue-specific microRNAs from mouse

Lagos-Quintana, Mariana, Rauhut, Reinhard, Yalcin, Abdullah, Meyer, Jutta, Lendeckel, Winfried, Tuschl, Thomas·2002·Current Biology

DOI 10.1016/s0960-9822(02)00809-6

Open this paper in CoChat — free account

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/s0960-9822(02)00809-6

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The brain-specific expression of miR-124a has been demonstrated previously.
“the brain-specific expression of miR-124a [40] has been demonstrated previously [39,40].”
From Expression of miR-15/107 Family MicroRNAs in Human Tissues and Cultured Rat Brain Cells (2014) · cites this paper as [40]
The neuronal cluster included miR-124, a miRNA especially abundant in neurons, affirming specificity of methodology.
“The neuronal cluster included miR-124, a miRNA that is especially abundant in neurons affirming the specificity of the methodology [20]–[22].”
From MicroRNA 146a (miR-146a) Is Over-Expressed during Prion Disease and Modulates the Innate Immune Response and the Microglial Activation State (2012) · cites this paper as [20]
This study confirms the expression of previously cloned miRNAs.
“This study confirms the expression of previously cloned miRNAs [1-3,9,10]”
From Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation (2004) · cites this paper as [2]
The panel of organs tested did not include all the organs and tissues that miRNAs were cloned from, and thus some organ-specific or organ-enriched miRNAs may be expressed in additional organs or tissues.
“The panel of organs that we tested in our study did not include all the organs and tissues that miRNAs were cloned from [1-3,9,10], and thus some organ-specific or organ-enriched miRNAs may be expressed in additional organs or tissues.”
From Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation (2004) · cites this paper as [2]
We observed some discrepancies between our expression profiling by northern analysis and expression profiling by cloning, particularly for certain less-abundant miRNAs represented in size-selected RNA libraries by three or fewer copies.
“we observed some discrepancies between our expression profiling by northern analysis and expression profiling by cloning [2,3]. This is particularly so for certain less-abundant miRNAs - those that were represented in size-selected RNA libraries by three or fewer copies.”
From Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation (2004) · cites this paper as [2]

Our characterization of organ expression of miRNAs correlates with the organ(s) from which these miRNAs were originally cloned.
“Our characterization of organ expression of miRNAs correlates with the organ(s) from which these miRNAS were originally cloned [2,3].”
From Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation (2004) · cites this paper as [2]
mir-142s/mir-142as are located in the junction of the t(8;17) chromosomal rearrangement, which fuses Bcl3 and Myc genes and results in an aggressive B-cell leukemia.
“Notably, mir-142s/mir-142as are located in the junction of the t(8;17) chromosomal rearrangement. This translocation fuses Bcl3 and Myc genes, thus resulting in an aggressive B-cell leukemia [2,37].”
From Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation (2004) · cites this paper as [2]
Many miRNAs have been isolated from mammalian embryonic neurons and mature brain, and some of them are neuronal-specific.
“Many miRNAs have been isolated from mammalian embryonic neurons and mature brain, and some of them are neuronalspecific (Lagos-Quintana et al. 2002;Dostie et al. 2003).”
From A microRNA array reveals extensive regulation of microRNAs during brain development (2003) · cites this paper as Lagos-Quintana et al. 2002
Early publications of general miRNA expression focused on tissues, which comprise numerous cell types, and the localization of miRNAs, whether cell specific or ubiquitous, has not been established.
“The second is that early publications of general miRNA expression focused on tissues, which comprise numerous cell types, and the localization of miRNAs, whether cell specific or ubiquitous, has not been established [8, 9].”
From A curated human cellular microRNAome based on 196 primary cell types (2022) · cites this paper as [8]
miRNAs that were abundantly cloned in a particular organ, such as miR-135 and miR-153 from brain, were exclusively detected by northern analysis in mouse and human brain.
“miRNAs that were abundantly cloned in a particular organ, such as miR-135 and miR-153 from brain [2], were exclusively detected by northern analysis in mouse and human brain.”
From Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation (2004) · cites this paper as [2]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
Lee, R. C., Feinbaum, R. L., & Ambros, V. (1993) · Cell · doi:10.1016/0092-8674(93)90529-y · Cited by 12,948 · see citing works
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
Wightman, B., Ha, I., & Ruvkun, G. (1993) · Cell · doi:10.1016/0092-8674(93)90530-4 · Cited by 4,292 · see citing works

Flagged first, then by citations

Research works printed but not linked: 7

[1]1. Ambros, V. microRNAstiny regulators with great potential Cell. 2001; 107:823-826 Full Text Full Text (PDF) Scopus (1521) PubMed Google Scholar
[2]2. Moss, E.G. MicroRNAshidden in the genome Curr. Biol. 2002; 12:R138-R140 Full Text Full Text (PDF) Scopus (103) PubMed Google Scholar
[3]3. Lagos-Quintana, M. ∙ Rauhut, R. ∙ Lendeckel, W. ... Identification of novel genes coding for small expressed RNAs Science. 2001; 294:853-858 Crossref Scopus (4148) PubMed Google Scholar
[4]4. Lau, N.C. ∙ Lim, L.P. ∙ Weinstein, E.G. ... An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans Science. 2001; 294:858-862 Crossref Scopus (2783) PubMed Google Scholar
[5]5. Lee, R.C. ∙ Ambros, V. An extensive class of small RNAs in Caenorhabditis elegans Science. 2001; 294:862-864 Crossref Scopus (2405) PubMed Google Scholar
[6]6. Pasquinelli, A.E. ∙ Reinhart, B.J. ∙ Slack, F. ... Conservation of the sequence of let-7 heterochronic regulatory RNA Nature. 2000; 408:86-89 Crossref Scopus (1975) PubMed Google Scholar
[7]7. Ambros, V. ∙ Horvitz, H.R. Heterochronic mutants of the nematode Caenorhabditis elegans Science. 1984; 226:409-416 Crossref Scopus (630) PubMed Google Scholar

Sorted by citations

A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing
Landgraf, P., Rusu, M., Sheridan, R., Sewer, A., Iovino, N., Aravin, A., Pfeffer, S., Rice, A., Kamphorst, A. O., Landthaler, M., et al. (2007) · Cell · doi:10.1016/j.cell.2007.04.040 · Cited by 3,626 · see citing works
Self-citation
miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting
Esau, C., Davis, S., Murray, S. F., Yu, X. X., Pandey, S. K., Pear, M., Watts, L., Booten, S. L., Graham, M., McKay, R., et al. (2006) · Cell Metabolism · doi:10.1016/j.cmet.2006.01.005 · Cited by 2,082 · see citing works
Requirement of bic/microRNA-155 for Normal Immune Function
Rodriguez, A., Vigorito, E., Clare, S., Warren, M. V., Couttet, P., Soond, D. R., van Dongen, S., Grocock, R. J., Das, P. P., Miska, E. A., et al. (2007) · Science · doi:10.1126/science.1139253 · Cited by 1,833 · see citing works
A brain-specific microRNA regulates dendritic spine development
Schratt, G. M., Tuebing, F., Nigh, E. A., Kane, C. G., Sabatini, M. E., Kiebler, M., & Greenberg, M. E. (2006) · Nature · doi:10.1038/nature04367 · Cited by 1,786 · see citing works
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
Grimm, D., Streetz, K. L., Jopling, C. L., Storm, T. A., Pandey, K., Davis, C. R., Marion, P., Salazar, F., & Kay, M. A. (2006) · Nature · doi:10.1038/nature04791 · Cited by 1,677 · see citing works
Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
Sempere, L. F., Freemantle, S., Pitha-Rowe, I., Moss, E., Dmitrovsky, E., & Ambros, V. (2004) · Genome Biology · doi:10.1186/gb-2004-5-3-r13 · Cited by 1,578 · see citing works
The Widespread Impact of Mammalian MicroRNAs on mRNA Repression and Evolution
Farh, K. K.-H., Grimson, A., Jan, C., Lewis, B. P., Johnston, W. K., Lim, L. P., Burge, C. B., & Bartel, D. P. (2005) · Science · doi:10.1126/science.1121158 · Cited by 1,484 · see citing works
The MicroRNA miR-124 Promotes Neuronal Differentiation by Triggering Brain-Specific Alternative Pre-mRNA Splicing
Makeyev, E. V., Zhang, J., Carrasco, M. A., & Maniatis, T. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.07.015 · Cited by 1,395 · see citing works
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME
Godoy, P., Hewitt, N. J., Albrecht, U., Andersen, M. E., Ansari, N., Bhattacharya, S., Bode, J. G., Bolleyn, J., Borner, C., Böttger, J., et al. (2013) · Archives of Toxicology · doi:10.1007/s00204-013-1078-5 · Cited by 1,280 · see citing works
A microRNA array reveals extensive regulation of microRNAs during brain development
KRICHEVSKY, A. M., KING, K. S., DONAHUE, C. P., KHRAPKO, K., & KOSIK, K. S. (2003) · RNA · doi:10.1261/rna.5980303 · Cited by 1,040 · see citing works
Regulation of miRNA expression during neural cell specification
Smirnova, L., Gräfe, A., Seiler, A., Schumacher, S., Nitsch, R., & Wulczyn, F. G. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.03978.x · Cited by 707 · see citing works
Lin28: Primal Regulator of Growth and Metabolism in Stem Cells
Shyh-Chang, N., & Daley, G. Q. (2013) · Cell Stem Cell · doi:10.1016/j.stem.2013.03.005 · Cited by 458 · see citing works
Distinct subsets of microRNAs are expressed differentially in the human placentas of patients with preeclampsia
Pineles, B. L., Romero, R., Montenegro, D., Tarca, A. L., Han, Y. M., Kim, Y. M., Draghici, S., Espinoza, J., Kusanovic, J. P., Mittal, P., et al. (2007) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2007.01.008 · Cited by 450 · see citing works
Matrix-bound nanovesicles within ECM bioscaffolds
Huleihel, L., Hussey, G. S., Naranjo, J. D., Zhang, L., Dziki, J. L., Turner, N. J., Stolz, D. B., & Badylak, S. F. (2016) · Science Advances · doi:10.1126/sciadv.1600502 · Cited by 387 · see citing works
MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system
Kapsimali, M., Kloosterman, W. P., de Bruijn, E., Rosa, F., Plasterk, R. H., & Wilson, S. W. (2007) · Genome Biology · doi:10.1186/gb-2007-8-8-r173 · Cited by 376 · see citing works
MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths
Sayed, D., Rane, S., Lypowy, J., He, M., Chen, I.-Y., Vashistha, H., Yan, L., Malhotra, A., Vatner, D., & Abdellatif, M. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e08-02-0159 · Cited by 355 · see citing works
miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex
De Pietri Tonelli, D., Pulvers, J. N., Haffner, C., Murchison, E. P., Hannon, G. J., & Huttner, W. B. (2008) · Development · doi:10.1242/dev.025080 · Cited by 343 · see citing works
MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development
Boutz, P. L., Chawla, G., Stoilov, P., & Black, D. L. (2007) · Genes & Development · doi:10.1101/gad.1500707 · Cited by 304 · see citing works
Comprehensive expression analyses of neural cell-type-specific miRNAs identify new determinants of the specification and maintenance of neuronal phenotypes
Jovičić, A., Roshan, R., Moisoi, N., Pradervand, S., Moser, R., Pillai, B., & Luthi-Carter, R. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.0600-12.2013 · Cited by 251 · see citing works
Noncoding <scp>RNA</scp>s in disease
Lekka, E., & Hall, J. (2018) · FEBS Letters · doi:10.1002/1873-3468.13182 · Cited by 251 · see citing works
Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome
Kahlem, P., Sultan, M., Herwig, R., Steinfath, M., Balzereit, D., Eppens, B., Saran, N. G., Pletcher, M. T., South, S. T., Stetten, G., et al. (2004) · Genome Research · doi:10.1101/gr.1951304 · Cited by 249 · see citing works
Microglia secrete miR-146a-5p-containing exosomes to regulate neurogenesis in depression
Fan, C., Li, Y., Lan, T., Wang, W., Long, Y., & Yu, S. Y. (2022) · Molecular Therapy · doi:10.1016/j.ymthe.2021.11.006 · Cited by 227 · see citing works
An updated role of microRNA-124 in central nervous system disorders: a review
Sun, Y., Luo, Z.-M., Guo, X.-M., Su, D.-F., & Liu, X. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00193 · Cited by 223 · see citing works
Transcriptome-wide Discovery of microRNA Binding Sites in Human Brain
Boudreau, R. L., Jiang, P., Gilmore, B. L., Spengler, R. M., Tirabassi, R., Nelson, J. A., Ross, C. A., Xing, Y., & Davidson, B. L. (2014) · Neuron · doi:10.1016/j.neuron.2013.10.062 · Cited by 217 · see citing works
miR-155 in cancer drug resistance and as target for miRNA-based therapeutics
Bayraktar, R., & Van Roosbroeck, K. (2018) · Cancer and Metastasis Reviews · doi:10.1007/s10555-017-9724-7 · Cited by 216 · see citing works
Chromosome 1p21.3 microdeletions comprising DPYD and MIR137 are associated with intellectual disability
Willemsen, M. H., Vallès, A., Kirkels, L. A. M. H., Mastebroek, M., Olde Loohuis, N., Kos, A., Wissink-Lindhout, W. M., de Brouwer, A. P. M., Nillesen, W. M., Pfundt, R., et al. (2011) · Journal of Medical Genetics · doi:10.1136/jmedgenet-2011-100294 · Cited by 202 · see citing works
MicroRNA-124 is a subventricular zone neuronal fate determinant
Akerblom, M., Sachdeva, R., Barde, I., Verp, S., Gentner, B., Trono, D., & Jakobsson, J. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0558-12.2012 · Cited by 207 · see citing works
General Principals of miRNA Biogenesis and Regulation in the Brain
O'Carroll, D., & Schaefer, A. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2012.87 · Cited by 205 · see citing works
Spatial sorting enables comprehensive characterization of liver zonation
Ben-Moshe, S., Shapira, Y., Moor, A. E., Halpern, K. B., & Itzkovitz, S. (2019) · doi:10.1101/529784 · Cited by 205 · see citing works
Spatial sorting enables comprehensive characterization of liver zonation
Ben-Moshe, S., Shapira, Y., Moor, A. E., Manco, R., Veg, T., Bahar Halpern, K., & Itzkovitz, S. (2019) · Nature Metabolism · doi:10.1038/s42255-019-0109-9 · Cited by 205 · see citing works
Reexamining assumptions about miRNA-guided gene silencing
Kilikevicius, A., Meister, G., & Corey, D. R. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkab1256 · Cited by 194 · see citing works
MiR-137: an important player in neural development and neoplastic transformation
Mahmoudi, E., & Cairns, M. J. (2017) · Molecular Psychiatry · doi:10.1038/mp.2016.150 · Cited by 198 · see citing works
CPEB and two poly(A) polymerases control miR-122 stability and p53 mRNA translation
Burns, D. M., D’Ambrogio, A., Nottrott, S., & Richter, J. D. (2011) · Nature · doi:10.1038/nature09908 · Cited by 193 · see citing works
MicroRNAs and neurodegeneration: role and impact
Abe, M., & Bonini, N. M. (2013) · Trends in Cell Biology · doi:10.1016/j.tcb.2012.08.013 · Cited by 190 · see citing works
Viral Strategies for Targeting the Central and Peripheral Nervous Systems
Bedbrook, C. N., Deverman, B. E., & Gradinaru, V. (2018) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-080317-062048 · Cited by 168 · see citing works
Tissue-specific and reversible RNA interference in transgenic mice
Dickins, R. A., McJunkin, K., Hernando, E., Premsrirut, P. K., Krizhanovsky, V., Burgess, D. J., Kim, S. Y., Cordon-Cardo, C., Zender, L., Hannon, G. J., et al. (2007) · Nature Genetics · doi:10.1038/ng2045 · Cited by 174 · see citing works
MicroRNA-124 loaded nanoparticles enhance brain repair in Parkinson's disease
Saraiva, C., Paiva, J., Santos, T., Ferreira, L., & Bernardino, L. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.06.005 · Cited by 169 · see citing works
Emerging role of microRNAs in major depressive disorder: diagnosis and therapeutic implications
Dwivedi, Y. (2014) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2014.16.1/ydwivedi · Cited by 169 · see citing works
Next-generation AAV vectors—Do not judge a virus (only) by its cover
Domenger, C., & Grimm, D. (2019) · Human Molecular Genetics · doi:10.1093/hmg/ddz148 · Cited by 147 · see citing works
Toward the human cellular microRNAome
McCall, M. N., Kim, M.-S., Adil, M., Patil, A. H., Lu, Y., Mitchell, C. J., Leal-Rojas, P., Xu, J., Kumar, M., Dawson, V. L., et al. (2017) · Genome Research · doi:10.1101/gr.222067.117 · Cited by 151 · see citing works
MicroRNA 146a (miR-146a) Is Over-Expressed during Prion Disease and Modulates the Innate Immune Response and the Microglial Activation State
Saba, R., Gushue, S., Huzarewich, R. L. C. H., Manguiat, K., Medina, S., Robertson, C., & Booth, S. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030832 · Cited by 151 · see citing works
miR-10b-5p expression in Huntington’s disease brain relates to age of onset and the extent of striatal involvement
Hoss, A. G., Labadorf, A., Latourelle, J. C., Kartha, V. K., Hadzi, T. C., Gusella, J. F., MacDonald, M. E., Chen, J.-F., Akbarian, S., Weng, Z., et al. (2015) · BMC Medical Genomics · doi:10.1186/s12920-015-0083-3 · Cited by 151 · see citing works
Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: Unraveling the genome to understand the mind
Hsieh, J., & Eisch, A. J. (2010) · Neurobiology of Disease · doi:10.1016/j.nbd.2010.01.008 · Cited by 144 · see citing works
Investigation of MicroRNA Expression in Human Serum During the Aging Process
Zhang, H., Yang, H., Zhang, C., Jing, Y., Wang, C., Liu, C., Zhang, R., Wang, J., Zhang, J., Zen, K., et al. (2015) · The Journals of Gerontology: Series A · doi:10.1093/gerona/glu145 · Cited by 123 · see citing works
Macrophage development from HSCs requires PU.1-coordinated microRNA expression
Ghani, S., Riemke, P., Schönheit, J., Lenze, D., Stumm, J., Hoogenkamp, M., Lagendijk, A., Heinz, S., Bonifer, C., Bakkers, J., et al. (2011) · Blood · doi:10.1182/blood-2011-02-335141 · Cited by 123 · see citing works
The roles of microRNAs in mouse development
DeVeale, B., Swindlehurst-Chan, J., & Blelloch, R. (2021) · Nature Reviews Genetics · doi:10.1038/s41576-020-00309-5 · Cited by 121 · see citing works
Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies
Fraczek, J., Bolleyn, J., Vanhaecke, T., Rogiers, V., & Vinken, M. (2013) · Archives of Toxicology · doi:10.1007/s00204-012-0983-3 · Cited by 119 · see citing works
Everything you wanted to know about small RNA but were afraid to ask
Boyd, S. D. (2008) · Laboratory Investigation · doi:10.1038/labinvest.2008.32 · Cited by 108 · see citing works
Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins
Lee, J., Mou, H., Ibraheim, R., Liang, S.-Q., Liu, P., Xue, W., & Sontheimer, E. J. (2019) · RNA · doi:10.1261/rna.071704.119 · Cited by 100 · see citing works
Alterations of microRNA-124 expression in peripheral blood mononuclear cells in pre- and post-treatment patients with major depressive disorder
He, S., Liu, X., Jiang, K., Peng, D., Hong, W., Fang, Y., Qian, Y., Yu, S., & Li, H. (2016) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2016.03.015 · Cited by 94 · see citing works
Changes in miRNA-132 and miR-124 levels in non-treated and citalopram-treated patients with depression
Fang, Y., Qiu, Q., Zhang, S., Sun, L., Li, G., Xiao, S., & Li, X. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.11.090 · Cited by 90 · see citing works
Brain‐derived neurotrophic factor expression is repressed during myogenic differentiation by miR‐206
Miura, P., Amirouche, A., Clow, C., Bélanger, G., & Jasmin, B. J. (2012) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07583.x · Cited by 92 · see citing works
Expression of miR-15/107 Family MicroRNAs in Human Tissues and Cultured Rat Brain Cells
Wang, W.-X., Danaher, R. J., Miller, C. S., Berger, J. R., Nubia, V. G., Wilfred, B. S., Neltner, J. H., Norris, C. M., & Nelson, P. T. (2014) · Genomics, Proteomics & Bioinformatics · doi:10.1016/j.gpb.2013.10.003 · Cited by 67 · see citing works
MicroRNA-124: A Key Player in Microglia-Mediated Inflammation in Neurological Diseases
Zhao, J., He, Z., & Wang, J. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.771898 · Cited by 66 · see citing works
Muscle cell communication in development and repair
Demonbreun, A. R., & McNally, E. M. (2017) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2017.03.008 · Cited by 64 · see citing works
cDNA cloning, gene organization and variant specific expression of HIF-1α in high altitude yak (Bos grunniens)
Dolt, K. S., Mishra, M. K., Karar, J., Baig, M. A., Ahmed, Z., & Pasha, M. A. Q. (2007) · Gene · doi:10.1016/j.gene.2006.08.004 · Cited by 65 · see citing works
MicroRNAs and miRceptors: a new mechanism of action for intercellular communication
Fabbri, M. (2018) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2016.0486 · Cited by 65 · see citing works
The Protective Effect of Exercise in Neurodegenerative Diseases: The Potential Role of Extracellular Vesicles
Fuller, O. K., Whitham, M., Mathivanan, S., & Febbraio, M. A. (2020) · Cells · doi:10.3390/cells9102182 · Cited by 60 · see citing works
Synaptosomes secrete and uptake functionally active micro<scp>RNA</scp>s via exocytosis and endocytosis pathways
Xu, J., Chen, Q., Zen, K., Zhang, C., & Zhang, Q. (2013) · Journal of Neurochemistry · doi:10.1111/jnc.12057 · Cited by 61 · see citing works
MicroRNA-Restricted Transgene Expression in the Retina
Karali, M., Manfredi, A., Puppo, A., Marrocco, E., Gargiulo, A., Allocca, M., Corte, M. D., Rossi, S., Giunti, M., Bacci, M. L., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0022166 · Cited by 60 · see citing works
Efficient gene delivery and selective transduction of astrocytes in the mammalian brain using viral vectors
Merienne, N., Douce, J. L., Faivre, E., Déglon, N., & Bonvento, G. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00106 · Cited by 58 · see citing works
miR-124: A Promising Therapeutic Target for Central Nervous System Injuries and Diseases
Xu, J., Zheng, Y., Wang, L., Liu, Y., Wang, X., Li, Y., & Chi, G. (2022) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-021-01091-6 · Cited by 55 · see citing works
MicroRNA‑124: an emerging therapeutic target in central nervous system disorders
Zhang, W.-H., Jiang, L., Li, M., & Liu, J. (2023) · Experimental Brain Research · doi:10.1007/s00221-022-06524-2 · Cited by 43 · see citing works
miR‐124 Contributes to the functional maturity of microglia
Svahn, A. J., Giacomotto, J., Graeber, M. B., Rinkwitz, S., & Becker, T. S. (2016) · Developmental Neurobiology · doi:10.1002/dneu.22328 · Cited by 42 · see citing works
Immunomodulatory effects of phytosomal curcumin on related‐micro <scp>RNAs</scp>, <scp>CD200</scp> expression and inflammatory pathways in dental pulp stem cells
Ayadilord, M., Nasseri, S., Emadian Razavi, F., Saharkhiz, M., Rostami, Z., & Naseri, M. (2021) · Cell Biochemistry and Function · doi:10.1002/cbf.3659 · Cited by 30 · see citing works
A curated human cellular microRNAome based on 196 primary cell types
Patil, A. H., Baran, A., Brehm, Z. P., McCall, M. N., & Halushka, M. K. (2022) · GigaScience · doi:10.1093/gigascience/giac083 · Cited by 30 · see citing works
MicroRNAs in brain cholesterol metabolism and their implications for Alzheimer's disease
Yoon, H., Flores, L. F., & Kim, J. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2016.04.020 · Cited by 23 · see citing works
Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal lobe epilepsy
Brindley, E., Heiland, M., Mooney, C., Diviney, M., Mamad, O., Hill, T. D. M., Yan, Y., Venø, M. T., Reschke, C. R., Batool, A., et al. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2023.1230942 · Cited by 21 · see citing works
Acute Cerebral Ischemia Increases a Set of Brain-Specific miRNAs in Serum Small Extracellular Vesicles
Zhou, X., Xu, C., Chao, D., Chen, Z., Li, S., Shi, M., Pei, Y., Dai, Y., Ji, J., Ji, Y., et al. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.874903 · Cited by 13 · see citing works
UNC93B1 Is Widely Expressed in the Murine CNS and Is Required for Neuroinflammation and Neuronal Injury Induced by MicroRNA let-7b
Klammer, M. G., Dzaye, O., Wallach, T., Krüger, C., Gaessler, D., Buonfiglioli, A., Derkow, K., Kettenmann, H., Brinkmann, M. M., & Lehnardt, S. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.715774 · Cited by 6 · see citing works

Authors: Lagos-Quintana, M., Rauhut, R., Yalcin, A., Meyer, J., Lendeckel, W., & Tuschl, T.
Venue: Current Biology
Publisher: Elsevier BV
Published: 2002-04
Volume: 12
Issue: 9
Pages: 735-739
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(02)00809-6
Cited by: 2,859
References: 2
Language: en
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 4125 d)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Identification of tissue-specific microRNAs from mouse

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Record

About these checks