The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Treatment Adherence in Adolescents With Inflammatory Bowel Disease: The Collective Impact of Barriers to Adherence and Anxiety/Depressive Symptoms
Open accessAbstract
OBJECTIVE: Knowledge of factors impacting adolescents' ability to adhere to their inflammatory bowel disease (IBD) regimen is limited. The current study examines the collective impact of barriers to adherence and anxiety/depressive symptoms on adolescent adherence to the IBD regimen. METHODS: Adolescents (n = 79) completed measures of barriers to adherence, adherence, and anxiety/depressive symptoms at one of two specialty pediatric IBD clinics. RESULTS: Most adolescents reported barriers to adherence and 1 in 8 reported borderline or clinically elevated levels of anxiety/depressive symptoms. Anxiety/depressive symptoms moderated the relationship between barriers to adherence and adherence. Post hoc probing revealed a significant, additive effect of higher anxiety/depressive symptoms in the barriers-adherence relationship, with adherence significantly lower among adolescents with higher barriers and higher anxiety/depressive symptoms. CONCLUSIONS: In order to optimize adherence in adolescents, interventions should target not only barriers to adherence but also any anxiety/depressive symptoms that may negatively impact efforts to adhere to recommended treatment.
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“Indeed, comorbid psychological difficulties are associated with disease activity, flares, treatment response, and the necessity of surgical intervention [2,6,8,9,10,11,12,13,14,15].”
From Brief and Telehealth Acceptance and Commitment Therapy (ACT) Interventions for Stress in Inflammatory Bowel Disease (IBD): A Series of Single Case Experimental Design (SCED) Studies (2022) · cites this paper as [11]
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Lamb, C. A., Kennedy, N. A., Raine, T., Hendy, P. A., Smith, P. J., Limdi, J. K., Hayee, B., Lomer, M. C. E., Parkes, G. C., Selinger, C., et al. (2019) · Gut · doi:10.1136/gutjnl-2019-318484 · Cited by 2,346
Increased burden of psychiatric disorders in inflammatory bowel disease
Bernstein, C. N., Hitchon, C. A., Walld, R., Bolton, J. M., Sareen, J., Walker, J. R., Graff, L. A., Patten, S. B., Singer, A., Lix, L. M., et al. (2019) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izy235 · Cited by 274
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Etiology and Treatment of Pain and Psychosocial Issues in Patients With Inflammatory Bowel Diseases
Regueiro, M., Greer, J. B., & Szigethy, E. (2017) · Gastroenterology · doi:10.1053/j.gastro.2016.10.036 · Cited by 142
Metadata
- Authors
- Gray, W. N., Denson, L. A., Baldassano, R. N., & Hommel, K. A.
- Affiliations
- Cincinnati Children's Hospital Medical Center (US)
- Venue
- Journal of Pediatric Psychology
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-11-10
- Volume
- 37
- Issue
- 3
- Pages
- 282-291
- ISSN
- 0146-8693 (ISSN-L)
- 1465-735X
- PMC
- PMC3306169
- OpenAlex
- W2142245641
- Cited by
- 143
- References
- 53
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 7 · 2023: 16 · 2022: 9 · 2021: 14 · 2020: 12 · 2019: 9 · 2018: 11 · 2017: 13 · 2016: 10 · 2015: 10 · 2014: 10 · 2013: 13 · 2012: 3
- FWCI
- 7.65
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Pediatric Psychology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Procter and Gamble
- National Institutes of Health (5ul1rr026314-03, UL1TR000077, 1UL1RR026314)
- National Institute of Diabetes and Digestive and Kidney Diseases (K23DK079037)
- National Center for Research Resources (1UL1RR026314, UL1-RR026314)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Adolescent and Pediatric Healthcare
- Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
- Keywords
- inflammatory bowel disease, adolescents, medication adherence, barriers to adherence, anxiety symptoms, depressive symptoms, psychosocial factors, pediatric inflammatory bowel disease
- MeSH terms
- Adolescent, Adolescent Behavior, Anxiety, Colitis, Ulcerative, Crohn Disease, Depression, Female, Humans, Male, Severity of Illness Index, Inflammatory Bowel Diseases, Medication Adherence, Checklist
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