Cited by 357Genomics and Phylogenetic StudiesPhotosynthetic Processes and MechanismsBacterial Genetics and Biotechnology

Complete Genome Structure of the Thermophilic Cyanobacterium Thermosynechococcus elongatus BP-1

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Nakamura, Y.·2002·DNA Research

Abstract

The entire genome of a thermophilic unicellular cyanobacterium, Thermosynechococcus elongatus BP-1, was sequenced. The genome consisted of a circular chromosome 2,593,857 bp long, and no plasmid was detected. A total of 2475 potential protein-encoding genes, one set of rRNA genes, 42 tRNA genes representing 42 tRNA species and 4 genes for small structural RNAs were assigned to the chromosome by similarity search and computer prediction. The translated products of 56% of the potential protein-encoding genes showed sequence similarity to experimentally identified and predicted proteins of known function, and the products of 34% of these genes showed sequence similarity to the translated products of hypothetical genes. The remaining 10% lacked significant similarity to genes for predicted proteins in the public DNA databases. Sixty-three percent of the T. elongatus genes showed significant sequence similarity to those of both Synechocystis sp. PCC 6803 and Anabaena sp. PCC 7120, while 22% of the genes were unique to this species, indicating a high degree of divergence of the gene information among cyanobacterial strains. The lack of genes for typical fatty acid desaturases and the presence of more genes for heat-shock proteins in comparison with other mesophilic cyanobacteria may be genomic features of thermophilic strains. A remarkable feature of the genome is the presence of 28 copies of group II introns, 8 of which contained a presumptive gene for maturase/reverse transcriptase. A trace of genome rearrangement mediated by the group II introns was also observed.

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Crossref · 10.1093/dnares/9.4.123

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Authors
Nakamura, Y.
Affiliations
Kazusa DNA Research Institute (JP)
Corresponding author
Nakamura, Y.
Venue
DNA Research
Published
2002-01-01
Volume
9
Issue
4
Pages
123-130
ISSN
1340-2838 (ISSN-L)
OpenAlex
W2132582054
Cited by
352
References
32
Citations by year
2026: 3 · 2025: 4 · 2024: 7 · 2023: 12 · 2022: 10 · 2021: 4 · 2020: 13 · 2019: 6 · 2018: 7 · 2017: 12 · 2016: 13 · 2015: 9 · 2014: 15 · 2013: 20 · 2012: 18
FWCI
11.01
Type
journal article
Language
en
Open access
Locations
  • DNA Research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Photosynthetic Processes and Mechanisms
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
Keywords
Thermosynechococcus elongatus BP-1, thermophilic cyanobacteria, complete genome sequence, gene prediction, group II introns, genome rearrangement, heat shock proteins, Synechocystis sp. PCC 6803, Anabaena sp. PCC 7120
MeSH terms
Cyanobacteria, Molecular Sequence Data, Photosynthesis, Genome, Bacterial, Sequence Analysis, DNA

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