The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
In search of candidate genes critically expressed in the human endometrium during the window of implantation
Abstract
BACKGROUND: In this prospective randomized blinded clinical trial, we examined gene expression profiles of the human endometrium during the early and mid-luteal phases of the natural cycle. METHODS: An endometrial biopsy was performed on day 16 (LH +3) or on day 21 (LH +8), followed by RNA extraction and microarray analysis using an Affymetrix HG-U95A microchip. Data analysis was carried out using pairwise multiple group comparison with the significance analysis of microarrays (SAM) software. RESULTS: With a false discovery rate of 0, the analysis revealed that 107 genes were significantly and differently expressed (> or =2-fold) during the early versus the mid-luteal phase of the cycle. Forty-five of these genes have not been previously linked to endometrial receptivity. Validation of the microarray data was accomplished using semiquantitative RT-PCR. We demonstrated the presence of estrogen and progesterone response elements (ERE and PRE) by analysis of the 5'-flanking regions of a subset of differentially regulated genes. CONCLUSIONS: Using a strict bioinformatics approach of microarray data, we demonstrated significant changes in candidate genes during the transition of the early to the mid-luteal phase of the human endometrium that may have functional significance for the opening and maintenance of the window of implantation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Elements of Statistical Learning
Hastie, T., Friedman, J., & Tibshirani, R. (2001) · Springer Series in Statistics · doi:10.1007/978-0-387-21606-5 · Cited by 24,162
Cluster analysis and display of genome-wide expression patterns
Eisen, M. B., Spellman, P. T., Brown, P. O., & Botstein, D. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.25.14863 · Cited by 16,184
In silico prediction of protein-protein interactions in human macrophages
Souiai, O., Guerfali, F., Ben Miled, S., Brun, C., & Benkahla, A. (2014) · BMC Research Notes · doi:10.1186/1756-0500-7-157 · Cited by 10,803
Significance analysis of microarrays applied to the ionizing radiation response
Tusher, V. G., Tibshirani, R., & Chu, G. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.091062498 · Cited by 10,568
Noyes, R. W., Hertig, A. T., & Rock, J. (1950) · Fertility and Sterility · doi:10.1016/s0015-0282(16)30062-0 · Cited by 2,843
Amplified RNA synthesized from limited quantities of heterogeneous cDNA.
Van Gelder, R. N., von Zastrow, M. E., Yool, A., Dement, W. C., Barchas, J. D., & Eberwine, J. H. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.5.1663 · Cited by 1,262
Time of Implantation of the Conceptus and Loss of Pregnancy
Wilcox, A. J., Baird, D. D., & Weinberg, C. R. (1999) · New England Journal of Medicine · doi:10.1056/nejm199906103402304 · Cited by 1,081
Estrogen receptor interaction with estrogen response elements
Klinge, C. M. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.14.2905 · Cited by 1,081
Roberts, C. J., Nelson, B., Marton, M. J., Stoughton, R., Meyer, M. R., Bennett, H. A., He, Y. D., Dai, H., Walker, W. L., Hughes, T. R., et al. (2000) · Science · doi:10.1126/science.287.5454.873 · Cited by 855
Global gene profiling in human endometrium during the window of implantation
Kao, L. C., Tulac, S., Lobo, S., Imani, B., Yang, J. P., Germeyer, A., Osteen, K., Taylor, R. N., Lessey, B. A., & Giudice, L. C. (2002) · Endocrinology · doi:10.1210/endo.143.6.8885 · Cited by 727
Cited by
Roadmap to embryo implantation: clues from mouse models
Wang, H., & Dey, S. K. (2006) · Nature Reviews Genetics · doi:10.1038/nrg1808 · Cited by 1,298
A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature
Díaz-Gimeno, P., Horcajadas, J. A., Martínez-Conejero, J. A., Esteban, F. J., Alamá, P., Pellicer, A., & Simón, C. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.04.063 · Cited by 687
Talbi, S., Hamilton, A. E., Vo, K. C., Tulac, S., Overgaard, M. T., Dosiou, C., Le Shay, N., Nezhat, C. N., Kempson, R., Lessey, B. A., et al. (2006) · Endocrinology · doi:10.1210/en.2005-1076 · Cited by 589
Physiological and molecular determinants of embryo implantation
Zhang, S., Lin, H., Kong, S., Wang, S., Wang, H., Wang, H., & Armant, D. R. (2013) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2012.12.011 · Cited by 587
Altmäe, S., Koel, M., Võsa, U., Adler, P., Suhorutšenko, M., Laisk-Podar, T., Kukushkina, V., Saare, M., Velthut-Meikas, A., Krjutškov, K., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-10098-3 · Cited by 265
Metadata
- Authors
- Mirkin, S., Arslan, M., Churikov, D., Corica, A., Diaz, J. I., Williams, S., Bocca, S., & Oehninger, S.
- Venue
- Human Reproduction
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-05-05
- Volume
- 20
- Issue
- 8
- Pages
- 2104-2117
- ISSN
- 0268-1161 (ISSN-L)
- 1460-2350
- OpenAlex
- W2153290165
- Cited by
- 264
- References
- 45
- FWCI
- 5.26
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: In search of candidate genes critically expressed in the human endometrium during the window of implantation. https://app.cochat.ai/papers/10.1093/humrep/dei051
- The paper
- Mirkin, S., Arslan, M., Churikov, D., Corica, A., Diaz, J. I., Williams, S., Bocca, S., & Oehninger, S. (2005). In search of candidate genes critically expressed in the human endometrium during the window of implantation. Human Reproduction. https://doi.org/10.1093/humrep/dei051
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
