The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Treatment Adherence in Adolescents With Inflammatory Bowel Disease: The Collective Impact of Barriers to Adherence and Anxiety/Depressive Symptoms
Open accessAbstract
OBJECTIVE: Knowledge of factors impacting adolescents' ability to adhere to their inflammatory bowel disease (IBD) regimen is limited. The current study examines the collective impact of barriers to adherence and anxiety/depressive symptoms on adolescent adherence to the IBD regimen. METHODS: Adolescents (n = 79) completed measures of barriers to adherence, adherence, and anxiety/depressive symptoms at one of two specialty pediatric IBD clinics. RESULTS: Most adolescents reported barriers to adherence and 1 in 8 reported borderline or clinically elevated levels of anxiety/depressive symptoms. Anxiety/depressive symptoms moderated the relationship between barriers to adherence and adherence. Post hoc probing revealed a significant, additive effect of higher anxiety/depressive symptoms in the barriers-adherence relationship, with adherence significantly lower among adolescents with higher barriers and higher anxiety/depressive symptoms. CONCLUSIONS: In order to optimize adherence in adolescents, interventions should target not only barriers to adherence but also any anxiety/depressive symptoms that may negatively impact efforts to adhere to recommended treatment.
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“Indeed, comorbid psychological difficulties are associated with disease activity, flares, treatment response, and the necessity of surgical intervention [2,6,8,9,10,11,12,13,14,15].”
From Brief and Telehealth Acceptance and Commitment Therapy (ACT) Interventions for Stress in Inflammatory Bowel Disease (IBD): A Series of Single Case Experimental Design (SCED) Studies (2022) · cites this paper as [11]
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Metadata
- Authors
- Gray, W. N., Denson, L. A., Baldassano, R. N., & Hommel, K. A.
- Affiliations
- Cincinnati Children's Hospital Medical Center (US)
- Venue
- Journal of Pediatric Psychology
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-11-10
- Volume
- 37
- Issue
- 3
- Pages
- 282-291
- ISSN
- 0146-8693 (ISSN-L)
- 1465-735X
- PMC
- PMC3306169
- OpenAlex
- W2142245641
- Cited by
- 143
- References
- 53
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 7 · 2023: 16 · 2022: 9 · 2021: 14 · 2020: 12 · 2019: 9 · 2018: 11 · 2017: 13 · 2016: 10 · 2015: 10 · 2014: 10 · 2013: 13 · 2012: 3
- FWCI
- 7.65
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Pediatric Psychology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Procter and Gamble
- National Institutes of Health (5ul1rr026314-03, UL1TR000077, 1UL1RR026314)
- National Institute of Diabetes and Digestive and Kidney Diseases (K23DK079037)
- National Center for Research Resources (1UL1RR026314, UL1-RR026314)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Adolescent and Pediatric Healthcare
- Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
- Keywords
- inflammatory bowel disease, adolescents, medication adherence, barriers to adherence, anxiety symptoms, depressive symptoms, psychosocial factors, pediatric inflammatory bowel disease
- MeSH terms
- Adolescent, Adolescent Behavior, Anxiety, Colitis, Ulcerative, Crohn Disease, Depression, Female, Humans, Male, Severity of Illness Index, Inflammatory Bowel Diseases, Medication Adherence, Checklist
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