Cited by 3,204Vitamin D Research StudiesParathyroid Disorders and TreatmentsVitamin K Research Studies

The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

Decreased bioavailability of vitamin D in obesity

Open access

Wortsman, Jacobo, Matsuoka, Lois Y, Chen, Tai C, Lu, Zhiren, Holick, Michael F·2000·The American Journal of Clinical Nutrition

DOI 10.1093/ajcn/72.3.690

Open this paper in CoChat — free account

Abstract

Background Obesity is associated with vitamin D insufficiency and secondary hyperparathyroidism.Objective This study assessed whether obesity alters the cutaneous production of vitamin D(3) (cholecalciferol) or the intestinal absorption of vitamin D(2) (ergocalciferol).Design Healthy, white, obese [body mass index (BMI; in kg/m(2)) > or = 30] and matched lean control subjects (BMI </= 25) received either whole-body ultraviolet radiation or a pharmacologic dose of vitamin D(2) orally.Results Obese subjects had significantly lower basal 25-hydroxyvitamin D concentrations and higher parathyroid hormone concentrations than did age-matched control subjects. Evaluation of blood vitamin D(3) concentrations 24 h after whole-body irradiation showed that the incremental increase in vitamin D(3) was 57% lower in obese than in nonobese subjects. The content of the vitamin D(3) precursor 7-dehydrocholesterol in the skin of obese and nonobese subjects did not differ significantly between groups nor did its conversion to previtamin D(3) after irradiation in vitro. The obese and nonobese subjects received an oral dose of 50000 IU (1.25 mg) vitamin D(2). BMI was inversely correlated with serum vitamin D(3) concentrations after irradiation (r = -0.55, P: = 0.003) and with peak serum vitamin D(2) concentrations after vitamin D(2) intake (r = -0.56, P: = 0.007).Conclusions Obesity-associated vitamin D insufficiency is likely due to the decreased bioavailability of vitamin D(3) from cutaneous and dietary sources because of its deposition in body fat compartments.

Integrity signals

Registry

Crossref · 10.1093/ajcn/72.3.690

Cites

19 of 19 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Experimental Design: Procedures for the Behavioral Sciences
Kirk, R. (2013) · doi:10.4135/9781483384733 · Cited by 8,539
Aging decreases the capacity of human skin to produce vitamin D3.
MacLaughlin, J. A., & Holick, M. F. (1985) · Journal of Clinical Investigation · doi:10.1172/jci112134 · Cited by 1,442
Self-citation
Experimental design: Procedures for the behavioral sciences (3rd ed.).
Kirk, R. E. (1995) · Cited by 787
Photosynthesis of Previtamin D 3 in Human Skin and the Physiologic Consequences
Holick, M. F., MacLaughlin, J. A., Clark, M. B., Holick, S. A., Potts, J. T. J., Anderson, R. R., Blank, I. H., Parrish, J. A., & Elias, P. M. (1980) · Science · doi:10.1126/science.6251551 · Cited by 778
Self-citation
Evidence for alteration of the vitamin D-endocrine system in obese subjects.
Bell, N. H., Epstein, S., Greene, A. S., Shary, J., Oexmann, M. J., & Shaw, S. (1985) · Journal of Clinical Investigation · doi:10.1172/jci111971 · Cited by 685
Sunscreens Suppress Cutaneous Vitamin D3Synthesis*
Matsuoka, L. Y., IDE, L., Wortsman, J., MacLaughlin, J. A., & Holick, M. F. (1987) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-64-6-1165 · Cited by 600
Self-citation
Low circulating vitamin D in obesity
Liel, Y., Ulmer, E., Shary, J., Hollis, B. W., & Bell, N. H. (1988) · Calcified Tissue International · doi:10.1007/bf02555135 · Cited by 388
Racial Pigmentation and the Cutaneous Synthesis of Vitamin D
Matsuoka, L. Y. (1991) · Archives of Dermatology · doi:10.1001/archderm.1991.04510010104011 · Cited by 302
Self-citation
Effects of skin thickness, age, body fat, and sunlight on serum 25-hydroxyvitamin D
Need, A. G., Morris, H., Horowitz, M., & Nordin, C. (1993) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/58.6.882 · Cited by 301
Vitamin D status and bone histomorphometry in gross obesity
Compston, J. E., Vedi, S., Ledger, J. E., Webb, A., Gazet, J. C., & Pilkington, T. R. (1981) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/34.11.2359 · Cited by 249

Flagged first, then by citations

Show all 19 references

Sorted by citations

Items 901–1,000 of 1,005

Seasonal Variation of Slipped Capital Femoral Epiphysis in the United States
Brown, D. (2004) · Journal of Pediatric Orthopaedics · doi:10.1097/00004694-200403000-00001 · Cited by 43
Body Mass Index in the Evaluation of Thyroid Cancer Risk
Mijović, T., How, J., Pakdaman, M. N., Rochon, L., Gologan, O., Hier, M. P., Black, M. J., Young, J., Tamilia, M., & Payne, R. J. (2009) · Thyroid · doi:10.1089/thy.2008.0386 · Cited by 42
Vitamin D Status and Its Relationship with Body Composition, Bone Mineral Density and Fracture Risk in Urban Central South Chinese Postmenopausal Women
Li, S., Ou, Y., Zhang, H., Zhang, Z., Zhou, H., Liu, L., Sheng, Z., & Liao, E. (2014) · Annals of Nutrition and Metabolism · doi:10.1159/000358340 · Cited by 42
A role of vitamin D in low-intensity chronic inflammation and insulin resistance in type 2 diabetes mellitus?
Flores, M. (2005) · Nutrition Research Reviews · doi:10.1079/nrr2005104 · Cited by 42
A review of Vitamin D effects on common respiratory diseases: Asthma, chronic obstructive pulmonary disease, and tuberculosis
Entezari‐Maleki, T., Hejazi, M., & Modarresi‐Ghazani, F. (2016) · Journal of Research in Pharmacy Practice · doi:10.4103/2279-042x.176542 · Cited by 42
Maternal BMI Associations with Maternal and Cord Blood Vitamin D Levels in a North American Subset of Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study Participants
Josefson, J. L., Reisetter, A. C., Scholtens, D. M., Price, H. E., Metzger, B. E., & Langman, C. B. (2016) · PLoS ONE · doi:10.1371/journal.pone.0150221 · Cited by 42
Prepubertal Adiposity, Vitamin D Status, and Insulin Resistance
Cediel, G., Corvalán, C., de Romaña, D. L., Verónica Mericq, G., & Uauy, R. D. (2016) · PEDIATRICS · doi:10.1542/peds.2016-0076 · Cited by 42
Impact of obesity on bone metabolism
Gómez, J. J. L., Castrillón, J. L. P., & de Luis, D. A. (2016) · Endocrinología y Nutrición (English Edition) · doi:10.1016/j.endoen.2016.08.013 · Cited by 42
Vitamin D, Gestational Diabetes, and Measures of Glucose Metabolism in a Population-Based Multiethnic Cohort
Eggemoen, Å. R., Waage, C. W., Sletner, L., Gulseth, H. L., Birkeland, K. I., & Jenum, A. K. (2018) · Journal of Diabetes Research · doi:10.1155/2018/8939235 · Cited by 43
The Effect of Vitamin D Supplementation on Insulin Sensitivity: A Systematic Review and Meta-analysis
Pramono, A., Jocken, J. W. E., Blaak, E. E., & van Baak, M. A. (2020) · Diabetes Care · doi:10.2337/dc19-2265 · Cited by 43
Relationship of Vitamin D status with testosterone levels: a systematic review and meta-analysis
D’Andrea, S., Martorella, A., Coccia, F., Castellini, C., Minaldi, E., Totaro, M., Parisi, A., Francavilla, F., Francavilla, S., & Barbonetti, A. (2020) · Endocrine · doi:10.1007/s12020-020-02482-3 · Cited by 43
Associations of Serum 25-Hydroxyvitamin D3 Levels with Visceral Adipose Tissue in Chinese Men with Normal Glucose Tolerance
Hao, Y., Ma, X., Shen, Y., Ni, J., Luo, Y., Xiao, Y., Bao, Y., & Jia, W. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086773 · Cited by 42
Vitamin D metabolites and bone mineral density: The multi-ethnic study of atherosclerosis
van Ballegooijen, A. J., Robinson‐Cohen, C., Katz, R., Criqui, M. H., Budoff, M. J., Li, D., Siscovick, D. S., Hoofnagle, A. N., Shea, S., Burke, G. L., et al. (2015) · Bone · doi:10.1016/j.bone.2015.05.008 · Cited by 41
Bariatric surgery and bone metabolism: a systematic review
Viégas, M., de Vasconcelos, R. S., Neves, A. P., Diniz, E. T., & Bandeira, F. A. F. (2010) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302010000200011 · Cited by 41
Vitamin D in pregnancy at high latitude in Scotland
Haggarty, P., Campbell, D. M., Knox, S., Horgan, G. W., Hoad, G., Boulton, E., McNeill, G., & Wallace, A. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512002255 · Cited by 43
25‐hydroxyvitamin D accumulation during summer in elderly women at latitude 60ºN
Burgaz, A., Åkesson, A., Michaëlsson, K., & Wolk, A. (2009) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2009.02125.x · Cited by 41
Lean mass appears to be more strongly associated with bone health than fat mass in urban black South African women
Sotunde, O. F., Kruger, H. S., Wright, H. H., Havemann‐Nel, L., Kruger, I. M., Wentzel‐Viljoen, E., Kruger, A., & Tieland, M. (2015) · The journal of nutrition health & aging · doi:10.1007/s12603-015-0492-1 · Cited by 43
The High Serum Monocyte Chemoattractant Protein-1 in Obesity Is Influenced by High Parathyroid Hormone and Not Adiposity
Sukumar, D., Partridge, N. C., Wang, X., & Shapses, S. A. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-2781 · Cited by 41
Hormonal and dietary influences on true fractional calcium absorption in women: role of obesity
Shapses, S. A., Sukumar, D., Schneider, S. H., Schlussel, Y., Brolin, R. E., & Taich, L. (2012) · Osteoporosis International · doi:10.1007/s00198-012-1901-5 · Cited by 41
Energy Restriction Is Associated with Lower Bone Mineral Density of the Tibia and Femur in Lean but Not Obese Female Rats
Hawkins, J., Cifuentes, M., Pleshko, N. L., Ambia‐Sobhan, H., & Shapses, S. A. (2009) · Journal of Nutrition · doi:10.3945/jn.109.111450 · Cited by 41
Slipped capital femoral epiphysis associated with vitamin D deficiency
Madhuri, V., Arora, S. K., & Dutt, V. (2013) · The Bone & Joint Journal · doi:10.1302/0301-620x.95b6.30806 · Cited by 41
Vitamin D Concentrations and Obstructive Sleep Apnea in a Multicenter Cohort of Older Males
Goswami, U., Ensrud, K. E., Paudel, M. L., Redline, S. S., Schernhammer, E. S., Shikany, J. M., Stone, K. L., & Kunisaki, K. M. (2016) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201507-440oc · Cited by 41
Vitamin D and serum leptin: a systematic review and meta-analysis of observational studies and randomized controlled trials
Hajimohammadi, M., Shab‐Bidar, S., & Neyestani, T. R. (2016) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2016.245 · Cited by 42
Sustainable Nutrition in a Changing World
Biesalski, H. K., Drewnowski, A., Dwyer, J. T., Strain, J., Weber, P., & Eggersdorfer, M. L. (2017) · Springer eBooks · doi:10.1007/978-3-319-55942-1 · Cited by 41
Role of Vitamin D in Rheumatoid Arthritis
Bellan, M., Sainaghi, P. P., & Pirisi, M. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-56017-5_13 · Cited by 43
Evidence of an Association Between Vitamin D Deficiency and Preterm Birth and Preeclampsia: A Critical Review
Woo, J., Giurgescu, C., & Wagner, C. L. (2019) · Journal of Midwifery & Women s Health · doi:10.1111/jmwh.13014 · Cited by 42
Vitamin D Deficiency and Insufficiency in Hospitalized COPD Patients
Mekov, E., Slavova, Y. G., Tsakova, A. D., Genova, M. P., Kostadinov, D., Minchev, D., Marinova, D., & Tafradjiiska, M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0129080 · Cited by 41
Season of birth and prevalence of overweight and obesity in Canada
Wattie, N., Ardern, C. I., & Baker, J. R. (2008) · Early Human Development · doi:10.1016/j.earlhumdev.2007.12.010 · Cited by 40
Mineral Metabolism in Obese Patients Following Vertical Banded Gastroplasty
Olmos, J. M., Vázquez, L. A., Amado, J., Hernández, J. L., & Macías, J. G. (2008) · Obesity Surgery · doi:10.1007/s11695-007-9307-8 · Cited by 41
Preoperative micronutrient status in morbidly obese patients before undergoing bariatric surgery: results of a cross-sectional study
Wolf, E., Utech, M., Stehle, P., Büsing, M., Stoffel‐Wagner, B., & Ellinger, S. (2015) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2015.03.018 · Cited by 41
Parathyroid hormone and bone marker levels in patients with morbid obesity before and after biliopancreatic diversion
Moreiro, J., Ruiz, O., Perez, G., Salinas, R., Urgeles, J. R., Riesco, M., & García-Sanz, M. (2007) · Obesity Surgery · doi:10.1007/s11695-007-9063-9 · Cited by 40
Physiology of Calcium, Phosphate and Magnesium
Allgrove, J. (2009) · Endocrine development · doi:10.1159/000223685 · Cited by 40
Vitamin D levels appear to be normal in Danish patients attending secondary care for low back pain and a weak positive correlation between serum level Vitamin D and Modic changes was demonstrated: a cross-sectional cohort study of consecutive patients with non-specific low back pain
Johansen, J. V., Manniche, C., & Kjær, P. (2013) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-14-78 · Cited by 45
Metabolic Management following Bariatric Surgery
Strohmayer, E., Via, M. A., & Yanagisawa, R. T. (2010) · Mount Sinai Journal of Medicine A Journal of Translational and Personalized Medicine · doi:10.1002/msj.20211 · Cited by 41
A parallel group double-blind RCT of vitamin D3 assessing physical function: is the biochemical response to treatment affected by overweight and obesity?
Wood, A. D., Secombes, K. R., Thiès, F., Aucott, L. S., Black, A. J., Reid, D. M., Mavroeidi, A., Simpson, W. G., Fraser, W. D., & Macdonald, H. M. (2013) · Osteoporosis International · doi:10.1007/s00198-013-2473-8 · Cited by 41
Hypovitaminosis D and Mild Hypocalcaemia Are Highly Prevalent among Young Vietnamese Children and Women and Related to Low Dietary Intake
Laillou, A., Wieringa, F. T., Tran, T. N., Van, P. T., Le, B. M., Fortin, S., Le, T. H., Moench‐Pfanner, R., & Berger, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0063979 · Cited by 41
Higher bone mineral density in Caucasian, hirsute patients of reproductive age. Positive correlation of testosterone levels with bone mineral density in hirsutism
Glintborg, D., Andersen, M., Hagen, C., & Hermann, A. P. (2005) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2005.02280.x · Cited by 40
Influence of age and gender on associations of body mass index with bone mineral density, bone turnover markers and circulating calcium-regulating and bone-active sex hormones
Puntus, T., Schneider, B., Meran, J. G., Peterlik, M., & Kudlacek, S. (2011) · Bone · doi:10.1016/j.bone.2011.06.003 · Cited by 40
Determinants of 25-hydroxyvitamin D levels in African-American and Caucasian male veterans
Benjamin, A., Moriakova, A., Akhter, N., Rao, D., Xie, H. W., Kukreja, S. C., & Barengolts, E. I. (2009) · Osteoporosis International · doi:10.1007/s00198-009-0873-6 · Cited by 40
25-Hydroxyvitamin D: Analysis and clinical application
Su, Z., Narla, S. N., & Zhu, Y. (2014) · Clinica Chimica Acta · doi:10.1016/j.cca.2014.03.022 · Cited by 40
Is vitamin D status relevant to metabolic syndrome?
Boucher, B. J. (2012) · Dermato-Endocrinology · doi:10.4161/derm.20012 · Cited by 40
Dairy calcium supplementation in overweight or obese persons: its effect on markers of fat metabolism
Bortolotti, M., Rudelle, S., Schneiter, P., Vidal, H., Loizon, E., Tappy, L., & Acheson, K. J. (2008) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/88.4.877 · Cited by 40
Serum 25-hydroxyvitamin D3 and body composition in an elderly cohort from Germany: a cross-sectional study
Jungert, A., Roth, H. J., & Neuhäuser‐Berthold, M. (2012) · Nutrition & Metabolism · doi:10.1186/1743-7075-9-42 · Cited by 40
Vitamin D and Dysfunctional Adipose Tissue in Obesity
Stokić, E., Kupusinac, A., Tomić-Naglić, D., Smiljenić, D., Kovačev-Zavišić, B., Srdić, B., Šoškić, S., & Isenović, E. R. (2014) · Angiology · doi:10.1177/0003319714543512 · Cited by 41
Analysis of Vitamin D Status in Major Depression
Józefowicz, O., Rabe‐Jabłońska, J., Woźniacka, A. J., & Strzelecki, D. (2014) · Journal of Psychiatric Practice · doi:10.1097/01.pra.0000454777.21810.15 · Cited by 40
Ultraviolet radiation, vitamin D and the development of obesity, metabolic syndrome and type-2 diabetes
Gorman, S., Lucas, R. M., Aidan, A.-H., Fleury, N., & Feelisch, M. (2016) · Photochemical & Photobiological Sciences · doi:10.1039/c6pp00274a · Cited by 41
Serum vitamin D and change in lipid levels over 5 y: The Atherosclerosis Risk in Communities study
Faridi, K. F., Zhao, D., Martin, S. S., Lupton, J. R., Jones, S. R., Güallar, E., Ballantyne, C. M., Lutsey, P. L., & Michos, E. D. (2017) · Nutrition · doi:10.1016/j.nut.2017.01.008 · Cited by 41
Influence of Various Factors on Circulating 25(OH) Vitamin D Concentrations in Dogs with Cancer and Healthy Dogs
Weidner, N., Woods, J. P., Conlon, P. D., Meckling, K. A., Atkinson, J., Bayle, J., Makowski, A. J., Horst, R. L., & Verbrugghe, A. (2017) · Journal of Veterinary Internal Medicine · doi:10.1111/jvim.14834 · Cited by 40
The effect of vitamin D supplementation in combination with low-calorie diet on anthropometric indices and androgen hormones in women with polycystic ovary syndrome: a double-blind, randomized, placebo-controlled trial
Jafari-Sfidvajani, S. J., Ahangari, R., Hozoori, M., Mozaffari–Khosravi, H., Fallahzadeh, H., & Nadjarzadeh, A. (2017) · Journal of Endocrinological Investigation · doi:10.1007/s40618-017-0785-9 · Cited by 43
Vitamin D Deficiency and Association With Body Mass Index and Lipid Levels in Hispanic American Adolescents
Kumaratne, M., Early, G. J., & Cisneros, J. (2017) · Global Pediatric Health · doi:10.1177/2333794x17744141 · Cited by 40
Association of Vitamin D Metabolites With Embryo Development and Fertilization in Women With and Without PCOS Undergoing Subfertility Treatment
Cunningham, T. K., Allgar, V. L., Dargham, S. R., Kilpatrick, E. S., Sathyapalan, T., Maguiness, S. D., Rudin, H. R. M., Ghani, N. M. A., Latiff, A. A., & Atkin, S. L. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00013 · Cited by 40
Multiple Sclerosis: Lipids, Lymphocytes, and Vitamin D
Hayes, C. E., & Ntambi, J. M. (2020) · Immunometabolism · doi:10.20900/immunometab20200019 · Cited by 41
Vitamin D 3 supplementation does not enhance the effects of resistance training in older adults
Mølmen, K. S., Hammarström, D., Pedersen, K. K., Lie, A. C. L., Steile, R. B., Nygaard, H., Khan, Y., Hamarsland, H., Koll, L., Hanestadhaugen, M., et al. (2021) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12688 · Cited by 40
Vitamin D status and common risk factors for bone fragility as determinants of quantitative ultrasound variables in a nationally representative population sample
Kauppi, M., Impivaara, O., Mäki, J., Heliövaara, M., Marniemi, J., Montonen, J., & Jula, A. (2009) · Bone · doi:10.1016/j.bone.2009.03.659 · Cited by 40
Vitamin D deficiency and hyperparathyroidism in relation to ethnicity: a cross-sectional survey in healthy adults
Moreno‐Reyes, R., Carpentier, Y., Boelaert, M., Moumni, K. E., Dufourny, G., Bazelmans, C., Lévêque, A., Gervy, C., & Goldman, S. (2008) · European Journal of Nutrition · doi:10.1007/s00394-008-0756-1 · Cited by 40
Vitamin D Status in Malaysian Men and Its Associated Factors
Chin, K., Ima-Nirwana, S., Ibrahim, S., Mohamed, I. N., & Ngah, W. W. (2014) · Nutrients · doi:10.3390/nu6125419 · Cited by 40
Vitamin D insufficiency and chronic diseases: Hype and reality
Peterlik, M. (2012) · Food & Function · doi:10.1039/c2fo10262e · Cited by 41
Circulating 25-Hydroxyvitamin D and Risk of Endometrial Cancer: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers
Zeleniuch‐Jacquotte, A., Gallicchio, L. M., Hartmuller, V. W., Helzlsouer, K. J., McCullough, M. L., Setiawan, V. W., Shu, X., Weinstein, S. J., Weiss, J. M., Arslan, A. A., et al. (2010) · American Journal of Epidemiology · doi:10.1093/aje/kwq114 · Cited by 40
Are low ultraviolet B and high animal protein intake associated with risk of renal cancer?
Mohr, S. B., Gorham, E. D., Garland, C. F., Grant, W. B., & Garland, F. C. (2006) · International Journal of Cancer · doi:10.1002/ijc.22213 · Cited by 40
Associations between vitamin D levels and polycystic ovary syndrome phenotypes
Davis, E. M., Peck, J. D., Hansen, K. R., Neas, B. R., & Craig, L. B. (2019) · Minerva Endocrinologica · doi:10.23736/s0391-1977.18.02824-9 · Cited by 39
Does Vitamin D play a role in the management of Covid-19 in Brazil?
Ribeiro, H., de Santana, K. V. D. S., Oliver, S. L., Rondó, P. H. D. C., Mendes, M. M., Charlton, K. E., & Lanham-New, S. A. (2020) · Revista de Saúde Pública · doi:10.11606/s1518-8787.2020054002545 · Cited by 39
Vitamin D and Covid‐19: From potential therapeutic effects to unanswered questions
Teymoori‐Rad, M., & Marashi, S. M. (2020) · Reviews in Medical Virology · doi:10.1002/rmv.2159 · Cited by 39
Vitamin D and malabsorptive gastrointestinal conditions: A bidirectional relationship?
Giustina, A., di Filippo, L., Allora, A., Bikle, D. D., Cavestro, G. M., Feldman, D., Latella, G., Minisola, S., Napoli, N., Trasciatti, S., et al. (2023) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-023-09792-7 · Cited by 39
Bariatric Nutrition Guidelines for the Indian Population
Remedios, C., Bhasker, A. G., Dhulla, N., Dhar, S., & Lakdawala, M. A. (2015) · Obesity Surgery · doi:10.1007/s11695-015-1836-y · Cited by 39
Predictors of vitamin D biochemical status in a large sample of middle-aged male smokers in Finland
Brock, K. E., Graubard, B. I., Fraser, D. R., Weinstein, S. J., Stolzenberg-Solomon, R. Z., Lim, U., Tangrea, J. A., Virtamo, J. R. K., Ke, L., SNYDER, K. D., et al. (2010) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2009.137 · Cited by 39
Race, vitamin D–binding protein gene polymorphisms, 25-hydroxyvitamin D, and incident diabetes: the Atherosclerosis Risk in Communities (ARIC) Study
Reis, J. P., Michos, E. D., Selvin, E., Pankow, J. S., & Lutsey, P. L. (2015) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.115.107334 · Cited by 38
25-Hydroxyvitamin D in the Range of 20 to 100 ng/mL and Incidence of Kidney Stones
Nguyen, S., Baggerly, L. L., French, C., Heaney, R. P., Gorham, E. D., & Garland, C. F. (2013) · American Journal of Public Health · doi:10.2105/ajph.2013.301368 · Cited by 39
Obesity in the Context of Aging: Quality of Life Considerations
Corica, F., Bianchi, G. P., Corsonello, A., Mazzella, N., Lattanzio, F., & Marchesini, G. (2014) · PharmacoEconomics · doi:10.1007/s40273-014-0237-8 · Cited by 39
Treatment of hypovitaminosis D with pharmacologic doses of cholecalciferol, oral vs intramuscular; an open labeled RCT
Zabihiyeganeh, M., Jahed, S. A., & Nojomi, M. (2012) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2012.04518.x · Cited by 39
Prevalence of Vitamin D deficiency in the North-West region of Russia: A cross-sectional study
Каронова, Т. Л., Тимуровна, А. А., Nikitina, I. L., Belyaeva, О. D., Мохова, Е. В., Галкина, О. В., Vasilyeva, E. Y., & Grineva, E. N. (2016) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2016.03.026 · Cited by 39
Hyperparathyroidism and Vitamin D Deficiency after Laparoscopic Gastric Bypass
Clements, R. H., Yellumahanthi, K., Wesley, M. M., Ballem, N., & Bland, K. I. (2008) · The American Surgeon · doi:10.1177/000313480807400603 · Cited by 39
Vitamin D Deficiency in Patients Referred for Evaluation of Obstructive Sleep Apnea
Salepçi, B. M., Caglayan, B. N., Nahid, P., Parmaksız, E. T., Kıral, N., Fidan, A., Cömert, S. Ş., Doğan, C., & Güngör, G. A. (2017) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.6554 · Cited by 39
Vitamin D predictors in polycystic ovary syndrome: a meta-analysis
Bacopoulou, F., Kolias, E., Efthymiou, V., Antonopoulos, C. N., & Charmandari, E. (2017) · European Journal of Clinical Investigation · doi:10.1111/eci.12800 · Cited by 40
Effects of chronic endurance exercise training on serum 25(OH)D concentrations in elderly Japanese men
Sun, X., Cao, Z., Tanisawa, K., Taniguchi, H., Kubo, T., & Higuchi, M. (2017) · Endocrine · doi:10.1007/s12020-017-1478-z · Cited by 39
Body mass index represents a good predictor of vitamin D status in women independently from age
Monache, S. D., Fulvio, P. D., Iannetti, E., Valerii, L., Capone, L., Nespoli, M., Bologna, M., & Angelucci, A. (2018) · Clinical Nutrition · doi:10.1016/j.clnu.2018.02.024 · Cited by 40
Prevalence of vitamin D deficiency and its predictors in the Portuguese population: a nationwide population-based study
Duarte, C. C. M., Carvalheiro, H., Rodrigues, A. M., Dias, S. S., Marques, A., Santiago, T., Canhão, H. M., Branco, J., & da Silva, J. A. P. (2020) · Archives of Osteoporosis · doi:10.1007/s11657-020-0695-x · Cited by 39
Current and Future Treatments in the Fight against Non-Alcoholic Fatty Liver Disease
Smeuninx, B., Boslem, E., & Febbraio, M. A. (2020) · Cancers · doi:10.3390/cancers12071714 · Cited by 39
Obesity and the increased risk for COVID-19: mechanisms and nutritional management
Morais, A. H. D. A., Passos, T. S., Vale, S. H. D. L., da Silva-Maia, J. K., & Maciel, B. L. L. (2020) · Nutrition Research Reviews · doi:10.1017/s095442242000027x · Cited by 40
Vitamin D and adolescents: what do we know?
Stoffman, N., & Gordon, C. M. (2009) · Current Opinion in Pediatrics · doi:10.1097/mop.0b013e32832da096 · Cited by 39
Seasonal Variation in the Deficiency of 25-Hydroxyvitamin D3 in Mildly to Extremely Obese Subjects.
Ernst, B., Thurnheer, M., Schmid, S. M., Wilms, B., & Schultes, B. (2008) · Obesity Surgery · doi:10.1007/s11695-008-9636-2 · Cited by 39
Vitamin D insufficiency in obese children and relation with lipid profile
Rusconi, R. E., Cosmi, V. D., Ghilardi, G., Giavoli, C., & Agostoni, C. V. (2015) · International Journal of Food Sciences and Nutrition · doi:10.3109/09637486.2014.959902 · Cited by 39
Interaction of body mass index and attempt to lose weight in a national sample of US adults: association with reported food and nutrient intake, and biomarkers
Kant, A. K. (2003) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1601549 · Cited by 38
Dietary Calcium and Vitamin D Intake in an Adult Middle Eastern Population: Food Sources and Relation to Lifestyle and PTH
Gannagé‐Yared, M., Chemali, Sfeir, Maalouf, & Halaby (2005) · International Journal for Vitamin and Nutrition Research · doi:10.1024/0300-9831.75.4.281 · Cited by 39
Vitamin D deficiency: new perspectives on an old disease
Hickey, L., & Gordon, C. M. (2004) · Current Opinion in Endocrinology & Diabetes · doi:10.1097/00060793-200402000-00006 · Cited by 39
Vitamin D deficiency and female infertility: A mechanism review examining the role of vitamin D in ovulatory dysfunction as a symptom of polycystic ovary syndrome
Berry, S., Seidler, K., & Neil, J. (2022) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2022.103633 · Cited by 38
Vitamin D and Visceral Obesity in Humans: What Should Clinicians Know?
Shantavasinkul, P. C., & Nimitphong, H. (2022) · Nutrients · doi:10.3390/nu14153075 · Cited by 40
Determinants of Vitamin D Status among Overweight and Obese Puerto Rican Adults
Palacios, C. S., Gil, K., Pérez, C. M., & JOSHIPURA, K. J. (2012) · Annals of Nutrition and Metabolism · doi:10.1159/000335282 · Cited by 38
Vitamin D status and supplementation in morbid obesity before and after bariatric surgery
Bacci, V., & Silecchia, G. (2010) · Expert Review of Gastroenterology & Hepatology · doi:10.1586/egh.10.69 · Cited by 38
Obesity and cancer: the role of vitamin D
Shanmugalingam, T., Crawley, D., Bosco, C., Melvin, J. C., Rohrmann, S., Chowdhury, S., Holmberg, L., & Hemelrijck, M. V. (2014) · BMC Cancer · doi:10.1186/1471-2407-14-712 · Cited by 40
The effects of calcitriol on improvement of insulin resistance, ovulation and comparison with metformin therapy in PCOS patients: a randomized placebo- controlled clinical trial.
Bonakdaran, S., Khorasani, Z. M., Davachi, B., & khorasani, J. M. (2012) · Europe PMC (PubMed Central) · Cited by 38
Pre-pregnancy obesity and maternal nutritional biomarker status during pregnancy: a factor analysis
Tomedi, L. E., Chang, C.-C. H., Newby, P. K., Evans, R. G., Luther, J. F., Wisner, K. L., & Bodnar, L. M. (2013) · Public Health Nutrition · doi:10.1017/s1368980013000736 · Cited by 38
Three doses of vitamin D, bone mineral density, and geometry in older women during modest weight control in a 1-year randomized controlled trial
Pop, L. C., Sukumar, D., Schneider, S. H., Schlussel, Y., Stahl, T. J., Gordon, C. L., Wang, X., Papathomas, T. V., & Shapses, S. A. (2016) · Osteoporosis International · doi:10.1007/s00198-016-3735-z · Cited by 38
The Effects of Bariatric Surgery on Bone Metabolism
Gregory, N. S. (2016) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2016.09.011 · Cited by 38
Fibroblast Growth Factor 23, Mineral Metabolism, and Adiposity in Normal Kidney Function
Zaheer, S., de Boer, I. H., Allison, M., Brown, J. M., Psaty, B. M., Robinson‐Cohen, C., Michos, E. D., Ix, J. H., Kestenbaum, B. R., Siscovick, D. S., et al. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-3563 · Cited by 38
Impact of Three Doses of Vitamin D3 on Serum 25(OH)D Deficiency and Insufficiency in At-Risk Schoolchildren
Sacheck, J. M., Rompay, M. I. V., Chomitz, V. R., Economos, C. D., Eliasziw, M., Goodman, E., Gordon, C. M., & Holick, M. F. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-01179 · Cited by 38
Self-citation
Prevalence of Micronutrient Deficiencies Prior to Bariatric Surgery: Tehran Obesity Treatment Study (TOTS)
Asghari, G., Khalaj, A., Ghadimi, M., Mahdavi, M., Farhadnejad, H., Valizadeh, M., Azizi, F., Barzin, M., & Hosseinpanah, F. (2018) · Obesity Surgery · doi:10.1007/s11695-018-3187-y · Cited by 39
Bipolar disorder in youth is associated with increased levels of vitamin D-binding protein
Petrov, B., Aldoori, A., James, C. L., Yang, K., Algorta, G. P., Lee, A., Zhang, L., Lin, T., Awadhi, R. A., Parquette, J. R., et al. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0109-7 · Cited by 41
The Impact of Obesity on the Association between Vitamin D Deficiency and Cardiovascular Disease
Paschou, S. Α., Kosmopoulos, M., Nikas, I. P., Spartalis, Μ., Kassi, E., Goulis, D. G., Lambrinoudaki, I. V., & Siasos, G. (2019) · Nutrients · doi:10.3390/nu11102458 · Cited by 40
The role of holistic nutritional properties of diets in the assessment of food system and dietary sustainability
Dave, L. A., Hodgkinson, S. M., Roy, N. C., Smith, N. W., & McNabb, W. C. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.2012753 · Cited by 47
THE GLOBAL EPIDEMIOLOGY OF VITAMIN D STATUS
Edwards, M., Cole, Z. A., Harvey, N. C., & Cooper, C. C. (2014) · Journal of Aging Research and Lifestyle · doi:10.14283/jarcp.2014.26 · Cited by 39

Authors: Wortsman, J., Matsuoka, L. Y., Chen, T. C., Lu, Z., & Holick, M. F.
Affiliations: SIU Medicine (US)
ORCID: Chen, Tai C
Holick, Michael F
Venue: The American Journal of Clinical Nutrition
Publisher: Elsevier BV
Published: 2000-09
Volume: 72
Issue: 3
Pages: 690-693
ISSN: 0002-9165 (ISSN-L)
DOI: 10.1093/ajcn/72.3.690
OpenAlex: W2157304718
Cited by: 3,204
References: 19
Citations by year: 2026: 73 · 2025: 89 · 2024: 97 · 2023: 138 · 2022: 190 · 2021: 173 · 2020: 177 · 2019: 158 · 2018: 183 · 2017: 194 · 2016: 189 · 2015: 213 · 2014: 215 · 2013: 231 · 2012: 193
FWCI: 5.20
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 8214 d)
Locations: American Journal of Clinical Nutrition (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Arthritis and Musculoskeletal and Skin Diseases (AR369637)
National Center for Research Resources (MO1 RR 00533, M01RR000533)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Vitamin D Research Studies
Health Sciences › Medicine › Nephrology › Parathyroid Disorders and Treatments
Health Sciences › Nursing › Nutrition and Dietetics › Vitamin K Research Studies
Keywords: obesity, vitamin D bioavailability, vitamin D insufficiency, 25-hydroxyvitamin D, parathyroid hormone, secondary hyperparathyroidism, UV irradiation, 7-dehydrocholesterol, previtamin D3, vitamin D2, body fat storage
MeSH terms: Adult, Biological Availability, Cholecalciferol, Ergocalciferols, Humans, Intestinal Absorption, Obesity, Reference Values, Skin, Ultraviolet Rays, Vitamin D, Body Mass Index

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Decreased bioavailability of vitamin D in obesity

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks