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Cited by 743

The DOI matches its Crossref record; 184 of the 184 references it cites were found in a registry or an index.

Ribosomal proteins: functions beyond the ribosome

Open access
Zhou, Xiang, Liao, Wen-Juan, Liao, Jun-Ming, Liao, Peng, Lu, Hua·2015·Journal of Molecular Cell Biology

Abstract

Although ribosomal proteins are known for playing an essential role in ribosome assembly and protein translation, their ribosome-independent functions have also been greatly appreciated. Over the past decade, more than a dozen of ribosomal proteins have been found to activate the tumor suppressor p53 pathway in response to ribosomal stress. In addition, these ribosomal proteins are involved in various physiological and pathological processes. This review is composed to overview the current understanding of how ribosomal stress provokes the accumulation of ribosome-free ribosomal proteins, as well as the ribosome-independent functions of ribosomal proteins in tumorigenesis, immune signaling, and development. We also propose the potential of applying these pieces of knowledge to the development of ribosomal stress-based cancer therapeutics.

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Crossref · 10.1093/jmcb/mjv014

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Metadata

Authors
Zhou, X., Liao, W.-J., Liao, J.-M., Liao, P., & Lu, H.
Venue
Journal of Molecular Cell Biology
Published
2015-03-03
Volume
7
Issue
2
Pages
92-104
ISSN
  • 1674-2788 (ISSN-L)
  • 1759-4685
OpenAlex
W2113570557
Cited by
743
References
184
FWCI
15.44
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Ribosomal proteins: functions beyond the ribosome. https://app.cochat.ai/papers/10.1093/jmcb/mjv014
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Zhou, X., Liao, W.-J., Liao, J.-M., Liao, P., & Lu, H. (2015). Ribosomal proteins: functions beyond the ribosome. Journal of Molecular Cell Biology. https://doi.org/10.1093/jmcb/mjv014

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.