THE NEUROLOGY OF OBSESSIONAL SLOWNESS
Abstract
Seventeen of 59 patients admitted to hospital for treatment of Obsessive-Compulsive Disorder (OCD) were found to have significant slowness, mainly due to difficulty in initiating goal-directed action and suppressing intrusive and perseverative behaviour. In this subgroup subtle neurological abnormalities were found more frequently than in healthy controls and included loss of motor fluency, hesitancy of initiation of limb movements, speech and gait abnormalities, cogwheel rigidity, complex repetitive movements and tics. Difficulties in cognitive set-shifting and complex spatial-and-shifting abilities were found on neuropsychological testing, but no correlation was found between these disturbances and either the degree of obsessionality or the severity of motor dysfunction. These results suggest that patients with obsessional slowness may have a dysfunction in the frontal-basal-ganglia loop system.
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Slowness can result from interference of obsessions with a task or impaired decision making.
“Slowness can also result from interference of obsessions with a task [44] or impaired decision making [45].”
From Projection-specific deficits in synaptic transmission in adult Sapap3-knockout mice (2020) · cites this paper as [44]
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Background[18F]FDG PET Study in Obsessive–Compulsive Disorder
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BackgroundDeclarative and Procedural Learning in Individuals With Subclinical Obsessive-Compulsive Symptoms
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“However, as in previous studies, the groups differed significantly on measures obsessional slowness (Hymas et al., 1991) and depression (BDI).”
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- Authors
- HYMAS, N., LEES, A., BOLTON, D., EPPS, K., & HEAD, D.
- Affiliations
- Fulbourn Hospital (GB)
- National Hospital for Neurology and Neurosurgery (GB)
- Corresponding author
- HYMAS, N.
- ORCID
- Venue
- Brain
- Publisher
- Oxford University Press (OUP)
- Published
- 1991
- Volume
- 114
- Issue
- 5
- Pages
- 2203-2233
- ISSN
- 0006-8950 (ISSN-L)
- 1460-2156
- OpenAlex
- W2041441236
- Cited by
- 152
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 4 · 2023: 2 · 2022: 4 · 2021: 8 · 2020: 3 · 2018: 1 · 2017: 5 · 2016: 3 · 2015: 6 · 2014: 6 · 2013: 2 · 2012: 9
- FWCI
- 5.38
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Brain (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Health Sciences › Medicine › Neurology › Neurological disorders and treatments
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- obsessive-compulsive disorder, motor fluency, perseveration, intrusive thoughts, cogwheel rigidity, tics, set-shifting, frontal lobe dysfunction, neuropsychological deficits
- MeSH terms
- Adolescent, Adult, Aged, Brain, Female, Humans, Male, Middle Aged, Motor Skills, Movement, Nervous System, Neuropsychological Tests, Obsessive-Compulsive Disorder, Radionuclide Imaging, Time Factors
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