The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Correlation between veterinary antimicrobial use and antimicrobial resistance in food-producing animals: a report on seven countries
Abstract
OBJECTIVES: To evaluate correlations between antimicrobial use and the prevalence of resistance in commensal Escherichia coli isolates from pigs, poultry and cattle, using data from publicly available national or international reports from seven European countries. METHODS: The link between the quantities of different classes of antimicrobials administered to food-producing animals per country (expressed in mg/population correction unit) and the prevalence of resistance to the different antimicrobial classes (interpreted by EUCAST epidemiological cut-off values) in E. coli isolates (4831 isolates in total) was assessed by means of polynomial regression analysis and determination of Spearman's rank correlation coefficient. RESULTS: A quadratic regression best fitted the antimicrobial use and antimicrobial resistance data. The coefficient of determination was, in decreasing order, 0.99 for fluoroquinolones and amphenicols, 0.94 for third-generation cephalosporins and sulphonamides, 0.93 for aminopenicillins, 0.86 for fluoroquinolones, 0.81 for streptomycin and 0.80 for gentamicin and tetracycline. Spearman's rank correlation coefficient was 1 for amphenicols, 0.96 for sulphonamides, 0.93 for streptomycin and tetracycline, 0.89 for aminopenicillins, 0.71 for gentamicin and 0.70 for third-generation cephalosporins. CONCLUSIONS: These remarkably high coefficients indicate that, at a national level, the level of use of specific antimicrobials strongly correlates to the level of resistance towards these agents in commensal E. coli isolates in pigs, poultry and cattle. However, data restraints reveal the need for further detail in collection and harmonization of antimicrobial resistance and use data in Europe.
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Cited by
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Access to effective antimicrobials: a worldwide challenge
Laxminarayan, R., Matsoso, P., Pant, S., Brower, C., Røttingen, J.-A., Klugman, K., & Davies, S. (2016) · The Lancet · doi:10.1016/s0140-6736(15)00474-2 · Cited by 1,465
Cabello, F. C., Godfrey, H. P., Buschmann, A. H., & Dölz, H. J. (2016) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(16)00100-6 · Cited by 507
The rumen microbiome: balancing food security and environmental impacts
Mizrahi, I., Wallace, R. J., & Moraïs, S. (2021) · Nature Reviews Microbiology · doi:10.1038/s41579-021-00543-6 · Cited by 490
Antibiotic use in food animals worldwide, with a focus on Africa: Pluses and minuses
Van, T. T. H., Yidana, Z., Smooker, P. M., & Coloe, P. J. (2020) · Journal of Global Antimicrobial Resistance · doi:10.1016/j.jgar.2019.07.031 · Cited by 451
Metadata
- Authors
- Chantziaras, I., Boyen, F., Callens, B., & Dewulf, J.
- Venue
- Journal of Antimicrobial Chemotherapy
- Publisher
- Oxford University Press (OUP)
- Published
- 2013-11-11
- Volume
- 69
- Issue
- 3
- Pages
- 827-834
- ISSN
- 0305-7453 (ISSN-L)
- 1460-2091
- OpenAlex
- W2164839784
- Cited by
- 622
- References
- 43
- FWCI
- 19.32
- Type
- journal article
- Language
- en
- Open access
- closed
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- Chantziaras, I., Boyen, F., Callens, B., & Dewulf, J. (2014). Correlation between veterinary antimicrobial use and antimicrobial resistance in food-producing animals: a report on seven countries. Journal of Antimicrobial Chemotherapy. https://doi.org/10.1093/jac/dkt443
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