Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 1,212

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Intestinal polyposis in mice with a dominant stable mutation of the beta -catenin gene

Open access
Harada, N.·1999·The EMBO Journal
DOI 10.1093/emboj/18.21.5931
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1093/emboj/18.21.5931

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Research works printed but not linked: 48

  1. Aberle H, Bauer A, Stappert J, Kispert A and Kemler R (1997) β‐catenin is a target for the ubiquitin‐proteasome pathway. EMBO J, 16, 3797–3804. · DOI · Paper page
  2. Barth AIM, Pollack AL, Altschuler Y, Mostov KE and Nelson WJ (1997) NH2‐terminal deletion of β‐catenin results in stable colocalization of mutant β‐catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion. J Cell Biol, 136, 693–706. · DOI
  3. Behrens J, Jerchow B‐A, Würtele M, Grimm J, Asbrand C, Wirtz R, Kühl M, Wedlich D and Birchmeier W (1998) Functional interaction of an axin homolog, conductin, with β‐catenin, APC and GSK3β. Science, 280, 596–599. · DOI · Paper page
  4. Ben‐Ze'ev A and Geiger B (1998) Differential molecular interactions of β‐catenin and plakoglobin in adhesion, signaling and cancer. Curr Opin Cell Biol, 10, 629–639. · DOI · Paper page
  5. Cadigan KM and Nusse R (1997) Wnt signaling: a common theme in animal development. Genes Dev, 11, 3286–3305. · DOI · Paper page
  6. de la Coste A et al. (1998) Somatic mutations of the β‐catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc Natl Acad Sci USA, 95, 8847–8851. · DOI · Paper page
  7. Garcia‐Rostan G, Tallini G, Herrero A, D'Aquila TG, Carcangiu ML and Rimm DL (1999) Frequent mutation and nuclear localization of β‐catenin in anaplastic thyroid carcinoma. Cancer Res, 59, 1811–1815.
  8. Gat U, DasGupta R, Degenstein L and Fuchs E (1998) De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated β‐catenin in skin. Cell, 95, 605–614. · DOI · Paper page
  9. Haegel H, Larue L, Ohsugi M, Fedorov L, Herrenkecht K and Kemler R (1995) Lack of β‐catenin affects mouse development at gastrulation. Development, 121, 3529–3537. · DOI · Paper page
  10. Hart MH, de los Santos R, Albert IN, Runinfeld B and Polakis P (1998) Downregulation of β‐catenin by human axin and its association with the APC tumor suppressor, β‐catenin and GSK3β. Curr Biol, 8, 573–581. · DOI · Paper page
  11. Huber O, Korn R, McLaughlin J, Ohsugi M, Herrmann BG and Kemler R (1996) Nuclear localization of β‐catenin by interaction with transcription factor LEF‐1. Mech Dev, 59, 3–10. · DOI · Paper page
  12. Ichinose Y, Hashido K, Miyamoto H, Nagata T, Nozaki M, Morita T and Matsushiro A (1989) Molecular cloning and characterization of cDNA encoding mouse cytokeratin No. 19. Gene, 80, 315–323. · DOI
  13. Iwao K, Nakamori S, Kameyama M, Imalka S, Kinoshita M, Fukui T, Ishiguro S, Nakamura Y and Miyoshi Y (1998) Activation of the β‐catenin gene by interstitial deletions involving exon 3 in primary colorectal carcinomas without adenomatous polyposis coli mutations. Cancer Res, 58, 1021–1026.
  14. Kemler R (1993) From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet, 9, 317–321. · DOI · Paper page
  15. Kozak M (1987) An analysis of 5′‐noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res, 15, 8125–8148. · DOI · Paper page
  16. Miyoshi Y, Iwao K, Nagakawa Y, Aihara T, Sasaki Y, Imaoa S, Murata M, Shimano T and Nakamura Y (1998) Activation of the β‐catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3. Cancer Res, 58, 2524–2527.
  17. Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B and Kinzler KW (1997) Activation of β‐catenin‐Tcf signaling in colon cancer by mutations in β‐catenin or APC. Science, 275, 1787–1790. · DOI · Paper page
  18. Moser AR, Shoemaker AR, Connely CS, Clipson L, Gould KA, Luongo C, Dove WF, Siggers PH and Gardner R (1995) Homozygosity for the Min allele of Apc results in disruption of mouse development prior to gastrulation. Dev Dyn, 203, 422–433. · DOI
  19. Munemitsu S, Albert I, Souza B, Rubinfeld B and Polakis P (1995) Regulation of intracellular β‐catenin levels by the adenomatous polyposis coli (APC) tumor‐suppressor protein. Proc Natl Acad Sci USA, 92, 3046–3050. · DOI · Paper page
  20. Näthke IS, Adams CL, Polakis P, Sellin JH and Nelson WJ (1996) The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration. J Cell Biol, 134, 165–178. · DOI · Paper page
  21. Neufeld KL and White RL (1997) Nuclear and cytoplasmic localization of the adenomatous polyposis coli protein. Proc Natl Acad Sci USA, 94, 3034–3039. · DOI
  22. Nusse R and Varmus H (1982) Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell, 31, 99–109. · DOI · Paper page
  23. Ogawa K, Yamada Y, Kishibe K, Ishizaki K and Tokusashi Y (1999) β‐catenin mutations are frequent in hepatocellular carcinomas but absent in adenomas induced by diethylnitrosamine in B6C3F1 mice. Cancer Res, 59, 1830–1833.
  24. Oshima H, Oshima M, Kobayashi M, Tsutsumi M and Taketo MM (1997) Morphological and molecular processes of polyp formation in ApcΔ716 knockout mice. Cancer Res, 57, 1644–1649.
  25. Oshima M, Oshima H, Kitagawa K, Kobayashi M, Itakura C and Taketo M (1995) Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. Proc Natl Acad Sci USA, 92, 4482–4486. · DOI · Paper page
  26. Oshima M, Dinchuck JE, Kargman SL, Oshima H, Hancock B, Kwong E, Trzaskos JM, Evans JE and Taketo MM (1996) Suppression of intestinal polyposis in ApcΔ716 knockout mice by inhibition of cyclooxygenase 2 (COX‐2). Cell, 87, 803–809. · DOI · Paper page
  27. Polakis P (1999) The oncogenic activation of β‐catenin. Curr Opin Genet Dev, 9, 15–21. · DOI · Paper page
  28. Quaroni A, Calnek D, Quaroni E and Chandler JS (1991) Keratin expression in rat intestinal crypt and villus cells. J Biol Chem, 266, 11923–11931. · DOI
  29. Rubinfeld B, Sousa B, Albert B, Müller O, Chamberlain SH, Masiarz FR, Munemitsu S and Polakis P (1993) Association of the APC gene product with β‐catenin. Science, 262, 1731–1734. · DOI · Paper page
  30. Rubinfeld B, Albert I, Porfiri E, Fiol C, Munemitsu S and Polakis P (1996) Binding of GSK3β to the APC–β‐catenin complex and regulation of complex assembly. Science, 272, 1023–1026. · DOI · Paper page
  31. Rubinfeld B, Robbins P, El‐Gami M, Albert I, Porfiri E and Polakis P (1997) Stabilization of β‐catenin by genetic defects in melanoma cell lines. Science, 275, 1790–1792. · DOI · Paper page
  32. Sakanaka C, Weiss JB and Williams LT (1998) Bridging of β‐catenin and glycogen synthase kinase‐3β by axin and inhibition of β‐catenin‐mediated transcription. Proc Natl Acad Sci USA, 95, 3020–3023. · DOI · Paper page
  33. Sauer B (1993) Manipulation of transgenes by site‐specific recombination: use of Cre recombinase. Methods Enzymol, 225, 890–900. · DOI · Paper page
  34. Schmidt GH, Winton DJ and Ponder BA (1988) Development of the pattern of cell renewal in the crypt‐villus unit of chimaeric mouse small intestine. Development, 103, 785–790. · DOI
  35. Shull MM et al. (1992) Targeted disruption of the mouse transforming growth factor‐β1 gene results in multifocal inflammatory disease. Nature, 359, 693–699. · DOI · Paper page
  36. Simon TC, Roth KA and Gordon JI (1993) Use of transgenic mice to map cis‐acting elements in the liver fatty acid‐binding protein gene (Fabpl) that regulate its cell lineage‐specific, differentiation‐dependent and spatial patterns of expression in the gut epithelium and in the liver acinus. J Biol Chem, 268, 18345–18358. · DOI
  37. Soriano P, Montgomery C, Geske R and Bradley A (1991) Targeted disruption of the c‐src proto‐oncogene leads to osteopetrosis in mice. Cell, 64, 693–702. · DOI · Paper page
  38. Sparks AB, Morin PJ, Vogelstein B and Kinzler KW (1998) Mutational analysis of the APC/β‐catenin/Tcf pathway in colorectal cancer. Cancer Res, 58, 1130–1134.
  39. Su LK, Vogelstein B and Kinzler KW (1993) Association of the APC tumor suppressor protein with catenins. Science, 262, 1734–1737. · DOI · Paper page
  40. Sweetser DA, Birkenmeier EH, Hoppe PC, McKeel DW and Gordon JI (1988) Mechanisms underlying generation of gradients in gene expression within the intestine: an analysis using transgenic mice containing fatty acid binding protein–human growth hormone fusion genes. Genes Dev, 2, 1318–1332. · DOI
  41. Takaku K, Oshima M, Miyoshi H, Matsui M, Seldin MF and Taketo MM (1998) Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell, 92, 645–656. · DOI · Paper page
  42. Voeller HJ, Truica CI and Gelman EP (1998) β‐catenin mutations in human prostate cancer. Cancer Res, 58, 2520–2523.
  43. Wodarz A and Nusse R (1998) Mechanisms of Wnt signaling in development. Annu Rev Cell Dev Biol, 14, 59–88. · DOI · Paper page
  44. Wong MH, Rubinfeld B and Gordon JI (1998) Effects of forced expression of an NH2‐terminal truncated β‐catenin on mouse intestinal epithelial homeostasis. J Cell Biol, 141, 765–767. · DOI
  45. Yost C, Torres M, Miller JR, Huang E, Kimelman D and Moon RT (1996) The axis‐inducing activity, stability and subcellular distribution of β‐catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. Genes Dev, 10, 1443–1454. · DOI · Paper page
  46. Yu X and Bienz M (1999) Ubiquitous expression of a Drosophila adenomatous polyposis coli homolog and its localization in cortical actin caps. Mech Dev, 84, 69–73. · DOI
  47. Zeng L et al. (1997) The mouse Fused locus encodes axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation. Cell, 90, 181–192. · DOI · Paper page
  48. Zurawel RH, Chiappa SA, Allen C and Raffel C (1998) Sporadic medulloblastomas contain oncogenic β‐catenin mutations. Cancer Res, 58, 896–899.

Cited by

See all 1,212

Metadata

Authors
Harada, N.
Venue
The EMBO Journal
Publisher
Springer Science and Business Media LLC
Published
1999-11-01
Volume
18
Issue
21
Pages
5931-5942
ISSN
  • 0261-4189 (ISSN-L)
  • 1460-2075
DOI
10.1093/emboj/18.21.5931
OpenAlex
W2090863421
Cited by
1,212
References
2
FWCI
7.39
Type
journal article
Language
en
Open access
bronze
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.