The effect of exercise on fructose absorption
Abstract
The effect of exercise on intestinal absorption of fructose was evaluated in 10 subjects after they consumed four beverages, each containing a total of 50 g carbohydrate: 100% fructose (100F), 95% fructose and 5% glucose (95F), 70% fructose and 30% glucose (70F), and 100% glucose (100G), as well as a water placebo. With 100F and 95F, breath hydrogen, which is an index of incomplete absorption, increased significantly in all subjects. In contrast, hydrogen excretion did not increase in any subject after consumption of 100G or water, or in five of seven subjects who consumed 70F. The rapid increase in hydrogen excretion observed when consumption of 100F was followed by exercise was not noted during a comparable nonexercise trial. These data suggest that intestinal capacity for absorption of fructose is readily saturated after ingestion of amounts as small as 50 g and that exercise, which reduces intestinal transit time, can cause incomplete absorption of fructose.
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Ingestion of large amounts of fructose alone causes gastrointestinal distress, and the capacity for intestinal absorption of fructose ingested alone is limited.
“Furthermore, ingestion of large amounts of fructose (alone) has been reported to cause gastrointestinal distress, and the capacity for intestinal absorption of fructose ingested alone has also been shown to be limited (Truswell et al. 1988; Fujisawa et al. 1993).”
From Fructose co‐ingestion to increase carbohydrate availability in athletes (2019) · cites this paper as Fujisawa et al. 1993
Exercise is known to increase absorption of fructose.
“As exercise is known to increase absorption of fructose (Fujisawa et al., 1993)”
From Six-Week Endurance Exercise Alters Gut Metagenome That Is not Reflected in Systemic Metabolism in Over-weight Women (2018) · cites this paper as Fujisawa et al., 1993
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- Authors
- Fujisawa, T., Mulligan, K., Wada, L., Schumacher, L., Riby, J., & Kretchmer, N.
- Affiliations
- Kurume University (JP)
- Corresponding author
- Riby, J
- ORCID
- Mulligan, K
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 1993-07
- Volume
- 58
- Issue
- 1
- Pages
- 75-79
- ISSN
- 0002-9165 (ISSN-L)
- OpenAlex
- W1855977187
- Cited by
- 42
- References
- 22
- Citations by year
- 2026: 1 · 2023: 1 · 2022: 1 · 2021: 2 · 2019: 3 · 2018: 1 · 2017: 2 · 2016: 1 · 2015: 2 · 2014: 2 · 2013: 3
- FWCI
- 0.30
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5t32hd007266-10, 5p30hd022224-02)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD22224, HD 07266)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
- Keywords
- fructose absorption, physical activity, intestinal transit time, breath hydrogen, carbohydrate digestion
- MeSH terms
- Physical Exertion, Fructose, Glucose, Humans, Hydrogen, Intestinal Absorption, Placebos
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