Hypocholesterolemic effect of yogurt and milk
Abstract
In order to determine the effect of milk products on serum cholesterol, triglycerides, and diet, 54 volunteers were studied for varying periods with dietary supplementation of nonpasteurized yogurt, pasteurized yogurt and 2% butterfat milk. Serum cholesterol was significantly reduced by 5 to 10% after 1 week of supplementation with either nonpasteurized or pasteurized yogurt; 2% butterfat milk reduced serum cholesterol to a smaller and less significant effect. Serum triglycerides were unaffected by the diet and dietary intake studies confirmed that intake of other nutrients remained relatively stable throughout the study. Supplementation of diet with yogurt may have a helpful hypocholesterolemic effect.
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Several small-scale studies reported lowered cholesterol on using probiotics with bile salt hydrolytic activity.
“Interestingly, several small-scale studies reported lowered cholesterol on using probiotics with bile salt hydrolytic activity.43,44”
From The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood Lipids (2015) · cites this paper as [43]
Cites
Enzymatic determination of total serum cholesterol.
Allain, C. C., Poon, L. S., Chan, C. S. G., Richmond, W., & Fu, P. C. (1974) · Clinical Chemistry · doi:10.1093/clinchem/20.4.470 · Cited by 9,845 · see citing works
Quantitative Determination of Serum Triglycerides by the Use of Enzymes
Bucolo, G., & David, H. (1973) · Clinical Chemistry · doi:10.1093/clinchem/19.5.476 · Cited by 3,202 · see citing works
Serum cholesterol, lipoproteins, and the risk of coronary heart disease. The Framingham study.
Kannel, W., Castelli, W., Gordon, T., & McNamara, P. M. (2020) · Annals of Internal Medicine · doi:10.7326/0003-4819-74-1-1 · Cited by 2,160 · see citing works
THE INFLUENCE OF DIETARY FATS ON SERUM-LIPID LEVELS IN MAN
Ahrens, E., Insull, W., Blomstrand, R., Hirsch, J., Tsaltas, T. T., & Peterson, M. L. (1957) · The Lancet · doi:10.1016/s0140-6736(57)91280-1 · Cited by 726 · see citing works
Effect of citrus pectin on blood lipids and fecal steroid excretion in man
Kay, R. M., & Truswell, A. S. (1977) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/30.2.171 · Cited by 402 · see citing works
Studies of a surfactant and cholesteremia in the Maasai
Mann, G. V., & Spoerry, A. (1974) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/27.5.464 · Cited by 386 · see citing works
Regulation of Cholesterol Metabolism
Dietschy, J. M., & Wilson, J. D. (1970) · New England Journal of Medicine · doi:10.1056/nejm197005142822005 · Cited by 362 · see citing works
SOYBEAN-PROTEIN DIET IN THE TREATMENT OF TYPE-II HYPERLIPOPROTEINÆMIA
Sirtori, C. R., Agradi, E., Conti, F., Mantero, O., & Gatti, E. (1977) · The Lancet · doi:10.1016/s0140-6736(77)91823-2 · Cited by 351 · see citing works
Composition of Foods. Raw, Processed, Prepared
Horavitz, W. (1964) · Journal of AOAC INTERNATIONAL · doi:10.1093/jaoac/47.5.917 · Cited by 338 · see citing works
Carroll, K. K., & Hamilton, R. M. G. (1975) · Journal of Food Science · doi:10.1111/j.1365-2621.1975.tb03726.x · Cited by 306 · see citing works
Regression and Progression of Early Femoral Atherosclerosis in Treated Hyperlipoproteinemic Patients
Barndt, R., BLANKENHORN, D. H., CRAWFORD, D. W., et al. (1977) · Annals of Internal Medicine · doi:10.7326/0003-4819-86-2-139 · Cited by 229 · see citing works
A factor in yogurt which lowers cholesteremia in man
Mann, G. V. (1977) · Atherosclerosis · doi:10.1016/0021-9150(77)90086-7 · Cited by 173 · see citing works
Feeley, R. M., Criner, P. E., & Watt, B. K. (1972) · Journal of the American Dietetic Association · doi:10.1016/s0002-8223(21)15198-3 · Cited by 171 · see citing works
Control of Serum Cholesterol Homeostasis by Cholesterol in the Milk of the Suckling Rat
Reiser, R., & Sidelman, Z. (1972) · Journal of Nutrition · doi:10.1093/jn/102.8.1009 · Cited by 162 · see citing works
SERUM-LIPIDS IN WOMEN ON ORAL CONTRACEPTIVES
Stokes, T., & Wynn, V. (1971) · The Lancet · doi:10.1016/s0140-6736(71)92247-1 · Cited by 127 · see citing works
Effect of weight reduction and caloric balance on serum lipoprotein and cholesterol levels
Walker, W. J., Lawry, E. Y., Love, D. E., et al. (1953) · The American Journal of Medicine · doi:10.1016/0002-9343(53)90383-0 · Cited by 100 · see citing works
The effects of sitosterol on serum lipids
Best, M. M., Duncan, C. H., Loon, E. J. V., et al. (1955) · The American Journal of Medicine · doi:10.1016/0002-9343(55)90274-6 · Cited by 93 · see citing works
Hypocholesterolemic Activity of Mucilaginous Polysaccharides in White Leghorn Cockerels.
Fahrenbach, M. J., Riccardi, B. A., & Grant, W. C. (1966) · Experimental Biology and Medicine · doi:10.3181/00379727-123-31478 · Cited by 75 · see citing works
Effect of Dietary Protein and Fat on Changes of Serum Cholesterol in Mature Birds
Kokatnur, M. G., Rand, N. T., Kummerow, F. A., et al. (1958) · Journal of Nutrition · doi:10.1093/jn/64.2.177 · Cited by 62 · see citing works
Effects of oral calcium upon serum cholesterol and triglycerides in patients with hyperlipidemia
Carlson, L. A., OLSSON, A. G., Orö, L., et al. (1971) · Atherosclerosis · doi:10.1016/0021-9150(71)90067-0 · Cited by 58 · see citing works
LIGNIN: A BILE-SALT SEQUESTRATING AGENT
Eastwood, M. A., & GIRDWOOD, R. H. (1968) · The Lancet · doi:10.1016/s0140-6736(68)91643-7 · Cited by 51 · see citing works
A factor in milk which influences cholesteremia in rats
Nair, C. R., & Mann, G. V. (1977) · Atherosclerosis · doi:10.1016/0021-9150(77)90089-2 · Cited by 49 · see citing works
An Inhibitor of Sterol Biosynthesis present in Cow's Milk
Bogusławski, W., & WRÓBEL, J. (1974) · Nature · doi:10.1038/247210a0 · Cited by 37 · see citing works
A Study of Diet, Blood Lipids and Vascular Disease in Trappist Monks
McCullagh, E. P., & Lewis, L. A. (1960) · New England Journal of Medicine · doi:10.1056/nejm196009222631201 · Cited by 37 · see citing works
The effect of skim milk on plasma cholesterol in rats
MALINOW, M. R., & McLaughlin, P. J. (1975) · Cellular and Molecular Life Sciences · doi:10.1007/bf02326929 · Cited by 33 · see citing works
Plasma lipid changes in young adult couples consuming polyunsaturated meats and dairy products.
Hodges, R. E., Salel, A., Dunkley, W., Zelis, R., McDonagh, P., Clifford, C., Hobbs, R., Smith, L. M., Fan, A., Mason, D. T., et al. (1975) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/28.10.1126 · Cited by 22 · see citing works
Phillppot, J. R., Cooper, A. G., & Wallach, D. F. H. (1976) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(76)80236-7 · Cited by 20 · see citing works
Why bread in the diet lowers serum cholesterol
Groen, J. J. (1973) · Proceedings of The Nutrition Society · doi:10.1079/pns19730034 · Cited by 14 · see citing works
The dictionary of sodium, fats, and cholesterol
Kraus, B. (1974) · Cited by 5 · see citing works
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Bile salt biotransformations by human intestinal bacteria
Ridlon, J. M., Kang, D.-J., & Hylemon, P. B. (2006) · Journal of Lipid Research · doi:10.1194/jlr.r500013-jlr200 · Cited by 2,829 · see citing works
Probiotics and their fermented food products are beneficial for health
Parvez, S., Malik, K. A., Ah Kang, S., & Kim, H.-Y. (2006) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2006.02963.x · Cited by 1,435 · see citing works
The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood Lipids
Fu, J., Bonder, M. J., Cenit, M. C., Tigchelaar, E. F., Maatman, A., Dekens, J. A. M., Brandsma, E., Marczynska, J., Imhann, F., Weersma, R. K., et al. (2015) · Circulation Research · doi:10.1161/circresaha.115.306807 · Cited by 748 · see citing works
Yogurt, cultured fermented milk, and health: A systematic review
Savaiano, D. A., & Hutkins, R. W. (2021) · Nutrition Reviews · doi:10.1093/nutrit/nuaa013 · Cited by 339 · see citing works
Xiao, J. Z., Kondo, S., Takahashi, N., Miyaji, K., Oshida, K., Hiramatsu, A., Iwatsuki, K., Kokubo, S., & Hosono, A. (2003) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(03)73839-9 · Cited by 322 · see citing works
Immunomodulatory and antioxidant potential of <i>Lactobacillus</i> exopolysaccharides
Liu, C., Tseng, K., Chiang, S., Lee, B., Hsu, W., & Pan, T. (2011) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.4456 · Cited by 230 · see citing works
Wang, Y., Xu, N., Xi, A., Ahmed, Z., Zhang, B., & Bai, X. (2009) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-009-2012-x · Cited by 200 · see citing works
St-Onge, M.-P., Farnworth, E. R., Savard, T., Chabot, D., Mafu, A., & Jones, P. J. (2002) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-2-1 · Cited by 167 · see citing works
Anticarcinogenic, hypocholesterolemic, and antagonistic activities of Lactobacillus acidophilus
Mitall, B. K., & Garg, S. K. (1995) · Critical Reviews in Microbiology · doi:10.3109/10408419509113540 · Cited by 97 · see citing works
Influence of Yogurt and Acidophilus Yogurt on Serum Cholesterol Levels in Mice
Sibel Akalin, A., Gönç, S., & Düzel, S. (1997) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(97)76233-7 · Cited by 96 · see citing works
- Authors
- Hepner, G., Fried, R., St Jeor, S., Fusetti, L., & Morin, R.
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 1979-01
- Volume
- 32
- Issue
- 1
- Pages
- 19-24
- ISSN
- 0002-9165 (ISSN-L)
- OpenAlex
- W2112815973
- Cited by
- 202
- References
- 29
- Citations by year
- 2026: 1 · 2025: 4 · 2022: 3 · 2021: 1 · 2020: 2 · 2019: 3 · 2018: 1 · 2017: 6 · 2016: 2 · 2015: 7 · 2014: 8 · 2013: 4 · 2012: 5
- FWCI
- 18.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Life Sciences › Agricultural and Biological Sciences › Food Science › Food and Agricultural Sciences
- Keywords
- yogurt, milk, cholesterol-lowering effect, serum cholesterol, serum triglycerides, dietary supplementation, dietary fat intake
- MeSH terms
- Adult, Animals, Anticholesteremic Agents, Body Weight, Energy Intake, Cholesterol, Dairy Products, Female, Food Microbiology, Hot Temperature, Humans, Male, Middle Aged, Milk, Triglycerides, Yogurt
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