Processing of complex stimuli and natural scenes in the auditory cortex
Abstract
Neuronal responses in auditory cortex show a fascinating mixture of characteristics that span the range from almost perfect copies of physical aspects of the stimuli to extremely complex context-dependent responses. Fast, highly stimulus-specific adaptation and slower plastic mechanisms work together to constantly adjust neuronal response properties to the statistics of the auditory scene. Evidence with converging implications suggests that the neuronal activity in primary auditory cortex represents sounds in terms of auditory objects rather than in terms of invariant acoustic features.
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The brain exhibits extreme anatomical specialization with distinct cell types, circuit motifs, and processing principles across regions.
“The brain exhibits extreme anatomical specialization with distinct cell types, circuit motifs, and processing principles across regions—from the unique neuronal types of the cerebellum to the columnar organization of sensory cortices to the distinct microcircuits of the basal ganglia (Harris and Shepherd 2015; Nelken 2004).”
From The myth of the Bayesian brain (2025) · cites this paper as Nelken 2004
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“…anatomical specialization with distinct cell types, circuit motifs, and processing principles across regions—from the unique neuronal types of the cerebellum to the columnar organization of sensory cortices to the distinct micro-circuits of the basal ganglia (Harris and Shepherd 2015; Nelken 2004).”
- Authors
- Nelken, I.
- Affiliations
- Hebrew University of Jerusalem (IL)
- Corresponding author
- Nelken, Israel
- ORCID
- Nelken, Israel
- Venue
- Current Opinion in Neurobiology
- Publisher
- Elsevier BV
- Published
- 2004-08
- Volume
- 14
- Issue
- 4
- Pages
- 474-480
- ISSN
- 0959-4388 (ISSN-L)
- OpenAlex
- W2008652561
- Cited by
- 223
- References
- 63
- Citations by year
- 2026: 4 · 2025: 3 · 2024: 4 · 2023: 3 · 2022: 5 · 2021: 6 · 2020: 8 · 2019: 8 · 2018: 13 · 2017: 5 · 2016: 6 · 2015: 9 · 2014: 17 · 2013: 15 · 2012: 13
- FWCI
- 1.05
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Neurobiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Israel Science Foundation
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
- Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
- Physical Sciences › Computer Science › Signal Processing › Music and Audio Processing
- Keywords
- auditory cortex, natural sounds, context-dependent responses, stimulus-specific adaptation, neuroplasticity, complex stimuli, primary auditory cortex
- MeSH terms
- Action Potentials, Adaptation, Physiological, Animals, Auditory Cortex, Auditory Pathways, Auditory Perception, Humans, Models, Neurological, Neuronal Plasticity, Neurons, Afferent
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