Cited by 2,019Cardiac pacing and defibrillation studiesCardiac Arrest and ResuscitationCardiac electrophysiology and arrhythmias

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2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy

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Glikson, Michael, Nielsen, Jens Cosedis, Kronborg, Mads Brix, Michowitz, Yoav, Auricchio, Angelo, Barbash, Israel Moshe, Barrabés, José A, Boriani, Giuseppe, Braunschweig, Frieder, Brignole, Michele, Burri, Haran, Coats, Andrew J S, Deharo, Jean-Claude, Delgado, Victoria, Diller, Gerhard-Paul, Israel, Carsten W, Keren, Andre, Knops, Reinoud E, Kotecha, Dipak, Leclercq, Christophe, Merkely, Béla, Starck, Christoph, Thylén, Ingela, Tolosana, José Maria, ESC Scientific Document Group, Leyva, Francisco, Linde, Cecilia, Abdelhamid, Magdy, Aboyans, Victor, Arbelo, Elena, Asteggiano, Riccardo, Barón-Esquivias, Gonzalo, Bauersachs, Johann, Biffi, Mauro, Birgersdotter-Green, Ulrika, Bongiorni, Maria Grazia, Borger, Michael A, Čelutkienė, Jelena, Cikes, Maja, Daubert, Jean-Claude, Drossart, Inga, Ellenbogen, Kenneth, Elliott, Perry M, Fabritz, Larissa, Falk, Volkmar, Fauchier, Laurent, Fernández-Avilés, Francisco, Foldager, Dan, Gadler, Fredrik, De Vinuesa, Pastora Gallego Garcia, Gorenek, Bulent, Guerra, Jose M, Hermann Haugaa, Kristina, Hendriks, Jeroen, Kahan, Thomas, Katus, Hugo A, Konradi, Aleksandra, Koskinas, Konstantinos C, Law, Hannah, Lewis, Basil S, Linker, Nicholas John, Løchen, Maja-Lisa, Lumens, Joost, Mascherbauer, Julia, Mullens, Wilfried, Nagy, Klaudia Vivien, Prescott, Eva, Raatikainen, Pekka, Rakisheva, Amina, Reichlin, Tobias, Ricci, Renato Pietro, Shlyakhto, Evgeny, Sitges, Marta, Sousa-Uva, Miguel, Sutton, Richard, Suwalski, Piotr, Svendsen, Jesper Hastrup, Touyz, Rhian M, Van Gelder, Isabelle C, Vernooy, Kevin, Waltenberger, Johannes, Whinnett, Zachary, Witte, Klaus K, Kronborg, Mads Brix, Michowitz, Yoav, Auricchio, Angelo, Barbash, Israel Moshe, Barrabés, José A, Boriani, Giuseppe, Braunschweig, Frieder, Brignole, Michele, Burri, Haran, Coats, Andrew J S, Deharo, Jean-Claude, Delgado, Victoria, Diller, Gerhard-Paul, Israel, Carsten W, Keren, Andre, Knops, Reinoud E, Kotecha, Dipak, Leclercq, Christophe, Merkely, Béla, Starck, Christoph, Thylén, Ingela, Tolosana, José Maria·2021·European Heart Journal

DOI 10.1093/eurheartj/ehab364

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Abstract

The ESC Guidelines represent the views of the ESC and were produced after careful consideration of the scientific and medical knowledge and the evidence available at the time of their publication.The ESC is not responsible in the event of any contradiction, discrepancy, and/or ambiguity between the ESC Guidelines and any other official recommendations or guidelines issued by the relevant public health authorities, in particular in relation to good use of healthcare or therapeutic strategies.Health professionals are encouraged to take the ESC Guidelines fully into account when exercising their clinical judgement, as well as in the determination and the implementation of preventive, diagnostic, or therapeutic medical strategies; however, the ESC Guidelines do not override, in any way whatsoever, the individual responsibility of health professionals to make appropriate and accurate decisions in consideration of each patient's health condition and in consultation with that patient and, where appropriate and/or necessary, the patient's caregiver.Nor do the ESC Guidelines exempt health professionals from taking into full and careful consideration the relevant official updated recommendations or guidelines issued by the competent public health authorities, in order to manage each patient's case in light of the scientifically accepted data pursuant to their respective ethical and professional obligations.It is also the health professional's responsibility to verify the applicable rules and regulations relating to drugs and medical devices at the time of prescription.

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Cardiovascular involvement in systemic lupus erythematosus
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Long term performance and safety of His bundle pacing: A multicenter experience
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Scar Characterization to Predict Life-Threatening Arrhythmic Events and Sudden Cardiac Death in Patients With Cardiac Resynchronization Therapy
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Cardiac rhythm disturbances early after orthotopic heart transplantation: Prevalence and clinical importance of the observed abnormalities
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Arrhythmic Burden as Determined by Ambulatory Continuous Cardiac Monitoring in Patients With New-Onset Persistent Left Bundle Branch Block Following Transcatheter Aortic Valve Replacement
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The national heart failure audit for England and Wales 2008–2009
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Syncope Due to Idiopathic Paroxysmal Atrioventricular Block
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Atrial antitachycardia pacing and managed ventricular pacing in bradycardia patients with paroxysmal or persistent atrial tachyarrhythmias: the MINERVA randomized multicentre international trial
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The Natural History of Primary First-Degree Atrioventricular Heart Block
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High incidence of pacemaker syndrome in patients with sinus node dysfunction treated with ventricular-based pacing in the Mode Selection Trial (MOST)
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Results and complications of the carotid sinus massage performed according to the “method of symptoms”
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Cardiac surgery: Postoperative arrhythmias
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NONSURGICAL ACQUIRED HEART BLOCK*
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The Conduction System in Acute Myocardial Infarction Complicated by Heart Block
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Rate, causes, and impact on patient outcome of implantable device complications requiring surgical revision: large population survey from two centres in Italy
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High-degree atrioventricular block complicating ST-segment elevation myocardial infarction in the era of primary percutaneous coronary intervention
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Efficacy of atrial antitachycardia pacing using the Medtronic AT500 pacemaker in patients with congenital heart disease
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Upgrading from Single Chamber Right Ventricular to Biventricular Pacing in Permanently Paced Patients with Worsening Heart Failure: The RD‐CHF Study
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Predictors and Course of High-Degree Atrioventricular Block After Transcatheter Aortic Valve Implantation Using the CoreValve Revalving system
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Individual patient data network meta-analysis of mortality effects of implantable cardiac devices
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Meta-analysis: Cardiac Resynchronization Therapy for Patients With Less Symptomatic Heart Failure
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Prevalence and Natural History of Heart Disease in Adults with Primary Mitochondrial Respiratory Chain Disease
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Electrophysiologic testing in bundle branch block and unexplained syncope
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Complications of Permanent Transvenous Cardiac Pacing: A 14‐Year Review of all Transvenous Pacemakers Inserted at One Community Hospital
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Outcome of Cardiac Sarcoidosis Presenting With High-Grade Atrioventricular Block
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The Significance of Second Degree Atrioventricular Block and Bundle Branch Block
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Preventing Ventricular Dysfunction in Pacemaker Patients without Advanced Heart Failure: Results from a Multicentre International Randomized Trial (PREVENT-HF)
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CRT Survey II: A European Society of Cardiology Survey of Cardiac Resynchronisation Therapy in 11 088 Patients—Who is doing what to whom and How?
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HRS/ACC/AHA Expert Consensus Statement on the Use of Implantable Cardioverter-Defibrillator Therapy in Patients Who Are Not Included or Not Well Represented in Clinical Trials
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Recommendations for participation in leisure-time physical activity and competitive sports in patients with arrhythmias and potentially arrhythmogenic conditions Part I: Supraventricular arrhythmias and pacemakers
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Prospective multicentre systematic guideline-based management of patients referred to the Syncope Units of general hospitals
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Electrophysiologic evaluation of sinus node function and atrioventricular conduction in patients with prolonged ventricular asystole during obstructive sleep apnea
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Randomized trial of pacemaker and lead system for safe scanning at 1.5 Tesla
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Natural history of chronic second-degree atrioventricular nodal block
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Neurally mediated syncope detected by carotid sinus massage and head-up tilt test in sick sinus syndrome
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Trends of Cardiovascular Implantable Electronic Device Infection in 3 Decades
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Chronic pacing and adverse outcomes after transcatheter aortic valve implantation
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Dual-Chamber Pacing With Closed Loop Stimulation in Recurrent Reflex Vasovagal Syncope
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Reversal of Pacing-Induced Cardiomyopathy Following Cardiac Resynchronization Therapy
Khurshid, S. S., Obeng-Gyimah, E. K., Supple, G. E., Schaller, R. D., Lin, D., OWENS, A. T., Epstein, A. E., Dixit, S., Marchlinski, F. E., & Frankel, D. S. (2017) · JACC. Clinical electrophysiology · doi:10.1016/j.jacep.2017.10.002 · Cited by 131
Quality of Care in the United Kingdom after Removal of Financial Incentives
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The Efficacy of His Bundle Pacing: Lessons Learned From Implementation for the First Time at an Experienced Electrophysiology Center
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DDD pacing in hypertrophic cardiomyopathy: a multicentre clinical experience.
Slade, A., Sadoul, N., Shapiro, L. M., Chojnowska, L., Simon, J.-P., Saumarez, R. C., Dodinot, B., Camm, A. J., McKenna, W. J., & Aliot, E. (1996) · Heart · doi:10.1136/hrt.75.1.44 · Cited by 129
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Twenty-eight years of research permit reinterpretation of tilt-testing: hypotensive susceptibility rather than diagnosis
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Arrhythmias in the muscular dystrophies
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Phrenic Stimulation
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Multimodality Imaging-Guided Left Ventricular Lead Placement in Cardiac Resynchronization Therapy: A Randomized Controlled Trial
Sommer, A., Kronborg, M. B., Nørgaard, B. L., Poulsen, S. H., Bouchelouche, K., Bøttcher, M., Jensen, H. K., Jensen, J. M., Kristensen, J., Gerdes, C., et al. (2016) · European Journal of Heart Failure · doi:10.1002/ejhf.530 · Cited by 127
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Impact of Leadless Pacemaker Therapy on Cardiac and Atrioventricular Valve Function Through 12 Months of Follow-Up
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“B ‐ blockers, nondihydropyridine calcium channel blockers (non ‐ DHP CCBs), class Ic/III antiarrhythmics, and digoxin have been considered reversible causes of AVB in clinical practice [2 – 4].”
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Authors: Glikson, M., Nielsen, J. C., Kronborg, M. B., Michowitz, Y., Auricchio, A., Barbash, I. M., Barrabés, J. A., Boriani, G., Braunschweig, F., Brignole, M., Burri, H., Coats, A. J. S., Deharo, J.-C., Delgado, V., Diller, G.-P., Israel, C. W., Keren, A., Knops, R. E., Kotecha, D., Leclercq, C., Merkely, B., Starck, C., Thylén, I., Tolosana, J. M., ESC Scientific Document Group, Leyva, F., Linde, C., Abdelhamid, M., Aboyans, V., Arbelo, E., Asteggiano, R., Barón-Esquivias, G., Bauersachs, J., Biffi, M., Birgersdotter-Green, U., Bongiorni, M. G., Borger, M. A., Čelutkienė, J., Cikes, M., Daubert, J.-C., Drossart, I., Ellenbogen, K., Elliott, P. M., Fabritz, L., Falk, V., Fauchier, L., Fernández-Avilés, F., Foldager, D., Gadler, F., De Vinuesa, P. G. G., Gorenek, B., Guerra, J. M., Hermann Haugaa, K., Hendriks, J., Kahan, T., Katus, H. A., Konradi, A., Koskinas, K. C., Law, H., Lewis, B. S., Linker, N. J., Løchen, M.-L., Lumens, J., Mascherbauer, J., Mullens, W., Nagy, K. V., Prescott, E., Raatikainen, P., Rakisheva, A., Reichlin, T., Ricci, R. P., Shlyakhto, E., Sitges, M., Sousa-Uva, M., Sutton, R., Suwalski, P., Svendsen, J. H., Touyz, R. M., Van Gelder, I. C., Vernooy, K., Waltenberger, J., Whinnett, Z., Witte, K. K., Kronborg, M. B., Michowitz, Y., Auricchio, A., Barbash, I. M., Barrabés, J. A., Boriani, G., Braunschweig, F., Brignole, M., Burri, H., Coats, A. J. S., Deharo, J.-C., Delgado, V., Diller, G.-P., Israel, C. W., Keren, A., Knops, R. E., Kotecha, D., Leclercq, C., Merkely, B., Starck, C., Thylén, I., & Tolosana, J. M.
Affiliations: Aarhus University (DK)
ORCID: Glikson, Michael
Nielsen, Jens Cosedis
Abdelhamid, Magdy
Aboyans, Victor
Asteggiano, Riccardo
Čelutkienė, Jelena
Daubert, Jean-Claude
Ellenbogen, Kenneth
Falk, Volkmar
Fauchier, Laurent
Hendriks, Jeroen
Kahan, Thomas
Katus, Hugo A
Koskinas, Konstantinos C
Lumens, Joost
Prescott, Eva
Ricci, Renato Pietro
Sutton, Richard
Vernooy, Kevin
Witte, Klaus K
Venue: European Heart Journal
Publisher: Oxford University Press (OUP)
Published: 2021-08-29
Volume: 42
Issue: 35
Pages: 3427-3520
ISSN: 0195-668X (ISSN-L)
1522-9645
DOI: 10.1093/eurheartj/ehab364
OpenAlex: W3217576295
Cited by: 2,019
References: 859
Citations by year: 2026: 358 · 2025: 391 · 2024: 413 · 2023: 428 · 2022: 378 · 2021: 46
FWCI: 211.76
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
Locations: European Heart Journal (publishedVersion)
Research Publications (Maastricht University) (publishedVersion, other-oa)
Pure Amsterdam UMC (publishedVersion, other-oa)
Leiden Repository (Leiden University) (submittedVersion, cc-by)
Data Archiving and Networked Services (DANS) (submittedVersion)
Data Archiving and Networked Services (DANS) (submittedVersion, cc-by)
IRIS UNIMORE (University of Modena and Reggio Emilia) (submittedVersion, cc-by)
University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
Scopus (Elsevier) (submittedVersion)
Radboud Repository (Radboud University) (submittedVersion)
Funders: Sociedad Española de Cardiología
British Cardiovascular Society
National Institute for Health and Care Research (NIHR200158, NIHR130280)
Türk Kardiyoloji Derneği
Novo Nordisk Fonden (NNF16OC0018658)
Slovenská Kardiologická Spoločnost
Sociedade Portuguesa de Cardiologia
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Health Sciences › Medicine › Emergency Medicine › Cardiac Arrest and Resuscitation
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Keywords: cardiac pacing, cardiac resynchronization therapy, pacing indications, heart failure, atrial fibrillation

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2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy

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