Neuromagnetic evidence for a pitch processing center in Heschl's gyrus
Abstract
There have been several attempts to use the neuromagnetic response to the onset of a tonal sound (N100m) to study pitch processing in auditory cortex. Unfortunately, a large proportion of the N100m is simply a response to the onset of sound energy, independent of whether the sound produces a pitch. The current study describes a novel stimulus paradigm designed to circumvent the energy-onset response and thereby isolate the response of those neural elements specifically involved in pitch processing. The temporal resolution of magnetoencephalography enables us to show that the latency and amplitude of this pitch-onset response (POR) vary with the pitch and pitch strength of the tone. The spatial resolution is sufficient to show that its source lies somewhat anterior and inferior to that of the N100m, probably in the medial part of Heschl's gyrus.
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MEG indicates that the N1 ERP component originates in the superior temporal gyrus.
“Magnetoencephalography (MEG), the magnetic counterpart of EEG, indicates that the N1 ERP component originates in the STG (Krumbholz et al., 2003).”
From Auditory verbal hallucinations as atypical inner speech monitoring, and the potential of neurostimulation as a treatment option (2013) · cites this paper as Krumbholz et al., 2003
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- Authors
- Krumbholz, K.
- Affiliations
- University Hospital Münster (DE)
- Corresponding author
- Krumbholz, K.
- ORCID
- Krumbholz, K.
- Venue
- Cerebral Cortex
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-07-01
- Volume
- 13
- Issue
- 7
- Pages
- 765-772
- ISSN
- 1047-3211 (ISSN-L)
- 1460-2199
- OpenAlex
- W2130721922
- Cited by
- 260
- References
- 26
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 8 · 2023: 17 · 2022: 9 · 2021: 7 · 2020: 6 · 2019: 8 · 2018: 5 · 2017: 14 · 2016: 10 · 2015: 13 · 2014: 15 · 2013: 13 · 2012: 14
- FWCI
- 6.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cerebral Cortex (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
- Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
- Keywords
- pitch processing, Heschl's gyrus, N100m, auditory cortex, pitch strength, auditory evoked potentials, magnetoencephalography, source localization
- MeSH terms
- Acoustic Stimulation, Auditory Cortex, Brain Mapping, Evoked Potentials, Auditory, Humans, Noise, Pitch Discrimination, Pitch Perception, Reaction Time, Magnetoencephalography
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