Cited by 228Endometriosis Research and TreatmentReproductive System and PregnancyGynecological conditions and treatments

The DOI matches its Crossref record; 69 of the 71 references it cites were found in a registry or an index.

Altered expression of HOXA10 in endometriosis: potential role in decidualization

Kim, J.Julie, Taylor, H.S., Lu, Z., Ladhani, O., Hastings, J.M., Jackson, K.S., Wu, Y., Guo, S.W., Fazleabas, A.T.·2007·MHR: Basic science of reproductive medicine

DOI 10.1093/molehr/gam005

Open this paper in CoChat — free account

Abstract

Endometriosis is a poorly understood gynaecologic disorder that is associated with infertility. In this study, we examined the expression of HOXA10 in the eutopic endometrium of baboons with induced endometriosis. A decrease in HOXA10 mRNA was observed after 3, 6, 12 and 16 months of disease, which reached statistical significance at 12 and 16 months. HOXA10 protein levels were decreased in both the epithelial and stromal cells of the endometrium. Furthermore, expression of beta3 integrin (ITGB3), which is upregulated by HOXA10, was decreased, whereas EMX2, a gene that is inhibited by HOXA10, was increased. Next, methylation patterns of the HOXA10 gene were analysed in the diseased and control animals. The F1 region on the promoter was found to be the most significantly methylated in the endometriosis animals and this may account for the decrease in HOXA10 expression. Finally, we demonstrate that stromal cells from the eutopic endometrium of baboons with endometriosis expressed significantly higher levels of insulin-like growth factor binding protein-1 (IGFBP1) mRNA than disease-free animals in response to estradiol, medroxyprogesterone acetate and dibutyryl cAMP (H + dbcAMP). The functional role of HOXA10 in IGFBP1 expression was further explored using human endometrial stromal cells (HSC). Overexpression of HOXA10 in HSC resulted in a decrease of IGFBP1 mRNA, whereas silencing HOXA10 caused an increase of IGFBP1 mRNA, even in the presence of H + dbcAMP. These data demonstrate that HOXA10 negatively influences IGFBP1 expression in decidualizing cells. Thus, the decrease in HOXA10 levels may in part be involved with the altered uterine environment associated with endometriosis.

Integrity signals

Registry

Crossref · 10.1093/molehr/gam005

Cites

69 of 69 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
Livak, K. J., & Schmittgen, T. D. (2001) · Methods · doi:10.1006/meth.2001.1262 · Cited by 180,860
Insulin-Like Growth Factors and Their Binding Proteins: Biological Actions*
Jones, J. I. W., & Clemmons, D. R. (1995) · Endocrine Reviews · doi:10.1210/edrv-16-1-3 · Cited by 4,488
A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands
Frommer, M., McDonald, L. E., Millar, D. S., Collis, C. M., Watt, F., Grigg, G. W., Molloy, P. L., & Paul, C. L. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.5.1827 · Cited by 3,238
EPIDEMIOLOGY OF ENDOMETRIOSIS
Eskenazi, B., & Warner, M. L. (1997) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/s0889-8545(05)70302-8 · Cited by 1,617
Effect of endometriosis on in vitro fertilization
Barnhart, K. T., Dunsmoor-Su, R. F., & Coutifaris, C. (2002) · Fertility and Sterility · doi:10.1016/s0015-0282(02)03112-6 · Cited by 805
Subgroup of reproductive functions of progesterone mediated by progesterone receptor-B isoform
Mulac-Jericevic, B., Mullinax, R. A., DeMayo, F. J., Lydon, J. P., & Conneely, O. M. (2000) · Science · doi:10.1126/science.289.5485.1751 · Cited by 704
Expression Profiling of Endometrium from Women with Endometriosis Reveals Candidate Genes for Disease-Based Implantation Failure and Infertility
Kao, L. C., Germeyer, A., Tulac, S., Lobo, S., Yang, J. P., Taylor, R. N., Osteen, K., Lessey, B. A., & Giudice, L. C. (2003) · Endocrinology · doi:10.1210/en.2003-0043 · Cited by 696
Accelerated age-related CpG island methylation in ulcerative colitis.
Issa, J. J., Ahuja, N., Toyota, M., Bronner, M. P., & Brentnall, T. A. (2001) · PubMed · Cited by 627
HOXA10 is expressed in response to sex steroids at the time of implantation in the human endometrium.
Taylor, H. S., Arici, A. M., Olive, D. L., & Igarashi, P. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1057 · Cited by 555
Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence.
Jones, J. I., Gockerman, A., Busby, W. H., Wright, G., & Clemmons, D. R. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.22.10553 · Cited by 515
Aberrant integrin expression in the endometrium of women with endometriosis
Lessey, B. A., Castelbaum, A. J., Sawin, S. W., Buck, C. A., Schinnar, R., Bilker, W. B., & Strom, B. L. (1994) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.79.2.7519194 · Cited by 514
Mechanisms of reduced fertility in Hoxa-10 mutant mice: uterine homeosis and loss of maternal Hoxa-10 expression
Benson, G. V., Lim, H. J., Paria, B. C., Satokata, I., Dey, S. K., & Maas, R. L. (1996) · Development · doi:10.1242/dev.122.9.2687 · Cited by 501
Studies on the surgical induction of endometriosis in the rat.
Vernon, M. W., & Wilson, E. A. (1985) · Fertility and Sterility · doi:10.1016/s0015-0282(16)48988-0 · Cited by 482
HOXA10 is expressed in response to sex steroids at the time of implantation in the human endometrium.
Taylor, H. S., Arici, A. M., Olive, D. L., & Igarashi, P. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1597 · Cited by 420
HOX gene expression is altered in the endometrium of women with endometriosis
Taylor, H. S. (1999) · Human Reproduction · doi:10.1093/humrep/14.5.1328 · Cited by 376
Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis
Sallam, H. N., Garcia-Velasco, J. A., Dias, S., Arici, A., Abou-Setta, A. M., & Jaafar, S. H. (2006) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004635.pub2 · Cited by 349
Progesterone Regulates Transcription of the p21 Cyclindependent Kinase Inhibitor Gene through Sp1 and CBP/p300
Owen, G. I., Richer, J. K., Tung, L. W., Takimoto, G. S., & Horwitz, K. B. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.17.10696 · Cited by 348
Aberrant methylation at HOXA10 may be responsible for its aberrant expression in the endometrium of patients with endometriosis
Wu, Y., Halverson, G., Basir, Z., Strawn, E., Yan, P., & Guo, S.-W. (2005) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2005.01.034 · Cited by 283
Self-citation
Suppression of matrix metalloproteinases inhibits establishment of ectopic lesions by human endometrium in nude mice.
Bruner‐Tran, K. L., Matrisian, L. M., Rodgers, W. H., Gorstein, F., & Osteen, K. G. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119478 · Cited by 283
Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity
Klemmt, P. A. B., Carver, J. G., Kennedy, S., Koninckx, P. R., & Mardon, H. J. (2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2005.08.046 · Cited by 256
Hypermethylation of the p16INK4a promoter in colectomy specimens of patients with long-standing and extensive ulcerative colitis.
Hsieh, C. ‐., Klump, B., Holzmann, K., Borchard, F., Gregor, M., & Porschen, R. (1998) · PubMed · Cited by 241
Regulation of HOXA-10 Expression by Testosterone in Vitro and in the Endometrium of Patients with Polycystic Ovary Syndrome
Cermik, D., Selam, B., & Taylor, H. S. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021072 · Cited by 220
Alteration of maternal Hoxa10 expression by in vivo gene transfection affects implantation
Bagot, C. N., Troy, P. J., & Taylor, H. S. (2000) · Gene Therapy · doi:10.1038/sj.gt.3301245 · Cited by 220
The effect of endometriosis on implantation: results from the Yale University in vitro fertilization and embryo transfer program
Arici, A. M., Oral, E., Bükülmez, O., Dulęba, A. J., Olive, D. L., & Jones, E. E. (1996) · Fertility and Sterility · doi:10.1016/s0015-0282(16)58162-x · Cited by 219
Animal models in endometriosis research
Grümmer, R. (2006) · Human Reproduction Update · doi:10.1093/humupd/dml026 · Cited by 216
Exploring the mechanism(s) of endometriosis-related infertility: an analysis of embryo development and implantation in assisted reproduction
Pellicer, A., Oliveira, N., Ruiz, A., Remohi, J., & Simón, C. (1995) · Human Reproduction · doi:10.1093/humrep/10.suppl_2.91 · Cited by 202
Progesterone Receptor Isoform A But Not B Is Expressed in Endometriosis1
Attia, G. R., Zeitoun, K., Edwards, D., Johns, A., Carr, B. R., & Bulun, S. E. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.8.6739 · Cited by 193
Aging, DNA methylation and cancer
Issa, J. J. (1999) · Critical Reviews in Oncology/Hematology · doi:10.1016/s1040-8428(99)00019-0 · Cited by 185
Intrapelvic injection of menstrual endometrium causes endometriosis in baboons (Papio cynocephalus and Papio anubis)
D’Hooghe, T. M., Bambra, C. S., Raeymaekers, B. M., Jonge, I. D., Lauweryns, J. M., & Koninckx, P. R. (1995) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(95)90180-9 · Cited by 182
Convergence of Progesterone with Growth Factor and Cytokine Signaling in Breast Cancer
Richer, J. K., Lange, C. A., Manning, N. G., Owen, G. I., Powell, R. L., & Horwitz, K. B. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.47.31317 · Cited by 181
Interleukin-11, IL-11 receptorα and leukemia inhibitory factor are dysregulated in endometrium of infertile women with endometriosis during the implantation window
Dimitriadis, E., Stoikos, C. J., Stafford‐Bell, M. A., Clark, I., Paiva, P., Kovács, G., & Salamonsen, L. A. (2005) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2005.07.004 · Cited by 178
Cyclic AMP-induced Forkhead Transcription Factor, FKHR, Cooperates with CCAAT/Enhancer-binding Protein β in Differentiating Human Endometrial Stromal Cells
Christian, M., Zhang, X., Schneider‐Merck, T., Unterman, T. G., Gellersen, B., WHITE, J. O., & Brosens, J. J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m201018200 · Cited by 177
Direct Regulation of 3-Integrin Subunit Gene Expression by HOXA10 in Endometrial Cells
Daftary, G. S., Troy, P. J., Bagot, C. N., Young, S. L., & Taylor, H. S. (2002) · Molecular Endocrinology · doi:10.1210/mend.16.3.0792 · Cited by 176
Role of laparoscopic treatment of endometriosis in patients with failed in vitro fertilization cycles
Littman, E. D., Giudice, L. C., Lathi, R. B., Berker, B., Milki, A. A., & NEZHAT, C. R. (2005) · Fertility and Sterility · doi:10.1016/j.fertnstert.2005.02.059 · Cited by 162
Modulation of the baboon ( Papio anubis ) uterine endometrium by chorionic gonadotrophin during the period of uterine receptivity
Fazleabas, A. T., Donnelly, K. M., Srinivasan, S., Fortman, J. D., & Miller, J. B. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.5.2543 · Cited by 156
Death or survival – progesterone-dependent cell fate decisions in the human endometrial stroma
Brosens, J. J., & Gellersen, B. (2006) · Journal of Molecular Endocrinology · doi:10.1677/jme.1.02060 · Cited by 146
Regulation of HOXA-10 and its expression in normal and abnormal endometrium
Gui, Y., Zhang, J., Yuan, L., & Lessey, B. A. (1999) · MHR: Basic science of reproductive medicine · doi:10.1093/molehr/5.9.866 · Cited by 139
Clinical relevance of the baboon as a model for the study of endometriosis
D’Hooghe, T. M. (1997) · Fertility and Sterility · doi:10.1016/s0015-0282(97)00277-x · Cited by 137
Surgical Induction of Endometriosis in the Rabbit: Effects on Fertility and Concentrations of Peritoneal Fluid Prostaglandins
Schenken, R. S., & Asch, R. H. (1980) · Fertility and Sterility · doi:10.1016/s0015-0282(16)45199-x · Cited by 134
Transcriptional Repression of Peri-Implantation EMX2 Expression in Mammalian Reproduction by HOXA10
Troy, P. J., Daftary, G. S., Bagot, C. N., & Taylor, H. S. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.23.1.1-13.2003 · Cited by 132
p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cellsPreprint
Bromleigh, V. C., & Freedman, L. P. (2000) · Genes & Development · doi:10.1101/gad.817100 · Cited by 129
A Modified Baboon Model for Endometriosis
Fazleabas, A. T., Brudney, A., Gürateş, B., Chai, D. C., & Bulun, S. E. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb02791.x · Cited by 120
Activin A Promotes Human Endometrial Stromal Cell Decidualizationin Vitro
Jones, R. L., Salamonsen, L. A., & Findlay, J. K. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.8.8880 · Cited by 118
Steroid receptor and aromatase expression in baboon endometriotic lesions
Fazleabas, A. T., Brudney, A., Chai, D. C., Langoi, D., & Bulun, S. E. (2003) · Fertility and Sterility · doi:10.1016/s0015-0282(03)00982-8 · Cited by 111
Regulation of Insulin-Like Growth Factor Binding Protein-1 Promoter Activity by FKHR and HOXA10 in Primate Endometrial Cells1
Kim, J. J., Taylor, H. S., Akbas, G. E., Foucher, I., Trembleau, A., Jaffe, R. C., Fazleabas, A. T., & Unterman, T. G. (2003) · Biology of Reproduction · doi:10.1095/biolreprod.102.009316 · Cited by 106
Role of FOXO1A in the Regulation of Insulin-Like Growth Factor-Binding Protein-1 in Human Endometrial Cells: Interaction with Progesterone Receptor1
Kim, J. J., Buzzio, O. L., Li, S., & Lu, Z. (2005) · Biology of Reproduction · doi:10.1095/biolreprod.105.043182 · Cited by 98
HOXA10, Pbx2, and Meis1 Protein Expression in the Human Endometrium: Formation of Multimeric Complexes on HOXA10 Target Genes
Sarno, J. L., Kliman, H. J., & Taylor, H. S. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0817 · Cited by 98
Transplantation of normal and ectopic human endometrial tissue into athymic nude mice
Zamah, N. M., Dodson, M. G., Stephens, L. C., Buttram, V. C., Besch, P. K., & Kaufman, R. H. (1984) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(84)90240-0 · Cited by 97
Proteomic analysis identifies immunophilin FK506 binding protein 4 (FKBP52) as a downstream target of Hoxa10 in the periimplantation mouse uterus.
Daikoku, T., Tranguch, S., Friedman, D., Das, S., Smith, D. F., & Dey, S. (2005) · Molecular Endocrinology · doi:10.1210/me.2004-0332 · Cited by 90
Tyrosine Phosphorylation of HoxA10 Decreases DNA Binding and Transcriptional Repression during Interferon γ-induced Differentiation of Myeloid Leukemia Cell Lines
Eklund, E. A., Jalava, A., & Kakar, R. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m907915199 · Cited by 85
Activation of Stem‐Cell Specific Genes by HOXA9 and HOXA10 Homeodomain Proteins in CD34+Human Cord Blood Cells
Ferrell, C. M., Dorsam, S. T., Ohta, H., Humphries, R. K., Derynck, M. K., Haqq, C., Largman, C., & Lawrence, H. J. (2005) · Stem Cells · doi:10.1634/stemcells.2004-0198 · Cited by 84
Induced Endometriosis in the Baboon (Papio anubis) Increases the Expression of the Proangiogenic Factor CYR61 (CCN1) in Eutopic and Ectopic Endometria1
Gashaw, I., Hastings, J. M., Jackson, K. S., Winterhager, E., & Fazleabas, A. T. (2006) · Biology of Reproduction · doi:10.1095/biolreprod.105.049320 · Cited by 81
Regulation of Aromatase P450 Expression in Endometriotic and Endometrial Stromal Cells by CCAAT/Enhancer Binding Proteins (C/EBPs): Decreased C/EBPβ in Endometriosis Is Associated with Overexpression of Aromatase
Yang, S., Fang, Z., Suzuki, T., Sasano, H., Zhou, J., Gurates, B., Tamura, M., Ferrer, K., & Bulun, S. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.5.8486 · Cited by 77
EMX2 Gene Expression in the Female Reproductive Tract and Aberrant Expression in the Endometrium of Patients with Endometriosis
Daftary, G. S., & Taylor, H. S. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031389 · Cited by 67
Eutopic endometrium and peritoneal, ovarian and bowel endometriotic tissues express a different profile of matrix metalloproteinases-2, -3 and -11, and of tissue inhibitor metalloproteinases-1 and -2
Uzan, C., Cortez, A., Dufournet, C., Fauvet, R., Siffroi, J., & Daraï, É. (2004) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-004-1117-y · Cited by 65
Increased secretion of hepatocyte growth factor by eutopic endometrial stromal cells in women with endometriosis
Sugawara, J., Fukaya, T., Murakami, T., Yoshida, H., & Yajima, A. (1997) · Fertility and Sterility · doi:10.1016/s0015-0282(97)00226-4 · Cited by 64
Dysregulated Expression ofebaf, a Novel Molecular Defect in the Endometria of Patients with Infertility1
TABIBZADEH, S. S., Mason, J. M., Shea, W., Cai, Y., Murray, M. J., & Lessey, B. A. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.7.6674 · Cited by 63
An Insulin-Like Growth Factor-Binding Protein in the Baboon (Papio anubis) Endometrium: Synthesis, Immunocytochemical Localization, and Hormonal Regulation*
Fazleabas, A. T., Jaffe, R. C., Verhage, H. G., WAITES, G. T., & Bell, S. C. (1989) · Endocrinology · doi:10.1210/endo-124-5-2321 · Cited by 62
The Estrogen Early Response Gene FOS Is Altered in a Baboon Model of Endometriosis1
Hastings, J. M., Jackson, K. S., Mavrogianis, P. A., & Fazleabas, A. T. (2006) · Biology of Reproduction · doi:10.1095/biolreprod.106.052852 · Cited by 55
HOXA10 expression in ectopic endometrial tissue
Browne, H. N., & Taylor, H. S. (2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2005.10.072 · Cited by 54
Dysregulated Expression of ebaf, a Novel Molecular Defect in the Endometria of Patients with Infertility
TABIBZADEH, S. S. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.85.7.2526 · Cited by 53
A Baboon Model for Inducing Endometriosis
Fazleabas, A. T. (2005) · Humana Press eBooks · doi:10.1385/1-59259-983-4:093 · Cited by 47
HoxA10 Represses Gene Transcription in Undifferentiated Myeloid Cells by Interaction with Histone Deacetylase 2
Lu, Y., Goldenberg, I., Bei, L., Andrejic, J., & Eklund, E. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305885200 · Cited by 43
Blastocyst invasion and the stromal response in primates
Kim, J., Jaffe, R. C., & Fazleabas, A. T. (1999) · Human Reproduction · doi:10.1093/humrep/14.suppl_2.45 · Cited by 36
Activin‐A secretion is increased in the eutopic endometrium from women with essndometriosis
ROMBAUTS, L., DONOGHUE, J., CANN, L., JONES, R. L., & HEALY, D. L. (2006) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/j.1479-828x.2006.00546.x · Cited by 35
Hox Proteins Activate the IGFBP-1 Promoter and Suppress the Function of hPR in Human Endometrial Cells
Gao, J., Mazella, J., & Tseng, L. (2002) · DNA and Cell Biology · doi:10.1089/104454902320908469 · Cited by 32
HOXA10 gene expression in human fallopian tube and ectopic pregnancy
Salih, S. M., & Taylor, H. S. (2004) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2004.01.066 · Cited by 31
Morphological and glycosylation changes associated with the endometrium and ectopic lesions in a baboon model of endometriosis
Jones, C., Denton, J., & Fazleabas, A. T. (2006) · Human Reproduction · doi:10.1093/humrep/del310 · Cited by 26
Transforming the Hox code
Krumlauf, R. K. (1992) · Current Biology · doi:10.1016/0960-9822(92)90107-l · Cited by 6

Sorted by citations

Endometriosis is a chronic systemic disease: Clinical challenges and novel innovations
Taylor, H. S., Kotlyar, A. M., & Flores, V. A. (2021) · The Lancet · doi:10.1016/s0140-6736(21)00389-5 · Cited by 1,425
Endometriosis and Infertility
Macer, M. L., & Taylor, H. S. (2012) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/j.ogc.2012.10.002 · Cited by 681
Decidualization of the Human Endometrium: Mechanisms, Functions, and Clinical Perspectives
Gellersen, B., Brosens, I., & Brosens, J. J. (2007) · Seminars in Reproductive Medicine · doi:10.1055/s-2007-991042 · Cited by 587
Progesterone and Estrogen Signaling in the Endometrium: What Goes Wrong in Endometriosis?
Marquardt, R. M., Kim, T. H., Shin, J., & Jeong, J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20153822 · Cited by 527
Implantation failure: molecular mechanisms and clinical treatment
Çakmak, H., & Taylor, H. S. (2010) · Human Reproduction Update · doi:10.1093/humupd/dmq037 · Cited by 396

See all 228

Authors: Kim, J. J., Taylor, H. S., Lu, Z., Ladhani, O., Hastings, J. M., Jackson, K. S., Wu, Y., Guo, S. W., & Fazleabas, A. T.
Affiliations: Northwestern University (US)
Yale University (US)
University of Illinois Chicago (US)
Medical College of Wisconsin (US)
Corresponding author: Kim, J.Julie
ORCID: Kim, J.Julie
Taylor, H.S.
Hastings, J.M.
Jackson, K.S.
Wu, Y.
Guo, S.W.
Fazleabas, A.T.
Venue: MHR: Basic science of reproductive medicine
Publisher: Oxford University Press (OUP)
Published: 2007-03-09
Volume: 13
Issue: 5
Pages: 323-332
ISSN: 1360-9947 (ISSN-L)
1460-2407
DOI: 10.1093/molehr/gam005
OpenAlex: W2137799669
Cited by: 228
References: 71
Citations by year: 2026: 4 · 2025: 5 · 2024: 6 · 2023: 9 · 2022: 9 · 2021: 13 · 2020: 2 · 2019: 8 · 2018: 15 · 2017: 11 · 2016: 19 · 2015: 11 · 2014: 13 · 2013: 11 · 2012: 17
FWCI: 20.63
Type: journal article
Language: en
Open access: closed
Locations: Molecular Human Reproduction (publishedVersion)
PubMed (publishedVersion)
Funders: Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD-036887, U54HD040093, U54-HD40093, R01HD044715, HD 044715)
Topics: Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
Keywords: endometriosis, HOXA10, decidualization, eutopic endometrium, IGFBP-1, CD61, Emx2, DNA methylation, promoter methylation, endometrial stromal cells, baboon model, infertility, estradiol, medroxyprogesterone acetate, cyclic AMP
MeSH terms: Homeobox A10 Proteins, Empty Spiracles Homeobox Proteins, Animals, Cells, Cultured, Decidua, Bucladesine, Endometriosis, Endometrium, Epithelial Cells, Estradiol, Female, Gene Expression Regulation, Humans, Papio, Promoter Regions, Genetic, RNA, Messenger, Transcription Factors, Stromal Cells, Medroxyprogesterone Acetate, Homeodomain Proteins, Insulin-Like Growth Factor Binding Protein 1, DNA Methylation, Gene Silencing

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Altered expression of HOXA10 in endometriosis: potential role in decidualization

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks