The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Effects of carotenoids in cellular and animal systems
Open accessAbstract
It has been suggested that carotenoid pigments may function as chemopreventive agents for reducing the risk of cancer in humans. Part of this suggestion rests on epidemiological evidence, and part rests on work done in cellular and animal systems. In this article, the experimental evidence for carotenoid inhibition of mutagenicity, malignant transformation, tumor formation, and immunoenhancement is reviewed. Although a mechanism for these effects cannot yet be identified, it is clear that the overwhelming evidence in these systems would indicate that carotenoids exert an important influence in modulating the actions of carcinogens.
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Citations
Cites
β-Carotene: an Unusual Type of Lipid Antioxidant
Burton, G. W., & Ingold, K. U. (1984) · Science · doi:10.1126/science.6710156 · Cited by 2,150
Regression of experimental hamster cancer by beta carotene and algae extracts
Schwartz, J., & Shklar, G. (1987) · Journal of Oral and Maxillofacial Surgery · doi:10.1016/s0278-2391(87)80011-3 · Cited by 109
Cited by
Vegetables, fruit, and cancer. II. Mechanisms
Steinmetz, K. A., & Potter, J. D. (1991) · Cancer Causes and Control · doi:10.1007/bf00054304 · Cited by 804
[38] Antioxidant effects of carotenoids in Vivo and in Vitro: An overview
Palozza, P., & Krinsky, N. I. (1992) · Methods in Enzymology · doi:10.1016/0076-6879(92)13142-k · Cited by 470
Self-citationIndustrial potential of carotenoid pigments from microalgae: Current trends and future prospects
Ambati, R. R., Gogisetty, D., Aswathanarayana, R. G., Ravi, S., Bikkina, P. N., Bo, L., & Yuepeng, S. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1432561 · Cited by 372
Immune system effects of Echinacea, ginseng, and astragalus: A review
Block, K. I., & Mead, M. N. (2003) · Integrative Cancer Therapies · doi:10.1177/1534735403256419 · Cited by 314
Apoptosis-inducing effect of fucoxanthin on human leukemia cell line HL-60
HOSOKAWA, M., WANEZAKI, S., MIYAUCHI, K., KURIHARA, H., KOHNO, H., KAWABATA, J., ODASHIMA, S., & TAKAHASHI, K. (1999) · Food Science and Technology Research · doi:10.3136/fstr.5.243 · Cited by 173
Metadata
- Authors
- Krinsky, N.
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 1991-01
- Volume
- 53
- Issue
- 1
- Pages
- 238S-246S
- ISSN
- 0002-9165 (ISSN-L)
- OpenAlex
- W2166260158
- Cited by
- 197
- References
- 2
- FWCI
- 10.05
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Krinsky, N. (1991). Effects of carotenoids in cellular and animal systems. The American Journal of Clinical Nutrition. https://doi.org/10.1093/ajcn/53.1.238s
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