CoChat
Sign Up
Cited by 73Childhood Cancer Survivors' Quality of LifeCancer survivorship and careMultiple and Secondary Primary Cancers

Late effects in adult survivors of childhood cancer: the need for life-long follow-up

Open access
Blaauwbroek, R., Groenier, K.H., Kamps, W.A., Meyboom-de Jong, B., Postma, A.·2007·Annals of Oncology
DOI 10.1093/annonc/mdm336
Open this paper in CoChat — free accountOpen PDF

Abstract

Background To assess health status and health-related quality of life (HRQoL) in childhood cancer survivors who were not involved in regular long-term follow-up. Patients and methods One hundred and twenty-three long-term survivors, median age 33 (19-50) years, follow-up 27 (9-38) years, were recalled to the long-term follow-up clinic. Most of them were treated in the period 1970-1990. Late effects were graded using the Common Terminology Criteria for Adverse Events, version 3 (CTCAEv3). HRQoL was assessed by RAND-36. Socio-economic factors were compared with data from Statistics Netherlands (CBS). Results Grade 1-2 late effects were found in 54% of the survivors, grade 3-4 in 39%, two or more late effects in 70% and grade 2-4 previously unknown late effects in 33%. Survivors had significantly lower scores on RAND-36 compared with controls. Conclusions As nearly 40% of these long-term childhood cancer survivors suffer from moderate to severe late effects and 33% had previously unknown late effects it is worthwhile recalling these patients to follow-up. Where and by whom this follow-up can best be done is still a question that needs to be answered.

Integrity signals

Registry

Crossref · 10.1093/annonc/mdm336

Cites

26 of 26 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Available studies often evaluate outcomes in adult survivors of childhood leukemia.

    “Firstly, available studies often evaluate outcomes in adult survivors of childhood leukemia (Blaauwbroek et al., 2007; Edelmann et al., 2014; Kanellopoulos et al., 2015; Tamnes et al., 2015; Zeller et al., 2013).”

    From Brain structure, working memory and response inhibition in childhood leukemia survivors (2017) · cites this paper as Blaauwbroek et al., 2007

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Blaauwbroek, R., Groenier, K. H., Kamps, W. A., Meyboom-de Jong, B., & Postma, A.
Affiliations
University Medical Center Groningen (NL)
Corresponding author
Blaauwbroek, R.
ORCID
Groenier, K.H.
Venue
Annals of Oncology
Publisher
Elsevier BV
Published
2007-11
Volume
18
Issue
11
Pages
1898-1902
ISSN
0923-7534 (ISSN-L)
DOI
10.1093/annonc/mdm336
OpenAlex
W2109655834
Cited by
73
References
26
Citations by year
2026: 2 · 2025: 3 · 2024: 4 · 2023: 3 · 2022: 5 · 2021: 5 · 2020: 5 · 2019: 3 · 2018: 2 · 2017: 2 · 2016: 6 · 2015: 2 · 2014: 2 · 2013: 5 · 2012: 4
FWCI
5.39
Type
journal article
Language
en
Open access
Licence
Locations
  • Annals of Oncology (publishedVersion)
  • PubMed (publishedVersion)
  • University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion, other-oa)
  • HighWire Press Open Archive (submittedVersion)
  • University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion, other-oa)
Topics
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Health Sciences › Medicine › Epidemiology › Multiple and Secondary Primary Cancers
Keywords
childhood cancer survivors, late effects, health-related quality of life, long-term follow-up, RAND-36, CTCAE grading, socioeconomic factors
MeSH terms
Adolescent, Adult, Child, Child, Preschool, Female, Follow-Up Studies, Health Status Indicators, Hospitals, University, Humans, Male, Middle Aged, Neoplasms, Netherlands, Predictive Value of Tests, Probability, Quality of Life, Time Factors, Survivors, Needs Assessment

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review