CoChat
Sign Up
Cited by 66Nutritional Studies and DietDiet and metabolism studiesDietary Effects on Health

Effects of a vegetarian diet and treatment preference on biochemical and dietary variables in overweight and obese adults: a randomized clinical trial

Open access
Burke, Lora E, Hudson, Alana G, Warziski, Melanie T, Styn, Mindi A, Music, Edvin, Elci, Okan U, Sereika, Susan M·2007·The American Journal of Clinical Nutrition
DOI 10.1093/ajcn/86.3.588
Open this paper in CoChat — free accountOpen PDF

Abstract

Background A vegetarian diet may lead to numerous health benefits, including weight loss. Objective We examined the joint effects of personal preference of dietary treatment and a calorie-restricted, low-fat lactoovovegetarian diet (LOV-D) compared with a standard calorie-restricted, low-fat omnivorous diet (STD-D) on changes in weight, total cholesterol, ratio of LDL to HDL cholesterol (LDL:HDL cholesterol), triacylglycerols, insulin resistance, and macronutrient intake during an 18-mo study. Design This was a randomized clinical trial of 176 overweight and obese adults who were recruited and randomly assigned first to 1 of 2 preference conditions (yes or no). If assigned to Preference-No, they were randomly assigned to 1 of the 2 diet conditions (STD-D or LOV-D). If assigned to Preference-Yes, they were assigned to the diet they indicated as preferred at screening. The 12-mo intervention was followed by a 6-mo maintenance phase. Results Participants were mainly women (86.9%) and white (70.5%); 75% completed the 18-mo study. A significant interaction between preference and dietary treatment was not observed for any of the outcome variables. However, participants in the Preference-No groups significantly decreased their triacylglycerols (P = 0.04). The only effect observed for diet was a borderline significant decrease in LDL:HDL cholesterol for the LOV-D group (P = 0.06). Within the LOV-D groups, those who were 100% adherent to the LOV-D had significant and marginally significant reductions in monounsaturated fat (P = 0.02) and total fat (P = 0.05) intakes at 18 mo. Conclusions Our findings suggest that neither prescribing a vegetarian diet nor allowing persons to choose their preferred diet had a significant effect on outcome measures. However, all participants had a significant reduction in total energy and fat intakes and an increase in energy expenditure, which was reflected in reduced body weight. This clinical trial was registered at www.clinicaltrials.gov as NCT00330629.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1093/ajcn/86.3.588

Cites

34 of 34 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Three other trials found no differences between lacto-vegetarian or vegan diets versus conventional dietary recommendations for improving weight loss, blood pressure, blood lipids, or insulin resistance.

    “Three other trials found no differences between lacto-vegetarian or vegan diets versus conventional dietary recommendations for improving weight loss, BP, blood lipids, or insulin resistance.119–122”

    From Components of a Cardioprotective Diet: New Insights (2011) · cites this paper as [122]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Burke, L. E., Hudson, A. G., Warziski, M. T., Styn, M. A., Music, E., Elci, O. U., & Sereika, S. M.
Affiliations
University of Pittsburgh (US)
Corresponding author
Burke, Lora E
ORCID
Venue
The American Journal of Clinical Nutrition
Publisher
Elsevier BV
Published
2007-09
Volume
86
Issue
3
Pages
588-596
ISSN
0002-9165 (ISSN-L)
DOI
10.1093/ajcn/86.3.588
OpenAlex
W1896734186
Cited by
66
References
34
Citations by year
2024: 2 · 2023: 1 · 2022: 5 · 2021: 4 · 2020: 1 · 2019: 2 · 2018: 5 · 2017: 5 · 2015: 6 · 2014: 4 · 2013: 6 · 2012: 3
FWCI
4.82
Type
journal article
Language
en
Open access
Licence
Locations
  • American Journal of Clinical Nutrition (publishedVersion)
  • PubMed (publishedVersion)
  • D-Scholarship@Pitt (University of Pittsburgh) (acceptedVersion)
Funders
  • University of Pittsburgh
  • Deutsches Krebsforschungszentrum
  • National Institutes of Health (UL1TR000005, 046204, 5p30dk046204-15, RR00056)
  • National Institute of Nursing Research (P30NR003924, P30-NR-03924)
  • National Institute of Diabetes and Digestive and Kidney Diseases ((DK 046204, R01-DK58631, R01DK058631)
  • National Center for Research Resources (M01RR000056, 5 M01 RR00056, RR 00056, 5 MO1 RR 00056)
  • National Center for Advancing Translational Sciences
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Medicine › Physiology › Diet and metabolism studies
  • Health Sciences › Medicine › Physiology › Dietary Effects on Health
Keywords
vegetarian diet, lacto-ovo-vegetarian diet, overweight, obesity, weight loss, caloric restriction, low-fat diet, LDL/HDL ratio, triglycerides, insulin resistance, macronutrient intake, monounsaturated fatty acids, energy expenditure, dietary adherence
MeSH terms
Adult, Blood Chemical Analysis, Cholesterol, Diet, Reducing, Female, Follow-Up Studies, Food Preferences, Humans, Insulin Resistance, Cholesterol, HDL, Cholesterol, LDL, Male, Middle Aged, Obesity, Patient Compliance, Time Factors, Triglycerides, Diet, Vegetarian, Exercise, Body Mass Index, Treatment Outcome, Diet, Fat-Restricted, Overweight

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review