Human skin condition and its associations with nutrient concentrations in serum and diet
Open accessAbstract
Background Nutritional factors exert promising actions on the skin, but only scant information is available on the modulating effects of physiologic concentrations of nutrients on the skin condition of humans.Objective The objective was to evaluate whether nutrient concentrations in serum and diet are associated with the skin condition of humans.Design A cross-sectional study was conducted in which data on serum concentrations of nutrients, dietary intake of nutrients, and the hydration, sebum content, and surface pH of skin were obtained from 302 healthy men and women. Skin condition was measured with the use of noninvasive techniques. Dietary intake was assessed with 2 complementary food-frequency questionnaires. Multiple regression analysis was used to evaluate associations of serum vitamins and carotenoids and of dietary micro- and macronutrients with skin condition.Results After adjustment for potential confounders, including sex, age, and smoking, statistically significant associations were shown in the total population between serum vitamin A and skin sebum content and surface pH and between the dietary intake of total fat, saturated fat, monounsaturated fat, and skin hydration. Monounsaturated fat intake was also associated with surface pH. Associations between serum beta-cryptoxanthin and skin hydration and between surface pH and fluid and calcium intakes were observed in men only.Conclusion Several associations between nutrients in serum and diet and skin condition were observed, indicating that changes in baseline nutritional status may affect skin condition.
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A balanced diet plays an important role in the proper functioning of the human body, including the skin.
“A balanced diet plays an important role in the proper functioning of the human body, including the skin.”
From Bioactive Compounds for Skin Health: A Review (2021) · cites this paper as [15]
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- Authors
- Boelsma, E., van de Vijver, L. P., Goldbohm, R. A., Klöpping-Ketelaars, I. A., Hendriks, H. F., & Roza, L.
- Affiliations
- Netherlands Organisation for Applied Scientific Research (NL)
- ORCID
- Hendriks, Henk FJ
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 2003-02
- Volume
- 77
- Issue
- 2
- Pages
- 348-355
- ISSN
- 0002-9165 (ISSN-L)
- OpenAlex
- W2131244892
- Cited by
- 123
- References
- 41
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 14 · 2023: 5 · 2022: 5 · 2021: 10 · 2020: 4 · 2019: 5 · 2018: 8 · 2017: 6 · 2016: 4 · 2015: 11 · 2014: 4 · 2013: 3 · 2012: 3
- FWCI
- 2.00
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- American Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- TNO Repository (submittedVersion)
- Repository hosted by TU Delft Library (TU Delft) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
- Keywords
- skin diseases, dietary intake, vitamin A, beta-cryptoxanthin, carotenoids, skin hydration, sebum content, skin pH, monounsaturated fatty acids, saturated fat, total fat intake, calcium intake, fluid intake, nutritional status
- MeSH terms
- Adolescent, Adult, Aged, Cross-Sectional Studies, Diet, Feeding Behavior, Female, Health Status, Humans, Hydrogen-Ion Concentration, Male, Middle Aged, Nutritional Physiological Phenomena, Surveys and Questionnaires, Regression Analysis, Sebum, Skin, Skin Diseases, Skin Physiological Phenomena, Smoking, Vitamins, Micronutrients
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