Sex Hormones, Insulin Sensitivity, and Diabetes Mellitus
Abstract
Sex differences and the role of gonadal hormones in modulating insulin sensitivity and glucose tolerance are of increasing interest and importance because of the increasing prevalence of type 2 diabetes mellitus and the metabolic abnormalities associated with aging. Body composition is closely associated with insulin sensitivity, and increased body fat, particularly in the visceral compartment, is a risk factor for developing type 2 diabetes mellitus. Sex differences in body composition and/or insulin sensitivity are evident in humans throughout the lifespan. Ovarian hormones influence insulin sensitivity across the menstrual cycle, during pregnancy, and in the menopausal transition. Similarly, estrogens and progestins used for contraception and hormone replacement therapy affect glucoregulation. Nonhuman primates and humans have similar life histories and reproductive characteristics. As a result, nonhuman primates provide a valuable model for investigating factors related to insulin sensitivity. Studies of nonhuman primates have contributed significantly to our understanding of sex differences and the influence of sex steroids in this context. This brief review surveys present knowledge of the sex differences in body composition, insulin sensitivity, and risk for development of type 2 diabetes mellitus derived from studies in humans and nonhuman primates. The influences of endogenous and exogenous gonadal steroids are emphasized.
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Influences of sex hormones on insulin sensitivity have long been suspected.
“However, influences of sex hormones on insulin sensitivity have long been suspected37, and sex-specific effects of gonadal hormones are plausible.”
From Brain insulin action on peripheral insulin sensitivity in women depends on menstrual cycle phase (2023) · cites this paper as [37]
Cites
1 retracted
Changes in energy balance and body composition at menopause: a controlled longitudinal study.
Poehlman, E. T., Toth, M. J., & Gardner, A. W. (1995) · Annals of Internal Medicine · doi:10.7326/0003-4819-123-9-199511010-00005 · Cited by 520 · cited 2× · see citing works
“There is an increase in glucose and insulin levels associated with the menopausal transition (Carr 2003), which may be related to changes in body composition (Poehlman et al. 1995).”
BackgroundRetractedWriting Group for the Women's Health Initiative Investigators (2002) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.288.3.321 · Cited by 15,889 · see citing works
Hulley, S. (1998) · JAMA · doi:10.1001/jama.280.7.605 · Cited by 6,216 · see citing works
Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis
Hales, C. N., & Barker, D. J. P. (1992) · Diabetologia · doi:10.1007/bf00400248 · Cited by 3,294 · see citing works
Valery (1995) · doi:10.1001/jama.1995.03520270033028 · Cited by 2,320 · see citing works
International Journal of Obesity
(2019) · International Journal of Obesity · doi:10.1038/41366.1476-5497 · Cited by 2,092 · see citing works
The Emergence of the Metabolic Syndrome with Menopause
Carr, M. C. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-030242 · Cited by 1,449 · see citing works
Banting lecture 1980: of pregnancy and progeny.
Freinkel, N. (1980) · Diabetes · doi:10.2337/diab.29.12.1023 · Cited by 1,366 · see citing works
Fetal nutrition and adult disease
Godfrey, K. M., & Barker, D. J. P. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.5.1344s · Cited by 1,329 · see citing works
Obesity and Risk of Type 2 Diabetes and Cardiovascular Disease in Children and Adolescents
Goran, M. I., Ball, G. D. C., & Cruz, M. L. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021442 · Cited by 734 · see citing works
Longitudinal Study on Pubertal Insulin Resistance
Goran, M. I., & Gower, B. A. (2001) · Diabetes · doi:10.2337/diabetes.50.11.2444 · Cited by 713 · see citing works
McCance, D. R., Pettitt, D. J., Hanson, R. L., Jacobsson, L., Knowler, W. C., & Bennett, P. H. (1994) · BMJ · doi:10.1136/bmj.308.6934.942 · Cited by 693 · see citing works
Kanaya, A. M., Herrington, D., Vittinghoff, E., Lin, F., Grady, D., Bittner, V., Cauley, J. A., & Barrett-Connor, E. (2003) · Annals of Internal Medicine · doi:10.7326/0003-4819-138-1-200301070-00005 · Cited by 633 · see citing works
Oh, J.-Y., Barrett-Connor, E., Wedick, N. M., & Wingard, D. L. (2002) · Diabetes Care · doi:10.2337/diacare.25.1.55 · Cited by 594 · see citing works
Sex differences in the relation of visceral adipose tissue accumulation to total body fatness
Lemieux, S., Prud’homme, D., Bouchard, C., Tremblay, A., & Després, J. (1993) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/58.4.463 · Cited by 561 · see citing works
Hockaday, T. D. R., & Yajnik, C. S. (2003) · Diabetologia · doi:10.1007/s00125-002-1024-1 · Cited by 470 · see citing works
Body Composition during the First 2 Years of Life: An Updated Reference
Butte, N. F., Hopkinson, J. M., Wong, W. W., Smith, E. O., & Ellis, K. J. (2000) · Pediatric Research · doi:10.1203/00006450-200005000-00004 · Cited by 458 · see citing works
Postmenopausal hormone replacement therapy prevents central distribution of body fat after menopause
Haarbo, J., Marslew, U., Gotfredsen, A., & Christiansen, C. (1991) · Metabolism · doi:10.1016/0026-0495(91)90037-w · Cited by 441 · see citing works
Godsland, I. F., Crook, D., Simpson, R., Proudler, T., Felton, C., Lees, B., Anyaoku, V., Devenport, M., & Wynn, V. (1990) · New England Journal of Medicine · doi:10.1056/nejm199011153232003 · Cited by 417 · see citing works
Race, Visceral Adipose Tissue, Plasma Lipids, and Lipoprotein Lipase Activity in Men and Women
Després, J., Couillard, C., Gagnon, J., Bergeron, J., Leon, A. S., Rao, D. C., Skinner, J. S., Wilmore, J. H., & Bouchard, C. (2000) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.20.8.1932 · Cited by 386 · see citing works
Induction of insulin resistance by androgens and estrogens
Polderman, K. H., Gooren, L. J., Asscheman, H., Bakker, A., & Heine, R. J. (1994) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.79.1.8027240 · Cited by 382 · see citing works
Effects of sex steroids on components of the insulin resistance syndrome in transsexual subjects
Elbers, J. M. H., Giltay, E. J., Teerlink, T., Scheffer, P. G., Asscheman, H., Seidell, J. C., & Gooren, L. J. (2003) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2003.01753.x · Cited by 318 · see citing works
Insulin Sensitivity, Insulin Secretion, and Abdominal Fat
Wagenknecht, L. E., Langefeld, C. D., Scherzinger, A. L., Norris, J. M., Haffner, S. M., Saad, M. F., & Bergman, R. N. (2003) · Diabetes · doi:10.2337/diabetes.52.10.2490 · Cited by 302 · see citing works
Hill, J. O., Sidney, S., Lewis, C. E., Tolan, K., Scherzinger, A. L., & Stamm, E. R. (1999) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.3.381 · Cited by 257 · see citing works
Insulin resistance, secretion, and metabolism in users of oral contraceptives
Godsland, I. F., Walton, C., Felton, C. V., Proudler, A. J., Patel, A., & Wynn, V. (1992) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.74.1.1530790 · Cited by 252 · see citing works
Andersson, B., Mattsson, L., Hahn, L., Mårin, P., Lapidus, L., Holm, G., Bengtsson, B., & Björntorp, P. A. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.2.3746 · Cited by 215 · see citing works
Godsland, I. F., GANGAR, K. F., Walton, C., Cust, M. P., Whitehead, M. I., Wynn, V., & Stevenson, J. C. (1993) · Metabolism · doi:10.1016/0026-0495(93)90058-v · Cited by 213 · see citing works
Resko, J. A., Ellinwood, W. E., Pasztor, L. M., & Buhl, A. E. (1980) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-50-5-900 · Cited by 207 · see citing works
HANSEN, B. C., & Bodkin, N. L. (1986) · Diabetologia · doi:10.1007/bf00870281 · Cited by 204 · see citing works
Lindheim, S. R., Presser, S. C., Ditkoff, E. C., Vijod, M. A., Stanczyk, F. Z., & Løbo, R. A. (1993) · Fertility and Sterility · doi:10.1016/s0015-0282(16)56218-9 · Cited by 199 · see citing works
Løbo, R. A., Bush, T. L., Carr, B. R., & Pickar, J. H. (2001) · Fertility and Sterility · doi:10.1016/s0015-0282(01)01829-5 · Cited by 199 · see citing works
Damm, P., Kühl, C., Bertelsen, A., & Mølsted‐Pedersen, L. (1992) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(11)91559-2 · Cited by 194 · see citing works
Chronic Hyperinsulinemia in the Fetal Rhesus Monkey: Effects on Fetal Growth and Composition
Susa, J. B., McCormick, K. L., Widness, J. A., Singer, D. B., Oh, W., Admsons, K., & Schwartz, R. (1979) · Diabetes · doi:10.2337/diab.28.12.1058 · Cited by 187 · see citing works
Ra, L., Pickar, J. H., Ra, W., Walsh, B., & Hirvonen, E. (1994) · PubMed · Cited by 167 · see citing works
Advances in Veterinary Science and Comparative Medicine
Radostits, O. M. (1989) · Advances in veterinary science and comparative medicine · doi:10.1016/b978-0-12-039233-9.50001-9 · Cited by 166 · see citing works
Gestational diabetes: predictors of subsequent disordered glucose metabolism.
Coustan, D. R., Carpenter, M. W., O'Sullivan, P. S., & Carr, S. R. (1993) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(93)90358-p · Cited by 153 · see citing works
Nonhuman Primate Models of Menopause Workshop1
Bellino, F. L., & Wise, P. M. (2003) · Biology of Reproduction · doi:10.1095/biolreprod.102.005215 · Cited by 151 · see citing works
Reubinoff, B. E., Wurtman, J. J., Rojansky, N., Adler, D., Stein, P., Schenker, J. G., & Brzezinsky, A. (1995) · Fertility and Sterility · doi:10.1016/s0015-0282(16)57910-2 · Cited by 148 · see citing works
Intravenous Glucose Tolerance Test-Derived Insulin Sensitivity Changes during the Menstrual Cycle*
Valdés, C. T., & Elkind-Hirsch, K. E. (1991) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-72-3-642 · Cited by 141 · see citing works
Andersson, B. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.82.2.638 · Cited by 139 · see citing works
Li, C., Johnson, M. S., & Goran, M. I. (2001) · Diabetes Care · doi:10.2337/diacare.24.12.2035 · Cited by 138 · see citing works
Simon, D., Charles, M.-A., Lahlou, N., Nahoul, K., Oppert, J.-M., Gouault-Heilmann, M., Lemort, N., Thibult, N., Joubert, E., Balkau, B., et al. (2001) · Diabetes Care · doi:10.2337/diacare.24.12.2149 · Cited by 136 · cited 2× · see citing works
“Although testosterone replacement therapy in hypogonadal men appears to have either a neutral (Tripathy et al. 1998) or a beneficial effect on insulin sensitivity (Simon et al. 2001), numerous studies of hormone replacement therapy (HRT1) in women have yielded variable results.”
BackgroundResultManson, J. E., Rimm, E. B., Colditz, G. A., Willett, W. C., Nathan, D. M., Arky, R. A., Rosner, B., Hennekens, C. H., Speizer, F. E., & Stampfer, M. J. (1992) · Annals of Epidemiology · doi:10.1016/1047-2797(92)90011-e · Cited by 135 · see citing works
Serum leptin concentration, body composition, and gonadal hormones during puberty
Demerath, E. W., Towne, B., Wisemandle, W., Blangero, J., Chumlea, W. C., & Siervogel, M. (1999) · International Journal of Obesity · doi:10.1038/sj.ijo.0800902 · Cited by 121 · see citing works
The effect of age on insulin resistance and secretion: a review.
Muller, D. C., Elahi, D., Tobin, J. D., & Andres, R. (1996) · PubMed · Cited by 114 · see citing works
Hormone Replacement Therapy, Insulin Sensitivity, and Abdominal Obesity in Postmenopausal Women
Ryan, A. S., Nicklas, B. J., & Berman, D. M. (2002) · Diabetes Care · doi:10.2337/diacare.25.1.127 · Cited by 113 · see citing works
Regulation of reproductive hormone secretion in primates by short-term changes in nutrition
Cameron, J. L. (1996) · Reviews of Reproduction · doi:10.1530/ror.0.0010117 · Cited by 111 · see citing works
Bone, Muscle, and Fat: Sex-related Differences in Prepubertal Children
Arfai, K., Pitukcheewanont, P., Goran, M. I., Tavaré, C. J., Heller, L., & Gilsanz, V. (2002) · Radiology · doi:10.1148/radiol.2242011369 · Cited by 110 · see citing works
Maternal factors that determine neonatal size and body fat
Catalano, P. M., & Kirwan, J. P. (2001) · Current Diabetes Reports · doi:10.1007/s11892-001-0013-y · Cited by 102 · see citing works
Rimm, E. B., Manson, J. E., Stampfer, M. J., Colditz, G. A., Willett, W. C., ROSNER, B. A., Hennekens, C. H., & Speizer, F. E. (1992) · Diabetologia · doi:10.1007/bf00401427 · Cited by 100 · see citing works
Crespo, C. J., Smit, E., Snelling, A. M., Sempos, C. T., & Andersen, R. E. (2002) · Diabetes Care · doi:10.2337/diacare.25.10.1675 · Cited by 100 · see citing works
Zhang, Y., Howard, B. V., Cowan, L. D., Yeh, J. L., Schaefer, C. F., Wild, R. A., Wang, W., & Lee, E. T. (2002) · Diabetes Care · doi:10.2337/diacare.25.3.500 · Cited by 96 · see citing works
Dietary restriction and glucose regulation in aging rhesus monkeys: a follow-up report at 8.5 yr
Gresl, T. A., Colman, R. J., Roecker, E. B., Havighurst, T. C., Huang, Z., Allison, D. B., Bergman, R. N., & Kemnitz, J. W. (2001) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2001.281.4.e757 · Cited by 93 · see citing works
Self-citationEffect of maternal weight gain on infant birth weight
Shapiro, C. R., Sutija, V. G., & Bush, J. (2000) · Journal of Perinatal Medicine · doi:10.1515/jpm.2000.056 · Cited by 93 · see citing works
A Prospective Study of Oral Contraceptives and NIDDM Among U.S. Women
Chasan‐Taber, L., Willett, W. C., Stampfer, M. J., Hunter, D. J., Colditz, G. A., Spiegelman, D. L., & Manson, J. E. (1997) · Diabetes Care · doi:10.2337/diacare.20.3.330 · Cited by 88 · see citing works
Spencer, C. P., Godsland, I. F., Cooper, A. J., Ross, D., Whitehead, M. I., & Stevenson, J. C. (2000) · Metabolism · doi:10.1053/meta.2000.6238 · Cited by 87 · see citing works
Friday, K. E., Dong, C., & Fontenot, R. U. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.1.7094 · Cited by 87 · see citing works
The North American Menopause Society (2003) · Menopause The Journal of The North American Menopause Society · doi:10.1097/00042192-200310020-00003 · Cited by 85 · see citing works
Mattiasson, I., Rendell, M., Törnquist, C., Jeppsson, S., & Hulthén, U. L. (2002) · Hormone and Metabolic Research · doi:10.1055/s-2002-35420 · Cited by 83 · see citing works
Duncan, A. C., Lyall, H., Roberts, R. N., Petrie, J. R., Perera, M., Monaghan, S., Hart, D. M., Connell, J. M. C., & Lumsden, M.-A. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.7.5836 · Cited by 82 · see citing works
Kemnitz, J. W., Goy, R. W., FLITSCH, T. J., Lohmiller, J. J., & Robinson, J. A. (1989) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-69-2-287 · Cited by 78 · see citing works
Self-citationCharacteristics of spontaneous obesity in male rhesus monkeys
Kemnitz, J. W., & Francken, G. A. (1986) · Physiology & Behavior · doi:10.1016/0031-9384(86)90414-2 · Cited by 76 · see citing works
Self-citationEffects of ovarian hormones on eating behaviors, body weight, and glucoregulation in rhesus monkeys
Kemnitz, J. W., Gibber, J. R., Lindsay, K. A., & Eisele, S. G. (1989) · Hormones and Behavior · doi:10.1016/0018-506x(89)90064-0 · Cited by 73 · see citing works
Self-citationProgestin Enhancement of the Plasma Insulin Response to Glucose in Rhesus Monkeys
Beck, P. A. (1969) · Diabetes · doi:10.2337/diab.18.3.146 · Cited by 73 · see citing works
The pharmacokinetics and efficacy of different estrogens are not equivalent
Ansbacher, R. (2001) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2001.109656 · Cited by 72 · see citing works
Oral Contraceptive Use and Association With Glucose, Insulin, and Diabetes in Young Adult Women
Kim, C., Siscovick, D. S., Sidney, S. S., Lewis, C. E., Kiefe, C. I., & Koepsell, T. D. (2002) · Diabetes Care · doi:10.2337/diacare.25.6.1027 · Cited by 70 · see citing works
The Biology of Human Fetal Growth.
Eveleth, P. B., Roberts, D. F., & Thomson, A. M. W. (1977) · Man · doi:10.2307/2801009 · Cited by 67 · see citing works
Tripathy, D., Shah, P., Lakshmy, R., & Reddy, K. (1998) · Hormone and Metabolic Research · doi:10.1055/s-2007-978950 · Cited by 66 · see citing works
The Anatomy of Adipose Tissue in Captive Macaca Monkeys and Its Implications for Human Biology
Pond, C. M., & Mattacks, C. A. (1987) · Folia Primatologica · doi:10.1159/000156293 · Cited by 64 · see citing works
Elkind-Hirsch, K. E., Sherman, L. D., & MALINAK, R. L. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.76.2.8432792 · Cited by 64 · see citing works
Obesity in Macaques: Spontaneous and Induced
Kemnitz, J. W. (1984) · Advances in veterinary science and comparative medicine · doi:10.1016/b978-0-12-039228-5.50009-7 · Cited by 61 · see citing works
Self-citationSex steroid receptors in the stomach, liver, pancreas, and gastrointestinal tract of the baboon
Winborn, W. B., Sheridan, P. J., & McGill, H. C. (1987) · Gastroenterology · doi:10.1016/0016-5085(87)90835-3 · Cited by 60 · see citing works
Cucinelli, F., Paparella, P. L., Soranna, L., Barini, A., Cinque, B., Mancuso, S., & Lanzone, A. (1999) · European Journal of Endocrinology · doi:10.1530/eje.0.1400215 · Cited by 60 · see citing works
Løkkegaard, E., Pedersen, A. T., Heitmann, B. L., Andersen, Z. J., Keiding, N., Hundrup, Y. A., Obel, E. B., & Ottesen, B. (2003) · BMJ · doi:10.1136/bmj.326.7386.426 · Cited by 59 · see citing works
Oral versus transdermal hormone replacement therapy.
Stevenson, J. C., Crook, D., Godsland, I., Lees, B., & Whitehead, M. I. (1993) · PubMed · Cited by 58 · see citing works
Andersson, B., Johannsson, G., Holm, G., Bengtsson, B., Sashegyi, A. I., Pavo, I. J., Mason, T. M., & Anderson, P. W. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.1.8168 · Cited by 57 · see citing works
Wagner, J. D., Thomas, M. J., Williams, J. K., Zhang, L., Greaves, K. A., & Cefalu, W. T. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.3.4628 · Cited by 56 · see citing works
GABAL, L., Goodman‐Gruen, D., & Barrett-Connor, E. L. (1997) · American Journal of Public Health · doi:10.2105/ajph.87.3.443 · Cited by 56 · see citing works
A quantitative and cytological study of oogenesis in the rhesus monkey.
Baker, T. G. (1966) · PubMed · Cited by 53 · see citing works
Ramsey, J. J., Laatsch, J. L., & Kemnitz, J. W. (2000) · Journal of Medical Primatology · doi:10.1034/j.1600-0684.2000.290102.x · Cited by 53 · see citing works
Self-citationBarrett-Connor, E. L., Ensrud, K. E., Harper, K. D., Mason, T. M., Sashegyi, A. I., Krueger, K. A., & Anderson, P. W. (2003) · Clinical Therapeutics · doi:10.1016/s0149-2918(03)80114-5 · Cited by 52 · see citing works
Wagner, J. D., Martino, M. A., Jayo, M. J., Anthony, M. S., Clarkson, T. B., & Cefalu, W. T. (1996) · Metabolism · doi:10.1016/s0026-0495(96)90244-9 · Cited by 52 · see citing works
The Effect of Hormone Replacement Therapy on Cardiovascular Risk Factors in Type 2 Diabetes
Manning, P. J., Allum, A. R., Jones, S., Sutherland, W. H. F., & Williams, S. (2001) · Archives of Internal Medicine · doi:10.1001/archinte.161.14.1772 · Cited by 52 · see citing works
Diabetes and Depot Medroxyprogesterone Contraception in Navajo Women
Kim, C., Seidel, K. W., Begier, E. A., & Kwok, Y. S. (2001) · Archives of Internal Medicine · doi:10.1001/archinte.161.14.1766 · Cited by 52 · see citing works
Obesity in free-ranging rhesus macaques.
Sm, S., Kemnitz, J. W., & Cf, H. (1993) · PubMed · Cited by 52 · see citing works
Self-citationGodsland, I. F., & Crook, D. (1994) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(94)05015-5 · Cited by 51 · see citing works
Postmenopausal Estrogens and Risk of Myocardial Infarction in Diabetic Women
Kaplan, R. C., Heckbert, S. R., Weiss, N. S., Wahl, P. W., Smith, N. L., Newton, K. M., & Psaty, B. M. (1998) · Diabetes Care · doi:10.2337/diacare.21.7.1117 · Cited by 48 · see citing works
Long-term effects of Depo-Provera on carbohydrate and lipid metabolism
Liew, D. F. M., Ng, C. S. A., Yong, Y. M., & Ratnam, S. S. (1985) · Contraception · doi:10.1016/0010-7824(85)90074-5 · Cited by 48 · see citing works
Friday, K. E. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.86.1.48 · Cited by 46 · see citing works
Effects of Postmenopausal Hormone Replacement Therapy on Insulin Resistance
Sağlam, K., Polat, Z., Yılmaz, M. İ., Güleç, M., & Akıncı, S. B. (2002) · Endocrine · doi:10.1385/endo:18:3:211 · Cited by 43 · see citing works
Wickman, S., Saukkonen, T. T., & Dunkel, L. (2002) · European Journal of Endocrinology · doi:10.1530/eje.0.1460339 · Cited by 43 · see citing works
Wagner, J. D. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.83.3.896 · Cited by 41 · see citing works
Sumino, H., Ichikawa, S., Itoh, H., Utsugi, T., Ohyama, Y., Umeda, M., Nakamura, T., Kanda, T., Mizunuma, H., Tomono, S., et al. (2003) · Hormone Research in Paediatrics · doi:10.1159/000072525 · Cited by 40 · see citing works
Cefalu, W. T., Wagner, J. D., Bell–Farrow, A. D., Wang, Z. Q., Adams, M. R., TOFFOLO, G. M., & Cobelli, C. (1994) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(94)90280-1 · Cited by 40 · see citing works
Age and sex differences in body size and composition during Rhesus monkey adulthood
Hudson, J. C., Baum, S. T., Frye, D. M. D., Roecker, E. B., & Kemnitz, J. W. (1996) · Aging Clinical and Experimental Research · doi:10.1007/bf03339677 · Cited by 39 · see citing works
Self-citationAmatayakul, K., Sivassomboon, B., & Singkamani, R. (1980) · Contraception · doi:10.1016/0010-7824(80)90007-4 · Cited by 39 · see citing works
Metabolic Cues for the Onset of Puberty
Cameron, J. L. (2008) · Hormone Research · doi:10.1159/000182141 · Cited by 38 · see citing works
Saad, R. J., Keenan, B. S., Danadian, K., Lewy, V. D., & Arslanian, S. A. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.10.7913 · Cited by 38 · see citing works
Androgenic influences on body size and composition of adult rhesus monkeys
Kemnitz, J. W., Sladky, K. K., FLITSCH, T. J., Pomerantz, S. M., & Goy, R. W. (1988) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1988.255.6.e857 · Cited by 38 · see citing works
Self-citationDifferential Effects of Raloxifene and Estrogen on Insulin Sensitivity in Postmenopausal Women
Lee, C. C., Kasa-Vubu, J. Z., & Supiano, M. A. (2003) · Journal of the American Geriatrics Society · doi:10.1034/j.1600-0579.2003.00214.x · Cited by 35 · see citing works
Hormone replacement therapy and glucose metabolism
TRIUSU, R. (2000) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(00)00980-7 · Cited by 35 · see citing works
The Course of Development of Glucose Intolerance in the Monkey (Macaco mulatta)
HAMILTON, C. L., & Ciaccia, P. (1978) · Journal of Medical Primatology · doi:10.1159/000459806 · Cited by 35 · see citing works
Shadoan, M., Anthony, M., Rankin, S. E., Clarkson, T. B., & Wagner, J. (2003) · Metabolism: Clinical and Experimental · doi:10.1016/s0026-0495(03)00181-1 · Cited by 34 · see citing works
Darko, D. A., Dornhorst, A., Kennedy, G., Mandeno, R., & Seed, M. (2001) · Diabetes Research and Clinical Practice · doi:10.1016/s0168-8227(01)00297-2 · Cited by 33 · see citing works
Nonhuman Primates Contribute Unique Understanding to Anovulatory Infertility in Women
Abbott, D. H., Foong, S., Bernett, D. K., & Dumesic, D. A. (2004) · ILAR Journal · doi:10.1093/ilar.45.2.116 · Cited by 33 · see citing works
Hormone replacement therapy alters insulin sensitivity in young women with premature ovarian failure
Elkind-Hirsch, K. E. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.76.2.472 · Cited by 33 · see citing works
Billiar, R. B., Richardson, D., Schwartz, R., Posner, B. I., & Little, B. (1987) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(87)80319-8 · Cited by 32 · see citing works
Snehalatha, C., Ramachandran, A., Satyavani, K., Vallabi, M. Y., & Viswanathan, V. (1997) · Metabolism · doi:10.1016/s0026-0495(97)90221-3 · Cited by 31 · see citing works
Borissova, A.-M., Tankova, T. I., Kamenova, P., Dakovska, L. N., Kovatcheva, R. D., Кirilov, G., Генов, Н., Milcheva, B., & Koev, D. (2002) · Gynecological Endocrinology · doi:10.1080/gye.16.1.67.74 · Cited by 30 · see citing works
Araújo, D. A. C., Farias, M. L. F., & Andrade, A. T. L. (2002) · Climacteric · doi:10.1080/cmt.5.3.286.292 · Cited by 30 · see citing works
EFFECT OF PROGESTINS ON GLUCOSE AND LIPID METABOLISM*
Beck, P. A. (1977) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1977.tb29435.x · Cited by 29 · see citing works
Cucinelli, F., Soranna, L., Romualdi, D., Muzj, G., Mancuso, S., & Lanzone, A. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2001-011302 · Cited by 29 · see citing works
Glucose metabolism during pregnancy: normal physiology and implications for diabetes mellitus.
Buchanan, T. (1992) · PubMed · Cited by 28 · see citing works
Sex differences in visceral adipose tissue volume among African Americans,
Sumner, A. E., Farmer, N. M., Tulloch-Reid, M. K., Sebring, N. G., Yanovski, J. A., Reynolds, J. C., Boston, R. C., & Premkumar, A. (2002) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/76.5.975 · Cited by 28 · see citing works
Lüdicke, F., GASPARD, U. J., Demeyer, F., Scheen, A. J., & Lefebvre, P. (2002) · Contraception · doi:10.1016/s0010-7824(02)00415-8 · Cited by 27 · see citing works
Complications of Pregnancy and Fetal Development
Farrell, P. M., Engle, M. J., Frantz, I. D., Goldman, A. S., Kalkhoff, R. K., Kemnitz, J. W., PERELMAN, R. H., Stern, J. S., & Susa, J. B. (1982) · Diabetes · doi:10.2337/diab.31.1.s89 · Cited by 25 · see citing works
Self-citationLewis, D. S., Bertrand, H. A., Masoro, E. J., McGill, H. C., Carey, K. D., & McMahan, C. A. (1984) · Journal of Nutrition · doi:10.1093/jn/114.11.2021 · Cited by 23 · see citing works
Jovanovic‐Peterson, L., Crues, J. V., Durak, E. P., & Peterson, C. M. (2008) · American Journal of Perinatology · doi:10.1055/s-2007-994624 · Cited by 22 · see citing works
Raudaskoski, T., Tomás, C., & Laatikainen, T. (1999) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1034/j.1600-0412.1999.780612.x · Cited by 21 · see citing works
Beck, P. A., VENABLE, R. L., & HOFF, D. L. (1975) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-41-1-44 · Cited by 21 · see citing works
Nutrition, aging and reproduction in rhesus monkeys.
Kemnitz, J. W., Holston, K. A., Colman, R. J., Hansel, W., Bray, G. A., & Donna, H. R. (1998) · Cited by 20 · see citing works
Self-citationEstrogen receptors in the islets of Langerhans of baboons
Winborn, W. B., Sheridan, P., & McGill, H. (1983) · Cell and Tissue Research · doi:10.1007/bf00216041 · Cited by 19 · see citing works
Goldzieher, J. W., Chenault, C. B., de la Peña, A., Dozier, T. S., & Kraemer, D. C. (1978) · Fertility and Sterility · doi:10.1016/s0015-0282(16)43211-5 · Cited by 19 · see citing works
Individual effect of E2 and dydrogesterone on insulin sensitivity in post-menopausal women
Soranna, L., Cucinelli, F., Perri, C., Muzj, G., Giuliani, M., Villa, P., & Lanzone, A. (2002) · Journal of Endocrinological Investigation · doi:10.1007/bf03345498 · Cited by 17 · see citing works
The influence on oral contraceptive formulation on carbohydrate and lipid metabolism.
Pw, A., Godsland, I., Melrose, J., Niththyananthan, R., Nw, O., Seed, M., & WYNN, V. (1980) · PubMed · Cited by 16 · see citing works
Localization of Progestin Receptors in the Islets of Langerhans
Winborn, W. B., Sheridan, P. J., & McGill, H. C. (1987) · Pancreas · doi:10.1097/00006676-198705000-00007 · Cited by 10 · see citing works
VELA, P., & Yen, S. S. C. (1969) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-29-9-1212 · Cited by 9 · see citing works
Tyagi, A., Rajalakshmi, M., Jeyaraj, D. A., Sharma, R. S., & Bajaj, J. S. (1999) · Contraception · doi:10.1016/s0010-7824(99)00038-4 · Cited by 7 · see citing works
Gruber (2000) · doi:10.1002/1098-2361(2000)19:3
Self-citation
Flagged first, then by citations
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Sorted by citations
Modulation of appetite by gonadal steroid hormones
Asarian, L., & Geary, N. (2006) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2006.1860 · Cited by 506 · see citing works
Sexual dimorphism in cardiometabolic health: the role of adipose tissue, muscle and liver
Goossens, G. H., Jocken, J. W. E., & Blaak, E. E. (2020) · Nature Reviews Endocrinology · doi:10.1038/s41574-020-00431-8 · Cited by 345 · see citing works
Juster, R.-P., Bizik, G., Picard, M., Arsenault-Lapierre, G., Sindi, S., Trepanier, L., Marin, M.-F., Wan, N., Sekerovic, Z., Lord, C., et al. (2011) · Development and Psychopathology · doi:10.1017/s0954579411000289 · Cited by 268 · see citing works
Body composition and cardiometabolic health across the menopause transition
Marlatt, K. L., Pitynski, D., Gavin, K. M., Moreau, K. L., Melanson, E. L., Santoro, N. F., & Kohrt, W. M. (2021) · Obesity · doi:10.1002/oby.23289 · Cited by 246 · see citing works
Old World Nonhuman Primate Models of Type 2 Diabetes Mellitus
Wagner, J. D., Kavanagh, K., Ward, G. M., Auerbach, B. J., Harwood, H. J., & Kaplan, J. R. (2006) · ILAR Journal · doi:10.1093/ilar.47.3.259 · Cited by 180 · see citing works
Roles of G protein-coupled estrogen receptor GPER in metabolic regulation
Sharma, G., Mauvais‐Jarvis, F., & Prossnitz, E. R. (2017) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2017.02.012 · Cited by 129 · see citing works
Are the available experimental models of type 2 diabetes appropriate for a gender perspective?
Franconi, F., Seghieri, G., Canu, S., Straface, E., Campesi, I., & Malorni, W. (2007) · Pharmacological Research · doi:10.1016/j.phrs.2007.11.007 · Cited by 91 · see citing works
Mechanisms IN endocrinology: metabolic syndrome through the female life cycle
Vryonidou, A., Paschou, S. A., Muscogiuri, G., Orio, F., & Goulis, D. G. (2015) · European Journal of Endocrinology · doi:10.1530/eje-15-0275 · Cited by 88 · see citing works
G-Protein-Coupled Estrogen Receptor (GPER) and Sex-Specific Metabolic Homeostasis
Sharma, G., & Prossnitz, E. R. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-70178-3_20 · Cited by 88 · see citing works
Nonhuman Primates and other Animal Models in Diabetes Research
Harwood, H. J., Listrani, P., & Wagner, J. D. (2012) · Journal of Diabetes Science and Technology · doi:10.1177/193229681200600304 · Cited by 83 · see citing works
Šimonienė, D., Platūkienė, A., Prakapienė, E., Radzevičienė, L., & Veličkienė, D. (2019) · Diabetes Therapy · doi:10.1007/s13300-019-00729-5 · Cited by 82 · see citing works
Menopausal Hormone Therapy and Cardiovascular Risk: Where are we Now?
Anagnostis, P. G., Paschou, S. Α., Katsiki, N., Krikidis, D., Lambrinoudaki, I. V., & Goulis, D. G. (2018) · Current Vascular Pharmacology · doi:10.2174/1570161116666180709095348 · Cited by 75 · see citing works
Potential contribution of insecticide exposure and development of obesity and type 2 diabetes
Xiao, X., Clark, J. M., & Park, Y. (2017) · Food and Chemical Toxicology · doi:10.1016/j.fct.2017.05.003 · Cited by 68 · see citing works
Reproductive risk factors across the female lifecourse and later metabolic health
Nichols, A. R., Chavarro, J. E., & Oken, E. (2024) · Cell Metabolism · doi:10.1016/j.cmet.2024.01.002 · Cited by 59 · see citing works
Role of estrogen receptors alpha, beta and GPER1/GPR30 in pancreatic beta-cells
Nadal, Á. (2010) · Frontiers in bioscience · doi:10.2741/3686 · Cited by 54 · see citing works
Sakboonyarat, B., Pima, W., Chokbumrungsuk, C., Pimpak, T., Khunsri, S., Ukritchon, S., Imjaijitt, W., Mungthin, M., Kaewput, W., Bhopdhornangkul, B., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-93733-4 · Cited by 56 · see citing works
Detrimental Changes in Health during Menopause: The Role of Physical Activity
Hulteen, R. M., Marlatt, K. L., Allerton, T. D., & Lovre, D. (2023) · International Journal of Sports Medicine · doi:10.1055/a-2003-9406 · Cited by 60 · see citing works
Overview of the Physiological Control of Eating
Langhans, W., & Geary, N. (2009) · Forum of nutrition/Bibliotheca Nutritio et dieta · doi:10.1159/000264392 · Cited by 48 · see citing works
Brain insulin action on peripheral insulin sensitivity in women depends on menstrual cycle phase
Hummel, J., Benkendorff, C., Fritsche, L., Prystupa, K., Vosseler, A., Gancheva, S., Trenkamp, S., Birkenfeld, A. L., Preissl, H., Roden, M., et al. (2023) · Nature Metabolism · doi:10.1038/s42255-023-00869-w · Cited by 48 · see citing works
Güldan, M., Unlu, S., Abdel‐Rahman, S. M., Özbek, L., Gaipov, A., Covic, A. S., Soler, M. J., Covic, A. C., & Kanbay, M. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13154354 · Cited by 44 · see citing works
Kleiblová, P., Springer, D., & Haluzı́k, M. (2006) · Physiological Research · doi:10.33549/physiolres.930977 · Cited by 42 · see citing works
Usefulness of the Monkey Model to Investigate the Role of Soy in Postmenopausal Women's Health
Appt, S. E. (2004) · ILAR Journal · doi:10.1093/ilar.45.2.200 · Cited by 40 · see citing works
Reproductive aging and risk for chronic disease: Insights from studies of nonhuman primates
Appt, S. E., & Ethun, K. F. (2010) · Maturitas · doi:10.1016/j.maturitas.2010.03.028 · Cited by 39 · see citing works
Impact of chronic and low cadmium exposure of rats: sex specific disruption of glucose metabolism
Jacquet, A., Arnaud, J., Hininger‐Favier, I., Hazane‐Puch, F., Couturier, K., Lénon, M., Lamarche, F., Ounnas, F., Fontaine, E. M., Moulis, J., et al. (2018) · Chemosphere · doi:10.1016/j.chemosphere.2018.05.099 · Cited by 39 · see citing works
Type 2 Diabetes--An Introduction to the Development and Use of Animal Models
Kaplan, J. R., & Wagner, J. D. (2006) · ILAR Journal · doi:10.1093/ilar.47.3.181 · Cited by 36 · see citing works
Obesity, Body Composition, and Sex Hormones: Implications for Cardiovascular Risk
Singh, P., Covassin, N., Marlatt, K. L., Gadde, K. M., & Heymsfield, S. B. (2021) · Comprehensive physiology · doi:10.1002/cphy.c210014 · Cited by 43 · see citing works
Sex and Gender Related Differences in Diabetic Kidney Disease
Sridhar, V. S., Yau, K., Benham, J. L., Campbell, D. J. T., & Cherney, D. Z. I. (2022) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2022.04.007 · Cited by 23 · see citing works
An Overview of Sex Hormones in Relation to SARS-CoV-2 Infection
Naz, M. S. G., Banaei, M., Dashti, S., & Tehrani, F. R. (2021) · Future Virology · doi:10.2217/fvl-2021-0058 · Cited by 23 · see citing works
Nutritional and Hormonal Modulation of Adiponectin and its Receptors adipoR1 and adipoR2
de Oliveira, C., de Mattos, A. B. M., Silva, C. B. R., Mota, J. F., & Zemdegs, J. C. S. (2012) · Vitamins and hormones · doi:10.1016/b978-0-12-398313-8.00003-8 · Cited by 23 · see citing works
Wu, X., Chang, Q., Zhang, Y., Zou, X., Chen, L., Zhang, L., Lv, L., & Liang, B. (2013) · Journal of Animal Physiology and Animal Nutrition · doi:10.1111/jpn.12036 · Cited by 22 · see citing works
Sex steroid hormones differentially regulate CYP2D in female wild-type and CYP2D6-humanized mice
Konstandi, M., Andriopoulou, C. E., Cheng, J., & Gonzalez, F. J. (2020) · Journal of Endocrinology · doi:10.1530/joe-19-0561 · Cited by 22 · see citing works
Diabetogenically beneficial gut microbiota alterations in third trimester of pregnancy
Amabebe, E., & Anumba, D. O. C. (2021) · Reproduction and Fertility · doi:10.1530/raf-20-0034 · Cited by 17 · see citing works
Diabetes and Obesity Research using Nonhuman Primates
Wagner, J. D., Cann, J. A., Zhang, L., & Harwood, H. J. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-381366-4.00014-6 · Cited by 17 · see citing works
Role of the Nonhuman Primate for Research Related to Women's Health
Archer, D. F. (2004) · ILAR Journal · doi:10.1093/ilar.45.2.212 · Cited by 17 · see citing works
Glucose Homeostasis, Diabetes Mellitus, and Gender-Affirming Treatment
Milionis, C., Ilias, Ι., Venaki, E., & Koukkou, E. (2023) · Biomedicines · doi:10.3390/biomedicines11030670 · Cited by 17 · see citing works
Obesity, Body Composition, and Sex Hormones: Implications for Cardiovascular Risk
Singh, P., Covassin, N., Marlatt, K. L., Gadde, K. M., & Heymsfield, S. (2022) · Comprehensive physiology · doi:10.1002/j.2040-4603.2022.tb00200.x · Cited by 16 · see citing works
Modeling Women's Health with Nonhuman Primates and Other Animals
Kaplan, J. R. (2004) · ILAR Journal · doi:10.1093/ilar.45.2.83 · Cited by 16 · see citing works
Ramírez, V., Bautista, R. J., Frausto-González, O., Rodríguez‐Peña, N., Tena‐Betancourt, E., & Bautista, C. J. (2022) · Reproductive Sciences · doi:10.1007/s43032-022-00999-8 · Cited by 14 · see citing works
Sex differences in insulin resistance in GABAB1 knockout mice
Bonaventura, M. M., Rodriguez, D., Ferreira, M. L., Crivello, M., Repetto, E. M., Bettler, B., Libertun, C., & Lux-Lantos, V. A. (2012) · Life Sciences · doi:10.1016/j.lfs.2012.11.007 · Cited by 14 · see citing works
Longitudinal dynamics of body weight change in the development of type 2 diabetes
HANSEN, B. C., Newcomb, J. D., Chen, R., & Linden, E. H. (2013) · Obesity · doi:10.1002/oby.20292 · Cited by 13 · see citing works
Meegaswatte, H., Speer, K., McKune, A. J., & Naumovski, N. (2024) · Reviews in cardiovascular medicine · doi:10.31083/j.rcm2512460 · Cited by 8 · see citing works
Aktürk, M., Törüner, F. B., Aslan, S., Altınova, A. E., Çakır, N., Elbeğ, Ş., & Arslan, M. (2013) · Gynecological Endocrinology · doi:10.3109/09513590.2013.769512 · Cited by 12 · see citing works
Tang, X., Deng, L., Xiong, H., Li, G., Lin, J., Liu, S., Xie, J., Liu, J., Kong, F., Tu, G., et al. (2014) · Europe PMC (PubMed Central) · Cited by 10 · see citing works
Yue, F., Zhang, G., Quintero, J. E., Gash, D. M., & Zhang, Z. (2017) · Experimental Gerontology · doi:10.1016/j.exger.2017.06.010 · Cited by 10 · see citing works
[Adiponectin concentrations during menstrual cycle].
Galván, R. E., Basurto, L., Saucedo, R., Campos, S., Hernández, M., & Zárate, A. (2007) · PubMed · Cited by 10 · see citing works
Sex Differences in Obesity-Related Glucose Intolerance and Insulin Resistance
Shi, H., & Kumar, S. P. D. S. (2012) · InTech eBooks · doi:10.5772/52972 · Cited by 11 · see citing works
Association of METS-IR index with psoriasis in US adults: a cross-sectional study
Liu, H., Liu, C., Wang, T., & Fang, D. (2024) · Scientific Reports · doi:10.1038/s41598-024-77784-x · Cited by 8 · see citing works
Bonding With β-Cells—A Role for Oxytocin in Glucose Handling
Scerbo, M., & Gerdes, J. (2017) · Diabetes · doi:10.2337/dbi16-0053 · Cited by 9 · see citing works
Yang, Z., Wang, Y. E., Kirschke, C. P., Stephensen, C. B., Newman, J. W. I., Keim, N. L., Cai, Y., & Huang, L. (2023) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2023.127142 · Cited by 8 · see citing works
Ebong, I., Watson, K. E., Hairston, K. G., Carnethon, M. R., Ouyang, P., Szklo, M., & Bertoni, A. G. (2016) · Maturitas · doi:10.1016/j.maturitas.2016.06.020 · Cited by 8 · see citing works
Gilis‐Januszewska, A., Bogusławska, A., Kowalik, A., Rzepka, E., Soczówka, K., Przybylik‐Mazurek, E., Głowa, B., & Hubalewska–Dydejczyk, A. (2021) · Genes · doi:10.3390/genes12101566 · Cited by 7 · see citing works
Can Lifestyle Factors of Diabetes Mellitus Patients Affect Their Fertility?
Aboua, Y. G., Oluwafemi, O., & du Plessis, S. S. (2013) · InTech eBooks · doi:10.5772/47838 · Cited by 6 · see citing works
Connolly, M., Trentalange, M. J., & Zeiss, C. J. (2016) · PubMed Central · Cited by 7 · see citing works
Lipid-lowering property of Clausena anisum-olens in hypercholesterolemic rats
Bautista, A. M., Tan, M. A., & Apostol, J. M. (2017) · Pharmaceutical Biology · doi:10.1080/13880209.2016.1260596 · Cited by 7 · see citing works
Role of human Kallistatin in glucose and energy homeostasis in mice
Sandforth, L., Brachs, S., Reinke, J., Willmes, D. M., Sancar, G., Seigner, J., Juarez-Lopez, D., Sandforth, A., McBride, J. D., Ma, J., et al. (2024) · Molecular Metabolism · doi:10.1016/j.molmet.2024.101905 · Cited by 6 · see citing works
Amiri, M., Raeisi‐Dehkordi, H., Moghtaderi, F., Zimorovat, A., Mohyadini, M., & Salehi‐Abargouei, A. (2022) · European Journal of Nutrition · doi:10.1007/s00394-022-02898-9 · Cited by 6 · see citing works
Wu, D., Jiang, W., Yang, F., Wei, S., Zhou, L., Yi, Y., Wang, H. X., Zhang, Y. A., & Yue, F. (2013) · Journal of Medical Primatology · doi:10.1111/jmp.12062 · Cited by 6 · see citing works
Rajendran, J., & Srinivasan, A. R. (2019) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2019.05.017 · Cited by 6 · see citing works
The Therapeutic Ketogenic Diet: Harnessing Glucose, Insulin, and Ketone Metabolism
Kalamian, M. (2020) · Springer eBooks · doi:10.1007/978-3-030-30730-1_22 · Cited by 5 · see citing works
Pujia, R., Maurotti, S., Coppola, A., Romeo, S., Pujia, A., & Montalcini, T. (2021) · Current Diabetes Reviews · doi:10.2174/1573399817666211005093434 · Cited by 5 · see citing works
Women with Metabolic Syndrome and Unhealthy Lifestyle Factors Are at a Higher Risk for Hyperuricemia
Kang, S., Han, K., Jung, J., Eun, Y., Kim, I. Y., Koh, E., Lee, S., Cha, H., Kim, H., & Lee, J. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12227159 · Cited by 5 · see citing works
Managing diabetes across female reproductive stages
Mauricio, D., Gratacòs, M., & Franch‐Nadal, J. (2025) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2025.02.003 · Cited by 4 · see citing works
Effect of Estradiol and Progesterone on Metabolic Biomarkers in Healthy Bitches
Tvarijonaviciute, A., Carrillo‐Sanchez, J., & Cerón, J. M. C. (2012) · Reproduction in Domestic Animals · doi:10.1111/rda.12120 · Cited by 4 · see citing works
Das, M., Chakraborty, M., Das, P., Santra, S., Mukherjee, A., Das, S., Bànyai, K., Roy, S., Choudhury, L., Gupta, R., et al. (2024) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2024.103176 · Cited by 3 · see citing works
The changes of glucose and lipid metabolism in overweight middle‐aged cynomolgus monkeys
Wu, D., Yue, F., & Zhang, Y. A. (2012) · Journal of Medical Primatology · doi:10.1111/j.1600-0684.2012.00556.x · Cited by 3 · see citing works
Aging and the Metabolic Syndrome
Ruiz-Torres, A. (2005) · Elsevier eBooks · doi:10.1016/b978-84-8174-892-5.50005-x · Cited by 2 · see citing works
Duarte, G. B. S., Cominetti, C., Sarti, F. M., Fisberg, R. M., & Rogero, M. M. (2025) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2025.127679 · Cited by 2 · see citing works
Mohammed, A., Mamoojee, Y. H., & Quinton, R. (2024) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2024.101930 · Cited by 2 · see citing works
Zhou, R., Bruns, C. M., Bird, I. M., Kemnitz, J. W., Dumesic, D. A., & Abbott, D. H. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052635 · Cited by 2 · see citing works
Self-citationLi, Y., Hong, W., Chen, P., & Zhang, Y. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1590382 · Cited by 1 · see citing works
Cardiovascular Effects of Aging in Primates—Gender Differences
Qiu, H., Depré, C., Vatner, D. E., & Vatner, S. F. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-378638-8.00018-x · Cited by 1 · see citing works
Puglisi, S. C., Mackiewicz, A. L., Ardeshir, A., Garzel, L. M., & Christe, K. L. (2021) · Comparative Medicine · doi:10.30802/aalas-cm-20-000075 · Cited by 1 · see citing works
The role of steroid hormones in skeletal muscle metabolism
Salehzadeh, F. (2011) · Figshare
Löfberg, I. E. (2020) · Jyväskylä University Digital Archive (University of Jyväskylä)
Mendes, M. F., Figueiró, M. T. O., Nunes, M. R., Pereira, R. E. D. S., Dias, I. R., Moreno, L. G., Sampaio, K. H., & Esteves, E. A. (2023) · Research Society and Development · doi:10.33448/rsd-v12i2.39334
Maghriba, G., & Damayanti, A. E. (2025) · Health & Medical Sciences · doi:10.47134/phms.v3i1.526
Sex differences in glycemic outcomes: a systematic review and meta-analysis of diabetes treatments
Liu, C., Mujahid, O., Beneyto, A., Contreras, I., & Vehı́, J. (2026) · BMJ Open Diabetes Research & Care · doi:10.1136/bmjdrc-2025-005808
Type 2 diabetes, sex and metabolic dysfunction-associated steatotic liver disease
Lonardo, A., Jamalinia, M., & Weiskirchen, R. (2026) · World Journal of Diabetes · doi:10.4239/wjd.v17.i5.119756
Struckmeyer, N., Landsberg, S., Biester, T., Dolle, R. M., Frerking, A.-K., Kapitzke, K., Knottnerus-Meyer, N., Niemeyer, M., Toenne, R., Berge, T. V. D., et al. (2026) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem-2026-0309
- Authors
- Bruns, C. M., & Kemnitz, J. W.
- Affiliations
- University of Wisconsin–Madison (US)
- ORCID
- Kemnitz, J. W.
- Venue
- ILAR Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-01-01
- Volume
- 45
- Issue
- 2
- Pages
- 160-169
- ISSN
- 1084-2020 (ISSN-L)
- OpenAlex
- W1969111819
- Semantic Scholar
- 40444bc994124530870eedd0e208bf32297d7a76
- Cited by
- 79
- References
- 128
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 7 · 2023: 6 · 2022: 5 · 2021: 8 · 2020: 4 · 2019: 2 · 2018: 2 · 2017: 6 · 2016: 2 · 2015: 1 · 2014: 1 · 2013: 5 · 2012: 7
- FWCI
- 0.38
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- ILAR Journal (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Estrogen and related hormone effects
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Keywords
- sex differences, insulin sensitivity, type 2 diabetes, sex hormones, gonadal hormones, body composition, visceral fat, glucose tolerance, ovarian hormones, menstrual cycle, pregnancy, menopause, hormone replacement therapy, estrogen, progestins, non-human primates, glucoregulation, aging
- MeSH terms
- Age Factors, Animals, Body Composition, Diabetes Mellitus, Type 2, Disease Models, Animal, Female, Glucose, Humans, Insulin, Primates, Risk Factors, Sex Factors, Gonadal Steroid Hormones, Hormone Replacement Therapy
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