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Co-occupancy of two Pumilio molecules on a single hunchback NRE

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Function of alternative splicing

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Exposing synonymous mutations

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Comprehensive identification of internal structure and alternative splicing events in circular RNAs

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RNA Helicases DDX5 and DDX17 Dynamically Orchestrate Transcription, miRNA, and Splicing Programs in Cell Differentiation

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Racial, ethnic and socioeconomic disparities in the clustering of cardiovascular disease risk factors.

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SpliceAid-F: a database of human splicing factors and their RNA-binding sites

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Drift and conservation of differential exon usage across tissues in primate species

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Exon-centric regulation of pyruvate kinase M alternative splicing via mutually exclusive exons

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A High-Resolution Map of Human Enhancer RNA Loci Characterizes Super-enhancer Activities in Cancer

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A novel methyltransferase from the intracellular pathogen P lasmodiophora brassicae methylates salicylic acid

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RNA splicing in human disease and in the clinic

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Rules and tools to predict the splicing effects of exonic and intronic mutations

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DAZL Limits Pluripotency, Differentiation, and Apoptosis in Developing Primordial Germ Cells

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Genome-Wide Identification of Fas/CD95 Alternative Splicing Regulators Reveals Links with Iron Homeostasis

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Alternative Splicing of SLC39A14 in Colorectal Cancer is Regulated by the Wnt Pathway

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SRSF5 functions as a novel oncogenic splicing factor and is upregulated by oncogene SRSF3 in oral squamous cell carcinoma

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Splicing of long non-coding RNAs primarily depends on polypyrimidine tract and 5′ splice-site sequences due to weak interactions with SR proteins

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Oncogenic splicing factor SRSF3 regulates ILF3 alternative splicing to promote cancer cell proliferation and transformation

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Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors

Duarte-Pereira, S., Pereira‐Castro, I., Silva, S. S., Correia, M. G., Neto, C., da Costa, L. T., Amorim, A., & Silva, R. M. (2015) · Oncotarget · doi:10.18632/oncotarget.6538 · Cited by 68 · see citing works

Biophysical characterization of G-quadruplex forming FMR1 mRNA and of its interactions with different fragile X mental retardation protein isoforms

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RNAmotifs: prediction of multivalent RNA motifs that control alternative splicing

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Cosplicing network analysis of mammalian brain RNA-Seq data utilizing WGCNA and Mantel correlations

Iancu, O. D., Colville, A., Oberbeck, D., Darakjian, P., McWeeney, S. K., & Hitzemann, R. (2015) · Frontiers in Genetics · doi:10.3389/fgene.2015.00174 · Cited by 57 · see citing works

How motif environment influences transcription factor search dynamics: Finding a needle in a haystack

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A novel L1CAM isoform with angiogenic activity generated by NOVA2-mediated alternative splicing

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SpliceDisease database: linking RNA splicing and disease

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A Requirement for Mena, an Actin Regulator, in Local mRNA Translation in Developing Neurons

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Serine/Arginine-Rich Splicing Factor 3 and Heterogeneous Nuclear Ribonucleoprotein A1 Regulate Alternative RNA Splicing and Gene Expression of Human Papillomavirus 18 through Two Functionally Distinguishable cis Elements

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Oral squamous cancer cell exploits hnRNP A1 to regulate cell cycle and proliferation

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Global Promotion of Alternative Internal Exon Usage by mRNA 3′ End Formation Factors

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The neuronal splicing factor Nova controls alternative splicing in N-type and P-type Ca_V2 calcium channels

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Alteration of splicing factors’ expression during liver disease progression: impact on hepatocellular carcinoma outcome

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CD5 expression is regulated during human T‐cell activation by alternative polyadenylation, PTBP1, and miR‐204

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Exon-skipping antisense oligonucleotides for cystic fibrosis therapy

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GFAP splice variants fine-tune glioma cell invasion and tumour dynamics by modulating migration persistence

Uceda-Castro, R., van Asperen, J. V., Vennin, C., Sluijs, J. A., van Bodegraven, E. J., Margarido, A. S., Robe, P. A. J. T., van Rheenen, J., & Hol, E. M. (2022) · Scientific Reports · doi:10.1038/s41598-021-04127-5 · Cited by 44 · see citing works

The hnRNP F/H homologue of Trypanosoma brucei is differentially expressed in the two life cycle stages of the parasite and regulates splicing and mRNA stability

Gupta, S. K., Kosti, I., Plaut, G., Pivko, A., Tkacz, I. D., Cohen‐Chalamish, S., Biswas, D. K., Wachtel, C., Ben‐Asher, H. W., Carmi, S., et al. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt369 · Cited by 42 · see citing works

Genomic structure and expression of the human serotonin 2A receptor gene (HTR2A) locus: identification of novel HTR2A and antisense (HTR2A-AS1) exons

Ruble, C., Smith, R. M., Calley, J. N., Munsie, L. M., Airey, D. C., Gao, Y., Shin, J. H., Hyde, T. M., Straub, R. E., Weinberger, D. R., et al. (2016) · BMC Genetics · doi:10.1186/s12863-015-0325-6 · Cited by 41 · see citing works

BRCA1 exon 11 a model of long exon splicing regulation

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Regulation of Numb isoform expression by activated ERK signaling

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How might ZNF804A variants influence risk for schizophrenia and bipolar disorder? A literature review, synthesis, and bioinformatic analysis

Hess, J., & Glatt, S. J. (2013) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32207 · Cited by 33 · see citing works

RBPmap: A Tool for Mapping and Predicting the Binding Sites of RNA-Binding Proteins Considering the Motif Environment

Paz, I., Argoetti, A., Cohen, N., Even, N., & Mandel‐Gutfreund, Y. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1851-6_3 · Cited by 34 · see citing works

Identification of cis-Acting Elements and Splicing Factors Involved in the Regulation of BIM Pre-mRNA Splicing

Juan, W. C., Roca, X., & Ong, S. T. (2014) · PLoS ONE · doi:10.1371/journal.pone.0095210 · Cited by 34 · see citing works

Characterization of the Regulation of CD46 RNA Alternative Splicing

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Computational analysis reveals a correlation of exon-skipping events with splicing, transcription and epigenetic factors

Ye, Z., Chen, Z., Lan, X., Hara, S., Sunkel, B. D., Huang, T. H. ‐., Elnitski, L. L., Wang, Q., & Jin, V. X. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt1338 · Cited by 31 · see citing works

Splicing regulation and dysregulation of cholinergic genes expressed at the neuromuscular junction

Ohno, K., Rahman, M. A., Nazim, M., Nasrin, F., Lin, Y., Takeda, J., & Masuda, A. (2017) · Journal of Neurochemistry · doi:10.1111/jnc.13954 · Cited by 27 · see citing works

Both maintenance and avoidance of RNA-binding protein interactions constrain coding sequence evolution

Savisaar, R., & Hurst, L. D. (2017) · Molecular Biology and Evolution · doi:10.1093/molbev/msx061 · Cited by 26 · see citing works

A TLR/CD44 axis regulates T cell trafficking in experimental and human multiple sclerosis

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Muscleblind-Like 1 and Muscleblind-Like 3 Depletion Synergistically Enhances Myotonia by Altering Clc-1 RNA Translation

Choi, J., Personius, K. E., DiFranco, M., Dansithong, W., Yu, C., Srivastava, S., Dixon, D. M., Bhatt, D. B., Comai, L., Vergara, J. L., et al. (2015) · EBioMedicine · doi:10.1016/j.ebiom.2015.07.028 · Cited by 25 · see citing works

Mutation screening of IRF6 among families with non-syndromic oral clefts and identification of two novel variants: Review of the literature

Salahshourifar, I., Sulaiman, W. A. W., Halim, A. S., & Zilfalil, B. A. (2012) · European Journal of Medical Genetics · doi:10.1016/j.ejmg.2012.02.006 · Cited by 24 · see citing works

A complex immunodeficiency is based on U1 snRNP‐mediated poly(A) site suppression

Langemeier, J., Schrom, E.-M., Rabner, A., Radtke, M., Zychlinski, D., Saborowski, A. L., Bohn, G., Mandel‐Gutfreund, Y., Bodem, J., Klein, C., et al. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.252 · Cited by 24 · see citing works

Evolutionary Constraint Helps Unmask a Splicing Regulatory Region in BRCA1 Exon 11

Raponi, M., Douglas, A. G. L., Tammaro, C., Wilson, D. I., & Baralle, D. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037255 · Cited by 24 · see citing works

An Integrated Regulatory Network Reveals Pervasive Cross-Regulation among Transcription and Splicing Factors

Kosti, I., Predrag Radivojac, A., & Mandel‐Gutfreund, Y. (2012) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002603 · Cited by 20 · see citing works

Genetic determinants of immunogenicity to factor IX during the treatment of haemophilia B

Saini, S., Hamasaki‐Katagiri, N., Pandey, G. S., Yanover, C., Guelcher, C., Simhadri, V. L., Dandekar, S., Guerrera, M. F., Kimchi‐Sarfaty, C., & Sauna, Z. E. (2014) · Haemophilia · doi:10.1111/hae.12553 · Cited by 20 · see citing works

Discovery of a Novel CIP2A Variant (NOCIVA) with Clinical Relevance in Predicting TKI Resistance in Myeloid Leukemias

Mäkelä, E., Pavic, K., Varila, T., Salmenniemi, U., Löyttyniemi, E., Nagelli, S. G., Ammunét, T., Kähäri, V.-M., Clark, R. E., Elo, L. L., et al. (2021) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-20-3679 · Cited by 18 · see citing works

Comprehensive Network Analysis Reveals Alternative Splicing-Related lncRNAs in Hepatocellular Carcinoma

Wang, J., Wang, X., Bhat, A., Chen, Y., Xu, K., Mo, Y., Yi, S., & Zhou, Y. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.00659 · Cited by 16 · see citing works

Incorporating Evolutionary Information and Functional Domains for Identifying RNA Splicing Factors in Humans

Hsu, J. B., Bretaña, N. A., Lee, T.-Y., & Huang, H. (2011) · PLoS ONE · doi:10.1371/journal.pone.0027567 · Cited by 16 · see citing works

Hybrid splicing minigene and antisense oligonucleotides as efficient tools to determine functional protein/RNA interactions

Cywoniuk, P., Taylor, K., Sznajder, Ł. J., & Sobczak, K. (2017) · Scientific Reports · doi:10.1038/s41598-017-17816-x · Cited by 16 · see citing works

Gene Expression Profiles Controlled by the Alternative Splicing Factor Nova2 in Endothelial Cells

Belloni, E., Matteo, A. D., Pradella, D., Vacca, M., Wyatt, C. D. R., Alfieri, R. R., Maffia, A., Sabbioneda, S., & Ghigna, C. (2019) · Cells · doi:10.3390/cells8121498 · Cited by 15 · see citing works

Coexpression and Cosplicing Network Approaches for the Study of Mammalian Brain Transcriptomes

Iancu, O. D., Colville, A. M., Darakjian, P., & HITZEMANN, R. J. (2014) · International review of neurobiology · doi:10.1016/b978-0-12-801105-8.00004-7 · Cited by 12 · see citing works

Mutational analysis of SCN5A gene in long QT syndrome

Qureshi, S. F., Ali, A., John, P., Jadhav, A. P., Ananthapur, V., Rao, H. B., Jayakrishnan, M. P., Narasimhan, C., Shenthar, J., Kumarasamy Thangaraj, K., et al. (2015) · Meta Gene · doi:10.1016/j.mgene.2015.07.010 · Cited by 14 · see citing works

Association of an intronic SNP rs9939609 in FTO gene with type 2 diabetes mellitus among Bangladeshi population: A case–control study combined with updated meta-analysis

Kar, K., Munim, M. A., Fariha, A., Roy, A. S., Rahman, M. I., Akter, S., Tonmoy, M. I. Q., Alam, M. R., Raunak, A. I. B., Selim, S., et al. (2022) · Human Gene · doi:10.1016/j.humgen.2022.201133 · Cited by 13 · see citing works

Haplotype-specific MAPT exon 3 expression regulated by common intronic polymorphisms associated with Parkinsonian disorders

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Gene Fusions Derived by Transcriptional Readthrough are Driven by Segmental Duplication in Human

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Decoding Abnormal Splicing Code in Human Diseases

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Targeting natural splicing plasticity of APOBEC3B restricts its expression and mutagenic activity

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