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A Comparison of Leg Power and Leg Strength Within the InCHIANTI Study: Which Influences Mobility More?
Abstract
BACKGROUND: In a clinical study evaluating the functioning of mobility-limited elders, muscle power accounted for more of the variation in function than strength did. There was also evidence that the power-function relationship may be described as curvilinear. However, these findings have never been confirmed in a representative population. METHODS: An analysis was conducted using data from the InCHIANTI study, a population-based cohort of 1032 adults living in Italy. To assess the relationships between impairments in power and strength and mobility performance, we created separate multivariate linear and log-transformed regression models as well as separate logistic regression models. RESULTS: Subjects were age > or = 65 years, predominantly female (54%), with a mean age of 74.2 years, and most had mild-moderate mobility limitations (Short Physical Performance Battery score 10.5 +/- 2.1). Though leg extension power and isometric hip extension strength were closely associated, in several separate multivariate linear regression models, leg power consistently explained more of the variance than strength did in several measures of physical performance. Differences were even larger when observed in curvilinear models of power and strength. Using separate multivariate logistic regression models to examine the odds ratios for mobility limitations in persons with low muscle power versus high muscle power, and in persons with low muscle strength versus high muscle strength, we found that both factors influenced risk for mobility limitations, but low power was associated with a 2-3-fold greater likelihood than low strength. CONCLUSION: These findings identified muscle power to be a more influential proximal determinant of physical performance than impairments in strength and emphasized muscle power as an important determinant of mobility skills in older adults.
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“In a secondary analysis of this study, Bean et al. (6) used multivariate regression models to delineate how the changes in leg power were significantly and independently associated with the clinically meaningful differences observed in SPPB and gait speed.”
From Skeletal Muscle Power: A Critical Determinant of Physical Functioning in Older Adults (2012) · cites this paper as [6]
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“Age-related changes in skeletal muscle size and composition summate to yield reductions in skeletal muscle function (strength and power) [77] that ultimately affect physical performance and the ability to live independently [95].”
From Gut Microbiota Contribute to Age-Related Changes in Skeletal Muscle Size, Composition, and Function: Biological Basis for a Gut-Muscle Axis (2018) · cites this paper as [95]
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Fragala, M. S., Cadore, E. L., Dorgo, S., Izquierdo, M., Kraemer, W. J., Peterson, M. D., & Ryan, E. D. (2019) · Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000003230 · Cited by 1,290
Skeletal Muscle Power: A Critical Determinant of Physical Functioning in Older Adults
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“(9) replicated these observations in a large cohort of 1032 older adults from the Invecchiare in Chianti (InCHIANTI) study and demonstrated that impairments in muscle power were more influential proximal determinants of mobility performance than impairments in muscle strength.”
ResultFunctional Impact of 10 Days of Bed Rest in Healthy Older Adults
Kortebein, P., Symons, T. B., Ferrando, A., Paddon-Jones, D., Ronsen, O., Protas, E., Conger, S., Lombeida, J., Wolfe, R., & Evans, W. J. (2008) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/63.10.1076 · Cited by 550
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Myostatin antibody (LY2495655) in older weak fallers: a proof-of-concept, randomised, phase 2 trial
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Metadata
- Authors
- Bean, J. F., Leveille, S. G., Kiely, D. K., Bandinelli, S., Guralnik, J. M., & Ferrucci, L.
- Affiliations
- Harvard University (US)
- Hebrew SeniorLife (US)
- Istituto Nazionale di Riposo e Cura per Anziani (IT)
- National Institutes of Health (US)
- Venue
- The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-08-01
- Volume
- 58
- Issue
- 8
- Pages
- M728-M733
- ISSN
- 1079-5006 (ISSN-L)
- 1758-535X
- OpenAlex
- W2172236533
- Cited by
- 529
- References
- 29
- Citations by year
- 2026: 25 · 2025: 33 · 2024: 24 · 2023: 19 · 2022: 28 · 2021: 33 · 2020: 33 · 2019: 22 · 2018: 18 · 2017: 34 · 2016: 31 · 2015: 29 · 2014: 29 · 2013: 22 · 2012: 17
- FWCI
- 35.43
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journals of Gerontology Series A (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Hartford Foundation for Public Giving
- National Institute on Aging (K12-AG00294, K12AG000294)
- Topics
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
- Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Keywords
- muscle power, muscle strength, leg extension power, mobility limitations, physical performance, older adults, power function relationship, curvilinear relationship, InCHIANTI cohort
- MeSH terms
- Aged, Female, Humans, Leg, Longitudinal Studies, Male, Muscles, Geriatric Assessment, Walking
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