The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
The Vitamin D Epidemic and its Health Consequences
Open accessAbstract
Vitamin D deficiency is now recognized as an epidemic in the United States. The major source of vitamin D for both children and adults is from sensible sun exposure. In the absence of sun exposure 1000 IU of cholecalciferol is required daily for both children and adults. Vitamin D deficiency causes poor mineralization of the collagen matrix in young children's bones leading to growth retardation and bone deformities known as rickets. In adults, vitamin D deficiency induces secondary hyperparathyroidism, which causes a loss of matrix and minerals, thus increasing the risk of osteoporosis and fractures. In addition, the poor mineralization of newly laid down bone matrix in adult bone results in the painful bone disease of osteomalacia. Vitamin D deficiency causes muscle weakness, increasing the risk of falling and fractures. Vitamin D deficiency also has other serious consequences on overall health and well-being. There is mounting scientific evidence that implicates vitamin D deficiency with an increased risk of type I diabetes, multiple sclerosis, rheumatoid arthritis, hypertension, cardiovascular heart disease, and many common deadly cancers. Vigilance of one's vitamin D status by the yearly measurement of 25-hydroxyvitamin D should be part of an annual physical examination.
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Citations
Cites
Decreased bioavailability of vitamin D in obesity
Wortsman, J., Matsuoka, L. Y., Chen, T. C., Lu, Z., & Holick, M. F. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.3.690 · Cited by 3,204
Self-citation1,25-Dihydroxyvitamin D3 is a negative endocrine regulator of the renin-angiotensin system
Li, Y. C., Kong, J., Wei, M., Chen, Z.-F., Liu, S. Q., & Cao, L.-P. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0215219 · Cited by 1,625
Minireview: The OPG/RANKL/RANK System
Khosla, S. (2001) · Endocrinology · doi:10.1210/endo.142.12.8536 · Cited by 1,515
Vitamin D Receptor Expression in Human Muscle Tissue Decreases with Age
Bischoff-Ferrari, H., Borchers, M., Gudat, F., Dürmüller, U., Stähelin, H., & Dick, W. (2004) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2004.19.2.265 · Cited by 585
Holick, M. F., MacLaughlin, J. A., & Doppelt, S. H. (1981) · Science · doi:10.1126/science.6256855 · Cited by 558
Self-citationCommonly recommended daily intake of vitamin D is not sufficient if sunlight exposure is limited
Glerup, H., Mikkelsen, K., Poulsen, L., Hass, E., Overbeck, S., Thomsen, J., Charles, P., & Eriksen, E. F. (2000) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2000.00595.x · Cited by 436
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Sunlight and Vitamin D: A global perspective for health
Wacker, M., & Holick, M. F. (2013) · Dermato-Endocrinology · doi:10.4161/derm.24494 · Cited by 1,156
Self-citationDepression as a disease of modernity: explanations for increasing prevalence
Hidaka, B. H. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.12.036 · Cited by 769
Vitamin D and the occurrence of depression: causal association or circumstantial evidence?
Bertone-Johnson, E. R. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.2009.00220.x · Cited by 240
Prevalence of vitamin D inadequacy in athletes: a systematic-review and meta-analysis
Farrokhyar, F., Tabasinejad, R., Dao, D., Peterson, D., Ayeni, O. R., Hadioonzadeh, R., & Bhandari, M. (2015) · Sports Medicine · doi:10.1007/s40279-014-0267-6 · Cited by 249
Human pigmentation variation: evolution, genetic basis, and implications for public health
Parra, E. J. (2007) · American Journal of Physical Anthropology · doi:10.1002/ajpa.20727 · Cited by 191
Seasonal variations in serum 25-hydroxy vitamin D levels in a Swedish cohort
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Plausible ergogenic effects of vitamin D on athletic performance and recovery
Dahlquist, D. T., Dieter, B. P., & Koehle, M. S. (2015) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-015-0093-8 · Cited by 151
Vitamin D deficiency and sun avoidance among university students at Abu Dhabi, United Arab Emirates
Al Anouti, F., Thomas, J., Abdel-Wareth, L., Rajah, J., Grant, W. B., & Haq, A. (2011) · Dermato-Endocrinology · doi:10.4161/derm.3.4.16881 · Cited by 94
Farrokhyar, F., Sivakumar, G., Savage, K., Koziarz, A., Jamshidi, S., Ayeni, O. R., Peterson, D., & Bhandari, M. (2017) · Sports Medicine · doi:10.1007/s40279-017-0749-4 · Cited by 76
Han, Q., Li, X., Tan, Q., Shao, J., & Yi, M. (2019) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-019-0323-6 · Cited by 47
Alfawaz, H. A., Bhat, R. S., Al-Ayadhi, L., & El-Ansary, A. K. (2014) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-14-416 · Cited by 44
Changes in Body Composition with Yogurt Consumption during Resistance Training in Women
White, K. M., Bauer, S. J., Hartz, K. K., & Baldridge, M. (2009) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.19.1.18 · Cited by 35
Evolution of Skin Pigmentation Differences in Humans
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Metadata
- Authors
- Holick, M. F.
- Venue
- The Journal of Nutrition
- Publisher
- Elsevier BV
- Published
- 2005-11
- Volume
- 135
- Issue
- 11
- Pages
- 2739S-2748S
- ISSN
- 0022-3166 (ISSN-L)
- OpenAlex
- W2149175541
- Cited by
- 579
- References
- 6
- FWCI
- 18.85
- Type
- journal article
- Language
- en
- Open access
- hybrid
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