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Cited by 25Reproductive tract infections researchMathematical and Theoretical Epidemiology and Ecology ModelsHIV/AIDS Research and Interventions

Investigating the potential public health benefit of jail-based screening and treatment programs for chlamydia.

Owusu-Edusei, K., Gift, T. L., Chesson, H. W., Kent, C. K.·2013·American Journal of Epidemiology
DOI 10.1093/aje/kws240
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Abstract

Observational studies have found mixed results on the impact of jail-based chlamydia screen-and-treat programs on community prevalence. In the absence of controlled trials or prospectively designed studies, dynamic mathematical models that incorporate movements in and out of jail and sexual contacts (including disease transmission) can provide useful information. We explored the impact of jail-based chlamydia screening on a hypothetical community's prevalence with a deterministic compartmental model focusing on heterosexual transmission. Parameter values were obtained from the published literature. Two analyses were conducted. One used national values (large community); the other used values reported among African Americans--the population with the highest incarceration rates and chlamydia burden (small community). A comprehensive sensitivity analysis was carried out. For the large-community analysis, chlamydia prevalence decreased by 13% (from 2.3% to 2.0%), and based on the ranges of parameter values (including screening coverage of 10%-100% and a postscreening treatment rate of 50%-100%) used in the sensitivity analysis, this decrease ranged from 0.1% to 58%. For the small-community analysis, chlamydia prevalence decreased by 54% (from 4.6% to 2.1%). Jail-based chlamydia screen-and-treat programs have the potential to reduce chlamydia prevalence in communities with high incarceration rates. However, the magnitude of this potential decrease is subject to considerable uncertainty.

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Crossref · 10.1093/aje/kws240

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  • The impact of screening in correctional facilities on the prevalence of infections among detainees and subsequent transmission in the community after release might be considerable.

    “However, because of the mobility of incarcerated populations in and out of the community, the impact of screening in correctional facilities on the prevalence of infections among detainees and subsequent transmission in the community after release might be considerable (378).”

    From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [378]

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Authors
Owusu-Edusei, K., Gift, T. L., Chesson, H. W., & Kent, C. K.
Affiliations
Centers for Disease Control and Prevention (US)
ORCID
Venue
American Journal of Epidemiology
Publisher
Oxford University Press (OUP)
Published
2013-02-12
Volume
177
Issue
5
Pages
463-473
ISSN
  • 0002-9262 (ISSN-L)
  • 1476-6256
DOI
10.1093/aje/kws240
OpenAlex
W2134153487
Cited by
25
References
57
Citations by year
2025: 1 · 2024: 1 · 2022: 3 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 3 · 2017: 1 · 2016: 2 · 2015: 3 · 2014: 4 · 2013: 1
FWCI
3.06
Type
journal article
Language
en
Open access
closed
Locations
  • American Journal of Epidemiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Mathematical and Theoretical Epidemiology and Ecology Models
  • Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
Keywords
chlamydia, incarceration, sexually transmitted infections, chlamydia prevalence, compartmental model, heterosexual transmission, African Americans, public health impact, screening coverage, treatment rates
MeSH terms
Adolescent, Adult, Chlamydia Infections, Female, Humans, Male, Mass Screening, Models, Theoretical, Prisons, Public Health, Prevalence, Cost of Illness, Disease Transmission, Infectious

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