Cited by 176Cerebrospinal fluid and hydrocephalusBarrier Structure and Function StudiesIon Transport and Channel Regulation

The DOI matches its Crossref record; 267 of the 267 references it cites were found in a registry or an index.

The Choroid Plexus in Healthy and Diseased Brain

Kaur, Charanjit, Rathnasamy, Gurugirijha, Ling, Eng-Ang·2016·Journal of Neuropathology & Experimental Neurology

DOI 10.1093/jnen/nlv030

Open this paper in CoChat — free account

Abstract

The choroid plexus is composed of epithelial cells resting on a basal lamina. These cells produce the cerebrospinal fluid (CSF), which has many functions including rendering mechanical support, providing a route for some nutrients, removing by-products of metabolism and synaptic activity, and playing a role in hormonal signaling. The choroid plexus synthesizes many growth factors, including insulin-like, fibroblast, and platelet-derived growth factors. The tight junctions located between the apical parts of the choroid plexus epithelial cells form the blood-CSF barrier (BCSFB), which is crucial for the homeostatic regulation of the brain microenvironment along with the blood-brain barrier (BBB). Morphological changes such as atrophy of the epithelial cells and thickening of the basement membrane suggest altered CSF production occurs in aging and in Alzheimer disease. In brain injuries and infections, leukocytes accumulate in the CSF by passing through the choroid plexus. In inflammatory CNS diseases (eg, multiple sclerosis), pathogenic autoreactive T lymphocytes may migrate through the BBB and BCSFB into the CNS. The development of therapeutic strategies to mitigate disruption of the BCSFB may be helpful to curtail the entry of inflammatory cells into the CSF and hence reduce inflammation, thereby overcoming choroid plexus dysfunction in senescence and in various diseases of the CNS.

Integrity signals

Registry

Crossref · 10.1093/jnen/nlv030

Cites

267 of 267 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Items 201–267 of 267

Vasopressin in vascular regulation and water homeostasis in the brain.
Koźniewska, E., & Romaniuk, K. (2008) · PubMed · Cited by 48
Vascular Endothelial Growth Factor and Nitric Oxide Production in Response to Hypoxia in the Choroid Plexus in Neonatal Brain
Viswanathan, S., Lu, J., Ling, E., & Kaur, C. (2007) · Brain Pathology · doi:10.1111/j.1750-3639.2007.00104.x · Cited by 48
Self-citation
Functional and genetic analysis of choroid plexus development in zebrafish
Henson, H. E., Parupalli, C., Ju, B., & Taylor, M. R. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00364 · Cited by 46
Early Developmental Changes in IGF-I, IGF-II, IGF Binding Protein-1, and IGF Binding Protein-3 Concentration in the Cerebrospinal Fluid of Children
Bunn, R. C., King, W. D., Winkler, M. K., & Fowlkes, J. L. (2005) · Pediatric Research · doi:10.1203/01.pdr.0000156369.62787.96 · Cited by 46
Classification of the cerebral edemas with reference to hydrocephalus and pseudotumor cerebri
Milhorat, T. H. (1992) · Child s Nervous System · doi:10.1007/bf00296558 · Cited by 45
Vasopressin mediates the inhibitory effect of central angiotensin II on cerebrospinal fluid formation
Chodobski, A., Szmydynger‐Chodobska, J., & Johanson, C. E. (1998) · European Journal of Pharmacology · doi:10.1016/s0014-2999(98)00229-5 · Cited by 45
Altered cellular localization of aquaporin-1 in experimental hydrocephalus in mice and reduced ventriculomegaly in aquaporin-1 deficiency
Wang, D., Nykänen, M., Yang, N., et al. (2010) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2010.10.003 · Cited by 44
Hydrocephalus and aquaporins: lessons learned from the bench
Filippidis, A., Kalani, M. Y. S., & Rekate, H. L. (2010) · Child s Nervous System · doi:10.1007/s00381-010-1227-6 · Cited by 44
Neuroprotective effects of TGF-beta 1.
Henrich‐Noack, P., Prehn, J. H. M., & Krieglstein, J. (1994) · PubMed · Cited by 44
Distinct Sites of Insulin-Like Growth Factor (IGF)-II Expression and Localization in Lesioned Rat Brain: Possible Roles of IGF Binding Proteins (IGFBPs) in the Mediation of IGF-II Activity
Walter, H. J. (1999) · Endocrinology · doi:10.1210/en.140.1.520 · Cited by 44
Comparison of ventricular and lumbar cerebrospinal fluid T cells in non-inflammatory neurological disorder (NIND) patients
Provencio, J. J., Kivisäkk, P., Tucky, B. H., Luciano, M. G., & Ransohoff, R. M. (2005) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2005.03.003 · Cited by 43
Transthyretin-Derived Peptides as β-Amyloid Inhibitors
Cho, P. Y., Gururaj Joshi, A., Johnson, J. A., & Murphy, R. M. (2014) · ACS Chemical Neuroscience · doi:10.1021/cn500014u · Cited by 43
Autocrine Role of Insulin‐like Growth Factor II Secretion by the Rat Choroid Plexus
Nilsson, C. F., Hultberg, B. M., & Gammeltoft, S. (1996) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1996.tb01248.x · Cited by 41
Vectorial Ligand Transport Through Mammalian Choroid Plexus
Spector, R., & Johanson, C. E. (2010) · Pharmaceutical Research · doi:10.1007/s11095-010-0162-2 · Cited by 40
Central origin of IL-1β produced during peripheral inflammation: role of meninges
Garabedian, B. V.-D., Lemaigre‐Dubreuil, Y., & Mariani, J. (2000) · Molecular Brain Research · doi:10.1016/s0169-328x(99)00320-4 · Cited by 40
Involvement of choroid plexus in mitochondrial encephalomyopathy (MELAS)
Ohama, E., & Ikuta, F. (1987) · Acta Neuropathologica · doi:10.1007/bf00686785 · Cited by 40
Ceftriaxone pharmacokinetics in the central nervous system.
Spector, R. (1986) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)38906-8 · Cited by 39
Expression of glial cell line‐derived neurotrophic factor in the brain and cerebrospinal fluid of the developing rat
Ikeda, T., Xia, X. Y., Xia, Y. X., Ikenoue, T., & Choi, B. H. (1999) · International Journal of Developmental Neuroscience · doi:10.1016/s0736-5748(99)00057-x · Cited by 39
Disruption of the blood-cerebrospinal fluid barrier by transient cerebral ischemia
Nagahiro, S., Goto, S., Korematsu, K., Sumi, M., Takahashi, M., & Ushio, Y. (1994) · Brain Research · doi:10.1016/0006-8993(94)91553-9 · Cited by 39
Oncocytic transformation of choroid plexus epithelium
Kepes, J. J. (1983) · Acta Neuropathologica · doi:10.1007/bf00684932 · Cited by 38
Physiological Roles of Aquaporins in the Choroid Plexus
Boassa, D., & Yool, A. J. (2005) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(05)67005-6 · Cited by 37
Elektronenmikroskopische Untersuchung der Entwicklung der telencephalen Plexus chorioides des Huhnes
Meller, K., & Wechsler, W. (1965) · Cell and Tissue Research · doi:10.1007/bf00345641 · Cited by 37
Intracellular neurofibrillary tangle-like aggregations. A constantly present amyloid alteration in the aging choroid plexus.
Eriksson, L. G., & Westermark, P. (1986) · PubMed Central · Cited by 37
A Novel Porcine In Vitro Model of the Blood-Cerebrospinal Fluid Barrier with Strong Barrier Function
Schroten, M., Hanisch, F., Quednau, N., Stump-Guthier, C., Riebe, R., Lenk, M., Wolburg, H., Tenenbaum, T., & Schwerk, C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0039835 · Cited by 36
Ultrastructure and mode of formation of epiplexus cells in the choroid plexus in the lateral ventricles of the monkey (Macaca fascicularis).
Ea, L. (1981) · PubMed · Cited by 35
The transcription factors Emx1 and Emx2 suppress choroid plexus development and promote neuroepithelial cell fate
von Frowein, J., Wizenmann, A., & Götz, M. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.04.461 · Cited by 35
Decrease of Transthyretin Synthesis at the Blood-Cerebrospinal Fluid Barrier of Old Sheep
Chen, R. L., Athauda, S. B. P., Kassem, N. A., Zhang, Y., Segal, M. B., & Preston, J. E. (2005) · The Journals of Gerontology Series A · doi:10.1093/gerona/60.7.852 · Cited by 33
Development of blood-cerebrospinal fluid barrier to horseradish peroxidase in the avian choroidal epithelium
Wakai, S., & Hirokawa, N. (1981) · Cell and Tissue Research · doi:10.1007/bf00249211 · Cited by 32
VEGF/VEGFR-2 changes in frontal cortex, choroid plexus, and CSF after chronic obstructive hydrocephalus
Yang, J., Dombrowski, S. M., Deshpande, A., et al. (2010) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2010.06.012 · Cited by 32
Choroid plexus electrolytes and ultrastructure following transient forebrain ischemia
Palm, D. E., Knuckey, N., Guglielmo, M., Watson, P., Primiano, M. J., & Johanson, C. E. (1995) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1995.269.1.r73 · Cited by 32
Insulin-like growth factor-1 and insulin-like growth factor binding proteins in cerebrospinal fluid during the development of mouse embryos
Salehi, Z., Mashayekhi, F., Naji, M., & Pandamooz, S. (2009) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2008.09.018 · Cited by 31
Effect of Small Molecule Vasopressin V 1a and V 2 Receptor Antagonists on Brain Edema Formation and Secondary Brain Damage following Traumatic Brain Injury in Mice
Krieg, S. M., Sonanini, S., Plesnila, N., & Trabold, R. (2014) · Journal of Neurotrauma · doi:10.1089/neu.2013.3274 · Cited by 31
Transmigration of macrophages across the choroid plexus epithelium in response to the feline immunodeficiency virus
Meeker, R. B., Bragg, D. C., Poulton, W., & Hudson, L. C. (2012) · Cell and Tissue Research · doi:10.1007/s00441-011-1301-8 · Cited by 30
Arginine Vasopressin V 1a Receptor-Deficient Mice Have Reduced Brain Edema and Secondary Brain Damage following Traumatic Brain Injury
Rauen, K., Trabold, R., Brem, C., Terpolilli, N. A., & Plesnila, N. (2013) · Journal of Neurotrauma · doi:10.1089/neu.2012.2807 · Cited by 30
Tight junction proteins vary in the choroid plexus of ewes according to photoperiod
Lagaraine, C., Skipor, J., Szczepkowska, A., Dufourny, L., & Thiéry, J. (2011) · Brain Research · doi:10.1016/j.brainres.2011.04.009 · Cited by 29
Regulatory volume increase in epithelial cells isolated from the mouse fourth ventricle choroid plexus involves Na+–H+ exchange but not Na+–K+–2Cl− cotransport
Hughes, A. L. H., Пахомова, А. Н., & Brown, P. D. N. (2010) · Brain Research · doi:10.1016/j.brainres.2009.12.094 · Cited by 29
Expression of glial cell line‐derived neurotrophic factor (GDNF) in the developing human fetal brain
Koo, H., & Choi, B. (2001) · International Journal of Developmental Neuroscience · doi:10.1016/s0736-5748(01)00042-9 · Cited by 28
Characterization of Prolactin Receptors in Human Choroid Plexus
Lai, Z., Roos, P., Olsson, Y., et al. (2008) · Neuroendocrinology · doi:10.1159/000126232 · Cited by 28
Impairment of blood–cerebrospinal fluid barrier properties by retrovirus‐activated T lymphocytes: reduction in cerebrospinal fluid‐to‐blood efflux of prostaglandin E2
Khuth, S. T., Strazielle, N., Giraudon, P., Belin, M., & Ghersi‐Egea, J. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03309.x · Cited by 26
Morphological modifications of the choroid plexus in a rodent model of acute ventriculitis induced by gram-negative liquoral sepsis
Cardia, E., Molina, D., Abbate, F., et al. (1995) · Child s Nervous System · doi:10.1007/bf00822840 · Cited by 26
Effect of endogenous vasopressin on blood flow to choroid plexus during hypoxia and intracranial hypertension
Faraci, F. M., Kinzenbaw, D. A., & Heistad, D. D. (1994) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1994.266.2.h393 · Cited by 25
Neuroinflammation Induced by Intracerebroventricular Injection of Microbial Neuraminidase
Granados‐Durán, P., López-Ávalos, M. D., Grondona, J. M., Gómez-Roldán, M. D. C., Cifuentes, M., Pérez‐Martín, M., Álvarez, M., de Fonseca, F. R., & Fernández‐Llebrez, P. (2015) · Frontiers in Medicine · doi:10.3389/fmed.2015.00014 · Cited by 24
Salt-loading increases vasopressin and vasopressin 1b receptor mRNA in the hypothalamus and choroid plexus
Zemo, D. A., & McCabe, J. T. (2001) · Neuropeptides · doi:10.1054/npep.2001.0864 · Cited by 24
Different expressions of AQP1, AQP4, eNOS, and VEGF proteins in ischemic versus non-ischemic cerebropathy in rats: potential roles of AQP1 and eNOS in hydrocephalic and vasogenic edema formation
Kim, J. H., & Jung, Y. (2011) · Anatomy & Cell Biology · doi:10.5115/acb.2011.44.4.295 · Cited by 24
Immunohistochemical localization of transforming growth factor-α in choroid plexus of the rat and chicken
Díaz-Ruiz, C., Pérez‐Tomás, R., Domingo, J., et al. (1993) · Neuroscience Letters · doi:10.1016/0304-3940(93)90853-d · Cited by 23
Expression and upregulation of transferrin receptors and iron uptake in the epiplexus cells of different aged rats injected with lipopolysaccharide and interferon-gamma.
Lu, J., Kaur, C., & Ling, E. (1995) · PubMed · Cited by 22
Self-citation
Distribution of fibroblast growth factor receptors and their co-localization with vasopressin in the choroid plexus epithelium
Szmydynger‐Chodobska, J., Chun, Z. G., Johanson, C. E., et al. (2002) · Neuroreport · doi:10.1097/00001756-200202110-00017 · Cited by 21
Characterization of multiple first exons in murine prolactin receptor gene and the effect of prolactin on their expression in the choroid plexus
Tabata, H., Kobayashi, M., Ikeda, J. H., et al. (2012) · Journal of Molecular Endocrinology · doi:10.1530/jme-11-0122 · Cited by 21
Effect of arginine vasopressin on the cortex edema in the ischemic stroke of Mongolian gerbils
Zhao, X.-Y., Wu, C.-F., Yang, J., Gao, Y., Sun, F.-J., Wang, D., Wang, C., & Lin, B.-C. (2015) · Neuropeptides · doi:10.1016/j.npep.2015.01.003 · Cited by 20
Detection of Growth Hormone Receptor mRNA in an Ovine Choroid Plexus Epithelium Cell Line
Thörnwall, M., Chhajlani, V., Legreves, P., et al. (1995) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1995.2783 · Cited by 20
Psammoma bodies – Friends or foes of the aging choroid plexus
Jovanovic, I. D., Ugrenović, S., Vasović, L. P., Petrović, D., & Cekić, S. (2010) · Medical Hypotheses · doi:10.1016/j.mehy.2010.01.006 · Cited by 19
Expression of the Nrf2‐system at the blood‐CSF barrier is modulated by neonatal inflammation and hypoxia‐ischemia
D’Angelo, B., Ek, C. J., Sandberg, M., & Mallard, C. E. (2012) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-012-9551-5 · Cited by 18
Transthyretin is not necessary for thyroid hormone metabolism in conditions of increased hormone demand
Sousa, J. C., de Escobar, G. M., Oliveira, P., Saraiva, M. J., & Palha, J. A. (2005) · Journal of Endocrinology · doi:10.1677/joe.1.06406 · Cited by 18
Mitochondrial abnormalities in choroid plexus of leigh disease
Ohama, E., Ikuta, F., & Nakamura, N. (1988) · Brain and Development · doi:10.1016/s0387-7604(88)80042-1 · Cited by 17
Cerebrospinal fluid dynamics in the newborn dog during normoxia and hypoxia
Holloway, L. S., & Cassin, S. (1972) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1972.223.3.499 · Cited by 17
Ultrastructural Characteristics of the Telencephalic and Myelencephalic Choroid Plexuses in Fetus of Man and Rabbit, and a Comparison with the Adult Choroid Plexus in Rabbit
Tennyson, V. M. (1975) · Elsevier eBooks · doi:10.1016/b978-0-7236-0363-4.50008-9 · Cited by 17
On the development, structure and function of the paraphysis cerebri.
Ariens Kappers, J. (1956) · PubMed · Cited by 16
Studies of activated microglial cells and macrophages using Alzheimer's disease cerebrospinal fluid in adult rats with experimentally induced lesions
Ling, E. A., Dahlström, A. B., Polinsky, R. J., Nee, L. E., & McRae‐Degueurce, A. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90522-4 · Cited by 15
Self-citation
Choroidal Proteins Involved in Cerebrospinal Fluid Production may be Potential Drug Targets for Alzheimer's Disease Therapy
Wostyn, P., Audenaert, K., & Deyn, P. P. D. (2011) · Perspectives in Medicinal Chemistry · doi:10.4137/pmc.s6509 · Cited by 15
Evidence for increased calcium influx across the choroid plexus following brief ischemia of gerbil brain
Ikeda, J., Mies, G., Nowak, T. S., et al. (1992) · Neuroscience Letters · doi:10.1016/0304-3940(92)90386-l · Cited by 13
Toxic Shock Syndrome Toxin–1 Challenges the Neuroprotective Functions of the Choroidal Epithelium and Induces Neurotoxicity
Batisson, M., Strazielle, N., Hejmadi, M. V., Thomas, D. Y., Ghersi‐Egea, J., Étienne, J., Vandenesch, F., & Lina, G. (2006) · The Journal of Infectious Diseases · doi:10.1086/505428 · Cited by 13
Iron Transport in the Central Nervous System
Burdo, J. R., & Connor, J. (2002) · CRC Press eBooks · doi:10.1201/9780824744175.ch20 · Cited by 13
Vasopressin, hypothalamo–neurohypophyseal system and aging
Frolkis, V. V., Kvitnitskaya-Ryzhova, T., & Dubiley, T. A. (2000) · Archives of Gerontology and Geriatrics · doi:10.1016/s0167-4943(99)00032-1 · Cited by 12
Ultrastructural study of the lateral ventricle choroid plexus in experimental hydrocephalus in Wistar rats
Tirapelli, D. P. D. C., Lopes, L. D. S., Lachat, J. J., et al. (2007) · Arquivos de Neuro-Psiquiatria · doi:10.1590/s0004-282x2007000600010 · Cited by 10
Co-localization and regulation of basic fibroblast growth factor and arginine vasopressin in neuroendocrine cells of the rat and human brain
Gonzalez, A. M., Taylor, W. M., Johanson, C. E., et al. (2010) · Cerebrospinal Fluid Research · doi:10.1186/1743-8454-7-13 · Cited by 8
Ultrastructure and mode of formation of epiplexus cells in the choroid plexus in the lateral ventricles of the monkey (Macaca fascicularis)
Ling, E. A. (1981) · National University of Singapore · Cited by 7
Self-citation
Response of epithelial cells of the choroid plexus in the ferret model for Reye's syndrome.
Rarey, K. E., Ja, D., & Deshmukh, D. R. (1987) · PubMed · Cited by 6

Research works printed but not linked: 8

10.1002/1097-0029(20010101)52:1<49::AID-JEMT7>3.0.CO;2-C · DOI
10.1210/en.135.5.2275 · DOI
10.1210/en.141.4.1434 · DOI
10.1002/1097-0029(20010101)52:1<65::AID-JEMT9>3.0.CO;2-4 · DOI
Hayamizu, 1999, The role of FGF-2 in the response to cerebral ischemia: FGF-2 expression in the hippocampus and choroid plexus, and the neuroprotective effects of intraventricular FGF-2 infusion in a rat model of transient forebrain ischemia, 25, 1851
Kolmer, 1921, Über eine eigenartige Beziehung von Wanderzellen zu dem Choroidalplexus des Gehirns der Wirbeltiere, Anat Anz, 54, 15
10.1002/1097-0029(20010101)52:1<112::AID-JEMT13>3.0.CO;2-5 · DOI
10.1002/1097-0029(20010101)52:1<31::AID-JEMT5>3.0.CO;2-T · DOI

Sorted by citations

The anatomy and immunology of vasculature in the central nervous system
Mastorakos, P., & McGavern, D. (2019) · Science Immunology · doi:10.1126/sciimmunol.aav0492 · Cited by 333
Translational value of choroid plexus imaging for tracking neuroinflammation in mice and humans
Fleischer, V., Gonzalez-Escamilla, G., Ciolac, D., Albrecht, P., Küry, P., Gruchot, J., Dietrich, M., Hecker, C., Müntefering, T., Bock, S., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2025000118 · Cited by 152
Klotho controls the brain-immune system interface in the choroid plexus
Zhu, L., Stein, L. R., Kim, D., Ho, K., Yu, G.-Q., Zhan, L., Larsson, T. E., & Mucke, L. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1808609115 · Cited by 148
Hello from the other side: how autoantibodies circumvent the blood-brain barrier in autoimmune encephalitis
Platt, M. P., Agalliu, D., & Cutforth, T. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00442 · Cited by 108
Molecular and cellular aspects of age-related cognitive decline and Alzheimer’s disease
Hullinger, R., & Puglielli, L. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.05.008 · Cited by 68

See all 176

Authors: Kaur, C., Rathnasamy, G., & Ling, E.-A.
Affiliations: National University of Singapore (SG)
ORCID: Kaur, Charanjit
Rathnasamy, Gurugirijha
Ling, Eng-Ang
Venue: Journal of Neuropathology & Experimental Neurology
Publisher: Oxford University Press (OUP)
Published: 2016-02-17
Volume: 75
Issue: 3
Pages: 198-213
ISSN: 0022-3069 (ISSN-L)
1554-6578
DOI: 10.1093/jnen/nlv030
OpenAlex: W2281330516
Cited by: 176
References: 267
Citations by year: 2026: 16 · 2025: 22 · 2024: 21 · 2023: 14 · 2022: 21 · 2021: 27 · 2020: 14 · 2019: 22 · 2018: 5 · 2017: 11 · 2016: 3
FWCI: 1.50
Type: journal article
Language: en
Open access: closed
Locations: Journal of Neuropathology & Experimental Neurology (publishedVersion)
PubMed (publishedVersion)
HighWire Press Open Archive (submittedVersion)
Topics: Health Sciences › Medicine › Clinical Neurology › Cerebrospinal fluid and hydrocephalus
Life Sciences › Neuroscience › Neurology › Barrier Structure and Function Studies
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion Transport and Channel Regulation
Keywords: choroid plexus, cerebrospinal fluid production, blood-CSF barrier, choroid plexus epithelial cells, tight junctions, growth factors, aging, Alzheimer's disease, brain injury, central nervous system infection, multiple sclerosis, autoreactive T cells, leukocyte transmigration, blood-brain barrier
MeSH terms: Animals, Blood-Brain Barrier, Brain Diseases, Choroid Plexus, Humans, Tight Junctions

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The Choroid Plexus in Healthy and Diseased Brain

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks