Bone mineral density during long-term use of the progestagen contraceptive implant Implanon® compared to a non-hormonal method of contraception
Abstract
An open, prospective, comparative study was done in healthy women, aged between 18 and 40 years, to study the effects of long-term etonogestrel treatment on bone mineral density (BMD). The control group used a non-hormone-medicated intrauterine device (IUD). The BMD was measured using a dual energy X-ray absorptiometry instrument. Measurements included the lumbar spine (L(2)-L(4)), the proximal femur (femoral neck, Ward's triangle, trochanter) and distal radius. The period of treatment was 2 years and 44 women in the Implanon group and 29 in the IUD group provided data. Groups were comparable at baseline with respect to age, weight, body mass index, BMD and 17beta-oestradiol status. Changes from baseline in BMD in the Implanon group were not essentially different from those in the IUD group. There was no relationship between 17beta-oestradiol concentrations and changes in BMD in this study population. The results of the present study indicate that Implanon((R)) can safely be used in young women who have not yet achieved their peak bone mass.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In a prospective comparative study, changes from baseline in BMD in the ENG implant group were comparable to those in a non-hormone medicated IUS group.
“The effect of ENG-implant on BMD was compared to a non-hormone medicated IUS. Changes from baseline on the ENG-group were comparable from those in the IUS group.”
From Oral and depot progestin therapy for endometriosis: towards a personalized medicine (2017) · cites this paper as [98]
Cites
Marshall, D., Johnell, O., & Wedel, H. (1996) · BMJ · doi:10.1136/bmj.312.7041.1254 · Cited by 3,709 · see citing works
Bone density at various sites for prediction of hip fractures
Cummings, S. R., Browner, W., Cummings, S. R., Black, D. M., Nevitt, M. C., Browner, W., Genant, H. K., Cauley, J., Ensrud, K., Scott, J., et al. (1993) · The Lancet · doi:10.1016/0140-6736(93)92555-8 · Cited by 2,446 · see citing works
Bone density in women receiving depot medroxyprogesterone acetate for contraception.
Cundy, T., Evans, M. C., Roberts, H., Wattie, D. J., Ames, R. W., & Reid, I. R. (1991) · BMJ · doi:10.1136/bmj.303.6793.13 · Cited by 249 · see citing works
Cromer, B. A., Blair, J. M., Mahan, J. D., Zibners, L., & Naumovski, Z. (1996) · The Journal of Pediatrics · doi:10.1016/s0022-3476(96)70148-8 · Cited by 241 · see citing works
Ovarian Function During the Use of a Single Contraceptive Implant: Implanon Compared with Norplant
Mäkäräinen, L., van Beek, A., Tuomivaara, L., Asplund, B., & Bennink, H. J. T. C. (1998) · Fertility and Sterility · doi:10.1016/s0015-0282(98)00015-6 · Cited by 171 · see citing works
Self-citationA multicentre efficacy and safety study of the single contraceptive implant Implanon
Croxatto, H. B. (1999) · Human Reproduction · doi:10.1093/humrep/14.4.976 · Cited by 171 · see citing works
Bone mineral density measured by dual-energy X-ray absorptiometry in healthy finnish women
Laitinen, K., Välimäki, M. J., & Keto, P. E. (1991) · Calcified Tissue International · doi:10.1007/bf02556372 · Cited by 169 · see citing works
Bone mineral density in women using depot medroxyprogesterone acetate for contraception
Scholes, D. (1999) · Obstetrics & Gynecology · doi:10.1016/s0029-7844(98)00447-5 · Cited by 141 · see citing works
Spinal bone density in women using depot medroxyprogesterone contraception*1
CUNDY, T. (1998) · Obstetrics & Gynecology · doi:10.1016/s0029-7844(98)00270-1 · Cited by 117 · see citing works
Naessén, T., Olsson, S.-E., & Gudmundson, J. (1995) · Contraception · doi:10.1016/0010-7824(95)00121-p · Cited by 108 · see citing works
Bone density in long term users of depot medroxyprogesterone acetate
Gbolade, B. A., Ellis, S., Murby, B., Randall, S., & Kirkman, R. (1998) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1998.tb10211.x · Cited by 108 · see citing works
Taneepanichskul, S., Intaraprasert, S., Theppisai, U., & Chaturachinda, K. (1997) · Contraception · doi:10.1016/s0010-7824(97)00116-9 · Cited by 41 · see citing works
Bone Mineral Density in Women Using Depot Medroxyprogesterone Acetate for Contraception
Scholes, D., LaCroix, A. Z., Ott, S. M., et al. (1999) · Obstetrics and Gynecology · doi:10.1097/00006250-199902000-00015 · Cited by 36 · see citing works
Spinal Bone Density in Women Using Depot Medroxyprogesterone Contraception
Cundy, T., Cornish, J., ROBERTS, H., Elder, H., & Reid, I. R. (1998) · Obstetrics and Gynecology · doi:10.1097/00006250-199810000-00016 · Cited by 10 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
U.S. Medical Eligibility Criteria for Contraceptive Use, 2016
Curtis, K. M., Tepper, N. K., Jatlaoui, T. C., Berry-Bibee, E., Horton, L. G., Zapata, L. B., Simmons, K. B., Pagano, H. P., Jamieson, D. J., & Whiteman, M. K. (2016) · MMWR. Recommendations and Reports · doi:10.15585/mmwr.rr6503a1 · Cited by 1,456 · see citing works
Ott, M. A., Sucato, G. S., COMMITTEE ON ADOLESCENCE, Braverman, P. K., Adelman, W. P., Alderman, E. M., Breuner, C. C., Levine, D. A., Marcell, A. V., & O’Brien, R. F. (2014) · PEDIATRICS · doi:10.1542/peds.2014-2300 · Cited by 402 · see citing works
Strategies to prevent unintended pregnancy: increasing use of long-acting reversible contraception
Blumenthal, P. D., Voedisch, A. J., & Gemzell‐Danielsson, K. (2010) · Human Reproduction Update · doi:10.1093/humupd/dmq026 · Cited by 290 · see citing works
U.S. Medical Eligibility Criteria for Contraceptive Use, 2024
Nguyen, A. T., Curtis, K. M., Tepper, N. K., Kortsmit, K., Brittain, A. W., Snyder, E. M., Cohen, M. A., Zapata, L. B., Whiteman, M. K., Contributors, et al. (2024) · MMWR Recommendations and Reports · doi:10.15585/mmwr.rr7304a1 · Cited by 286 · see citing works
Practice Bulletin No. 186: Long-Acting Reversible Contraception: Implants and Intrauterine Devices
(2017) · Obstetrics and Gynecology · doi:10.1097/aog.0000000000002400 · Cited by 191 · see citing works
(2018) · Obstetrics and Gynecology · doi:10.1097/aog.0000000000002632 · Cited by 191 · see citing works
Progestogen-only contraception and bone mineral density: a systematic review
Curtis, K. M., & Martins, S. L. (2006) · Contraception · doi:10.1016/j.contraception.2005.12.010 · Cited by 170 · see citing works
Walch, K., Unfried, G., Huber, J., Kurz, C., van Trotsenburg, M., Pernicka, E., & Wenzl, R. (2009) · Contraception · doi:10.1016/j.contraception.2008.07.017 · Cited by 128 · see citing works
Myths and Misconceptions About Long-Acting Reversible Contraception (LARC)
Russo, J. A., Miller, E. P., & Gold, M. A. (2013) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2013.02.003 · Cited by 123 · see citing works
Bone health in estrogen-free contraception
Hadji, P., Colli, E., & Regidor, P. (2019) · Osteoporosis International · doi:10.1007/s00198-019-05103-6 · Cited by 111 · see citing works
Long-Acting Reversible Contraceptives
Espey, E. L., & Ogburn, T. (2011) · Obstetrics and Gynecology · doi:10.1097/aog.0b013e31820ce2f0 · Cited by 109 · see citing works
Barra, F., Scala, C., & Ferrero, S. (2018) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2018.1461840 · Cited by 100 · see citing works
Tolerability and clinical safety of Implanon®
Blumenthal, P. D., Gemzell‐Danielsson, K., & Marintcheva-Petrova, M. (2008) · The European Journal of Contraception & Reproductive Health Care · doi:10.1080/13625180801960012 · Cited by 108 · see citing works
Hormonal contraception and bone metabolism: a systematic review
Nappi, C., Bifulco, G., Tommaselli, G. A., Gargano, V., & Carlo, C. D. (2012) · Contraception · doi:10.1016/j.contraception.2012.04.009 · Cited by 107 · see citing works
Nexplanon: the new implant for long-term contraception. A comprehensive descriptive review
Palomba, S., Falbo, A. I., Cello, A. D., Materazzo, C., & Zullo, F. (2012) · Gynecological Endocrinology · doi:10.3109/09513590.2011.652247 · Cited by 72 · see citing works
Hohmann, H. L., & Creinin, M. D. (2007) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0b013e318159c2f6 · Cited by 71 · see citing works
Update on hormonal contraception and bone density
Isley, M. M., & Kaunitz, A. M. (2011) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-011-9180-6 · Cited by 67 · see citing works
Bahamondes, L., Monteiro-Dantas, C., Espejo-Arce, X., dos Santos Fernandes, A. M., Lui-Filho, J. F., Perrotti, M., & Petta, C. A. (2006) · Human Reproduction · doi:10.1093/humrep/dei358 · Cited by 66 · see citing works
Oral and depot progestin therapy for endometriosis: towards a personalized medicine
Buggio, L., Somigliana, E., Barbara, G., Frattaruolo, M. P., & Vercellini, P. (2017) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2017.1381086 · Cited by 58 · see citing works
Modesto, W., Dal’Ava, N., MONTEIRO, I. M. U., & Bahamondes, L. G. (2015) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-015-3784-0 · Cited by 55 · see citing works
Contraceptive implants: current perspectives
Rowlands, S., & Searle, S. (2014) · Open Access Journal of Contraception · doi:10.2147/oajc.s55968 · Cited by 54 · see citing works
Overview of the relationship between use of progestogen-only contraceptives and bone mineral density
Banks, E., de González, A. B., & Casabonne, D. (2001) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2001.00296.x · Cited by 54 · see citing works
Bones and Birth Control in Adolescent Girls
Golden, N. H. (2020) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2020.01.003 · Cited by 52 · see citing works
Helping Women Choose Appropriate Hormonal Contraception: Update on Risks, Benefits, and Indications
Spencer, A. L., Bonnema, R. A., & McNamara, M. (2009) · The American Journal of Medicine · doi:10.1016/j.amjmed.2009.01.016 · Cited by 46 · see citing works
The combined contraceptive vaginal ring and bone mineral density in healthy pre-menopausal women
Massai, R., Mäkäräinen, L., Kuukankorpi, A., Klipping, C., Duijkers, I. J. M., & Dieben, T. O. M. (2005) · Human Reproduction · doi:10.1093/humrep/dei117 · Cited by 43 · see citing works
Self-citationBlumenthal, P. D., & Edelman, A. B. (2008) · Obstetrics and Gynecology · doi:10.1097/aog.0b013e31818425b7 · Cited by 41 · see citing works
Margatho, D., Carvalho, N. M., & Bahamondes, L. G. (2020) · The European Journal of Contraception & Reproductive Health Care · doi:10.1080/13625187.2020.1725461 · Cited by 41 · see citing works
Long-acting contraceptives in adolescents
Tolaymat, L. L., & Kaunitz, A. M. (2007) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0b013e3282ef1cd2 · Cited by 40 · see citing works
Novel drug delivery methods for improving efficacy of endometriosis treatments
Garzon, S., Laganà, A. S., Barra, F., Casarin, J., Cromi, A., Raffaelli, R., Uccella, S., Franchi, M. P., Ghezzi, F., & Ferrero, S. (2020) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2021.1829589 · Cited by 42 · see citing works
Monteiro-Dantas, C., Espejo‐Arce, X., Lui-Filho, J. F., Fernandes, A. M. D. S., MONTEIRO, I. M. U., & Bahamondes, L. G. (2007) · Reproductive Health · doi:10.1186/1742-4755-4-11 · Cited by 38 · see citing works
Thacker, H. L. (2011) · Journal of Women s Health · doi:10.1089/jwh.2010.2403 · Cited by 35 · see citing works
Implanon: A Review of the Literature With Recommendations for Clinical Management
Adams, K., & Beal, M. W. (2009) · Journal of Midwifery & Women s Health · doi:10.1016/j.jmwh.2008.09.004 · Cited by 35 · see citing works
Sørdal, T., Grob, P. R., & Verhoeven, C. (2012) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/j.1600-0412.2012.01498.x · Cited by 34 · see citing works
Evidence based contraceptive choices
Scott, A., & Glasier, A. (2006) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2006.03.002 · Cited by 33 · see citing works
Pongsatha, S., Ekmahachai, M., Suntornlimsiri, N., Morakote, N., & Chaovisitsaree, S. (2010) · International Journal of Gynecology & Obstetrics · doi:10.1016/j.ijgo.2010.01.018 · Cited by 31 · see citing works
Contraceptive Care for Adolescents
Whitaker, A. K., & Gilliam, M. L. (2008) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0b013e31816d713e · Cited by 31 · see citing works
Reviewing the role of progesterone therapy in endometriosis
Karim, A., Shafiee, M. N., Aziz, N. H. A., Omar, M. H., Ghani, N. A. A., Lim, P. S., Zin, R. R. M., & Mokhtar, N. M. (2018) · Gynecological Endocrinology · doi:10.1080/09513590.2018.1490404 · Cited by 30 · see citing works
Canadian Contraception Consensus (Part 3 of 4): Chapter 8 – Progestin-Only Contraception
Black, A., Guilbert, É., Costescu, D., Dunn, S., Fisher, W. A., Kives, S. L., Mirosh, M., Norman, W. V., Pymar, H. C., Reid, R. L., et al. (2016) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/j.jogc.2015.12.003 · Cited by 32 · see citing works
Implanon: A New Contraceptive Implant
Fischer, M. A. (2008) · Journal of Obstetric, Gynecologic & Neonatal Nursing · doi:10.1111/j.1552-6909.2008.00247.x · Cited by 29 · see citing works
Adolescent Contraception: Review and Guidance for Pediatric Clinicians
Hartman, L. B., Monasterio, E., & Hwang, L. Y. (2012) · Current problems in pediatric and adolescent health care · doi:10.1016/j.cppeds.2012.05.001 · Cited by 28 · see citing works
Best Practices for Counseling Adolescents about the Etonogestrel Implant
Berlan, E. D., Richards, M. J., Vieira, C. S., Creinin, M. D., Kaunitz, A. M., Fraser, I. S., Edelman, A. B., & Mansour, D. (2020) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2020.06.022 · Cited by 27 · see citing works
Impact of combined and progestogen-only contraceptives on bone mineral density
Sarfati, J., & de Vernejoul, M. C. (2009) · Joint Bone Spine · doi:10.1016/j.jbspin.2008.09.014 · Cited by 27 · see citing works
Safety of implantable contraceptives for women: data from observational studies
Curtis, K. M. (2002) · Contraception · doi:10.1016/s0010-7824(01)00291-8 · Cited by 27 · see citing works
Risk-benefit effects of implantable contraceptives in women
Brache, V., Faúndes, A., & Alvarez, F. (2003) · Expert Opinion on Drug Safety · doi:10.1517/14740338.2.3.321 · Cited by 26 · see citing works
The sexual health of adolescents with cystic fibrosis.
Roberts, S. A., & Green, P. (2005) · PubMed Central · Cited by 26 · see citing works
Considerations for the use of progestin‐only contraceptives
Freeman, S. B., & SHULMAN, L. P. (2010) · Journal of the American Academy of Nurse Practitioners · doi:10.1111/j.1745-7599.2009.00473.x · Cited by 24 · see citing works
Non – contraceptive benefits and risks of contraception
Haider, Z., & D'Souza, R. E. (2009) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2008.12.003 · Cited by 24 · see citing works
Hormonal contraceptive regimens in the perimenopause
Hardman, S. M., & Gebbie, A. E. (2009) · Maturitas · doi:10.1016/j.maturitas.2009.05.001 · Cited by 23 · see citing works
Menstrual Suppression in the Adolescent
Kantartzis, K. L., & Sucato, G. S. (2013) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2012.08.007 · Cited by 23 · see citing works
Common gynecological challenges in adolescents with sickle cell disease
Stimpson, S.-J., Rebele, E. C., & DeBaun, M. R. (2015) · Expert Review of Hematology · doi:10.1586/17474086.2016.1126177 · Cited by 21 · see citing works
Factors associated with bone mineral density in healthy African women
for the MTN-003B Protocol Team, Mgodi, N. M., Kelly, C., Gati, B. M., Greenspan, S. L., Dai, J. Y., Bragg, V., Livant, E., Piper, J. M., Nakabiito, C., et al. (2015) · Archives of Osteoporosis · doi:10.1007/s11657-015-0206-7 · Cited by 21 · see citing works
Gaffield, M. E., Curtis, K. M., Mohllajee, A. P., & Peterson, H. B. (2005) · Contraception · doi:10.1016/j.contraception.2005.08.002 · Cited by 20 · see citing works
FFPRHC Guidance (October 2004) Contraceptive choices for young people
(2004) · Journal of Family Planning and Reproductive Health Care · doi:10.1783/0000000042177018 · Cited by 19 · see citing works
Mise au point sur la contraception progestative
Madélénat, P., & Koskas, M. (2008) · Journal de gynécologie, obstétrique et biologie de la reproduction. Supplément/Journal de gynécologie obstétrique et biologie de la reproduction · doi:10.1016/j.jgyn.2008.06.013 · Cited by 18 · see citing works
Bone health and hormonal contraception
Rocca, M. L., Palumbo, A., BITONTI, G., BRISINDA, C., & Carlo, C. D. (2021) · Minerva Obstetrics and Gynecology · doi:10.23736/s2724-606x.20.04688-2 · Cited by 18 · see citing works
Hohmann, H. L. (2009) · Patient Preference and Adherence · doi:10.2147/ppa.s4299 · Cited by 17 · see citing works
Women in space: A review of known physiological adaptations and health perspectives
Hughes-Fulford, M., Carroll, D. J., Allaway, H., Dunbar, B., & Sawyer, A. (2024) · Experimental Physiology · doi:10.1113/ep091527 · Cited by 16 · see citing works
Martin, D., & Elliott-Sale, K. J. (2016) · Revista Brasileira de Educação Física e Esporte · doi:10.1590/1807-55092016000401087 · Cited by 16 · see citing works
Brown, A. E. (2010) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2010.04.005 · Cited by 16 · see citing works
Contraception for the older woman: an update
Bhathena, R. K., & Guillebaud, J. (2006) · Climacteric · doi:10.1080/13697130600857904 · Cited by 16 · see citing works
Contraceptive methods in adolescence: a narrative review of guidelines
Margaritis, K., Margioula‐Siarkou, G., Margioula‐Siarkou, C., Petousis, S., & Galli‐Τsinopoulou, A. (2023) · The European Journal of Contraception & Reproductive Health Care · doi:10.1080/13625187.2022.2162336 · Cited by 14 · see citing works
Contraceptive Implants: An Overview and Update
Isley, M. M., & Edelman, A. B. (2007) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/j.ogc.2007.01.002 · Cited by 14 · see citing works
Use of hormonal contraception in adolescents: skeletal health issues
Tolaymat, L. L., & Kaunitz, A. M. (2009) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0b013e32832c9cc6 · Cited by 14 · see citing works
Implanon: The Subdermal Contraceptive Implant
Isley, M. M. (2010) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2010.03.006 · Cited by 13 · see citing works
Use of the etonogestrel-releasing contraceptive implant
Grentzer, J. M., McNicholas, C. P., & Peipert, J. F. (2013) · Expert Review of Obstetrics & Gynecology · doi:10.1586/17474108.2013.811941 · Cited by 12 · see citing works
Rafie, S., McIntosh, J. E., Shealy, K. M., Borgelt, L. M., Forinash, A. B., Shrader, S. P., Koepf, E. R., McClendon, K. S., Griffin, B. L., Horlen, C. K., et al. (2014) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1002/phar.1457 · Cited by 11 · see citing works
Merki‐Feld, G. S., & Bitzer, J. (2020) · The European Journal of Contraception & Reproductive Health Care · doi:10.1080/13625187.2020.1743826 · Cited by 11 · see citing works
Contraception for HIV-Infected Adolescents
Kourtis, A. P., & Mirza, A. (2016) · PEDIATRICS · doi:10.1542/peds.2016-1892 · Cited by 11 · see citing works
FSRH Guideline (February 2021) Progestogen-only Implant
(2021) · BMJ Sexual & Reproductive Health · doi:10.1136/bmjsrh-2021-chc · Cited by 10 · see citing works
Contraception for adolescents with lupus
Tesher, M. S., Whitaker, A. K., Gilliam, M. L., Wagner‐Weiner, L., & Onel, K. B. (2010) · Pediatric Rheumatology · doi:10.1186/1546-0096-8-10 · Cited by 10 · see citing works
Etonogestrel implant effectiveness
Dugré, N., Choksi, N., & Kirkwood, J. E. M. (2022) · Canadian Family Physician · doi:10.46747/cfp.6808594 · Cited by 9 · see citing works
Impact de la contraception estroprogestative et progestative sur la densité minérale osseuse
Trémollières, F. (2005) · Gynécologie Obstétrique & Fertilité · doi:10.1016/j.gyobfe.2005.05.016 · Cited by 9 · see citing works
Contraception - Update and Trends
Rabe, T. (2007) · Journal für Kardiologie (Krause & Pachernegg GmbH) · Cited by 8 · see citing works
Bone mineral density in postmenopausal women with and without breast cancer
Conde, D. M., Costa‐Paiva, L., Martínez, E. Z., & Pinto-Neto, A. M. (2012) · Revista da Associação Médica Brasileira · doi:10.1590/s0104-42302012000600011 · Cited by 6 · see citing works
Duvan, C. İ., Onaran, Y., Keskin, E. A., Yüce, E., Yanık, B., Kafalı, H. C., & Turhan, N. Ö. (2016) · Journal of Family Planning and Reproductive Health Care · doi:10.1136/jfprhc-2015-101375 · Cited by 6 · see citing works
Hormonal contraception and medical readiness for female service members
Ricker, E. A., Koltun, K. J., & de la Motte, S. J. (2024) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2024.05.044 · Cited by 5 · see citing works
Lahoti, A., Yu, C., Brar, P. C., Dalgo, A., Gourgari, E., Harris, R. M., Kamboj, M. K., Marks, S. D., Nandagopal, R., PAGE, L. C., et al. (2021) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem-2020-0539 · Cited by 5 · see citing works
Contraceptive Devices for Women: Implants, Intrauterine Devices and Other Products
Craik, J., & Rowlands, S. (2014) · Springer eBooks · doi:10.1007/978-3-319-12406-3_8 · Cited by 5 · see citing works
(2001) · Drug and Therapeutics Bulletin · doi:10.1136/dtb.2001.39857 · Cited by 5 · see citing works
Grandi, G., Feliciello, L., Sgandurra, A., Pedrini, V., Guariglia, G., Ferrari, V., Duca, N. D., & Marca, A. L. (2024) · The European Journal of Contraception & Reproductive Health Care · doi:10.1080/13625187.2024.2434846 · Cited by 4 · see citing works
Consensus conference results on contraception in women beyond 40 years of age
Cagnacci, A., Fruzzetti, F., Bruni, V., Gambera, A., Guida, M., Bonaccorsi, G., Londero, A. P., & for the Italian Society of Contraception (S.I.C.) (2025) · The European Journal of Contraception & Reproductive Health Care · doi:10.1080/13625187.2025.2544754 · Cited by 4 · see citing works
Hormonal Contraception and Bone Health
Isley, M. M. (2012) · Journal watch · doi:10.1056/wh201202160000001 · Cited by 4 · see citing works
Mise au point sur la contraception progestative
Madélénat, P., & Koskas, M. (2009) · Sages-Femmes · doi:10.1016/j.sagf.2008.06.001 · Cited by 4 · see citing works
Black, A., Guilbert, É., Costescu, D., Dunn, S., Fisher, W. A., Kives, S. L., Mirosh, M., Norman, W. V., Pymar, H. C., Reid, R. L., et al. (2016) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/j.jogc.2016.03.005 · Cited by 4 · see citing works
Pharmacological female contraception: an overview of past and future use
Economidis, M. A., & Mishell, D. R. (2005) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.14.4.449 · Cited by 4 · see citing works
Hormonal contraception and bone mineral density
Beksinska, M. E., & Smit, J. A. (2011) · Expert Review of Obstetrics & Gynecology · doi:10.1586/eog.11.19 · Cited by 4 · see citing works
Rationaliser la contraception progestative pure (hors DIU au lévonorgestrel)
Jamin, C., & Madélénat, P. (2008) · Gynécologie Obstétrique & Fertilité · doi:10.1016/j.gyobfe.2008.01.015 · Cited by 3 · see citing works
Hormonal and Non-Hormonal Management of Vasomotor Symptoms: A Narrated Review
Tan, O., Pinto, A., & Carr, B. R. (2013) · Cited by 3 · see citing works
Complications of Long-Acting Reversible Contraceptive Modalities
Irgens-Moller, N., & Baum, C. R. (2023) · Pediatric Emergency Care · doi:10.1097/pec.0000000000002970 · Cited by 2 · see citing works
Kontrazeption und Familienplanung
Amari, F., Beyer, D. A., Ludwig, M., Felberbaum, R. E., Weiss, J. M., & Diedrich, K. (2012) · Springer eBooks · doi:10.1007/978-3-642-20923-9_13 · Cited by 2 · see citing works
Progestin-Only Contraception and Bone Health
Isley, M. M. (2017) · Current Obstetrics and Gynecology Reports · doi:10.1007/s13669-017-0201-7 · Cited by 2 · see citing works
Bone mineral density in postmenopausal women with and without breast cancer
Conde, D. M., Costa‐Paiva, L., Martínez, E. Z., & Pinto-Neto, A. M. (2012) · Revista da Associação Médica Brasileira · doi:10.1016/s0104-4230(12)70270-1 · Cited by 2 · see citing works
Feisullin, K., & Westhoff, C. L. (2010) · Principles of Gender-Specific Medicine · doi:10.1016/b978-0-12-374271-1.00033-2 · Cited by 2 · see citing works
Bone Health and Hormonal Contraception
Dragoman, M. V., Kaunitz, A. M., & McClung, M. R. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1233-9_16 · Cited by 2 · see citing works
Does the use of hormonal contraceptives affect bone mineral density?
Bahamondes, L. G. (2007) · Expert Review of Obstetrics & Gynecology · doi:10.1586/17474108.2.2.141 · Cited by 2 · see citing works
Hormonal contraception in perimenopausal women
Whitburn, S., McNamee, K. M., Boerma, C. J., & Bateson, D. J. (2025) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2025.102655 · Cited by 1 · see citing works
Siconolfi, A., Azzi, M., Lami, A., Sanna, E., Seracchioli, R., & Meriggiola, M. C. (2025) · Contraception and Reproductive Medicine · doi:10.1186/s40834-025-00399-8 · Cited by 1 · see citing works
Impact de la contraception estroprogestative et progestative sur la densité minérale osseuse
Sarfati, J., & de Vernejoul, M. C. (2009) · Revue du Rhumatisme · doi:10.1016/j.rhum.2008.09.013 · Cited by 1 · see citing works
Implanon™: A New Implantable Contraceptive
Newberry, Y. G. (2007) · Nursing for Women s Health · doi:10.1111/j.1751-486x.2007.00252.x · Cited by 1 · see citing works
Ahrendt, H.-J., Goeckenjan, M., & Rabe, T. (2011) · Der Gynäkologe · doi:10.1007/s00129-011-2863-y · Cited by 1 · see citing works
- Authors
- Beerthuizen, R., van Beek, A., Massai, R., Mäkäräinen, L., Hout, J. I., & Bennink, H. C.
- Affiliations
- Streekziekenhuis Koningin Beatrix (NL)
- Venue
- Human Reproduction
- Publisher
- Oxford University Press (OUP)
- Published
- 2000-01
- Volume
- 15
- Issue
- 1
- Pages
- 118-122
- ISSN
- 0268-1161 (ISSN-L)
- 1460-2350
- OpenAlex
- W2101744447
- Cited by
- 127
- References
- 13
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 4 · 2023: 3 · 2022: 3 · 2021: 5 · 2020: 5 · 2019: 2 · 2018: 4 · 2017: 4 · 2016: 6 · 2015: 5 · 2014: 7 · 2013: 7 · 2012: 10
- FWCI
- 1.58
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Human Reproduction (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Health and Contraception
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Keywords
- bone mineral density, Implanon, etonogestrel, contraceptive implants, progestogens, intrauterine devices, non-hormonal contraception, osteoporosis risk, estradiol, young women, peak bone mass
- MeSH terms
- Adolescent, Adult, Body Weight, Contraceptive Agents, Female, Drug Implants, Estradiol, Female, Femur, Humans, Intrauterine Devices, Prospective Studies, Radius, Vinyl Compounds, Absorptiometry, Photon, Bone Density, Desogestrel, Progesterone Congeners
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
