The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
The Expansion of mtDNA Haplogroup L3 within and out of Africa
Abstract
Although fossil remains show that anatomically modern humans dispersed out of Africa into the Near East ∼100 to 130 ka, genetic evidence from extant populations has suggested that non-Africans descend primarily from a single successful later migration. Within the human mitochondrial DNA (mtDNA) tree, haplogroup L3 encompasses not only many sub-Saharan Africans but also all ancient non-African lineages, and its age therefore provides an upper bound for the dispersal out of Africa. An analysis of 369 complete African L3 sequences places this maximum at ∼70 ka, virtually ruling out a successful exit before 74 ka, the date of the Toba volcanic supereruption in Sumatra. The similarity of the age of L3 to its two non-African daughter haplogroups, M and N, suggests that the same process was likely responsible for both the L3 expansion in Eastern Africa and the dispersal of a small group of modern humans out of Africa to settle the rest of the world. The timing of the expansion of L3 suggests a link to improved climatic conditions after ∼70 ka in Eastern and Central Africa rather than to symbolically mediated behavior, which evidently arose considerably earlier. The L3 mtDNA pool within Africa suggests a migration from Eastern Africa to Central Africa ∼60 to 35 ka and major migrations in the immediate postglacial again linked to climate. The largest population size increase seen in the L3 data is 3-4 ka in Central Africa, corresponding to Bantu expansions, leading diverse L3 lineages to spread into Eastern and Southern Africa in the last 3-2 ka.
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Cites
Relaxed Phylogenetics and Dating with Confidence
Drummond, A. J., Ho, S. Y. W., Phillips, M. J., & Rambaut, A. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040088 · Cited by 6,463
Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA
Andrews, R. M., Kubacka, I., Chinnery, P. F., Lightowlers, R. N., Turnbull, D. M., & Howell, N. (1999) · Nature Genetics · doi:10.1038/13779 · Cited by 3,337
Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation
van Oven, M., & Kayser, M. (2009) · Human Mutation · doi:10.1002/humu.20921 · Cited by 1,810
The Genetic Structure and History of Africans and African Americans
Tishkoff, S. A., Reed, F. A., Friedlaender, F. R., Ehret, C., Ranciaro, A., Froment, A., Hirbo, J. B., Awomoyi, A. A., Bodo, J.-M., Doumbo, O., et al. (2009) · Science · doi:10.1126/science.1172257 · Cited by 1,573
Additional evidence on the use of personal ornaments in the Middle Paleolithic of North Africa
d'Errico, F., Vanhaeren, M., Barton, N., Bouzouggar, A., Mienis, H., Richter, D., Hublin, J.-J., McPherron, S. P., & Lozouet, P. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903532106 · Cited by 379
U-series and ESR analyses of bones and teeth relating to the human burials from Skhul
Grün, R., Stringer, C., McDermott, F., Nathan, R., Porat, N., Robertson, S., Taylor, L., Mortimer, G., Eggins, S., & McCulloch, M. (2005) · Journal of Human Evolution · doi:10.1016/j.jhevol.2005.04.006 · Cited by 338
Rapid, global demographic expansions after the origins of agriculture
Gignoux, C. R., Henn, B. M., & Mountain, J. L. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914274108 · Cited by 267
Getting “Out of Africa”: Sea Crossings, Land Crossings and Culture in the Hominin Migrations
Derricourt, R. (2005) · Journal of World Prehistory · doi:10.1007/s10963-006-9002-z · Cited by 172
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Scally, A., & Durbin, R. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3295 · Cited by 610
Southern African ancient genomes estimate modern human divergence to 350,000 to 260,000 years ago
Schlebusch, C. M., Malmström, H., Günther, T., Sjödin, P., Coutinho, A., Edlund, H., Munters, A. R., Vicente, M., Steyn, M., Soodyall, H., et al. (2017) · Science · doi:10.1126/science.aao6266 · Cited by 519
Late Pleistocene climate drivers of early human migration
Timmermann, A., & Friedrich, T. (2016) · Nature · doi:10.1038/nature19365 · Cited by 328
Rethinking the dispersal of Homo sapiens out of Africa
Groucutt, H. S., Petraglia, M. D., Bailey, G., Scerri, E. M. L., Parton, A., Clark‐Balzan, L., Jennings, R. P., Lewis, L., Blinkhorn, J., Drake, N. A., et al. (2015) · Evolutionary Anthropology: Issues, News, and Reviews · doi:10.1002/evan.21455 · Cited by 317
Genetic and archaeological perspectives on the initial modern human colonization of southern Asia
Mellars, P., Gori, K. C., Carr, M., Soares, P. A., & Richards, M. B. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1306043110 · Cited by 276
Self-citation
Metadata
- Authors
- Soares, P., Alshamali, F., Pereira, J. B., Fernandes, V., Silva, N. M., Afonso, C., Costa, M. D., Musilova, E., Macaulay, V., Richards, M. B., Cerny, V., & Pereira, L.
- Venue
- Molecular Biology and Evolution
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-11-16
- Volume
- 29
- Issue
- 3
- Pages
- 915-927
- ISSN
- 0737-4038 (ISSN-L)
- 1537-1719
- OpenAlex
- W2157554345
- Cited by
- 253
- References
- 8
- FWCI
- 7.13
- Type
- journal article
- Language
- en
- Open access
- closed
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