Management of ovarian endometriomas
Abstract
The efficiency of medical therapy as a unique treatment for endometrioma has not been demonstrated. Operative laparoscopic management is the 'gold standard' for surgical treatment, and there are no indications to prescribe medical treatment before cystectomy. Post-operative administration of low-dose cyclic oral contraceptives does not significantly affect the long-term recurrence of endometriosis after surgical treatment. In case of infertility, the management of endometriomas is controversial. Recurrent ovarian surgery is not recommended.
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Endometrioma management is difficult because their link to pain is uncertain.
“Treating endometriomas is not straightforward as their association with pain is unclear (Chapron et al., 2002;Vercellini et al., 2009b).”
From Chronic pelvic pain and endometriosis: translational evidence of the relationship and implications (2011) · cites this paper as Chapron et al., 2002
The Introduction (p. 1) describes problems managing endometriomas. The section on medical treatment (p. 4) notes that postoperative studies did not distinguish endometriomas from other lesions when assessing pain, but it does not state that the association between endometriomas and pain is unclear or identify that uncertainty as the reason treatment is difficult. (LLM, conf=0.80)
Experimental — accuracy not yet measuredA cyst recurrence rate of approximately 10% per year has been reported after surgery for ovarian endometriomas.
“A cyst recurrence rate of ~10% per year has been reported after surgery for ovarian endometriomas (Chapron et al., 2002; Koga et al., 2006; Liu et al., 2007; Guo, 2009; Koga et al., 2015).”
From When more is not better: 10 ‘don’ts’ in endometriosis management. An ETIC* position statement (2019) · cites this paper as Chapron et al., 2002
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Cites
Chapron, C., Querleu, D., Bruhat, M. A., Madelenat, P., Fernandez, H., Pierre, F., & Dubuisson, J. B. (1998) · Human Reproduction · doi:10.1093/humrep/13.4.867 · Cited by 406 · see citing works
Self-citationDonnez, J., Nisolle, M., Gillet, N., Smets, M., Bassil, S., & Casanas-Roux, F. (1996) · Human Reproduction · doi:10.1093/humrep/11.3.641 · Cited by 360 · see citing works
<b>Ovarian atypical endometriosis: its close association with malignant epithelial tumours</b>
FUKUNAGA, M., NOMURA, K., ISHIKAWA, E., & USHIGOME, S. (1997) · Histopathology · doi:10.1046/j.1365-2559.1997.d01-592.x · Cited by 333 · see citing works
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Research works printed but not linked: 3
- Chapron, C., Fauconnier, A., Vieira, M., Barakat, H., Dousset, B., Pansini, V., Vacher-Lavenu, M.C. and Dubuisson, J.B. (2002b) Deeply infiltrating endometriosis: surgical implications of the anatomic distribution. Hum. Reprod. (in press).
- Jones, K.D. and Sutton, C.J.G. (2000) Laparoscopic management of ovarian endometriomas: a critical review of current practice. Curr. Opin. Obstet. Gynecol. , 12 , 309-315.
- Saidi, M.H., Vancaillie, T.G., White, A.J., Sadler, R.K., Akright, B.D. and Farhart, S.A. (1996b) Complications of major operative laparoscopy. A review of 452 cases. J. Reprod. Med. , 41 , 471-476.
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ESHRE guideline for the diagnosis and treatment of endometriosis
Kennedy, S., Bergqvist, A., Chapron, C., D’Hooghe, T., Dunselman, G., Greb, R., Hummelshoj, L., Prentice, A., & Saridogan, E. (2005) · Human Reproduction · doi:10.1093/humrep/dei135 · Cited by 1,584 · see citing works
Self-citationChronic pelvic pain and endometriosis: translational evidence of the relationship and implications
Stratton, P., & Berkley, K. J. (2011) · Human Reproduction Update · doi:10.1093/humupd/dmq050 · Cited by 442 · see citing works
<i>Endometriosis and Infertility</i>: <i>Epidemiology and Evidence‐based Treatments</i>
Ozkan, S., Murk, W., & Arici, A. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1434.007 · Cited by 347 · see citing works
The effect of surgery for symptomatic endometriosis: the other side of the story
Vercellini, P., Crosignani, P. G., Abbiati, A., Somigliana, E., Viganò, P., & Fedele, L. (2009) · Human Reproduction Update · doi:10.1093/humupd/dmn062 · Cited by 339 · see citing works
Surgery for endometriosis-associated infertility: a pragmatic approach
Vercellini, P., Somigliana, E., Vigano, P., Abbiati, A., Barbara, G., & Crosignani, P. G. (2009) · Human Reproduction · doi:10.1093/humrep/den379 · Cited by 269 · see citing works
Seracchioli, R., Mabrouk, M., Manuzzi, L., Vicenzi, C., Frasca, C., Elmakky, A., & Venturoli, S. (2009) · Human Reproduction · doi:10.1093/humrep/dep259 · Cited by 158 · see citing works
Seracchioli, R., Mabrouk, M., Frascà, C., Manuzzi, L., Savelli, L., & Venturoli, S. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2009.03.083 · Cited by 158 · see citing works
Muzii, L., Di Tucci, C., Achilli, C., Di Donato, V., Musella, A., Palaia, I., & Panici, P. B. (2016) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.08.074 · Cited by 142 · see citing works
Recurrence rate of endometriomas following a laparoscopic cystectomy
Kikuchi, I., Takeuchi, H., Kitade, M., Shimanuki, H., Kumakiri, J., & Kinoshita, K. (2006) · Acta Obstetricia et Gynecologica Scandinavica · doi:10.1080/00016340600627154 · Cited by 116 · see citing works
Endometriosis-associated infertility: surgery and IVF, a comprehensive therapeutic approach
Barri, P. N., Coroleu, B., Tur, R., Barri-Soldevila, P. N., & Rodríguez, I. (2010) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2010.04.026 · Cited by 117 · see citing works
Continuous versus cyclic oral contraceptives for the treatment of endometriosis: a systematic review
Zorbas, K. A., Economopoulos, K. P., & Vlahos, N. F. (2015) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-015-3641-1 · Cited by 114 · see citing works
EVANS, M. B., & DECHERNEY, A. H. (2017) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0000000000000295 · Cited by 108 · see citing works
Takamura, M., Koga, K., Osuga, Y., Takemura, Y., Hamasaki, K., Hirota, Y., Yoshino, O., & Taketani, Y. (2009) · Human Reproduction · doi:10.1093/humrep/dep297 · Cited by 98 · see citing works
Jee, B. C., Lee, J. Y., Suh, C. S., Kim, S. H., Choi, Y. M., & Moon, S. Y. (2009) · Fertility and Sterility · doi:10.1016/j.fertnstert.2007.11.027 · Cited by 79 · see citing works
Alborzi, S., Zahiri Sorouri, Z., Askari, E., Poordast, T., & Chamanara, K. (2019) · Reproductive Medicine and Biology · doi:10.1002/rmb2.12286 · Cited by 65 · see citing works
When more is not better: 10 ‘don’ts’ in endometriosis management. An ETIC* position statement
Club, E. E. T. I., Alio, L., Angioni, S., Arena, S., Bartiromo, L., Bergamini, V, Berlanda, N., Bonin, C., Busacca, M., Candiani, M., et al. (2019) · Human Reproduction Open · doi:10.1093/hropen/hoz009 · Cited by 64 · see citing works
New trends for the medical treatment of endometriosis
Rocha, A. L. L., Reis, F. M., & Petraglia, F. (2012) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.2012.683783 · Cited by 60 · see citing works
Muzii, L., Galati, G., Di Tucci, C., Di Feliciantonio, M., Perniola, G., Di Donato, V., Benedetti Panici, P., & Vignali, M. (2020) · Gynecological Endocrinology · doi:10.1080/09513590.2019.1640199 · Cited by 55 · see citing works
Miquel, L., Preaubert, L., Gnisci, A., Resseguier, N., Pivano, A., Perrin, J., & Courbiere, B. (2020) · PLOS ONE · doi:10.1371/journal.pone.0239846 · Cited by 45 · see citing works
“Endometriomas are detected in up to 44% of women with endometriosis and are associated with pelvic pain, deep lesions and disease severity [4].”
BackgroundCho, S., Jung, J. A., Lee, Y., Kim, H. Y., Seo, S. K., Choi, Y. S., Lee, J. S., & Lee, B. S. (2014) · Acta Obstetricia et Gynecologica Scandinavica · doi:10.1111/aogs.12294 · Cited by 39 · see citing works
The age-related recurrence of endometrioma after conservative surgery
Seo, J.-W., Lee, D.-Y., Yoon, B.-K., & Choi, D. (2017) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2016.11.015 · Cited by 32 · see citing works
New drugs in development for the treatment of endometriosis
Fedele, L., Somigliana, E., Frontino, G., Benaglia, L., & Vigano, P. (2008) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.17.8.1187 · Cited by 30 · see citing works
Long, Q., Zheng, H., Liu, X., & Guo, S.-W. (2019) · Reproductive Sciences · doi:10.1177/1933719119828066 · Cited by 16 · see citing works
An endometriotic vault fistula presenting with monthly bleeding after hysterectomy
Aydin, Y., Atis, A., Ercan, E., & Donmez, M. (2009) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-009-1020-5 · Cited by 5 · see citing works
- Authors
- Chapron, C.
- Affiliations
- Hôpital Cochin (FR)
- Corresponding author
- Chapron, C.
- ORCID
- Chapron, C.
- Venue
- Human Reproduction Update
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-11-01
- Volume
- 8
- Issue
- 6
- Pages
- 591-597
- ISSN
- 1355-4786 (ISSN-L)
- 1460-2369
- OpenAlex
- W2123779105
- Cited by
- 244
- References
- 3
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 12 · 2023: 5 · 2022: 8 · 2021: 13 · 2020: 12 · 2019: 18 · 2018: 11 · 2017: 12 · 2016: 10 · 2015: 16 · 2014: 6 · 2013: 10 · 2012: 12
- FWCI
- 0.72
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Human Reproduction Update (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ectopic Pregnancy Diagnosis and Management
- Keywords
- endometrioma, endometriosis, laparoscopic cystectomy, medical therapy, low-dose oral contraceptives, endometriosis recurrence, infertility
- MeSH terms
- Contraceptives, Oral, Endometriosis, Female, Humans, Infertility, Female, Ovarian Diseases, Laparoscopy, Recurrence, Pelvic Pain, Reproductive Techniques, Assisted
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