The DOI matches its Crossref record; 37 of the 40 references it cites were found in a registry or an index.
High blood pressure response to exercise predicts future development of hypertension in young athletes
Open accessAbstract
Aims: Due to superior exercise performance, athletes show higher blood pressure (BP) at peak exercise compared to untrained individuals. Thus, higher reference values for peak exercise systolic and diastolic BP were reported specifically for athletes. However, the prognostic significance of high blood pressure response (HBPR) to exercise has not yet been clarified in this population. Methods and results: One hundred and forty-one normotensive athletes with HBPR to exercise were compared to 141 normotensive athletes with normal blood pressure response (NBPR) to exercise, matched for gender, age, body size, and type of sport. All athletes were followed up for 6.5 ± 2.8 years. Over follow-up, no cardiac events occurred; 24 athletes were diagnosed essential hypertension (8.5%). Specifically, 19 (13.5%) belonged to the HBPR compared with 5 (3.5%) in the NBPR group (P = 0.003). Kaplan-Meier analysis confirmed that the incidence of hypertension during follow-up was higher in the HBPR group (log-rank χ2P-value = 0.009). Multivariable analysis by Cox proportional hazard survival model showed that resting BP and HBPR at baseline evaluation were the strongest predictors of incident hypertension (χ2 for the model 30.099; P < 0.001). Specifically, HBPR was associated with a hazard ratio of 3.6 (95% confidence interval 1.3-9.9) of developing hypertension. Over follow-up exercise capacity, as well as morphologic and functional cardiac parameters in athletes from both groups did not change significantly. Conclusion: The present study showed that an exaggerated BP response to exercise increased the risk for incident hypertension in highly trained and normotensive athletes over a middle-term period.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Notably, exaggerated exercising BP responses, particularly to submaximal exercise [19, 20], are a robust, independent predictor of future hypertension [21–23] and cardiovascular (CV) morbidity and mortality [20, 24, 25].”
From Habitual preexercise caffeine supplementation prevents exercise training-induced attenuation of exercising systolic blood pressure and double product (2025) · cites this paper as [21]
The cited source says what the claim attributes to it.
In the citing paper
“A hypertensive BP response during exercise is an independent predictor of hypertension, regardless of resting BP levels in the general population29 and among athletes.30”
From Resting and exercise-induced occult hypertension and coronary atherosclerosis in male masters endurance athletes (2026) · cites this paper as [30]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
2013 ESH/ESC Guidelines for the management of arterial hypertension
Authors Task Force Members, Mancia, G., Fagard, R., Narkiewicz, K., Redon, J., Zanchetti, A., Böhm, M., Christiaens, T., Cífková, R., Backer, G. D., et al. (2013) · European Heart Journal · doi:10.1093/eurheartj/eht151 · Cited by 13,739
Lang, R. M., Badano, L. P., Mor-Avi, V., Afilalo, J., Armstrong, A., Ernande, L., Flachskampf, F. A., Foster, E., Goldstein, S. A., Kuznetsova, T., et al. (2015) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2014.10.003 · Cited by 12,362
2018 ESC/ESH Guidelines for the management of arterial hypertension
Williams, B., Mancia, G., Spiering, W., Agabiti Rosei, E., Azizi, M., Burnier, M., Clement, D. L., Coca, A., de Simone, G., Dominiczak, A., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy339 · Cited by 10,286
Lang, R. M., Badano, L. P., Mor‐Avi, V., Afilalo, J., Armstrong, A. D. C., Ernande, L., Flachskampf, F. A., Foster, E., Goldstein, S. A., Kuznetsova, T., et al. (2015) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jev014 · Cited by 8,630
European Guidelines on cardiovascular disease prevention in clinical practice (version 2012)
Authors/Task Force Members:, Perk, J., De Backer, G., Gohlke, H., Graham, I., Reiner, Ž., Verschuren, M., Albus, C., Benlian, P., Boysen, G., et al. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehs092 · Cited by 8,490
2016 European Guidelines on cardiovascular disease prevention in clinical practice
Piepoli, M. F., Hoes, A. W., Agewall, S., Albus, C., Brotons, C., Catapano, A. L., Cooney, M.-T., Corrà, U., Cosyns, B., Deaton, C., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw106 · Cited by 6,457
Williams, B., Mancia, G., Spiering, W., Agabiti Rosei, E., Azizi, M., Burnier, M., Clement, D. L., Coca, A., de Simone, G., Dominiczak, A., et al. (2018) · Journal of Hypertension · doi:10.1097/hjh.0000000000001940 · Cited by 2,885
ACC/AHA 2002 Guideline Update for Exercise Testing: Summary Article
Gibbons, R. J., Balady, G. J., Bricker, J. T., CHAITMAN, B. R., Fletcher, G. F., Froelicher, V. F., Mark, D. B., McCallister, B. D., Mooss, A. N., O’Reilly, M. G., et al. (2002) · Circulation · doi:10.1161/01.cir.0000034670.06526.15 · Cited by 2,583
Mancia, G., Fagard, R., Narkiewicz, K., Redón, J., Zanchetti, A., Böhm, M., Christiaens, T., Cifkova, R., Backer, G. D., Dominiczak, A. F., et al. (2013) · Open Access CRIS of the University of Bern · doi:10.7892/boris.41664 · Cited by 742
Blood Pressure Response During Treadmill Testing as a Risk Factor for New-Onset Hypertension
Singh, J. P., Larson, M. G., Manolio, T. A., O’Donnell, C. J., Lauer, M. S., Evans, J. C., & Levy, D. A. (1999) · Circulation · doi:10.1161/01.cir.99.14.1831 · Cited by 460
Piepoli, M. F., Hoes, A. W., Agewall, S., Albus, C., Brotons, C., Catapano, A. L., Cooney, M.-T., Corrà, U., Cosyns, B., Deaton, C., et al. (2016) · Open Access CRIS of the University of Bern · doi:10.7892/boris.89711 · Cited by 408
Pelliccia, A., Caselli, S., Sharma, S., Basso, C., Bax, J. J., Corrado, D., D’Andrea, A., D’Ascenzi, F., Paolo, F. M. D., Edvardsen, T., et al. (2017) · European Heart Journal · doi:10.1093/eurheartj/ehx532 · Cited by 380
Self-citationSchultz, M. G., Otahal, P., Cleland, V. J., Blizzard, L., Marwick, T. H., & Sharman, J. E. (2013) · American Journal of Hypertension · doi:10.1093/ajh/hps053 · Cited by 306
Olivotto, I., Maron, B. J., Montereggi, A., Mazzuoli, F., Dolara, A., & Cecchi, F. (1999) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(99)00094-7 · Cited by 254
Exaggerated exercise blood pressure is related to impaired endothelial vasodilator function
Stewart, K. J. (2004) · American Journal of Hypertension · doi:10.1016/s0895-7061(03)01003-3 · Cited by 210
The blood pressure response to dynamic exercise testing: A systematic review
Le, V.-V., Mitiku, T., Sungar, G., Myers, J., & Froelicher, V. (2008) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2008.07.001 · Cited by 197
Baron, S., Hein, M. J., Lehman, E. J., & Gersic, C. M. (2012) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2011.10.050 · Cited by 190
Task Force 1: Preparticipation screening and diagnosis of cardiovascular disease in athletes
Maron, B. J., Douglas, P. S., Graham, T. P., Nishimura, R. A., & Thompson, P. D. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.02.007 · Cited by 181
Tahir, E., Starekova, J., Muellerleile, K., von Stritzky, A., Münch, J., Avanesov, M., Weinrich, J. M., Stehning, C., Bohnen, S., Radunski, U. K., et al. (2018) · JACC: Cardiovascular Imaging · doi:10.1016/j.jcmg.2017.09.016 · Cited by 168
Prevalence of Cardiovascular Disease Risk Factors Among National Football League Players
TUCKER, A. M. (2009) · JAMA · doi:10.1001/jama.2009.716 · Cited by 159
Lewis, G. D., Gona, P., Larson, M. G., Plehn, J. F., Benjamin, E. J., O'Donnell, C. J., Levy, D., Vasan, R. S., & Wang, T. J. (2008) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2008.01.046 · Cited by 133
Exercise BP response in subjects with high-normal BP
Miyai, N., Arita, M., Morioka, I., Miyashita, K., Nishio, I., & Takeda, S. (2000) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)00903-7 · Cited by 121
Blood Pressure Response to Exercise and Cardiovascular Disease
Schultz, M. G., Gerche, A. L., & Sharman, J. E. (2017) · Current Hypertension Reports · doi:10.1007/s11906-017-0787-1 · Cited by 118
Sharman, J. E., Hare, J. L., Thomas, S., Davies, J. E., Leano, R., Jenkins, C., & Marwick, T. H. (2011) · American Journal of Hypertension · doi:10.1038/ajh.2011.75 · Cited by 108
Bonow, R. O., Nishimura, R. A., Thompson, P. D., & Udelson, J. E. (2015) · Circulation · doi:10.1161/cir.0000000000000241 · Cited by 103
Upper normal values of blood pressure response to exercise in Olympic athletes
Caselli, S., Vaquer-Seguí, A., Quattrini, F. M., Gacinto, B. D., Milan, A., Assorgi, R., Verdile, L., Spataro, A., & Pelliccia, A. (2016) · American Heart Journal · doi:10.1016/j.ahj.2016.04.020 · Cited by 96
Self-citationShim, C. Y., Ha, J., Park, S., Choi, E., Choi, D., Rim, S., & Chung, N. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.03.052 · Cited by 92
Smith, S. C., Jr. (2019) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/ep24-1b87 · Cited by 92
Patterns of Left Ventricular Diastolic Function in Olympic Athletes
Caselli, S., Paolo, F. M. D., Pisicchio, C., Pandian, N. G., & Pelliccia, A. (2014) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2014.09.013 · Cited by 82
Self-citationPelliccia, A., Adami, P. E., Quattrini, F. M., Squeo, M. R., Caselli, S., Verdile, L., Maestrini, V., Paolo, F. M. D., Pisicchio, C., Ciardo, R., et al. (2016) · British Journal of Sports Medicine · doi:10.1136/bjsports-2016-096961 · Cited by 82
Self-citationExercise Blood Pressure and the Risk for Future Hypertension Among Normotensive Middle‐Aged Adults
Berger, A., Grossman, E., Katz, M., Kivity, S., Klempfner, R., Segev, S., Goldenberg, I., Sidi, Y., & Maor, E. (2015) · Journal of the American Heart Association · doi:10.1161/jaha.114.001710 · Cited by 77
Exaggerated Exercise Blood Pressure Response and Future Cardiovascular Disease
Tzemos, N., Lim, P. O., Mackenzie, I. S., & MacDonald, T. M. (2015) · Journal of Clinical Hypertension · doi:10.1111/jch.12629 · Cited by 76
The impact of elevated blood pressure on exercise capacity in elite athletes
Mazic, S. D., Suzic-Lazić, J., Dekleva, M., Antić, M., Soldatović, I., Djelic, M. N., Nešić, D., Aćimović, T., Lazic, M., Lazović, B., et al. (2014) · International Journal of Cardiology · doi:10.1016/j.ijcard.2014.11.125 · Cited by 63
Prevalence and Management of Systemic Hypertension in Athletes.
Caselli, S., Sequì, A. V., Lemme, E., Quattrini, F., Milan, A., D'Ascenzi, F., Spataro, A., & Pelliccia, A. (2017) · American Journal of Cardiology · doi:10.1016/j.amjcard.2017.02.011 · Cited by 51
Self-citationExercise blood pressure and endothelial dysfunction in hypertension
Tzemos, N., Lim, P. O., & MacDonald, T. M. (2009) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2008.01922.x · Cited by 48
Hurst, R. T., Burke, R. F., Wißner, E., Roberts, A. J., Kendall, C. B., Lester, S. J., Somers, V. K., Goldman, M. E., Wu, Q. F., & Khandheria, B. K. (2010) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.12.012 · Cited by 38
PATTERNS OF LEFT VENTRICULAR DIASTOLIC FUNCTION IN OLYMPIC ATHLETES
Caselli, S., Paolo, F. M. D., Giacinto, B. D., Pisicchio, C., Quattrini, F. M., Assorgi, R., Pandian, N. G., & Pelliccia, A. (2014) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(14)61171-2 · Cited by 4
Self-citation
Cited by
Sorted by citations
2020 ESC guidelines on sports cardiology and exercise in patients with cardiovascular disease
Pelliccia, A., Sharma, S., Gati, S., Bäck, M., Börjesson, M., Caselli, S., Collet, J.-P., Corrado, D., Drezner, J. A., Halle, M., et al. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehaa605 · Cited by 1,958
Self-citationBudts, W., Pieles, G. E., Roos‐Hesselink, J. W., la Garza, M. S., D’Ascenzi, F., Giannakoulas, G. A., Müller, J., Oberhoffer, R., Ehringer-Schetitska, D., Herceg-Čavrak, V., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehaa501 · Cited by 156
Self-citationAthlete's Heart: A Cardiovascular Step-By-Step Multimodality Approach
Palermi, S., Cavarretta, E., D’Ascenzi, F., Castelletti, S., Ricci, F., Vecchiato, M., Serio, A., Cavigli, L., Bossone, E., Limongelli, G., et al. (2023) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2405151 · Cited by 84
D’Ascenzi, F., Biella, F., Lemme, E., Maestrini, V., Giacinto, B. D., & Pelliccia, A. (2020) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.120.011587 · Cited by 70
Self-citation2020 ESC Guidelines on Sports Cardiology and Exercise in Patients with Cardiovascular Disease
Pelliccia, A., Sharma, S., Gati, S., Bäck, M., Börjesson, M., Caselli, S., Collet, J., Corrado, D., Drezner, J. A., Halle, M., et al. (2021) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2021.05.003 · Cited by 54
Self-citation
Metadata
- Authors
- Caselli, S., Serdoz, A., Mango, F., Lemme, E., Vaquer Seguì, A., Milan, A., Attenhofer Jost, C., Schmied, C., Spataro, A., & Pelliccia, A.
- Affiliations
- Hirslanden Klinik Im Park (CH)
- Institute of Sports Medicine and Science, Rome, Largo Piero Gabrielli, Roma, Italy
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- Cardiovascular Center Zürich, Hirslanden Klinik im Park, Seestrasse 220, Zürich, Switzerland
- University Heart Center, Rämistrasse 100, Zürich, Switzerland
- Corresponding author
- Caselli, Stefano
- ORCID
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2018-12-22
- Volume
- 40
- Issue
- 1
- Pages
- 62-68
- ISSN
- 0195-668X (ISSN-L)
- 1522-9645
- OpenAlex
- W2906354124
- Cited by
- 109
- References
- 40
- Citations by year
- 2026: 11 · 2025: 6 · 2024: 19 · 2023: 15 · 2022: 16 · 2021: 18 · 2020: 14 · 2019: 10
- FWCI
- 7.93
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- European Heart Journal (publishedVersion)
- PubMed (publishedVersion)
- Institutional Research Information System University of Turin (University of Turin) (submittedVersion, other-oa)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion, other-oa)
- Funders
- Italian National Olympic Committee
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Keywords
- hypertension incidence, youth athletes, essential hypertension, resting blood pressure, exercise capacity, cardiovascular risk prediction
- MeSH terms
- Adult, Blood Pressure, Female, Follow-Up Studies, Humans, Hypertension, Male, Prognosis, Exercise, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
