Medium-chain triglycerides: an update
Abstract
A review of the literature on the medical and nutritional use of medium-chain triglycerides (MCTs) since 1970 is presented with additional discussions on the various modifications and applications of the MCTs in the synthesis of certain structured lipids. The metabolism of MCTs in the liver and extrahepatic tissues is discussed along with further documentation of the use of MCTs in malabsorption and hyperlipidemia cases. Recent applications of MCTs and modified MCTs in hyperalimentation, deficiency in the carnitine system, epilepsy, obesity, and other special areas of application are cited. The use of medium-chain monodiglycerides for dissolving cholesterol gallstones is presented. The contraindications for the use of MCTs in ketosis, acidosis, and cirrhosis are also discussed. Suggestions for use of MCTs in a variety of medical and nutritional applications are presented.
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MCT oil is used to increase overall caloric intake and adjust the macronutrient distribution of the diet, helping to prevent excessive percentage of overall caloric intake from carbohydrate sources.
“MCT oil is used to increase overall caloric intake and adjust the macronutrient distribution of the diet, helping to prevent excessive percentage of overall caloric intake from carbohydrate sources.28,29”
From Familial chylomicronemia syndrome: Bringing to life dietary recommendations throughout the life span (2018) · cites this paper as [29]
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- Authors
- Bach, A., & Babayan, V.
- Corresponding author
- Babayan, VK
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 1982-11
- Volume
- 36
- Issue
- 5
- Pages
- 950-962
- ISSN
- 0002-9165 (ISSN-L)
- OpenAlex
- W2109879785
- Cited by
- 1,151
- References
- 104
- Citations by year
- 2026: 29 · 2025: 28 · 2024: 29 · 2023: 28 · 2022: 35 · 2021: 36 · 2020: 44 · 2019: 31 · 2018: 32 · 2017: 28 · 2016: 50 · 2015: 34 · 2014: 30 · 2013: 27 · 2012: 29
- FWCI
- 1.02
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Diet and metabolism studies
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Keywords
- medium-chain triglycerides, structured lipids, malabsorption, hyperlipidemia, hyperalimentation, carnitine deficiency, epilepsy, obesity, ketosis, acidosis, liver cirrhosis, dietary fat
- MeSH terms
- Animals, Anticonvulsants, Carnitine, Celiac Disease, Dietary Fats, Diglycerides, Enteral Nutrition, Fatty Acids, Gallbladder Diseases, Humans, Ketone Bodies, Lipids, Liver, Models, Biological, Parenteral Nutrition, Structure-Activity Relationship, Lipid Metabolism
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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