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Cited by 102Diet, Metabolism, and DiseaseObesity, Physical Activity, DietRegulation of Appetite and Obesity

The DOI matches its Crossref record; 63 of the 65 references it cites were found in a registry or an index.

Sugars, energy metabolism, and body weight control

Open access
Saris, Wim HM·2003·The American Journal of Clinical Nutrition
DOI 10.1093/ajcn/78.4.850s
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Abstract

Obesity represents a major threat to health and quality of life. Although obesity has strong genetic determinants, it is generally accepted that it results from an imbalance between food intake and daily physical activity. Health guidelines have been focused on 3 particular lifestyle factors: increased levels of physical activity and reductions in the intakes of fat and sugars. The dietary guidelines, especially, are under debate. This review covers evidence from carefully controlled laboratory studies, clinical trials, studies in populations at high risk of developing obesity, and epidemiologic studies on the role of sugars, particularly sucrose, in the development of obesity. Although many environmental factors promote a positive energy balance, it is clear that the consumption of a low-carbohydrate, high-fat diet increases the likelihood of weight gain. The evidence related to carbohydrate, particularly sugars, and the type of food (solid or liquid) is less clear because the number of long-term ad libitum dietary intervention trials is very small. Data on sucrose intake in relation to metabolism and weight gain do not associate high consumption of sucrose with the prevalence of obesity. The evidence supports the current dietary guidelines for reducing fat intake. However, the effect of the carbohydrate source and class and of the form in which carbohydrate is consumed (solid or liquid) on body weight control requires further consideration.

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Research works printed but not linked: 2

  1. Katan, 1997, Beyond low fat diets, N Engl J Med, 337, 563
  2. Saris, 1997, Effects of exercise intensity on 24-h substrate metabolism in obese men, Int J Obes Relat Metab Disord, 21, S75

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Metadata

Authors
Saris, W. H.
Affiliations
Maastricht University (NL)
Corresponding author
Saris, Wim HM
ORCID
Saris, Wim HM
Venue
The American Journal of Clinical Nutrition
Publisher
Elsevier BV
Published
2003-10
Volume
78
Issue
4
Pages
850S-857S
ISSN
0002-9165 (ISSN-L)
DOI
10.1093/ajcn/78.4.850s
OpenAlex
W2125063102
Cited by
102
References
65
Citations by year
2026: 1 · 2025: 4 · 2023: 1 · 2022: 1 · 2021: 2 · 2020: 3 · 2019: 1 · 2018: 2 · 2017: 2 · 2016: 5 · 2015: 6 · 2014: 6 · 2013: 7 · 2012: 9
FWCI
1.01
Type
journal article
Language
en
Open access
Licence
Locations
  • American Journal of Clinical Nutrition (publishedVersion)
  • PubMed (publishedVersion)
  • Research Publications (Maastricht University) (publishedVersion, other-oa)
  • Research Publications (Maastricht University) (submittedVersion, other-oa)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
Keywords
sugar consumption, sucrose, obesity, weight management, energy balance, dietary guidelines, low-carbohydrate high-fat diet, carbohydrate sources, energy metabolism, dietary fat intake
MeSH terms
Adult, Analysis of Variance, Body Weight, Dietary Carbohydrates, Energy Metabolism, Female, Humans, Obesity, Randomized Controlled Trials as Topic, Glycemic Index

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