Free Radical-Independent Protection by Nerve Growth Factor and Bcl-2 of PC12 Cells from Hydrogen Peroxide-Triggered Apoptosis

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

Wyllie, A. H. (1980) · Nature · doi:10.1038/284555a0 · Cited by 4,499

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF‐kappa B transcription factor and HIV‐1.

Schreck, R., RIEBER, P., & Baeuerle, P. A. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb07761.x · Cited by 3,793

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

Hockenbery, D. M., Oltvai, Z. N., Yin, X., Milliman, C. L., & Korsmeyer, S. J. (1993) · Cell · doi:10.1016/0092-8674(93)80066-n · Cited by 3,402

Cell death during development of the nervous system

Oppenheim, R. W. (1991) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.14.030191.002321 · Cited by 3,084

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme

Ji, Y. (1993) · Cell · doi:10.1016/0092-8674(93)90485-9 · Cited by 2,497

Genetic control of programmed cell death in the nematode C. elegans

Ellis, H. (1986) · Cell · doi:10.1016/0092-8674(86)90004-8 · Cited by 1,828

Developmental cell death: morphological diversity and multiple mechanisms

Clarke, P. H. (1990) · Anatomy and Embryology · doi:10.1007/bf00174615 · Cited by 1,695

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

Kane, D. J., Sarafian, T. A., Anton, R., Hahn, H., Gralla, E. B., Valentine, J. S., Örd, T., & Bredesen, D. E. (1993) · Science · doi:10.1126/science.8235659 · Cited by 1,671

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

Abate, C., Patel, L., Rauscher, F. J., & Curran, T. (1990) · Science · doi:10.1126/science.2118682 · Cited by 1,573

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2

Hengartner, M. O., & Horvitz, H. R. (1994) · Cell · doi:10.1016/0092-8674(94)90506-1 · Cited by 1,167

Reactive oxygen intermediates as mediators of programmed cell death in plants and animals

Jabs, T. (1999) · Biochemical Pharmacology · doi:10.1016/s0006-2952(98)00227-5 · Cited by 600

Thioredoxin Peroxidase Is a Novel Inhibitor of Apoptosis with a Mechanism Distinct from That of Bcl-2

Zhang, P., Liu, B., Kang, S. W., Seo, M. S., Rhee, S. G., & Obeid, L. M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.49.30615 · Cited by 370

Withania somnifera (L.) Dunal (Ashwagandha): A comprehensive review on ethnopharmacology, pharmacotherapeutics, biomedicinal and toxicological aspects

Paul, S., Chakraborty, S., Anand, U., Dey, S., Nandy, S., Ghorai, M., Saha, S. C., Patil, M. T., Kandimalla, R., Proćków, J., et al. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112175 · Cited by 306

Mechanisms underlying hypoxia-induced neuronal apoptosis

Banasiak, K. J., Xia, Y., & Haddad, G. G. (2000) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00011-3 · Cited by 306

Protective effects of salidroside on hydrogen peroxide-induced apoptosis in SH-SY5Y human neuroblastoma cells

Zhang, L., Yu, H., Sun, Y., Lin, X., Chen, B., Tan, C., Cao, G.-X., & Wang, Z. (2007) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.01.089 · Cited by 262

Cytoprotective effect of fucoxanthin isolated from brown algae Sargassum siliquastrum against H2O2-induced cell damage

Heo, S., Ko, S., Kang, S., Kang, H., Kim, J.-P., Kim, S.-H., Lee, K.-W., Cho, M.-G., & Jeon, Y. (2008) · European Food Research and Technology · doi:10.1007/s00217-008-0918-7 · Cited by 210

Alpinia protocatechuic acid protects against oxidative damage in vitro and reduces oxidative stress in vivo

Shi, G., An, L., Jiang, B., Guan, S., & Bao, Y. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.02.057 · Cited by 199

Action of the neurotrophins on calcium uptake

Jiang, H., & Guroff, G. (1997) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19971101)50:3 · Cited by 27

Protection against hydrogen peroxide-induced cytotoxicity in PC12 cells by scutellarin

Hong, H., & Liu, G. (2004) · Life Sciences · doi:10.1016/j.lfs.2003.09.074 · Cited by 186

Cobalt chloride induces PC12 cells apoptosis through reactive oxygen species and accompanied by AP‐1 activation

Zou, W., Yan, M., Xu, W., Huo, H., Sun, L., Zheng, Z., & Liu, X. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.1118 · Cited by 185

Is Hydrogen Peroxide a Suitable Apoptosis Inducer for All Cell Types?

Xiang, J., Wan, C., Guo, R., & Guo, D. (2016) · BioMed Research International · doi:10.1155/2016/7343965 · Cited by 162

Strawberry and Its Anthocyanins Reduce Oxidative Stress-Induced Apoptosis in PC12 Cells

Heo, H. J., & Lee, C. Y. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf048616l · Cited by 156

Relationships between neuronal death and the cellular redox status. Focus on the developing nervous system

Castagné, V. (1999) · Progress in Neurobiology · doi:10.1016/s0301-0082(99)00012-x · Cited by 136

Neuroprotective effect of astaxanthin on H2O2-induced neurotoxicity in vitro and on focal cerebral ischemia in vivo

Lu, Y., Liu, S., Sun, H., Wu, X., Li, J.-J., & Zhu, L. (2010) · Brain Research · doi:10.1016/j.brainres.2010.09.016 · Cited by 128

Loganin protects against hydrogen peroxide-induced apoptosis by inhibiting phosphorylation of JNK, p38, and ERK 1/2 MAPKs in SH-SY5Y cells

Kwon, S., Kim, J., Hong, S., Jung, Y., Kim, H., Lee, S., & Jang, C. (2011) · Neurochemistry International · doi:10.1016/j.neuint.2011.01.012 · Cited by 119

Generation of free radicals during lipid hydroperoxide-triggered apoptosis in PC12h cells

Aoshima, H., Satoh, T., Sakai, N., Yamada, M., Enokido, Y., Ikeuchi, T., & Hatanaka, H. (1997) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/s0005-2760(96)00159-2 · Cited by 111

Protective effects of ellagic and chlorogenic acids against oxidative stress in PC12 cells

Pavlica, S., & Gebhardt, R. (2005) · Free Radical Research · doi:10.1080/09670260500197660 · Cited by 107

Neuroprotective effects of PDGF against oxidative stress and the signaling pathway involved

Zheng, L., Ishii, Y., Tokunaga, A., Hamashima, T., Shen, J., Zhao, Q., Ishizawa, S., Fujimori, T., Nabeshima, Y., Mori, H., et al. (2009) · Journal of Neuroscience Research · doi:10.1002/jnr.22302 · Cited by 101

Bcl-2 Facilitates Recovery from DNA Damage after Oxidative Stress

Deng, G., Su, J. H., Ivins, K. J., Houten, B. V., & Cotman, C. W. (1999) · Experimental Neurology · doi:10.1006/exnr.1999.7145 · Cited by 99

Attenuation of oxidative neuronal cell death by coffee phenolic phytochemicals

Cho, E. S., Jang, Y. J., Hwang, M. K., Kang, N. J., Lee, K. W., & Lee, H. J. (2008) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2008.10.021 · Cited by 97

Generation of reactive oxygen species, release of l-glutamate and activation of caspases are required for oxygen-induced apoptosis of embryonic hippocampal neurons in culture

Ishikawa, Y., Satoh, T., Enokido, Y., Nishio, C., Ikeuchi, T., & Hatanaka, H. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01108-7 · Cited by 96

Herpes Simplex Virus Type 1 Vector-Mediated Expression of Nerve Growth Factor Protects Dorsal Root Ganglion Neurons from Peroxide Toxicity

Goins, W. F., Lee, K. A., Cavalcoli, J. D., O’Malley, M. E., DeKosky, S. T., Fink, D. J., & Glorioso, J. C. (1999) · Journal of Virology · doi:10.1128/jvi.73.1.519-532.1999 · Cited by 95

HERPES SIMPLEX VIRUS MEDIATED NERVE GROWTH FACTOR EXPRESSION IN BLADDER AND AFFERENT NEURONS: POTENTIAL TREATMENT FOR DIABETIC BLADDER DYSFUNCTION

Goins, W. F., Yoshimura, N., Phelan, M. W., Yokoyama, T., Fraser, M. O., Ozawa, H., Bennett, N., de Groat, W. C., Glorioso, J. C., & Chancellor, M. B. (2001) · The Journal of Urology · doi:10.1016/s0022-5347(05)66407-5 · Cited by 95

Protection of PC12 cells from hydrogen peroxide-induced cytotoxicity by salvianolic acid B, a new compound isolated from Radix Salviae miltiorrhizae

Liu, C.-S., Chen, N., & Zhang, J. (2006) · Phytomedicine · doi:10.1016/j.phymed.2006.11.002 · Cited by 94

Regulation of heme oxygenase-1 expression and MAPK pathways in response to kaempferol and rhamnocitrin in PC12 cells

Hong, J.-T., Yen, J.-H., Wang, L., Lo, Y., Chen, Z., & Wu, M. (2009) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2009.02.014 · Cited by 93

A selenium polysaccharide from Platycodon grandiflorum rescues PC12 cell death caused by H2O2 via inhibiting oxidative stress

Sheng, Y., Liu, G., Wang, M., Lv, Z., & Du, P. (2017) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.06.052 · Cited by 90

Antioxidant properties and PC12 cell protective effects of APS-1, a polysaccharide from Aloe vera var. chinensis

Wu, J. H., Chen, X., Shan, C., & Tan, R. X. (2005) · Life Sciences · doi:10.1016/j.lfs.2005.05.097 · Cited by 88

In vitro protective effects of Withania somnifera (L.) dunal root extract against hydrogen peroxide and β‐amyloid(1–42)‐induced cytotoxicity in differentiated PC12 cells

Kumar, S., Seal, C. J., Howes, M. R., Kite, G. C., & Okello, E. J. (2010) · Phytotherapy Research · doi:10.1002/ptr.3261 · Cited by 84

Purification of a Multipotent Antideath Activity from Bovine Liver and Its Identification as Arginase: Nitric Oxide-Independent Inhibition of Neuronal Apoptosis

Esch, F. S., Lin, K., Hills, A., Zaman, K., Baraban, J. M., Chatterjee, S., Rubin, L. L., Ash, D. E., & Ratan, R. R. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-11-04083.1998 · Cited by 83

Local control of mitochondrial membrane potential, permeability transition pore and reactive oxygen species by calcium and calmodulin in rat ventricular myocytes

Odagiri, K., Katoh, H., Kawashima, H., Tanaka, T. L., Ohtani, H., Saotome, M., Urushida, T., Satoh, H., & Hayashi, H. (2009) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2008.12.022 · Cited by 83

Modulation of hydrogen peroxide-induced DNA damage, MAPKs activation and cell death in PC12 by ergothioneine

COLOGNATO, R., LAURENZA, I., FONTANA, I., COPPEDE, F., SICILIANO, G., COECKE, S., ARUOMA, O., BENZI, L., & MIGLIORE, L. (2006) · Clinical Nutrition · doi:10.1016/j.clnu.2005.10.005 · Cited by 81

Synthesis and Characterization of Poly(ethylene glycol)−Glutathione Conjugate Self-Assembled Nanoparticles for Antioxidant Delivery

Williams, S. R., Lepene, B. S., Thatcher, C. D., & Long, T. E. (2008) · Biomacromolecules · doi:10.1021/bm801058j · Cited by 81

The neuroprotective effects of Lonicera japonica THUNB. against hydrogen peroxide-induced apoptosis via phosphorylation of MAPKs and PI3K/Akt in SH-SY5Y cells

Kwon, S., Hong, S., Kim, J., Jung, Y., Kim, S. Y., Kim, H., Lee, S., & Jang, C. (2011) · Food and Chemical Toxicology · doi:10.1016/j.fct.2011.01.008 · Cited by 77

Oxidative‐stress‐dependent up‐regulation of Bcl‐2 expression in the central nervous system of aged Fisher‐344 rats

Kaufmann, J. A., Bickford, P. C., & Taglialatela, G. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00118.x · Cited by 76

Effects of Methylmercury and Mercuric Chloride on Differentiation and Cell Viability in PC12 Cells

Parran, D. K. (2001) · Toxicological Sciences · doi:10.1093/toxsci/59.2.278 · Cited by 75

HYDROGEN PEROXIDE INDUCES APOPTOSIS IN HUMAN HEPATOMA CELLS AND ALTERS CELL REDOX STATUS

Li, J., Huang, C., Zheng, R., Cui, K., & Li, J. (2000) · Cell Biology International · doi:10.1006/cbir.1999.0438 · Cited by 74

Bcl-2 is a novel interacting partner for the 2-oxoglutarate carrier and a key regulator of mitochondrial glutathione

Wilkins, H., Marquardt, K., Lash, L. H., & Linseman, D. A. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.10.495 · Cited by 72

Bcl-XL translocation in renal tubular epithelial cells in vitro protects distal cells from oxidative stress

Cuttle, L., Zhang, X., Endre, Z. H., Winterford, C. M., & Gobe, G. C. (2001) · Kidney International · doi:10.1046/j.1523-1755.2001.0590051779.x · Cited by 68

Forsythiaside Protects Against Hydrogen Peroxide-Induced Oxidative Stress and Apoptosis in PC12 Cell

Huang, C., Lin, Y., Su, H., & Ye, D. (2014) · Neurochemical Research · doi:10.1007/s11064-014-1461-5 · Cited by 68

Neuroprotective effects of orientin on hydrogen peroxide-induced apoptosis in SH-SY5Y cells

LAW, B. N. T., Ling, A. P. K., Koh, R. Y., Chye, S. M., & Wong, Y. P. (2013) · Molecular Medicine Reports · doi:10.3892/mmr.2013.1878 · Cited by 66

Protective effect of lavender oil on scopolamine induced cognitive deficits in mice and H2O2 induced cytotoxicity in PC12 cells

Xu, P., Wang, K., Lu, C., Dong, L., Gao, L., Yan, M., Aibai, S., & Liu, X. (2016) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2016.08.030 · Cited by 64

Antioxidant and angiotensin I converting enzyme inhibitory activity of Bambusae caulis in Liquamen

Je, J., Park, P., Kim, E., & Ahn, C. (2008) · Food Chemistry · doi:10.1016/j.foodchem.2008.08.022 · Cited by 61

Cocoa procyanidins protect PC12 cells from hydrogen-peroxide-induced apoptosis by inhibiting activation of p38 MAPK and JNK

Cho, E. S., Lee, K. W., & Lee, H. J. (2008) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2007.12.012 · Cited by 61

Bis(7)-tacrine, a promising anti-Alzheimer's agent, reduces hydrogen peroxide-induced injury in rat pheochromocytoma cells: comparison with tacrine

Xiao, X. Q., Lee, N. T. K., Carlier, P. R., Pang, Y., & Han, Y. (2000) · Neuroscience Letters · doi:10.1016/s0304-3940(00)01357-4 · Cited by 59

Morroniside Prevents Peroxide-induced Apoptosis by Induction of Endogenous Glutathione in Human Neuroblastoma Cells

Wang, W., Huang, W., Li, L., Hou-xi, A., Sun, F., Liu, C., & An, Y. (2007) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-007-9168-7 · Cited by 59

Oxygen Toxicity Induces Apoptosis in Neuronal Cells

Satoh, T., Enokido, Y., Kubo, T., Yamada, M., & Hatanaka, H. (1998) · Cellular and Molecular Neurobiology · doi:10.1023/a:1020633919115 · Cited by 56

Effects of Banana, Orange, and Apple on Oxidative Stress‐Induced Neurotoxicity in PC12 Cells

Heo, H. J., Choi, S. J., Choi, S., Shin, D. ‐., Lee, J. M., & Lee, C. Y. (2008) · Journal of Food Science · doi:10.1111/j.1750-3841.2007.00632.x · Cited by 55

3′,4′,7-Trihydroxyflavone prevents apoptotic cell death in neuronal cells from hydrogen peroxide-induced oxidative stress

Kwon, S., Hong, S., Ma, S., Lee, S., & Jang, C. (2015) · Food and Chemical Toxicology · doi:10.1016/j.fct.2015.02.014 · Cited by 54

Pulsatile shear stress leads to DNA fragmentation in human SH‐SY5Y neuroblastoma cell line

Triyoso, D. H., & Good, T. A. (1999) · The Journal of Physiology · doi:10.1111/j.1469-7793.1999.355ac.x · Cited by 54

Functional dichotomy: glutathione and vitamin E in homeostasis relevant to primary open-angle glaucoma

Veach, J. E. (2004) · British Journal Of Nutrition · doi:10.1079/bjn20041113 · Cited by 53

Protection of PC12 cells from hydrogen peroxide-induced injury by EPS2, an exopolysaccharide from a marine filamentous fungus Keissleriella sp. YS4108

Sun, C., Shan, C., Gao, X., & Tan, R. X. (2004) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2004.08.011 · Cited by 52

α7 Nicotinic receptor-mediated protection against ethanol-induced oxidative stress and cytotoxicity in PC12 cells

Li, Y., King, M. A., & Meyer, E. M. (2000) · Brain Research · doi:10.1016/s0006-8993(99)02457-9 · Cited by 52

Comparison of antioxidant activities between salvianolic acid B and Ginkgo biloba extract (EGb 761)

Liu, C.-S., CHENG, Y., Hu, J., Zhang, W., Chen, N., & Zhang, J. (2006) · Acta Pharmacologica Sinica · doi:10.1111/j.1745-7254.2006.00378.x · Cited by 52

The Effect of Tetramethylpyrazine on Hydrogen Peroxide‐Induced Oxidative Damage in Human Umbilical Vein Endothelial Cells

Li, W., Liu, H., Li, X., Wu, J., Xu, G., Teng, Y., Ding, S., & Yu, C. (2009) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/j.1742-7843.2009.00470.x · Cited by 51

Reactive Oxygen Species Mediate Pyridostigmine-Induced Neuronal Apoptosis: Involvement of Muscarinic and NMDA Receptors

Li, L., Shou, Y., Borowitz, J. L., & Isom, G. E. (2001) · Toxicology and Applied Pharmacology · doi:10.1006/taap.2001.9283 · Cited by 49

Luteolin-induced protection of H2O2-induced apoptosis in PC12 cells and the associated pathway

LIN, P., Tian, X., YI, Y.-S., Wen-shi, J., ZHOU, Y.-J., & CHENG, W.-J. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.4400 · Cited by 48

Puerarin protects differentiated PC12 cells from H2O2‐induced apoptosis through the PI3K/Akt signalling pathway

Zhang, Q., Huang, W., Lv, X., & Yang, Y. (2011) · Cell Biology International · doi:10.1042/cbi20100900 · Cited by 45

Astragaloside IV attenuates the H2O2-induced apoptosis of neuronal cells by inhibiting α-synuclein expression via the p38 MAPK pathway

Liu, X., Zhang, J., Wang, S., Qiu, J., & Yu, C. (2017) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2017.3157 · Cited by 44

d-β-Hydroxybutyrate inhibited the apoptosis of PC12 cells induced by H2O2 via inhibiting oxidative stress

Cheng, B., Lu, H., Bai, B., & Chen, J. (2012) · Neurochemistry International · doi:10.1016/j.neuint.2012.09.011 · Cited by 42

Passage Variation of PC12 Cells Results in Inconsistent Susceptibility to Externally Induced Apoptosis

Kinarivala, N., Shah, K. K., Abbruscato, T. J., & Trippier, P. C. (2016) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.6b00208 · Cited by 41

Flavonoids from the leaves of Diospyros kaki reduce hydrogen peroxide-induced injury of NG108-15 cells

Bei, W., Peng, W., Ma, Y., & Xu, A. (2005) · Life Sciences · doi:10.1016/j.lfs.2004.09.031 · Cited by 40

Nerve growth factor protects against aluminum-mediated cell death

Ohyashiki, T., Satoh, E., Okada, M., Takadera, T., & Sahara, M. (2002) · Toxicology · doi:10.1016/s0300-483x(02)00139-7 · Cited by 40

In vivo and in vitro neuroprotective effects of maca polysaccharide

Zhou, Y. M., Zhu, L., Li, H., Xie, W., Liu, J., Zhang, Y., Li, Y., & Wang, C. (2022) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2701008 · Cited by 38

Zinc and Copper inhibit nerve growth factor-mediated protection from oxidative stress-induced apoptosis

Wang, W., Post, J. I., Dow, K. E., Shin, S. H., Riopelle, R. J., & Ross, G. M. (1999) · Neuroscience Letters · doi:10.1016/s0304-3940(98)00929-x · Cited by 38

Blockade of SOCE protects HT22 cells from hydrogen peroxide-induced apoptosis

Rao, W., Zhang, L., Su, N., Wang, K., Hui, H., Wang, L., Chen, T., Luo, P., Yang, Y., Liu, Z.-B., et al. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.10.054 · Cited by 40

The neuroprotective effects of ipriflavone against H2O2 and amyloid beta induced toxicity in human neuroblastoma SH-SY5Y cells

Xiao, Z., Huang, C., Wu, J., Sun, L., Hao, W., Leung, L. K., & Huang, J. (2013) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2013.09.023 · Cited by 37

Facet-Dependent Activity of CeO2 Nanozymes Regulate the Fate of Human Neural Progenitor Cell via Redox Homeostasis

Wang, Y., Tan, Z., Zhang, Z., Zhu, P., Tam, S. W., Zhang, Z., Jiang, X., Lin, K., Tian, L., Huang, Z., et al. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c09304 · Cited by 37

Towards resolving the enigma of the dichotomy of resveratrol: cis- and trans-resveratrol have opposite effects on TyrRS-regulated PARP1 activation

Jhanji, M., Rao, C. N., & Sajish, M. (2020) · GeroScience · doi:10.1007/s11357-020-00295-w · Cited by 37

Neuroprotective Effects of Protocatechuic Aldehyde against Neurotoxin-Induced Cellular and Animal Models of Parkinson’s Disease

Zhao, X. S., Zhai, S., An, M.-S., Wang, Y., Yang, Y.-F., Ge, H.-Q., Liu, J., & Pu, X. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078220 · Cited by 35

Oxidative Stress and the Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Pathway in Multiple Sclerosis: Focus on Certain Exogenous and Endogenous Nrf2 Activators and Therapeutic Plasma Exchange Modulation

Tonev, D. G., & Momchilova, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242417223 · Cited by 34

Efficient expression of tetracycline-responsive gene after transfection of dentate gyrus neurons in vitro

Jaworski, J., Figiel, I., Prószyński, T. J., & Kaczmarek, L. (2000) · Journal of Neuroscience Research · doi:10.1002/1097-4547(20000615)60:6 · Cited by 9

Rhodiola rosea Extract Protects Human Cortical Neurons against Glutamate and Hydrogen Peroxide‐induced Cell Death Through Reduction in the Accumulation of Intracellular Calcium

Palumbo, D. R., Occhiuto, F., Spadaro, F., & Circosta, C. (2011) · Phytotherapy Research · doi:10.1002/ptr.3662 · Cited by 34

VIP provides cellular protection through a specific splice variant of the PACAP receptor: A new neuroprotection target

Pilzer, I., & Gozes, I. (2006) · Peptides · doi:10.1016/j.peptides.2006.06.007 · Cited by 33

Gallic Acid Induces Neuronal Cell Death through Activation of c‐Jun N‐Terminal Kinase and Downregulation of Bcl‐2

Kang, M. K., Kang, N. J., Jang, Y. J., Lee, K. W., & Lee, H. J. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04728.x · Cited by 33

Transfection of C6 glioma cells with glia maturation factor upregulates brain-derived neurotrophic factor and nerve growth factor: trophic effects and protection against ethanol toxicity in cerebellar granule cells

Pantazis, N. J., Zaheer, A., Dai, D., Zaheer, S. A., Green, S. H., & Lim, R. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02194-6 · Cited by 32

Susceptibility of Differentiated Thyrocytes in Primary Culture to Undergo Apoptosis after Exposure to Hydrogen Peroxide: Relation with the Level of Expression of Apoptosis Regulatory Proteins, Bcl-2 and Bax

Riou, C., Tonoli, H., Bernier‐Valentin, F., Rabilloud, R., Fonlupt, P., & Rousset, B. (1999) · Endocrinology · doi:10.1210/en.140.5.1990 · Cited by 32

Neuronal cell protective and antioxidant effects of phenolics obtained from Zanthoxylum piperitum leaf using in vitro model system

Jeong, C., Kwak, J., Kim, J., Choi, G., Kim, D., & Heo, H. (2011) · Food Chemistry · doi:10.1016/j.foodchem.2010.09.022 · Cited by 28

Roles of Ras-Erk in Apoptosis of PC12 Cells Induced by Trophic Factor Withdrawal or Oxidative Stress

Jiang, H., Zhang, L., Koubi, D., Kuo, J., Groc, L., Rodríguez, A. I., Hunter, T. J., Tang, S., Lazarovici, P., Gautam, S. C., et al. (2005) · Journal of Molecular Neuroscience · doi:10.1385/jmn:25:2:133 · Cited by 31

Neuroprotective properties of Loranthus parasiticus aqueous fraction against oxidative stress-induced damage in NG108-15 cells

Wong, D. Z. H., Kadir, H. A., Lee, C. L., & Goh, B. H. (2012) · Journal of Natural Medicines · doi:10.1007/s11418-011-0622-y · Cited by 29

Cytoprotective effects of polyphenolics on H2O2-induced cell death in SH-SY5Y cells in relation to their antioxidant activities

Zhang, J., Melton, L. D., Adaim, A., & Skinner, M. A. (2008) · European Food Research and Technology · doi:10.1007/s00217-008-0915-x · Cited by 29

Protective Effect of Ursolic Acid fromCornus officinalison the Hydrogen Peroxide-Induced Damage of HEI-OC1 Auditory Cells

Yu, H., Hur, J.-M., Seo, S., Moon, H. K., Kim, H., Park, R., & You, Y. (2009) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x0900720x · Cited by 29

Effects of Antioxidant, Anti-Collagenase, Anti-Elastase, Anti-Tyrosinase of The Extract and Fraction From Turbinaria decurrens Bory.

Nurrochmad, A., Wirasti, W., Dirman, A., Lukitaningsih, E., Rahmawati, A., & Fakhrudin, N. (2018) · INDONESIAN JOURNAL OF PHARMACY · doi:10.14499/indonesianjpharm29iss4pp188 · Cited by 30

Protective effects of Orostachys japonicus A. Berger (Crassulaceae) on H2O2-induced apoptosis in GT1-1 mouse hypothalamic neuronal cell line

Yoon, Y., Kim, K.-S., Hong, S.-G., Kang, B.-J., Lee, M. Y., & Cho, D.-W. (2000) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(99)00107-5 · Cited by 28

Cytoprotection by Neutral Fraction of Tannat Red Wine against Oxidative Stress-Induced Cell Death

Echeverry, C., Blasina, F., Arredondo, F., Ferreira, M., Abin‐Carriquiry, J. A., Vásquez, L., Aspillaga, A. A., Diez, M. S., Leighton, F., & Dajas, F. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf040053q · Cited by 28

Glutathione Depletion Promotes Aluminum-Mediated Cell Death of PC12 Cells

Satoh, E., Okada, M., Takadera, T., & Ohyashiki, T. (2005) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.28.941 · Cited by 27

PAK2 activated by Cdc42 and caspase 3 mediates different cellular responses to oxidative stress-induced apoptosis

Huang, J. C., Huang, A., Poplawski, A. A., DiPino, F., Traugh, J. A., & Ling, J. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2020.118645 · Cited by 27

Brain-derived neurotrophic factor prevents superoxide anion-induced death of PC12h cells stably expressing TrkB receptor via modulation of reactive oxygen species

Tomoko, Y., Satoh, T., Ishikawa, Y., Nakatani, A., Yamada, M., Ikeuchi, T., & Hatanaka, H. (1999) · Neuroscience Research · doi:10.1016/s0168-0102(99)00062-0 · Cited by 27

Chamomile Confers Protection against Hydrogen Peroxide‐Induced Toxicity through Activation of Nrf2‐Mediated Defense Response

Bhaskaran, N., Srivastava, J. K., Shukla, S., & Gupta, S. (2012) · Phytotherapy Research · doi:10.1002/ptr.4701 · Cited by 26

Angiotensin II type 2 receptor-coupled nitric oxide production modulates free radical availability and voltage-gated Ca2+currents in NTS neurons

Wang, G., Coleman, C. G., Glass, M. J., Zhou, P., Yu, Q., Park, L., Anrather, J., Pickel, V. M., & Iadecola, C. (2012) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00571.2011 · Cited by 26

Scutellarin protects PC12 cells from oxidative stress-induced apoptosis

Hong, H., & Liu, G.-Q. (2006) · Journal of Asian Natural Products Research · doi:10.1080/10286020412331286470 · Cited by 25

EGb761 Protects Hydrogen Peroxide-induced Death of Spinal Cord Neurons through Inhibition of Intracellular ROS Production and Modulation of Apoptotic Regulating Genes

Jiang, X., Nie, B., Fu, S., Hu, J., Yin, L., Lin, L., Wang, X., Lu, P., & Xu, X. (2009) · Journal of Molecular Neuroscience · doi:10.1007/s12031-008-9140-0 · Cited by 25

Reactive oxygen species induce cell death via Akt signaling in rat osteoblast-like cell line ROS 17/2.8

Zhang, B., Xie, Q., Quan, Y., Pan, X., & Liao, D. (2013) · Toxicology and Industrial Health · doi:10.1177/0748233713491801 · Cited by 22

Protective effect of trihexyphenidyl on hydrogen peroxide-induced oxidative damage in PC12 cells

Ji, B., & Gao, Y. Z. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.03.089 · Cited by 22

Peroxide mediates ethanol-induced cytotoxicity in PC12 cells

Li, Y., Walker, D. W., & King, M. A. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00484-6 · Cited by 22

Up-Regulation of Nerve Growth Factor in Cholestatic Livers and Its Hepatoprotective Role against Oxidative Stress

Tsai, M., Lin, Y., Sun, C., Huang, S., Lee, P., & Kao, Y. H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0112113 · Cited by 21

Generation of Free Radicals during the Death of Saccharomyces cerevisiae Caused by Lipid Hydroperoxide

Aoshima, H., KADOYA, K., Taniguchi, H., Satoh, T., & Hatanaka, H. (1999) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.63.1025 · Cited by 21

The Fruits of Wampee Inhibit H2O2-Induced Apoptosis in PC12 Cells via the NF-κB Pathway and Regulation of Cellular Redox Status

Zeng, X., Zhou, X., Cui, L., Liu, D., Wu, K., Li, W., & Huang, R. (2014) · Molecules · doi:10.3390/molecules19067368 · Cited by 20

Engineering Modular, Oxygen‐Generating Microbeads for the In Situ Mitigation of Cellular Hypoxia

Accolla, R. P., Liang, J., Lansberry, T. R., Labrada, I. M., Loaisiga, M., Sardi, B. L., & Stabler, C. L. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202300239 · Cited by 19

Augmenter of liver regeneration plays a protective role against hydrogen peroxide-induced oxidative stress in renal proximal tubule cells

Xia, N., Yan, R., Liu, Q., Liao, X., Sun, H., Guo, H. M., & Zhang, L. (2015) · APOPTOSIS · doi:10.1007/s10495-015-1096-2 · Cited by 18

Antioxidant Effect of Melatonin in Human Retinal Neuron Cultures

Lee, M. C., Chung, Y.-T., Lee, J.-H., Jung, J.-J., Kim, H.-S., & Kim, S. U. (2001) · Experimental Neurology · doi:10.1006/exnr.2001.7793 · Cited by 18

Regulation of Reactive Oxygen Species by Nerve Growth Factor but not Bcl-2 as a Novel Mechanism of Protection of PC12 Cells from Superoxide Anion-Induced Death

Satoh, T., Yamagata, T., Ishikawa, Y., YAMADA, M., Uchiyama, Y., & Hatanaka, H. (1999) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a022374 · Cited by 26

The rescuing effect of nerve growth factor is the result of up-regulation of bcl-2 in hyperoxia-induced apoptosis of a subclone of pheochromocytoma cells, PC12h

Katoh, S., Mitsui, Y., Kitani, K., & Suzuki, T. (1997) · Neuroscience Letters · doi:10.1016/s0304-3940(97)00582-x · Cited by 25

Protection of oxidative preconditioning against apoptosis induced by H2O2 in PC12 cells: Mechanisms via MMP, ROS, and Bcl-2

Tang, X., Feng, J., Chen, J., Chen, P., Zhi, J., Cui, Y., Guo, R., & Yu, H. (2005) · Brain Research · doi:10.1016/j.brainres.2005.07.072 · Cited by 136

Nerve growth factor and forskolin prevent H2O2-induced apoptosis in PC12 cells by glutathione independent mechanism

Kamata, H., Tanaka, C., Yagisawa, H., & Hirata, H. (1996) · Neuroscience Letters · doi:10.1016/0304-3940(96)12806-8 · Cited by 63

Hydrogen Peroxide-Induced PC12 Cells Apoptosis and the Protective Effect of Paeoniflorin

Rong, S., Wu, D., Zuo-ping, Z., Yi, Y.-P., & Liu, G. (2006) · Zhōnghuá yàoxué zázhì · Cited by 1