Event-Related Potential, Time-frequency, and Functional Connectivity Facets of Local and Global Auditory Novelty Processing: An Intracranial Study in Humans
Open accessAbstract
Auditory novelty detection has been associated with different cognitive processes. Bekinschtein et al. (2009) developed an experimental paradigm to dissociate these processes, using local and global novelty, which were associated, respectively, with automatic versus strategic perceptual processing. They have mostly been studied using event-related potentials (ERPs), but local spiking activity as indexed by gamma (60-120 Hz) power and interactions between brain regions as indexed by modulations in beta-band (13-25 Hz) power and functional connectivity have not been explored. We thus recorded 9 epileptic patients with intracranial electrodes to compare the precise dynamics of the responses to local and global novelty. Local novelty triggered an early response observed as an intracranial mismatch negativity (MMN) contemporary with a strong power increase in the gamma band and an increase in connectivity in the beta band. Importantly, all these responses were strictly confined to the temporal auditory cortex. In contrast, global novelty gave rise to a late ERP response distributed across brain areas, contemporary with a sustained power decrease in the beta band (13-25 Hz) and an increase in connectivity in the alpha band (8-13 Hz) within the frontal lobe. We discuss these multi-facet signatures in terms of conscious access to perceptual information.
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El Karoui et al. found that local deviants evoked high-gamma responses in temporal cortex.
“Using ECoG recordings, El Karoui et al. 181 found that local deviants (i.e., a tone differing from the preceding tone in a sequence; see Fig. 4A) evoked high‐gamma responses in temporal cortex, consistent with previous studies, but global deviants elicited sustained decreases in beta activity.”
From Evaluating the neurophysiological evidence for predictive processing as a model of perception (2020) · cites this paper as [181]
El Karoui et al. found that global deviants elicited sustained decreases in beta activity.
“Using ECoG recordings, El Karoui et al. 181 found that local deviants (i.e., a tone differing from the preceding tone in a sequence; see Fig. 4A) evoked high‐gamma responses in temporal cortex, consistent with previous studies, but global deviants elicited sustained decreases in beta activity.”
From Evaluating the neurophysiological evidence for predictive processing as a model of perception (2020) · cites this paper as [181]
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- Authors
- El Karoui, I., King, J.-R., Sitt, J., Meyniel, F., Van Gaal, S., Hasboun, D., Adam, C., Navarro, V., Baulac, M., Dehaene, S., Cohen, L., & Naccache, L.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Inserm (FR)
- ORCID
- Venue
- Cerebral Cortex
- Publisher
- Oxford University Press (OUP)
- Published
- 2014-06-26
- Volume
- 25
- Issue
- 11
- Pages
- 4203-4212
- ISSN
- 1047-3211 (ISSN-L)
- 1460-2199
- PMC
- PMC5635961
- OpenAlex
- W2014781736
- Cited by
- 114
- References
- 58
- Citations by year
- 2026: 7 · 2025: 9 · 2024: 19 · 2023: 12 · 2022: 9 · 2021: 11 · 2020: 11 · 2019: 11 · 2018: 7 · 2017: 8 · 2016: 3 · 2015: 7
- FWCI
- 3.35
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Cerebral Cortex (publishedVersion)
- PubMed (publishedVersion)
- UvA-DARE (University of Amsterdam) (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- HAL (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
- Keywords
- mismatch negativity, gamma power, beta power, alpha-band connectivity, functional connectivity, frontal lobe, intracranial recordings, epilepsy
- MeSH terms
- Acoustic Stimulation, Adolescent, Adult, Auditory Perception, Brain, Brain Mapping, Electroencephalography, Epilepsy, Evoked Potentials, Face, Female, Humans, Male, Middle Aged, Neural Pathways, Photic Stimulation, Time Factors, Video Recording, Young Adult
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