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Cited by 108Frailty in Older AdultsAging, Health, and DisabilityNutrition and Health in Aging

The DOI matches its Crossref record; 45 of the 46 references it cites were found in a registry or an index.

The Deleterious Effects of Bed Rest Among Community-Living Older Persons

Gill, T. M., Allore, H., Guo, Z.·2004·The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
DOI 10.1093/gerona/59.7.m755
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Abstract

BACKGROUND: Older persons often "take to bed" while they are ill or injured, but relatively little is known about the functional consequences of bed rest among community-living older persons. In this prospective cohort study, the association between episodes of bed rest and functional decline was evaluated during an 18-month period. METHODS: Participants included 680 nondisabled, community-living persons aged 70 years or older. They were separated into 2 groups according to the presence or absence of physical frailty, which was defined based on slow gait speed. Episodes of bed rest were ascertained each month in a telephone interview for a median of 18 months. The completion rate was 99.1%. Functional decline was defined as a worsening in scores between the baseline and 18-month follow-up assessments in 1 or more of the following measures: instrumental activities of daily living, mobility, physical activity, and social activity. RESULTS: Among the 404 (59.4%) participants who had at least 1 episode of bed rest, the mean number of months with bed rest was 2.8 (standard deviation, 2.4). After adjustments were made for several potential confounders, the number of months with bed rest was significantly associated with decline in each of the functional measures. Significant associations were also observed for each of the functional outcomes among participants who were not physically frail, but they were observed only for instrumental activities of daily living disability among participants who were physically frail. CONCLUSIONS: These findings indicate that episodes of bed rest among community-living older persons are associated with decline in several important indicators of function.

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Research works printed but not linked: 4

  1. Creditor, 1993, Annals of Internal Medicine, 118, 219, 10.1001/archinte.153.2.219 · DOI
  2. 2000, Journals of Gerontology Series A: Biological and Medical Sciences, 55A, M221
  3. 1997, Medicine and Science in Sports and Exercise, 29, S123
  4. 1999, Journals of Gerontology Series A: Biological and Medical Sciences, 54A, M377

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Metadata

Authors
Gill, T. M., Allore, H., & Guo, Z.
Affiliations
Yale University (US)
Corresponding author
Gill, T. M.
ORCID
Venue
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
Publisher
Oxford University Press (OUP)
Published
2004-07-01
Volume
59
Issue
7
Pages
M755-M761
ISSN
  • 1079-5006 (ISSN-L)
  • 1758-535X
DOI
10.1093/gerona/59.7.m755
OpenAlex
W2131261325
Cited by
108
References
46
Citations by year
2026: 1 · 2025: 3 · 2024: 7 · 2023: 6 · 2022: 5 · 2021: 5 · 2020: 5 · 2019: 9 · 2018: 6 · 2017: 7 · 2016: 3 · 2015: 3 · 2014: 10 · 2013: 6 · 2012: 3
FWCI
2.61
Type
journal article
Language
en
Open access
closed
Locations
  • The Journals of Gerontology Series A (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Patrick and Catherine Weldon Donaghue Medical Research Foundation
  • Yale University
  • National Institutes of Health (5k23ag000759-02)
  • National Institute on Aging (K24AG021507, R01 AG 17560, K23AG00759, R91 AG 17560)
Topics
  • Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
  • Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
Keywords
bed rest, functional decline, community-dwelling older adults, physical frailty, instrumental activities of daily living, mobility (physical function), physical activity, social activity, walking speed, disability
MeSH terms
Activities of Daily Living, Aged, Aged, 80 and over, Bed Rest, Disability Evaluation, Female, Follow-Up Studies, Humans, Male, Prospective Studies

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