Trajectories of adherence to airway clearance therapy for patients with cystic fibrosis
Abstract
OBJECTIVE: Although cross-sectional studies have demonstrated poor adherence to airway clearance therapy (ACT) for patients with cystic fibrosis (CF), no studies have identified longitudinal patterns of adherence. The objective was to characterize and identify predictors of ACT adherence trajectories for individuals with CF. METHODS: Secondary data analyses were conducted for a randomized clinical trial examining differences in three ACTs. Participants (n = 153; M = 14.3 years, 55% male, 86% Caucasian, baseline FEV(1)% predicted: M = 86.7)/primary caregivers completed Daily Phone Diaries, an empirically supported adherence measure, every 4 months. RESULTS: Group-based trajectory modeling revealed the best-fitting solution was a three-group model: low-adherence (14%), medium-adherence (49%), and high-adherence (37%) groups. ACT type was the only significant predictor of adherence trajectories. DISCUSSION: Three trajectories of adherence to ACT for patients with CF were found. With the identification of trajectories, adherence interventions can be targeted for the subgroup at highest risk in order to prevent poor health outcomes.
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Modi 2010 describes an RCT comparing three airway secretion clearance therapies in CF (postural drainage and percussion, flutter device, or high frequency chest wall oscillation), so it is not focused on improving adherence to inhaled therapies.
“Modi 2010 This study describes an RCT comparing three airway secretion clearance therapies in CF: 1) postural drainage and percussion, 2) flutter device or 3) high frequency chest wall oscillation -i.e. it is not focused on improving adherence to inhaled therapies.”
From Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis (2023) · cites this paper as Modi 2010
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Pain and Health-Related Quality of Life in Adolescents with Cystic Fibrosis
Blackwell, L. S. (2013)
Rubin, B. K. (2017) · Respiratory Care · doi:10.4187/respcare.05511
Psychology and Psychotherapy in CF
Nutting, R., & Amos, S. P. (2020) · Springer eBooks · doi:10.1007/978-3-030-25909-9_15
Parents' experience of physiotherapy for infants with Cystic Fibrosis: A qualitative study
Andrews, K. (2020) · Charles Sturt University Research Output (CRO)
Sherman, A. C., O’Brien, C. E., & Simonton-Atchley, S. (2024) · International Journal of Behavioral Medicine · doi:10.1007/s12529-024-10306-1
- Authors
- Modi, A. C., Cassedy, A. E., Quittner, A. L., Accurso, F., Sontag, M., Koenig, J. M., & Ittenbach, R. F.
- Affiliations
- Cincinnati Children's Hospital Medical Center (US)
- Venue
- Journal of Pediatric Psychology
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-03-18
- Volume
- 35
- Issue
- 9
- Pages
- 1028-1037
- ISSN
- 0146-8693 (ISSN-L)
- 1465-735X
- OpenAlex
- W2148119059
- Cited by
- 72
- References
- 34
- Citations by year
- 2025: 2 · 2024: 2 · 2023: 5 · 2022: 2 · 2021: 3 · 2020: 9 · 2019: 5 · 2018: 5 · 2017: 5 · 2016: 7 · 2015: 7 · 2014: 8 · 2013: 6 · 2012: 3
- FWCI
- 3.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Pediatric Psychology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cystic Fibrosis Research Advances
- Health Sciences › Health Professions › Speech and Hearing › Adolescent and Pediatric Healthcare
- Keywords
- cystic fibrosis, airway clearance therapy, medication adherence, adherence trajectories, group-based trajectory modeling, predictors of adherence, pediatric patients, adherence interventions
- MeSH terms
- Adolescent, Cystic Fibrosis, Female, Health Status, Humans, Male, Patient Compliance, Surveys and Questionnaires, Respiratory Function Tests, Respiratory Therapy
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