Effects of ambient air pollution on outpatient visits for psoriasis in Wuhan, China: a time-series analysis
Abstract
Background Psoriasis can be provoked by both external and internal factors. The effects of environmental factors on psoriasis remain unclear. Objectives To investigate the effects of air pollution on outpatient visits for psoriasis. Methods A distributed lag nonlinear model following quasi-Poisson regression was used to evaluate the lag effects of air pollutants on psoriasis outpatient visits, adjusting for potential confounders. Stratified analyses were performed to identify potential effect modifications by sex, age and season. Results In total, 13 536 outpatient visits for psoriasis were recorded in Wuhan, China from 1 January 2015 to 31 December 2019. In the single-pollutant model, exposures to particulate matter (PM) smaller than 2.5 μm (PM2.5), PM smaller than 10 μm (PM10), NO2 and SO2 were found to be significantly associated with increased daily psoriasis outpatient visits. For the largest effects, a 10-μg m-3 increase in concentrations of PM2.5 (lag1), PM10 (lag1), NO2 (lag0) and SO2 (lag3) corresponded to 0.32% [95% confidence interval (CI) 0.01-0.63], 0.26% (95% CI 0.05-0.48), 0.98% (95% CI 0.01-1.96) and 2.73% (95% CI 1.01-4.47) increases in psoriasis outpatient visits, respectively. In the two-pollutant model, only NO2 showed significant and stable effects on the outpatient visits for psoriasis. Conclusions Ambient air pollution, especially NO2, appears to be significantly associated with an increased risk of outpatient visits for psoriasis in Wuhan, China. Air p…
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A study found a higher risk for patients with psoriasis in the age group between 18 and 45 years and in women in association with PM2.5, PM10, and NO2.
“a study found a higher risk for patients with psoriasis in the age group between 18 and 45 years and in women in association with PM2.5, PM10, and NO2 [69].”
From Air Pollution and Skin Diseases: A Systematic Review of Epidemiological Evidence (2026) · cites this paper as [69]
The lag effect of air pollution on psoriasis was evident and varied between 0 and 7 days, with the highest effect observed between lag 0-3.
“The lag effect of AP on psoriasis was evident and varied between 0 and 7 days, with the highest effect observed between lag 0–3 [69, 71].”
From Air Pollution and Skin Diseases: A Systematic Review of Epidemiological Evidence (2026) · cites this paper as [69]
A season-specific analysis showed a higher risk of psoriasis during the cold season.
“A season-specific analysis showed a higher risk during the cold season [22, 69, 71].”
From Air Pollution and Skin Diseases: A Systematic Review of Epidemiological Evidence (2026) · cites this paper as [69]
In studies analyzing multiple air pollutants, the short-term association between psoriasis and air pollution showed a strong relationship with gaseous pollutants such as NO2, SO2, and CO.
“it was observed that a short-term association between psoriasis and AP showed a strong relationship with gaseous pollutants such as NO2, SO2, and CO [66, 68, 69]”
From Air Pollution and Skin Diseases: A Systematic Review of Epidemiological Evidence (2026) · cites this paper as [69]
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- Authors
- Lan, J., Huang, Q., Yang, L., Li, Y., Yang, J., Jiang, B., Zhao, L., Xia, Y., Yu, X., & Tao, J.
- Affiliations
- Huazhong University of Science and Technology (CN)
- Wuhan Union Hospital (CN)
- Corresponding author
- Tao, Juan
- Venue
- British Journal of Dermatology
- Publisher
- Oxford University Press (OUP)
- Published
- 2022-12-19
- Volume
- 188
- Issue
- 4
- Pages
- 491-498
- ISSN
- 0007-0963 (ISSN-L)
- 1365-2133
- OpenAlex
- W4316276778
- Cited by
- 36
- References
- 11
- Citations by year
- 2026: 9 · 2025: 15 · 2024: 9 · 2023: 3
- FWCI
- 2.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- British Journal of Dermatology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (82130089, 82103730, 82071844)
- Hubei Engineering Research Center of Skin Disease Theranostics and Health (2020-420103-84-03-072248)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Air Quality and Health Impacts
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Climate Change and Health Impacts
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Indoor Air Quality and Microbial Exposure
- Keywords
- psoriasis, ambient air pollution, outpatient visits, particulate matter, PM2.5, PM10, nitrogen dioxide, sulfur dioxide, lagged effects, effect modification, Wuhan
- MeSH terms
- Air Pollutants, Air Pollution, China, Environmental Pollutants, Humans, Nitrogen Dioxide, Outpatients, Particulate Matter
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