Cited by 149Sperm and Testicular FunctionMale Reproductive Health StudiesReproductive Health and Technologies

Nutritional modifications in male infertility: a systematic review covering 2 decades

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Abstract

CONTEXT: Studies suggest that appropriate nutritional modifications can improve the natural conception rate of infertile couples. OBJECTIVES: The purpose of this study was to review the human trials that investigated the relation between nutrition and male infertility. DATA SOURCES: A comprehensive systematic review of published human studies was carried out by searching scientific databases. Article selection was carried out in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses. The American Dietetic Association Research Design and Implementation Checklist was also used for quality assessment. DATA EXTRACTION: A total of 502 articles were identified, of which 23 studies met the inclusion criteria. DATA SYNTHESIS: Results indicated that a healthy diet improves at least one measure of semen quality, while diets high in lipophilic foods, soy isoflavones, and sweets lower semen quality. CONCLUSION: The role of daily nutrient exposure and dietary quality needs to be highlighted in male infertility. Mechanistic studies addressing the responsible underlying mechanisms of action of dietary modifications are highly warranted. SYSTEMATIC REVIEW REGISTRATION: PROSPERO 2013: CRD42013005953. Available at: http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42013005953.

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Registry

Crossref · 10.1093/nutrit/nuv059

Cites

97 of 97 references verified0 citation errors · 0 not checkable

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  • Diets rich in vegetables, fruits, whole grains, fish, and poultry are linked to better fertility and higher live birth rates in women and improved semen quality in men, while unhealthy diets may have the opposite associations.

    “Evidence suggests that adherence to a diet rich in vegetables, fruits, whole grains, fish, and poultry is related to better fertility and higher live birth rates among women and improved semen quality in men, and unhealthy diets may have the opposite effect (Chiu 2018, Gaskins 2018a, Giahi 2016, Grieger 2018, Salas-Huetos 2017, Vujkovic 2010).”

    From Preconception lifestyle advice for people with infertility (2021) · cites this paper as Giahi 2016

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Authors
Giahi, L., Mohammadmoradi, S., Javidan, A., & Sadeghi, M. R.
Affiliations
University of Kentucky (US)
Venue
Nutrition Reviews
Published
2015-12-24
Volume
74
Issue
2
Pages
118-130
ISSN
  • 0029-6643 (ISSN-L)
  • 1753-4887
OpenAlex
W2257144942
Cited by
149
References
99
Citations by year
2026: 4 · 2025: 11 · 2024: 15 · 2023: 26 · 2022: 17 · 2021: 17 · 2020: 19 · 2019: 13 · 2018: 15 · 2017: 9 · 2016: 3
FWCI
1.35
Type
journal article
Language
en
Open access
Locations
  • Nutrition Reviews (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • HighWire Press Open Archive (submittedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
  • Health Sciences › Health Professions › General Health Professions › Male Reproductive Health Studies
  • Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
Keywords
male infertility, dietary change, semen quality, healthy eating, soy isoflavones, sweets, diet quality, spontaneous conception
MeSH terms
Diet, Humans, Infertility, Male, Isoflavones, Male, Nutritional Status, Dietary Sucrose, Semen Analysis

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