Cited by 169Neuroscience and Neuropharmacology ResearchNeural dynamics and brain functionNeurotransmitter Receptor Influence on Behavior

The DOI matches its Crossref record; 57 of the 57 references it cites were found in a registry or an index.

Post-pubertal Emergence of Prefrontal Cortical Up States Induced by D1-NMDA Co-activation

Tseng, K. Y.·2004·Cerebral Cortex

DOI 10.1093/cercor/bhh107

Open this paper in CoChat — free account

Abstract

Dopamine-glutamate interactions may contribute to persistent electrical activity in the prefrontal cortex (PFC). We tested whether a D1 modulation of NMDA function can result in persistent depolarization in vitro. D1-NMDA co-activation yielded depolarizing plateaus resembling in vivo up states in PFC pyramidal neurons recorded in slices from adult (PD 45-65), but not pre-pubertal (PD 29-38) rats. These plateaus required intracellular Ca2+, activation of L-type Ca2+ channels and protein kinase A. These events were eliminated by intracellular administration of the voltage-gated Na+ channel blocker QX-314 or by interrupting synaptic activity with bath application of tetrodotoxin or the AMPA antagonist CNQX, suggesting that they require both intrinsic and synaptic mechanisms. These recurrent depolarizations could constitute important elements in cortical information processing, allowing synaptic plasticity and memory functions. Acquiring these PFC D1-NMDA interactions after puberty may be a critical element for developing mature cognitive abilities.

Integrity signals

Registry

Crossref · 10.1093/cercor/bhh107

Cites

57 of 57 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The adolescent brain and age-related behavioral manifestations
Spear, L. P. (2000) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(00)00014-2 · Cited by 5,433
Developmental and regional expression in the rat brain and functional properties of four NMDA receptors
Monyer, H., Burnashev, N., Laurie, D. J., Sakmann, B., & Seeburg, P. H. (1994) · Neuron · doi:10.1016/0896-6273(94)90210-0 · Cited by 3,535
Getting formal with dopamine and reward
Schultz, W. (2002) · Neuron · doi:10.1016/s0896-6273(02)00967-4 · Cited by 2,574
Neuronal Avalanches in Neocortical Circuits
Beggs, J. M., & Plenz, D. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-35-11167.2003 · Cited by 2,325
Cellular and network mechanisms of rhythmic recurrent activity in neocortex
Sanchez-Vives, M. V., & McCormick, D. A. (2000) · Nature Neuroscience · doi:10.1038/79848 · Cited by 1,539
Natural waking and sleep states: a view from inside neocortical neurons
Steriade, M., Timofeev, I., & Grenier, F. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.5.1969 · Cited by 1,296
Active propagation of somatic action potentials into neocortical pyramidal cell dendrites
Stuart, G. J., & Sakmann, B. (1994) · Nature · doi:10.1038/367069a0 · Cited by 1,289
Mesolimbocortical and nigrostriatal dopamine responses to salient non-reward events
Horvitz, J. C. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00019-1 · Cited by 967
The origins of two-state spontaneous membrane potential fluctuations of neostriatal spiny neurons
Wilson, C. J., & Kawaguchi, Y. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-07-02397.1996 · Cited by 798
Synaptic interactions among excitatory afferents to nucleus accumbens neurons: hippocampal gating of prefrontal cortical input
O’Donnell, P., & Grace, A. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-05-03622.1995 · Cited by 760

Show all 57 references

Sorted by citations

Items 101–169 of 169

NMDA and Dopamine: Diverse Mechanisms Applied to Interacting Receptor Systems
Cepeda, C., André, V. M., Jocoy, E. L., & Levine, M. S. (2009) · Europe PMC (PubMed Central) · Cited by 30
Post‐pubertal emergence of a dopamine phenotype in netrin‐1 receptor‐deficient mice
Grant, A., Speed, Z., Labelle‐Dumais, C., & Flores, C. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06919.x · Cited by 29
Induction and modulation of persistent activity in a layer V PFC microcircuit model
Papoutsi, A., Sidiropoulou, K., Cutsuridis, V., & Poirazi, P. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2013.00161 · Cited by 30
Early NMDA Receptor Ablation in Interneurons Causes an Activity-Dependent E/I Imbalance in vivo in Prefrontal Cortex Pyramidal Neurons of a Mouse Model Useful for the Study of Schizophrenia
Pafundo, D. E., Annan, C. A. P., Fulginiti, N. M., & Belforte, J. E. (2021) · Schizophrenia Bulletin · doi:10.1093/schbul/sbab030 · Cited by 27
Predictive Features of Persistent Activity Emergence in Regular Spiking and Intrinsic Bursting Model Neurons
Sidiropoulou, K., & Poirazi, P. (2012) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002489 · Cited by 27
A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.
Steullet, P., Lavoie, S., Kraftsik, R., Guidi, R., Gysin, R., Cuenod, M., & Do, K. (2008) · Free Radical Biology & Medicine · doi:10.1016/j.freeradbiomed.2007.12.006 · Cited by 29
Maturation of Corticolimbic Functional Connectivity During Sensitive Periods of Brain Development
Yang, S., & Tseng, K. Y. (2021) · Current topics in behavioral neurosciences · doi:10.1007/7854_2021_239 · Cited by 22
Self-citation
Inhibitory Contribution to Suprathreshold Corticostriatal Responses: An Experimental and Modeling Study
Flores-Barrera, E., Laville, A., Plata, V. T. G., Tapia, D., Bargas, J., & Galarraga, E. (2009) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-009-9394-2 · Cited by 23
Periadolescent changes of D2–AMPA interactions in the rat nucleus accumbens
Huppé‐Gourgues, F., & O’Donnell, P. (2011) · Synapse · doi:10.1002/syn.20976 · Cited by 23
Cortico-Subcortical Dynamics in Parkinson¿s Disease
Cuomo, D., Platania, P., SCIAMANNA, G., Tassone, A., MARTELLA, G., MADEO, G., & PISANI, A. (2009) · Humana Press eBooks · doi:10.1007/978-1-60327-252-0 · Cited by 21
Dendritic Nonlinearities Reduce Network Size Requirements and Mediate ON and OFF States of Persistent Activity in a PFC Microcircuit Model
Papoutsi, A., Sidiropoulou, K., & Poirazi, P. (2014) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1003764 · Cited by 20
Cannabinoid CB1 receptor-sensitive neurodevelopmental processes and trajectories
Tseng, K. Y., & Molla, H. M. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03057-2 · Cited by 20
Self-citation
Adolescent GBR12909 exposure induces oxidative stress, disrupts parvalbumin-positive interneurons, and leads to hyperactivity and impulsivity in adult mice
Khan, A., de Jong, L. A. W., Kamenski, M. E., Higa, K. K., Lucero, J. D., Young, J. W., Behrens, M. M., & Powell, S. B. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.11.022 · Cited by 19
Comparison of the adolescent and adult mouse prefrontal cortex proteome
Agoglia, A. E., Holstein, S. E., Small, A., Spanos, M., Burrus, B., & Hodge, C. W. (2017) · PLoS ONE · doi:10.1371/journal.pone.0178391 · Cited by 22
Divergent prefrontal dopaminergic mechanisms mediate drug- and fear-associated cue extinction during adolescence versus adulthood
Zbukvic, I., & Kim, J. H. (2017) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2017.11.004 · Cited by 19
Adolescence: a time of transition for the phenotype of dcc heterozygous mice
Yetnikoff, L., Pokinko, M., Arvanitogiannis, A., & Flores, C. (2014) · Psychopharmacology · doi:10.1007/s00213-013-3083-z · Cited by 18
High frequency stimulation-induced plasticity in the prelimbic cortex of rats emerges during adolescent development and is associated with an increase in dopamine receptor function
Kang, S., Cox, C. L., & Gulley, J. M. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.08.037 · Cited by 18
Genetic Feedback Regulation of Frontal Cortical Neuronal Ensembles Through Activity-Dependent Arc Expression and Dopaminergic Input
Mastwal, S. S., Cao, V. Y., & Wang, K. H. (2016) · Frontiers in Neural Circuits · doi:10.3389/fncir.2016.00100 · Cited by 16
Age-Dependent D1–D2 Receptor Coactivation in the Lateral Orbitofrontal Cortex Potentiates NMDA Receptors and Facilitates Cognitive Flexibility
Thompson, J. L., Yang, J., Lau, B. K., Liu, S., Baimel, C., Kerr, L. E., Liu, F., & Borgland, S. L. (2015) · Cerebral Cortex · doi:10.1093/cercor/bhv222 · Cited by 17
Staging Perspectives in Neurodevelopmental Aspects of Neuropsychiatry: Agents, Phases and Ages at Expression
Archer, T., Kostrzewa, R. M., Beninger, R. J., & Palomo, T. (2010) · Neurotoxicity Research · doi:10.1007/s12640-010-9162-6 · Cited by 16
Contribution of Dopamine D1/5 Receptor Modulation of Post-Spike/Burst Afterhyperpolarization to Enhance Neuronal Excitability of Layer V Pyramidal Neurons in Prepubertal Rat Prefrontal Cortex
Yi, F., Zhang, X., Yang, C. R., & Li, B. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071880 · Cited by 18
Local N-Methyl-D-Aspartate Receptor Antagonism in the Prefrontal Cortex Attenuates Spatial Cognitive Deficits Induced by Gonadectomy in Adult Male Rats
Locklear, M., Bhamidipaty, S., & Kritzer, M. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.12.032 · Cited by 16
Juvenile exposure to ketamine causes delayed emergence of EEG abnormalities during adulthood in mice
Featherstone, R. E., Nagy, L. R., Hahn, C.-G., & Siegel, S. J. (2013) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2013.09.017 · Cited by 15
Social isolation postweaning alters reward-related dopamine dynamics in a region-specific manner in adolescent male rats
Lallai, V., Congiu, C., Craig, G., Manca, L., Chen, Y.-C., Dukes, A. J., Fowler, C. D., & Dazzi, L. (2024) · Neurobiology of Stress · doi:10.1016/j.ynstr.2024.100620 · Cited by 14
The anatomy of co-morbid neuropsychiatric disorders based on cortico-limbic synaptic interactions
Totterdell, S. (2006) · Neurotoxicity Research · doi:10.1007/bf03033236 · Cited by 13
Brief dopaminergic stimulations produce transient physiological changes in prefrontal pyramidal neurons
Moore, A. R., Zhou, W., Potapenko, E. S., Kim, E., & Antic, S. D. (2010) · Brain Research · doi:10.1016/j.brainres.2010.10.111 · Cited by 12
Chronic administration of risperidone in a rat model of schizophrenia: A behavioural, morphological and molecular study
Castellano, O., Arji, M., Sancho, C., Carro, J., Riolobos, A. S., Molina, V., Gómez‐Nieto, R., Horta‐Júnior, J. D. A. C., Herrero-Turrión, M. J., & L�pez, D. E. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.12.036 · Cited by 12
Dopaminergic Modulation of Prefrontal Cortex Network Dynamics
Durstewitz, D. (2007) · Springer eBooks · doi:10.1007/978-0-387-72256-6_15 · Cited by 11
Effect of dopamine receptor stimulation on voltage-dependent fast-inactivating Na+ currents in medial prefrontal cortex (mPFC) pyramidal neurons in adult rats
Szulczyk, B., Książek, A., Ladno, W., & Szulczyk, P. J. (2012) · Acta Neurobiologiae Experimentalis · doi:10.55782/ane-2012-1907 · Cited by 10
Transient rhythmic network activity in the somatosensory cortex evoked by distributed input in vitro
Berger, T. K., Lüscher, H. R., & Giugliano, M. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.03.003 · Cited by 10
The brain structure underlying the nonlinear association between early-life tobacco smoke exposure and the risk for cognitive decline and dementia in adulthood: a large prospective cohort study
Lin, C., Lin, F., Yang, K., Zhong, Y., Luo, Y., Chen, H., Zhang, W., Chen, X., Ye, Q., Zeng, Y., et al. (2025) · BMC Public Health · doi:10.1186/s12889-025-21305-6 · Cited by 8
Age-dependent actions of dopamine on inhibitory synaptic transmission in superficial layers of mouse prefrontal cortex
Paul, K., & Cox, C. L. (2012) · Journal of Neurophysiology · doi:10.1152/jn.00756.2012 · Cited by 8
Diversity of Up-State Voltage Transitions During Different Network States
Vautrelle, N., Carrillo‐Reid, L., & Bargas, J. (2008) · Humana Press eBooks · doi:10.1007/978-1-60327-252-0_5 · Cited by 8
Prefrontal Cortex Dysfunction as a Precipitating Factor for Schizophrenia and Depression
Uliana, D. L., & Grace, A. A. (2026) · Journal of Neurochemistry · doi:10.1111/jnc.70409 · Cited by 8
Adolescent Maturation of Cortical Dopamine
O’Donnell, P. (2010) · Springer eBooks · doi:10.1007/978-1-4614-0785-0_11 · Cited by 7
Illness Phase as a Key Assessment and Intervention Window for Psychosis
Kohler, C. G., Wolf, D. H., Abi‐Dargham, A., Anticevic, A., Cho, Y., Fonteneau, C., Gil, R. B., Girgis, R. R., Gray, D. L., Grinband, J., et al. (2022) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2022.05.009 · Cited by 8
4.3 Postnatal Maturation of Dopamine Actions in the Prefrontal Cortex
O’Donnell, P., & Tseng, K. Y. (2009) · doi:10.1093/acprof:oso/9780195373035.003.0012 · Cited by 6
Self-citation
The impact of the mesoprefrontal dopaminergic system on the maturation of interneurons in the murine prefrontal cortex
Islam, K. U. S., & Blaess, S. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1403402 · Cited by 5
Dopamine and Norepinephrine Modulation of Cortical and Subcortical Dynamics During Visuomotor Learning
Rey, H. G., Lew, S. E., & Zanutto, B. S. (2007) · Springer eBooks · doi:10.1007/978-0-387-72256-6_17 · Cited by 5
Dopaminergic Modulation of Cortical and Striatal Up States
Tseng, K. Y., & O’Donnell, P. (2006) · Kluwer Academic Publishers eBooks · doi:10.1007/0-387-28066-9_44 · Cited by 4
Self-citation
Adolescent Exposure to Amphetamines and Vulnerability to Addiction
Hankosky, E. R., & Gulley, J. M. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800212-4.00028-5 · Cited by 4
Reorganization of dopamine circuitry in the anterior corpus callosum between early adolescence and adulthood in the mouse
Caldwell, M., Mendoza, J. C., Jiang, X. Y. Z., Alarcon, C., Ayo‐Jibunoh, V., Louis, S., Maronna, D., Darwish, R., Tomaio, J., Mingote, S., et al. (2024) · European Journal of Neuroscience · doi:10.1111/ejn.16385 · Cited by 3
Gating of Limbic Input to the Ventral Striatum
O’Donnell, P. (2010) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-12-374767-9.00021-4 · Cited by 3
Le développement du cerveau et les patterns de conduites typiques pendant l’adolescence (1re partie)
SPEAR, L. P. (2008) · PSN · doi:10.1007/s11836-008-0068-9 · Cited by 4
2.2 Functional Implications of Dopamine D2 Receptor Localization in Relation to Glutamate Neurons
Sesack, S. R. (2009) · doi:10.1093/acprof:oso/9780195373035.003.0003 · Cited by 3
NMDA and Dopamine
Jocoy, E. L., Cepeda, C., Levine, M. S., & André, V. M. (2008) · Frontiers in neuroscience · doi:10.1201/9781420044157.ch3 · Cited by 3
Prefrontal Cortical Dopamine Transmission
Sesack, S. R. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-418675-0.00015-8 · Cited by 5
Visualizing Striatal Networks. Focus on: “Encoding Network States by Striatal Cell Assemblies”
Rayport, S. (2008) · Journal of Neurophysiology · doi:10.1152/jn.00001.2008 · Cited by 2
Prefrontal Cortical Circuits and Schizophrenia Pathophysiology
O’Donnell, P. (2007) · Springer eBooks · doi:10.1007/978-0-387-72256-6_21 · Cited by 2
Adolescent neurocognitive development
Ravindranath, O., Parr, A. C., Perica, M. I., Elliott, S., & Luna, B. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-818872-9.00105-9 · Cited by 4
Alterations in dopaminergic innervation and receptors in focal cortical dysplasia
Meli, N., Sheran, K., Pitsch, J., Krabbe, S., Borger, V., Baumgartner, T. R., Becker, A. J., & Blaess, S. (2025) · Brain · doi:10.1093/brain/awaf080 · Cited by 1
Modelos fisiopatológicos de la esquizofrenia; de dopamina a glutamato, de glutamato a GABA
Rodrigo Paz, H. (2005) · Revista chilena de neuro-psiquiatría · doi:10.4067/s0717-92272005000400006 · Cited by 2
Efectos de la administración crónica de risperidona en un modelo de esquizofrenia en rata
Arji, M. (2010) · Gredos (University of Salamanca) · doi:10.14201/gredos.76398 · Cited by 1
Acquiring the Excitatory and the Inhibitory Action of Dopamine in the Prefrontal Cortex During Postnatal Development
Tseng, K.-Y. (2007) · Springer eBooks · doi:10.1007/978-0-387-72256-6_11
Self-citation
Dopamine and the Electrophysiology of Prefrontal Cortical Networks
O’Donnell, P. (2010) · doi:10.1002/9783527630271.ch7
Interplay Between Dopamine and Acetylcholine in the Modulation of Attention
Atzori, M., & Paz, R. D. (2007) · Springer eBooks · doi:10.1007/978-0-387-72256-6_19
Functions of the Medial Frontal Cortex A Model of Monoaminergic Modulation
Geday, J. (2009)
Development of the adolescent prefrontal cortex and basolateral amygdala and the effects of puberty and alcohol exposure
Koss, W. A. (2013) · Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)
Observing the Functional Maturation of the Female Prefrontal Cortex Using Ventral Hippocampal Stimulation
Veldran, L. E. (2017)
Le développement du cerveau et les patterns de conduites typiques pendant l’adolescence (2e partie)
SPEAR, L. P. (2008) · PSN · doi:10.1007/s11836-008-0070-2
Adolescent Maturation of Cortical Dopamine
O’Donnell, P. (2013) · Springer eBooks · doi:10.1007/978-1-4614-7264-3_13
Dopamine D1 and Glutamate N-Methyl-D-Aspartate Receptors: An Essential Interplay in Prefrontal Cortex Synaptic Plasticity
Kruse, M. S., & Jay, T. M. (2007) · Springer eBooks · doi:10.1007/978-0-387-72256-6_9
Integration of Cortical Activity by Striatal Medium Spiny Neurons
Kasanetz, F., & Murer, M. G. (2006) · Kluwer Academic Publishers eBooks · doi:10.1007/0-387-28066-9_45
Dopamine et contrôle de l’action : implication et maturation de la voie mésocorticale chez le rat
Naneix, F. (2011) · theses.fr (ABES) · doi:10.70675/001d4221ze950z4b8dz8178z8e2211b1bc4c
Alimentation durant l'adolescence : facteurs de troubles comportementaux et neurobiologiques à l'âge adulte : modèle animal chez le rat
Gueye, A. B. (2010) · theses.fr (ABES) · doi:10.70675/348ce609z5924z4ab5z9f76z80c1ef13a725
Impact d'une alimentation périnatale déséquilibrée sur le développement des circuits de la récompense chez le rat
Paradis, J. (2019) · theses.fr (ABES) · doi:10.70675/8f905b58z2fabz41bdz908dz6d84b37d8f67
Reelin in vulnerability and sex-dependent maturational trajectories of the prefrontal cortex
Silva-Hurtado, T. J. (2021) · theses.fr (ABES) · doi:10.70675/ecf0031ez1ac8z4688za735za4cd9acfc52c
High frequency stimulation-induced plasticity in the prelimbic cortex of rats emerges during adolescent development and is associated with an increase in dopamine receptor functionPreprint
Gulley, J. M., Kang, S., & Cox, C. L. (2018) · OSF Preprints (OSF Preprints)
Monoamine-Based Treatments in Schizophrenia: Time to Change the Paradigm?
Paz, R. D., & Tseng, K.-Y. (2007) · Springer eBooks · doi:10.1007/978-0-387-72256-6_20
Self-citation

Authors: Tseng, K. Y.
Affiliations: Albany Medical College (US)
Corresponding author: Tseng, K. Y.
Venue: Cerebral Cortex
Publisher: Oxford University Press (OUP)
Published: 2004-07-06
Volume: 15
Issue: 1
Pages: 49-57
ISSN: 1047-3211 (ISSN-L)
1460-2199
DOI: 10.1093/cercor/bhh107
OpenAlex: W2086932421
Cited by: 169
References: 57
Citations by year: 2026: 1 · 2025: 3 · 2024: 3 · 2022: 4 · 2021: 8 · 2020: 1 · 2019: 3 · 2018: 5 · 2017: 7 · 2016: 9 · 2015: 3 · 2014: 7 · 2013: 16 · 2012: 7
FWCI: 4.56
Type: journal article
Language: en
Open access: closed
Locations: Cerebral Cortex (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Mental Health (MH57683)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords: prefrontal cortex, up states, dopamine D1 receptor, NMDA receptor, dopamine-glutamate interaction, L-type calcium channels, protein kinase A, QX-314, tetrodotoxin, CNQX, synaptic plasticity, puberty, pyramidal neurons, cognitive development
MeSH terms: Action Potentials, Animals, Neural Pathways, Organ Culture Techniques, Sexual Maturation, Sodium Channels, Ion Channel Gating, 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine, Receptors, N-Methyl-D-Aspartate, N-Methylaspartate, Prefrontal Cortex, Receptors, Dopamine D1, Cyclic AMP-Dependent Protein Kinases, Pyramidal Cells, Patch-Clamp Techniques, Dopamine Agonists, Excitatory Amino Acid Agonists, Calcium Channels, L-Type, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Post-pubertal Emergence of Prefrontal Cortical Up States Induced by D1-NMDA Co-activation

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks