Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 3,709

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

Open access
Metsalu, Tauno, Vilo, Jaak·2015·Nucleic Acids Research

Abstract

The Principal Component Analysis (PCA) is a widely used method of reducing the dimensionality of high-dimensional data, often followed by visualizing two of the components on the scatterplot. Although widely used, the method is lacking an easy-to-use web interface that scientists with little programming skills could use to make plots of their own data. The same applies to creating heatmaps: it is possible to add conditional formatting for Excel cells to show colored heatmaps, but for more advanced features such as clustering and experimental annotations, more sophisticated analysis tools have to be used. We present a web tool called ClustVis that aims to have an intuitive user interface. Users can upload data from a simple delimited text file that can be created in a spreadsheet program. It is possible to modify data processing methods and the final appearance of the PCA and heatmap plots by using drop-down menus, text boxes, sliders etc. Appropriate defaults are given to reduce the time needed by the user to specify input parameters. As an output, users can download PCA plot and heatmap in one of the preferred file formats. This web server is freely available at http://biit.cs.ut.ee/clustvis/.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1093/nar/gkv468

Cites

4 of 4 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 4 references

Research works printed but not linked: 19

  1. 10.1371/journal.pcbi.1002375 · DOI · Paper page
  2. 10.1136/jcp.2007.048991 · doi:10.1136/jcp.2007.048991
  3. Jolliffe, 2002, Principal component analysis
  4. 10.1093/bioinformatics/bts439 · DOI
  5. 10.1093/nar/gkg091 · DOI · Paper page
  6. 10.2307/1390807 · DOI
  7. 10.1038/nmeth.2811 · DOI · Paper page
  8. 10.1093/bioinformatics/btm069 · DOI · Paper page
  9. Lê, 2008, FactoMineR: an R package for multivariate analysis, J. Stat. Softw., 25, 1, 10.18637/jss.v025.i01 · DOI · Paper page
  10. 10.1179/000870403235002042 · DOI · Paper page
  11. 10.1093/nar/gkr378 · DOI · Paper page
  12. Rokach, 2005, Clustering methods, 321, 10.1007/0-387-25465-X_15 · DOI · Paper page
  13. 10.1056/NEJMoa021967 · DOI · Paper page
  14. Street, 1993, Nuclear feature extraction for breast tumor diagnosis, 861
  15. 10.1111/j.1469-1809.1936.tb02137.x · DOI · Paper page
  16. 10.1186/gb-2009-10-12-r139 · DOI
  17. 10.1093/nar/28.1.27 · DOI · Paper page
  18. 10.1093/nar/gki072 · DOI · Paper page
  19. 10.1371/journal.pone.0018640 · DOI

Cited by

See all 3,709

Metadata

Authors
Metsalu, T., & Vilo, J.
Venue
Nucleic Acids Research
Published
2015-05-12
Volume
43
Issue
W1
Pages
W566-W570
ISSN
  • 0305-1048 (ISSN-L)
  • 1362-4962
OpenAlex
W1617495083
Cited by
3,709
References
4
FWCI
70.47
Type
journal article
Language
en
Open access
gold

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap. https://app.cochat.ai/papers/10.1093/nar/gkv468
The paper
Metsalu, T., & Vilo, J. (2015). ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap. Nucleic Acids Research. https://doi.org/10.1093/nar/gkv468

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.