The DOI matches its Crossref record; 43 of the 44 references it cites were found in a registry or an index.
Dietary Protein and Exercise Have Additive Effects on Body Composition during Weight Loss in Adult Women
Open accessAbstract
This study examined the interaction of 2 diets (high protein, reduced carbohydrates vs. low protein, high carbohydrates) with exercise on body composition and blood lipids in women (n = 48, approximately 46 y old, BMI = 33 kg/m(2)) during weight loss. The study was a 4-mo weight loss trial using a 2 x 2 block design (Diet x Exercise). Diets were equal in total energy (7.1 MJ/d) and lipids ( approximately 30% energy intake) but differed in protein content and the ratio of carbohydrate:protein at 1.6 g/(kg . d) and <1.5 (PRO group) vs. 0.8 g/(kg . d) and >3.5 (CHO group), respectively. Exercise comparisons were lifestyle activity (control) vs. a supervised exercise program (EX: 5 d/wk walking and 2 d/wk resistance training). Subjects in the PRO and PRO + EX groups lost more total weight and fat mass and tended to lose less lean mass (P = 0.10) than the CHO and CHO + EX groups. Exercise increased loss of body fat and preserved lean mass. The combined effects of diet and exercise were additive for improving body composition. Serum lipid profiles improved in all groups, but changes varied among diet treatments. Subjects in the CHO groups had larger reductions in total cholesterol and LDL cholesterol, whereas subjects in the PRO groups had greater reductions in triacylglycerol and maintained higher concentrations of HDL cholesterol. This study demonstrated that a diet with higher protein and reduced carbohydrates combined with exercise additively improved body composition during weight loss, whereas the effects on blood lipids differed between diet treatments.
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“can also promote the loss of fat mass when higher intakes of daily protein (2-3× the RDA) are combined with an exercise program and a hypoenergetic diet.”
From International Society of Sports Nutrition Position Stand: protein and exercise (2017) · cites this paper as [40]
In the citing paper
“It has been claimed that high-protein diets may help promote weight loss, maintain lean body mass, and improve lipid and plasma glucose profiles in obese subjects with our without T2DM15, 16, 17, 18 and prevent hepatic steatosis in obese animal models.19”
Citations
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A Randomized Trial of a Low-Carbohydrate Diet for Obesity
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S UCCESSFUL W EIGHT L OSS M AINTENANCE
Wing, R. R., & Hill, J. O. (2001) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.21.1.323 · Cited by 1,382
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Samaha, F. F., Iqbal, N., Seshadri, P., Chicano, K. L., Daily, D. A., McGrory, J., Williams, T., Williams, M., Gracely, E. J., & Stern, L. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022637 · Cited by 1,267 · cited 1×
“4 g/(kg d) result in increased weight loss (6–8,12), increased loss of body fat (7,8,10), attenuated loss of fat-free mass (FFM)(4) (6,8,10,13,14), improved glycemic control (6,10–12), improved blood lipid profiles (10,12,16,17), and enhanced satiety (15).”
BackgroundYang, W.-S., Lee, W.-J., Funahashi, T., Tanaka, S., Matsuzawa, Y., Chao, C.-L., Chen, C.-L., Tai, T.-Y., & Chuang, L.-M. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.86.8.3815 · Cited by 1,181
Research works printed but not linked: 1
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European Guidelines for Obesity Management in Adults
Yumuk, V., Tsigos, C., Fried, M., Schindler, K., Busetto, L., Micic, D., & Toplak, H. (2015) · Obesity Facts · doi:10.1159/000442721 · Cited by 3,432
DONNELLY, J. E., BLAIR, S. N., JAKICIC, J. M., MANORE, M. M., RANKIN, J. W., & SMITH, B. K. (2009) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181949333 · Cited by 2,658
Houston, D. K., Nicklas, B. J., Ding, J., Harris, T. B., Tylavsky, F. A., Newman, A. B., Lee, J. S., Sahyoun, N. R., Visser, M., & Kritchevsky, S. B. (2008) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.1.150 · Cited by 1,214
International Society of Sports Nutrition Position Stand: protein and exercise
Jäger, R., Kerksick, C. M., Campbell, B. I., Cribb, P. J., Wells, S. D., Skwiat, T. M., Purpura, M., Ziegenfuss, T. N., Ferrando, A. A., Arent, S. M., et al. (2017) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-017-0177-8 · Cited by 873
“As a classic example, Layman and investigators [40] randomized obese women to consume one of two restricted energy diets (1600–1700 kcals/day) that were either higher in carbohydrates (>3.”
Dietary protein intake and human health
Wu, G. (2016) · Food & Function · doi:10.1039/c5fo01530h · Cited by 748
Metadata
- Authors
- Layman, D. K., Evans, E., Baum, J. I., Seyler, J., Erickson, D. J., & Boileau, R. A.
- Affiliations
- University of Illinois Urbana-Champaign (US)
- Corresponding author
- Layman, Donald K.
- Venue
- The Journal of Nutrition
- Publisher
- Elsevier BV
- Published
- 2005-08
- Volume
- 135
- Issue
- 8
- Pages
- 1903-1910
- ISSN
- 0022-3166 (ISSN-L)
- OpenAlex
- W2165340329
- Cited by
- 330
- References
- 44
- Citations by year
- 2026: 5 · 2025: 4 · 2024: 9 · 2023: 7 · 2022: 9 · 2021: 5 · 2020: 17 · 2019: 9 · 2018: 15 · 2017: 15 · 2016: 19 · 2015: 26 · 2014: 25 · 2013: 20 · 2012: 25
- FWCI
- 6.25
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
- Health Sciences › Medicine › Physiology (medical) › Diet and metabolism studies
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Keywords
- dietary protein, physical activity, body composition, weight loss, high-protein diet, low-carbohydrate diet, fat mass, lean body mass, serum lipids, cholesterol, triglycerides, HDL cholesterol, resistance training, walking, women
- MeSH terms
- Adult, Body Composition, Energy Intake, Dietary Carbohydrates, Dietary Proteins, Female, Humans, Life Style, Middle Aged, Weight Loss, Exercise, Body Mass Index, Diet, Protein-Restricted
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