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Cited by 898

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Cardiovascular disease burden from ambient air pollution in Europe reassessed using novel hazard ratio functions

Open access
Lelieveld, Jos, Klingmüller, Klaus, Pozzer, Andrea, Pöschl, Ulrich, Fnais, Mohammed, Daiber, Andreas, Münzel, Thomas·2019·European Heart Journal

Abstract

Aims: Ambient air pollution is a major health risk, leading to respiratory and cardiovascular mortality. A recent Global Exposure Mortality Model, based on an unmatched number of cohort studies in many countries, provides new hazard ratio functions, calling for re-evaluation of the disease burden. Accordingly, we estimated excess cardiovascular mortality attributed to air pollution in Europe. Methods and results: The new hazard ratio functions have been combined with ambient air pollution exposure data to estimate the impacts in Europe and the 28 countries of the European Union (EU-28). The annual excess mortality rate from ambient air pollution in Europe is 790 000 [95% confidence interval (95% CI) 645 000–934 000], and 659 000 (95% CI 537 000–775 000) in the EU-28. Between 40% and 80% are due to cardiovascular events, which dominate health outcomes. The upper limit includes events attributed to other non-communicable diseases, which are currently not specified. These estimates exceed recent analyses, such as the Global Burden of Disease for 2015, by more than a factor of two. We estimate that air pollution reduces the mean life expectancy in Europe by about 2.2 years with an annual, attributable per capita mortality rate in Europe of 133/100 000 per year. Conclusion: We provide new data based on novel hazard ratio functions suggesting that the health impacts attributable to ambient air pollution in Europe are substantially higher than previously assumed, though subject to considerable uncertainty. Our results imply that replacing fossil fuels by clean, renewable energy sources could substantially reduce the loss of life expectancy from air pollution.

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Metadata

Authors
Lelieveld, J., Klingmüller, K., Pozzer, A., Pöschl, U., Fnais, M., Daiber, A., & Münzel, T.
Venue
European Heart Journal
Published
2019-03-12
Volume
40
Issue
20
Pages
1590-1596
ISSN
  • 0195-668X (ISSN-L)
  • 1522-9645
OpenAlex
W2921829158
Cited by
898
References
7
FWCI
52.03
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Cardiovascular disease burden from ambient air pollution in Europe reassessed using novel hazard ratio functions. https://app.cochat.ai/papers/10.1093/eurheartj/ehz135
The paper
Lelieveld, J., Klingmüller, K., Pozzer, A., Pöschl, U., Fnais, M., Daiber, A., & Münzel, T. (2019). Cardiovascular disease burden from ambient air pollution in Europe reassessed using novel hazard ratio functions. European Heart Journal. https://doi.org/10.1093/eurheartj/ehz135

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