AERIAL DISSEMINATION OP PULMONARY TUBERCULOSIS: A TWO-YEAR STUDY OF CONTAGION IN A TUBERCULOSIS WARD1
Abstract
R. L. RILEY, C. C. MILLS, W. NYKA, N. WEINSTOCK, P. B. STOREY, L. U. SULTAN, M. C. RILEY, W. F. WELLS; AERIAL DISSEMINATION OP PULMONARY TUBERCULOSIS: A TW
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Like COVID-19, TB is an airborne disease spread through infectious aerosols generated by infected people; transmission risk was higher in South African homes with poor ventilation.
“Like COVID-19, TB is an airborne disease spread through infectious aerosols generated by infected people (140); for example, transmission risk was higher in South African homes with poor ventilation (98).”
From Review of the Impact of Housing Quality on Inequalities in Health and Well-Being (2023) · cites this paper as [140]
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Siegel, J. D., Rhinehart, E., Jackson, M. M., & Chiarello, L. A. (2007) · American Journal of Infection Control · doi:10.1016/j.ajic.2007.10.007 · Cited by 3,457 · see citing works
Airborne transmission of respiratory viruses
Wang, C. C., Prather, K. A., Sznitman, J., Jimenez, J. L., Lakdawala, S. S., Tüfekçi, Z., & Marr, L. C. (2021) · Science · doi:10.1126/science.abd9149 · Cited by 1,552 · see citing works
“Anecdotal observationsofmeasles virus (16–18) andMycobacterium tuberculosis (51, 52) infection in close proximity, previously attributed solely to droplets, include transmission by aerosols at short range.”
BackgroundNahid, P., Dorman, S. E., Alipanah, N., Barry, P. M., Brożek, J., Cattamanchi, A., Chaisson, L. H., Chaisson, R. E., Daley, C. L., Grzemska, M., et al. (2016) · Clinical Infectious Diseases · doi:10.1093/cid/ciw376 · Cited by 1,492 · see citing works
Gandhi, N. R., Nunn, P. P., Dheda, K. U. J., Schaaf, H. S., Matteo Zignol, E., van Soolingen, D., Jensen, P. A., & Bayona, J. N. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60410-2 · Cited by 1,019 · see citing works
Transmissibility and transmission of respiratory viruses
Leung, N. H. L. (2021) · Nature Reviews Microbiology · doi:10.1038/s41579-021-00535-6 · Cited by 890 · see citing works
Transmission of Mycobacterium tuberculosis from patients smear-negative for acid-fast bacilli
Behr, M. A., Warren, S., Salamon, H., Hopewell, P. C., Ponce‐de‐León, A., Daley, C. L., & Small, P. M. (1999) · The Lancet · doi:10.1016/s0140-6736(98)03406-0 · Cited by 751 · see citing works
Recognition of aerosol transmission of infectious agents: a commentary
Tellier, R., Li, Y., Cowling, B. J., & Tang, J. W.-T. (2019) · BMC Infectious Diseases · doi:10.1186/s12879-019-3707-y · Cited by 745 · see citing works
“For tuberculosis (TB), definitive experimental evidence of airborne transmission being necessary and sufficient to cause disease was provided in a series of guinea-pig experiments [30, 31] , which has been repeated more recently in a slightly different clinical context [32] .”
BackgroundTransmission of influenza A in human beings
Brankston, G., Gitterman, L., Hirji, Z., Lemieux, C., & Gardam, M. A. (2007) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(07)70029-4 · Cited by 743 · see citing works
Prevention of M. tuberculosis Infection with H4:IC31 Vaccine or BCG Revaccination
Nemes, E., Geldenhuys, H. D., Rozot, V., Rutkowski, K. T., Ratangee, F., Bilek, N., Mabwe, S., Makhethe, L., Erasmus, M., Toefy, A., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1714021 · Cited by 653 · see citing works
Mack, U., Migliori, G. B., Sester, M., et al. (2009) · European Respiratory Journal · doi:10.1183/09031936.00120908 · Cited by 593 · see citing works
The History of Ultraviolet Germicidal Irradiation for Air Disinfection
Reed, N. G. (2010) · Public Health Reports · doi:10.1177/003335491012500105 · Cited by 442 · see citing works
The Host Immune Response to Tuberculosis
Schluger, N. W., & Rom, W. N. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.157.3.9708002 · Cited by 420 · see citing works
Aerobiology and Its Role in the Transmission of Infectious Diseases
Fernstrom, A., & Goldblatt, M. (2013) · Journal of Pathogens · doi:10.1155/2013/493960 · Cited by 366 · see citing works
What We Know About Tuberculosis Transmission: An Overview
Churchyard, G., Kim, P. S., Shah, N., Rustomjee, R., Gandhi, N. R., Mathema, B., Dowdy, D. W., Kasmar, A. G., & Cárdenas, V. (2017) · The Journal of Infectious Diseases · doi:10.1093/infdis/jix362 · Cited by 341 · see citing works
Cough-generated Aerosols of Mycobacterium tuberculosis
Fennelly, K. P., Martyny, J. W., Fulton, K. E., Orme, I. M., Cave, D. M., & Heifets, L. B. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200308-1101oc · Cited by 326 · see citing works
Cole, E. C., & Cook, C. E. (1998) · American Journal of Infection Control · doi:10.1016/s0196-6553(98)70046-x · Cited by 317 · see citing works
Transmission of tubercle bacilli: The effects of chemotherapy
Rouillon, A., Perdrizet, S., & Parrot, R. (1976) · Tubercle · doi:10.1016/s0041-3879(76)80006-2 · Cited by 311 · see citing works
Lange, C. G., Abubakar, I., Alffenaar, J. C., Bothamley, G. H., Caminero, J. A., Carvalho, A. C. C., Chang, K. C., Codecasa, L. R., Correia, A., Crudu, V., et al. (2014) · European Respiratory Journal · doi:10.1183/09031936.00188313 · Cited by 308 · see citing works
Immunopathology of tuberculosis: roles of macrophages and monocytes
Fenton, M. J., & Vermeulen, M. W. (1996) · Infection and Immunity · doi:10.1128/iai.64.3.683-690.1996 · Cited by 303 · see citing works
Raboud, J., Shigayeva, A., McGeer, A., Bontovics, E., Chapman, M., Gravel, D., Henry, B., Lapinsky, S. E., Loeb, M. B., McDonald, L. C., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010717 · Cited by 297 · see citing works
Adverse Health Effects Among Adults Exposed to Home Dampness and Molds
Dales, R., Burnett, R., & Zwanenburg, H. (1991) · American Review of Respiratory Disease · doi:10.1164/ajrccm/143.3.505 · Cited by 299 · see citing works
Sung, J. C., Padilla, D. J., Garcia‐Contreras, L., VerBerkmoes, J. L., Durbin, D., Peloquin, C. A., Elbert, K. J., Hickey, A. J., & Edwards, D. A. (2009) · Pharmaceutical Research · doi:10.1007/s11095-009-9894-2 · Cited by 245 · see citing works
“tuberculosis (2) and subsequent uptake of the bacterium by alveolar macrophages (3).”
Palmer, S. M., Robinson, L. J., Wang, A., Gossage, J. R., Bashore, T. M., & Tapson, V. F. (1998) · CHEST Journal · doi:10.1378/chest.113.1.237 · Cited by 237 · see citing works
Hospital Ventilation and Risk for Tuberculous Infection in Canadian Health Care Workers
Menzies, D., Fanning, A., Yuan, L., FitzGerald, J. M., & and the Canadian Collaborative Group in Nosocomial Transmission of TB* (2000) · Annals of Internal Medicine · doi:10.7326/0003-4819-133-10-200011210-00010 · Cited by 212 · see citing works
“Sound theoretical reasons (36), laboratory (10) and animal (11) experiments, and numerous outbreak reports (3–9) suggest that ventilation is an important determinant of nosocomial transmission of tuberculosis.”
BackgroundResultYuen, C. M., Amanullah, F., Dharmadhikari, A., Nardell, E. A., Seddon, J. A., Vasilyeva, I. A., Zhao, Y., Keshavjee, S. A., & Becerra, M. C. (2015) · The Lancet · doi:10.1016/s0140-6736(15)00322-0 · Cited by 201 · see citing works
“[33] [34] [35] [36] Epidemiologically, the continuing transmission of drugresistant strains that results from diagnostic failure or an absence of eff ective treatment is suggested by the prevalence of drug resistance in patients who have never”
The transmission of Mycobacterium tuberculosis in high burden settings
Yates, T., Khan, P. Y., Knight, G. M., Taylor, J., McHugh, T. D., Lipman, M. C. I., White, R. G., Cohen, T., Cobelens, F. G. J., Wood, R., et al. (2016) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(15)00499-5 · Cited by 195 · see citing works
The Epidemiology of Tuberculosis Infection in a Closed Environment
Houk, V. N., Baker, J. H., Sorensen, K., et al. (1968) · Archives of Environmental Health An International Journal · doi:10.1080/00039896.1968.10665011 · Cited by 192 · see citing works
The Epidemiological Importance of Subclinical Tuberculosis. A Critical Reappraisal
Kendall, E. A., Shrestha, S., & Dowdy, D. W. (2021) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202006-2394pp · Cited by 185 · see citing works
The Infectiousness of Tuberculosis Patients Coinfected with HIV
Escombe, A. R., Moore, D., Gilman, R. H., Pan, W., Ñavincopa, M., Ticona, E., Gil, C. M., Caviedes, L., Sheen, P., Gonzalez, A. E., et al. (2008) · PLoS Medicine · doi:10.1371/journal.pmed.0050188 · Cited by 183 · see citing works
Pathogenesis of tuberculosis: pathway to apical localization
Balasubramanian, V., Wiegeshaus, E. H., Taylor, B. T., & Smith, D. W. (1994) · Tubercle and Lung Disease · doi:10.1016/0962-8479(94)90002-7 · Cited by 177 · see citing works
What Does Tuberculin Reactivity after Bacille Calmette-Guérin Vaccination Tell Us?
Menzies, D. (2000) · Clinical Infectious Diseases · doi:10.1086/314075 · Cited by 174 · see citing works
Dharmadhikari, A., Mphahlele, M., Stoltz, A. C., Venter, K., Mathebula, R., Masotla, T., Lubbe, W. F., Pagano, M., First, M. W., Jensen, P. A., et al. (2012) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201107-1190oc · Cited by 170 · see citing works
Li, H., Wang, X.-X., Wang, B., Fu, L., Liu, G., Lu, Y., Cao, M., Huang, H., & Javid, B. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1611776114 · Cited by 169 · see citing works
Tuberculosis Vaccines and Prevention of Infection
Hawn, T. R., Day, T. A., Scriba, T. J., Hatherill, M., Hanekom, W. A., Evans, T. G., Churchyard, G. J., Kublin, J. G., Bekker, L.-G., & Self, S. G. (2014) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00021-14 · Cited by 164 · see citing works
How Contagious Is Tuberculosis?
Sepkowitz, K. A. (1996) · Clinical Infectious Diseases · doi:10.1093/clinids/23.5.954 · Cited by 162 · see citing works
“The group headed by Riley made the most valiant attempts to study the question of tuberculosis transmission scientifically [62-64].”
BackgroundInfluentialTuberculosis Outbreak in a General Hospital: Evidence for Airborne Spread of Infection
Ehrenkranz, N. J., & KICKLIGHTER, J. L. (1972) · Annals of Internal Medicine · doi:10.7326/0003-4819-77-3-377 · Cited by 162 · see citing works
Cough and the Transmission of Tuberculosis
Turner, R. D., & Bothamley, G. H. (2014) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiu625 · Cited by 159 · see citing works
Review of the Impact of Housing Quality on Inequalities in Health and Well-Being
Howden-Chapman, P., Bennett, J., Edwards, R., Jacobs, D., Nathan, K., & Ormandy, D. (2023) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-071521-111836 · Cited by 153 · see citing works
Sampson, S. L., Dascher, C. C., Sambandamurthy, V. K., Russell, R. G., Jacobs, W. R., Bloom, B. R., & Hondalus, M. K. (2004) · Infection and Immunity · doi:10.1128/iai.72.5.3031-3037.2004 · Cited by 153 · see citing works
Rapid impact of effective treatment on transmission of multidrug-resistant tuberculosis
Dharmadhikari, A. S., Mphahlele, M., Venter, K., Stoltz, A. C., Mathebula, R., Masotla, T., der Walt, M. L. V., Pagano, M., Jensen, P. A., & Nardell, E. A. (2014) · The International Journal of Tuberculosis and Lung Disease · doi:10.5588/ijtld.13.0834 · Cited by 149 · see citing works
Williams, C. M., Abdulwhhab, M., Birring, S. S., De Kock, E., Garton, N. J., Townsend, E., Pareek, M., Al-Taie, A., Pan, J., Ganatra, R., et al. (2020) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(19)30707-8 · Cited by 142 · see citing works
Gupta, U. D., & Katoch, V. M. (2005) · Tuberculosis · doi:10.1016/j.tube.2005.08.008 · Cited by 146 · see citing works
Smith, P. G., & Moss, A. R. (2014) · Tuberculosis · doi:10.1128/9781555818357.ch4 · Cited by 142 · see citing works
The M Cell as a Portal of Entry to the Lung for the Bacterial Pathogen Mycobacterium tuberculosis
Teitelbaum, R., Schubert, W., Gunther-Cummins, L., Kress, Y., Macaluso, F., Pollard, J. W., McMurray, D. N., & Bloom, B. R. (1999) · Immunity · doi:10.1016/s1074-7613(00)80063-1 · Cited by 139 · see citing works
Guinea Pig Model of Tuberculosis
McMurray, D. N. (2014) · ASM Press eBooks · doi:10.1128/9781555818357.ch9 · Cited by 139 · see citing works
Escombe, A. R., Oeser, C., Gilman, R. H., Ñavincopa, M., Ticona, E., Martinez, C., Caviedes, L., Sheen, P., Gonzalez, A. E., Noakes, C. J., et al. (2007) · Clinical Infectious Diseases · doi:10.1086/515397 · Cited by 137 · see citing works
“ies written or cowritten by Riley [15, 16, 30], all patients in”
BackgroundResultPlumlee, C. R., Duffy, F. J., Gern, B. H., Delahaye, J. L., Cohen, S. B., Stoltzfus, C. R., Rustad, T. R., Hansen, S. G., Axthelm, M. K., Picker, L. J., et al. (2020) · Cell Host & Microbe · doi:10.1016/j.chom.2020.10.003 · Cited by 135 · see citing works
“In a classic study in which guinea pigs were used as monitors of effluent air from a six-bed TB ward over a 2year period, 71 of the 158 guinea pigs converted to a positive tuberculin test, and upon necropsy, 69/71 of these animals contained a single pulmonary granuloma (O’Grady and Riley, 1963; Riley et al., 1959).”
BackgroundMethodMigliori, G. B., Nardell, E. A., Yedilbayev, A., et al. (2019) · European Respiratory Journal · doi:10.1183/13993003.00391-2019 · Cited by 131 · see citing works
“Observational studies done in the pre-MDR era demonstrated that anti-TB chemotherapy can rapidly render patients non-infectious [52-54,78-82].”
BackgroundInfluentialAntibodies and tuberculosis: finally coming of age?
Li, H., & Javid, B. (2018) · Nature reviews. Immunology · doi:10.1038/s41577-018-0028-0 · Cited by 113 · see citing works
What Animal Models Teach Humans about Tuberculosis
Dharmadhikari, A., & Nardell, E. A. (2008) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2008-0154tr · Cited by 113 · see citing works
Mphaphlele, M., Dharmadhikari, A., Jensen, P. A., et al. (2015) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201501-0060oc · Cited by 112 · see citing works
Predicting Extensively Drug-Resistant Mycobacterium tuberculosis Phenotypes with Genetic Mutations
Rodwell, T. C., Valafar, F., Douglas, J. T., et al. (2013) · Journal of Clinical Microbiology · doi:10.1128/jcm.02701-13 · Cited by 106 · see citing works
“Since empirical studies have clearly demonstrated that early treatment with appropriate therapy can halt TB transmission almost immediately, while undetected, inappropriately treated DR TB continues to be transmitted (5, 44), adopting imperfect but effective rapid diagnostic methods may help reduce transmission and is…”
BackgroundMinimum Infective Dose of Mycobacterium bovis in Cattle
Dean, G. S., Rhodes, S. G., Coad, M., et al. (2005) · Infection and Immunity · doi:10.1128/iai.73.10.6467-6471.2005 · Cited by 106 · see citing works
Tuberculosis Infectiousness and Host Susceptibility
Turner, R. D., Chiu, C., Churchyard, G., Esmail, H., Lewinsohn, D. M., Gandhi, N. R., & Fennelly, K. P. (2017) · The Journal of Infectious Diseases · doi:10.1093/infdis/jix361 · Cited by 102 · see citing works
Yassi, A., Moore, D. M., FitzGerald, J. M., Bigelow, P., Hon, C., & Bryce, E. (2005) · Journal of Occupational and Environmental Medicine · doi:10.1097/01.jom.0000150207.18085.41 · Cited by 93 · see citing works
Tuberculosis Infection and Latent Tuberculosis
Lee, S. H. (2016) · Tuberculosis & respiratory diseases · doi:10.4046/trd.2016.79.4.201 · Cited by 93 · see citing works
Transmission and Institutional Infection Control of TuberculosisPreprint
Nardell, E. A. (2015) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a018192 · Cited by 91 · see citing works
“In his initial 2-yr human to guinea pig study in the late 1950s, Riley et al. (1995) found that transmission occurred primarily (21 of 22 infections) from chronic patients, on treatment, but resistant to one or more of the three available antibiotics at the time.”
BackgroundMikszewski, A., Stabile, L., Buonanno, G., & Morawska, L. (2021) · Geoscience Frontiers · doi:10.1016/j.gsf.2021.101285 · Cited by 87 · see citing works
Natural infection of guinea pigs exposed to patients with highly drug-resistant tuberculosis
Dharmadhikari, A., Basaraba, R. J., der Walt, M. L. V., Weyer, K., Mphahlele, M., Venter, K., Jensen, P. A., First, M. W., Parsons, S., McMurray, D. N., et al. (2011) · Tuberculosis · doi:10.1016/j.tube.2011.03.002 · Cited by 87 · see citing works
Mycobacterium tuberculosis Transmission in High-Incidence Settings—New Paradigms and Insights
Coleman, M. C., Martínez, L., Theron, G., Wood, R., & Marais, B. J. (2022) · Pathogens · doi:10.3390/pathogens11111228 · Cited by 102 · see citing works
Du, C., Wang, S., Yu, M., Chiu, T., Wang, J., Chuang, P., Jou, R., Chan, P., & Fang, C. (2020) · Indoor Air · doi:10.1111/ina.12639 · Cited by 84 · see citing works
Respiratory infection risk-based ventilation design method
Kurnitski, J., Kiil, M., Wargocki, P. L., Boerstra, A., Seppänen, O., Olesen, B. W., & Morawska, L. (2021) · Building and Environment · doi:10.1016/j.buildenv.2021.108387 · Cited by 83 · see citing works
Tjärnlund, A., Rodrı́guez, A., Cardona, P.-J., et al. (2006) · International Immunology · doi:10.1093/intimm/dxl017 · Cited by 84 · see citing works
Transmission of drug-resistant tuberculosis in HIV-endemic settings
Khan, P. Y., Yates, T., Osman, M., Warren, R. M., van der Heijden, Y. F., Padayatchi, N., Nardell, E. A., Moore, D., Mathema, B., Gandhi, N. R., et al. (2018) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(18)30537-1 · Cited by 80 · see citing works
What was the primary mode of smallpox transmission? Implications for biodefense
Milton, D. K. (2012) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2012.00150 · Cited by 78 · see citing works
“Thus, smallpox cannot be classified as an "obligate" airborne infectious disease, such as tuberculosis (Riley et al., 1995) (sometimes referred to as a "true" airborne infection), because it was capable of initiating disease via infection of tissues outside of the lower respiratory tract.”
BackgroundCommunity-Based Outbreaks of Tuberculosis
Raffalli, J. T. (1996) · Archives of Internal Medicine · doi:10.1001/archinte.1996.00040041053002 · Cited by 80 · see citing works
Walker, T. M., Monk, P., Smith, E. G., & Peto, T. (2013) · Clinical Microbiology and Infection · doi:10.1111/1469-0691.12183 · Cited by 74 · see citing works
What Animal Models Can Teach Us About the Pathogenesis of Tuberculosis in Humans
Smith, D. W., & Wiegeshaus, E. H. (1989) · Clinical Infectious Diseases · doi:10.1093/clinids/11.supplement_2.s385 · Cited by 76 · see citing works
Chang, K. C., & Yew, W.-W. (2012) · Respirology · doi:10.1111/j.1440-1843.2012.02257.x · Cited by 75 · see citing works
Lovey, A., Verma, S., Kaipilyawar, V., Ribeiro‐Rodrigues, R., Husain, S., Palaci, M., Dietze, R., Ma, S., Morrison, R. D., Sherman, D. R., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28506-2 · Cited by 73 · see citing works
Nardell, E. A., & Dharmadhikari, A. (2010) · PubMed · Cited by 71 · see citing works
Restrepo, B. I., Fisher‐Hoch, S. P., Smith, B., et al. (2008) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2008.79.541 · Cited by 71 · see citing works
“Although infectiousness is thought to be reduced before smear or culture conversion, a delay in clearance measured by culture positivity could translate into increased exposure in the community, particularly one where there are large numbers of DM patients.(16,17) In a population such as ours where we now find prospec…”
BackgroundBeggs, C. B., Shepherd, S. J., & Kerr, K. G. (2010) · BMC Infectious Diseases · doi:10.1186/1471-2334-10-247 · Cited by 71 · see citing works
“undertook a study in a well-ventilated TB ward in a Baltimore, MD Hospital, from which they estimated that ‘one unit of infection’ was suspended in every 15 000-20 000 ft(3) (500-667 m(3)) of air in the ward [2].”
BackgroundAirborne Nosocomial Infection: A Contemporary Perspective
Eickhoff, T. C. (1994) · Infection Control and Hospital Epidemiology · doi:10.1086/646830 · Cited by 71 · see citing works
Bothamley, G. H. (2002) · Thorax · doi:10.1136/thorax.57.1.45 · Cited by 71 · see citing works
Martinez, L., Verma, R., Croda, J., Horsburgh, C. R., Walter, K. S., Degner, N., Middelkoop, K., Koch, A., Hermans, S., Warner, D. F., et al. (2019) · European Respiratory Journal · doi:10.1183/13993003.02302-2018 · Cited by 70 · see citing works
Indoor environmental control of tuberculosis and other airborne infections
Nardell, E. A. (2015) · Indoor Air · doi:10.1111/ina.12232 · Cited by 69 · see citing works
Burden of tuberculosis in Kampala, Uganda.
Guwatudde, D., Zalwango, S. K., Kamya, M. R., Debanne, S. M., Diaz, M., Okwera, A., Mugerwa, R. D., King, C. H., & Whalen, C. C. (2003) · Europe PMC (PubMed Central) · Cited by 68 · see citing works
Ultra-low dose of Mycobacterium tuberculosis aerosol creates partial infection in mice
Saini, D., Hopkins, G., Seay, S. A., Chen, C.-J., Perley, C. C., Click, E. M., & Frothingham, R. (2011) · Tuberculosis · doi:10.1016/j.tube.2011.11.007 · Cited by 66 · see citing works
Dwellings, crowding, and tuberculosis in Montreal
Wanyeki, I., Olson, S., Brassard, P., et al. (2006) · Social Science & Medicine · doi:10.1016/j.socscimed.2005.12.015 · Cited by 65 · see citing works
Pyrazinamide-Monoresistant Mycobacterium tuberculosis in the United States
Hannan, M. M., Desmond, E. P., Morlock, G. P., et al. (2001) · Journal of Clinical Microbiology · doi:10.1128/jcm.39.2.647-650.2001 · Cited by 65 · see citing works
“tuberculosis is primarily transmitted by direct exposure to aerosolized infectious particles and is the major cause of human TB (8, 22, 23).”
BackgroundTuberculosis vaccines: barriers and prospects on the quest for a transformative tool
Karp, C. L., Wilson, C. B., & Stuart, L. M. (2015) · Immunological Reviews · doi:10.1111/imr.12270 · Cited by 62 · see citing works
Boom, W. H. (1999) · Microbes and Infection · doi:10.1016/s1286-4579(99)80033-1 · Cited by 62 · see citing works
Infectivity of sputum-positive tuberculous patients on chemotherapy.
Gunnels, J. J., Jh, B., & Swindoll, H. (1974) · PubMed · doi:10.1164/arrd.1974.109.3.323 · Cited by 62 · see citing works
Chaudhuri, R. R., Ren, C.-P., Desmond, L., et al. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000352 · Cited by 61 · see citing works
Face Mask Sampling for the Detection of Mycobacterium tuberculosis in Expelled Aerosols
Williams, C., Cheah, E. S. G., Malkin, J., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0104921 · Cited by 60 · see citing works
PERSONAL RESPIRATORY PROTECTION AGAINST MYCOBACTERIUM TUBERCULOSIS
Fennelly, K. P. (1997) · Clinics in Chest Medicine · doi:10.1016/s0272-5231(05)70352-x · Cited by 60 · see citing works
IgA and FcαRI: Versatile Players in Homeostasis, Infection, and Autoimmunity
van Gool, M. M. J., & van Egmond, M. (2021) · ImmunoTargets and Therapy · doi:10.2147/itt.s266242 · Cited by 59 · see citing works
TB or Not TB: That Is No Longer the Question
Modlin, R. L., & Bloom, B. R. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3007402 · Cited by 56 · see citing works
“The number of Mtb bacilli required to cause disease in humans is estimated to range from 1 to 400 bacilli (43), a number sufficiently small that, in many individuals, infection may be eliminated by innate responses without enough bacterial antigen load developing to stimulate T cell responses.”
BackgroundNocardia asteroides infection—a transmissible disease
Houang, E. T. S., Lovett, I. S., Thompson, F. D., et al. (1980) · Journal of Hospital Infection · doi:10.1016/0195-6701(80)90029-8 · Cited by 55 · see citing works
Field test of a novel detection device for Mycobacterium tuberculosis antigen in cough
McNerney, R., Wondafrash, B. A., Amena, K., et al. (2010) · BMC Infectious Diseases · doi:10.1186/1471-2334-10-161 · Cited by 53 · see citing works
“Previous attempts to assess airborne transmission have relied on exposure of guinea pigs to hospitalized TB patients [11,12].”
BackgroundWood, R., Morrow, C. D., Barry, C. E., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0146658 · Cited by 53 · see citing works
Nanotechnology in Tuberculosis: State of the Art and the Challenges Ahead
Grotz, E., Tateosian, N. L., Amiano, N. O., Cagel, M., Bernabeu, E., Chiappetta, D. A., & Moretton, M. A. (2018) · Pharmaceutical Research · doi:10.1007/s11095-018-2497-z · Cited by 55 · see citing works
Hand-foot-and-mouth disease and weather factors in Guangzhou, southern China
Li, T.-P., Yang, Z., Di, B., & Wang, M. (2013) · Epidemiology and Infection · doi:10.1017/s0950268813002938 · Cited by 50 · see citing works
Chapter 2: Transmission and pathogenesis of tuberculosis
Long, R., Divangahi, M., & Schwartzman, K. (2022) · Canadian Journal of Respiratory Critical Care and Sleep Medicine · doi:10.1080/24745332.2022.2035540 · Cited by 54 · see citing works
Mastorides, S., Oehler, R. L., Greene, J. N., Sinnott, J. T., Kranik, M., & Sandin, R. L. (1999) · CHEST Journal · doi:10.1378/chest.115.1.19 · Cited by 50 · see citing works
Verma, S., Bhatt, K., Lovey, A., Ribeiro‐Rodrigues, R., Durbin, J. E., Jones‐López, E. C., Palaci, M., Vinhas, S. A., Alland, D., Dietze, R., et al. (2019) · PLoS Pathogens · doi:10.1371/journal.ppat.1007613 · Cited by 49 · see citing works
Research and development of new tuberculosis vaccines: a review
Schrager, L. K., Harris, R. C., & Vekemans, J. (2018) · F1000Research · doi:10.12688/f1000research.16521.1 · Cited by 49 · see citing works
Environmental control of tuberculosis
Nardell, E. A. (1993) · Medical Clinics of North America · doi:10.1016/s0025-7125(16)30196-1 · Cited by 48 · see citing works
Environmental Control of Tuberculosis: Continuing Controversy
Segal‐Maurer, S., & Kalkut, G. (1994) · Clinical Infectious Diseases · doi:10.1093/clinids/19.2.299 · Cited by 47 · see citing works
“, duration of contact and number of organisms required) and the likelihood of infection [22, 24, 30, 33, 37-44].”
Background
- Authors
- RILEY, R. L., MILLS, C. C., NYKA, W., WEINSTOCK, N., STOREY, P. B., SULTAN, L. U., RILEY, M. C., & WELLS, W. F.
- ORCID
- RILEY, M. C.
- Venue
- American Journal of Epidemiology
- Publisher
- Oxford University Press (OUP)
- Published
- 1995-07-01
- Volume
- 142
- Issue
- 1
- Pages
- 3-14
- ISSN
- 0002-9262 (ISSN-L)
- 1476-6256
- OpenAlex
- W1858778993
- Cited by
- 269
- References
- 0
- Citations by year
- 2026: 5 · 2025: 6 · 2024: 12 · 2023: 5 · 2022: 12 · 2021: 15 · 2020: 15 · 2019: 14 · 2018: 10 · 2017: 9 · 2016: 13 · 2015: 10 · 2014: 13 · 2013: 8 · 2012: 7
- FWCI
- 4.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Infection Control and Ventilation
- Health Sciences › Medicine › Infectious Diseases › Infection Control in Healthcare
- Keywords
- pulmonary tuberculosis, airborne transmission, tuberculosis ward, hospital infection control
- MeSH terms
- Animals, Cross Infection, Humans, Research Design, Tuberculosis, Pulmonary, Disease Transmission, Infectious, History, 20th Century
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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