Tetrapod phylogeny inferred from 18S and 28S ribosomal RNA sequences and a review of the evidence for amniote relationships.

S. Blair Hedges; Kirk D. Moberg; Linda R. Maxson

doi:10.1093/oxfordjournals.molbev.a040628

Cited by 198Evolution and Paleontology StudiesGenomics and Phylogenetic StudiesPaleontology and Evolutionary Biology

Tetrapod phylogeny inferred from 18S and 28S ribosomal RNA sequences and a review of the evidence for amniote relationships.

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S. Blair Hedges, Kirk D. Moberg, Linda R. Maxson·1990·Molecular Biology and Evolution

DOI 10.1093/oxfordjournals.molbev.a040628

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Abstract

The 18S ribosomal RNAs of 21 tetrapods were sequenced and aligned with five published tetrapod sequences. When the coelacanth was used as an outgroup, Lissamphibia (living amphibians) and Amniota (amniotes) were found to be statistically significant monophyletic groups. Although little resolution was obtained among the lissamphibian taxa, the amniote sequences support a sister-group relationship between birds and mammals. Portions of the 28S ribosomal RNA (rRNA) molecule in 11 tetrapods also were sequenced, although the phylogenetic results were inconclusive. In contrast to previous studies, deletion or down-weighting of base-paired sites were found to have little effect on phylogenetic relationships. Molecular evidence for amniote relationships is reviewed, showing that three genes (beta-hemoglobin, myoglobin, and 18S rRNA) unambiguously support a bird-mammal relationship, compared with one gene (histone H2B) that favors a bird-crocodilian clade. Separate analyses of four other genes (alpha-crystallin A, alpha-hemoglobin, insulin, and 28S rRNA) and a combined analysis of all sequence data are inconclusive, in that different groups are defined in different analyses and none are strongly supported. It is suggested that until sequences become available from a broader array of taxa, the molecular evidence is best evaluated at the level of individual genes, with emphasis placed on those studies with the greatest number of taxa and sites. When this is done, a bird-mammal relationship is most strongly supported. When regarded in combination with the morphological evidence for this association, it must be considered at least as plausible as a bird-crocodilian relationship.

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In vertebrate mt-rDNA as well as in nuclear rDNA, transversions tend to occur much less frequently than transitions.
“In vertebrate mt-rDNA (Hixson and Brown 1986) as well as in nuclear rDNA (Larson and Wilson 1989;Hedges et al. 1990), transversions tend to occur much less frequently than transitions.”
From Phylogeny of the Bovidae (Artiodactyla, Mammalia), based on mitochondrial ribosomal DNA sequences. (1992) · cites this paper as Hedges et al. 1990

CONFIDENCE LIMITS ON PHYLOGENIES: AN APPROACH USING THE BOOTSTRAP
Felsenstein, J. (1985) · Evolution · doi:10.1111/j.1558-5646.1985.tb00420.x · Cited by 44,735 · see citing works
Rapid determination of 16S ribosomal RNA sequences for phylogenetic analyses.
Lane, D. J., Pace, B., Olsen, G. J., Stahl, D. A., Sogin, M. L., & Pace, N. R. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.20.6955 · Cited by 3,057 · see citing works
PHYLOGENIES FROM MOLECULAR SEQUENCES: INFERENCE AND RELIABILITY
Felsenstein, J. (1988) · Annual Review of Genetics · doi:10.1146/annurev.ge.22.120188.002513 · Cited by 2,159 · see citing works
Vertebrate Paleontology and Evolution
Ostrom, J. H., & Carroll, R. L. (1988) · Palaios · doi:10.2307/3514548 · Cited by 1,669 · see citing works
AMNIOTE PHYLOGENY AND THE IMPORTANCE OF FOSSILS
Gauthier, J., Kluge, A. G., & Rowe, T. (1988) · Cladistics · doi:10.1111/j.1096-0031.1988.tb00514.x · Cited by 1,085 · see citing works
The mosaic genome of warm-blooded vertebrates
Bernardi, G., Olofsson, B., Filipski, J., Zerial, M., Salinas, J., Cuny, G., Meunier-Rotival, M., & Rodier, F. (1985) · Science · doi:10.1126/science.4001930 · Cited by 875 · see citing works
Basic Structure and Evolution of Vertebrates.
Weitzman, S. H., & Jarvik, E. (1981) · Systematic Zoology · doi:10.2307/2413058 · Cited by 826 · see citing works
The complete nucleotide sequence of mouse 28S rRNA gene. Implications for the process of size increase of the large subunit rRNA In higher eukaryotes
Hassouna, N., Mithot, B., & Bachellerie, J. (1984) · Nucleic Acids Research · doi:10.1093/nar/12.8.3563 · Cited by 617 · see citing works
Development of the Primary Antibody Repertoire
Alt, F. W., Blackwell, T. K., & Yancopoulos, G. D. (1987) · Science · doi:10.1126/science.3317825 · Cited by 604 · see citing works
The Mitochondrial Genome of Animals
Brown, W. M. (1985) · Springer eBooks · doi:10.1007/978-1-4684-4988-4_2 · Cited by 546 · see citing works
Hemoglobin: Structure, function, evolution, and pathology
Brunori, M. (1984) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(84)90080-x · Cited by 509 · see citing works
Hemoglobin : structure, function, evolution, and pathology
Dickerson, R. E., & Geis, I. (1983) · Andalas University Repository (Andalas University) · Cited by 451 · see citing works
The nucleotide sequence of a rat 18 S ribosomal ribonucleic acid gene and a proposal for the secondary structure of 18 S ribosomal ribonucleic acid.
Chan, Y., Gutell, R. R., Noller, H. F., & Wool, I. G. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)43645-3 · Cited by 408 · see citing works
Variation among human 28S ribosomal RNA genes.
Gonzalez, I. L., Gorski, J. L., Campen, T. J., Dorney, D. J., Erickson, J. M., Sylvester, J. E., & Schmickel, R. D. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.22.7666 · Cited by 288 · see citing works
The enzyme lactate dehydrogenase as a structural protein in avian and crocodilian lenses
Wistow, G. J., Mulders, J. W. M., & JONG, W. W. D. (1987) · Nature · doi:10.1038/326622a0 · Cited by 241 · see citing works
Paired sequence difference in ribosomal RNAs: evolutionary and phylogenetic implications.
(1988) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040480 · Cited by 234 · see citing works
Phylogeny of the major tetrapod groups: Morphological data and divergence dates
Benton, M. J. (1990) · Journal of Molecular Evolution · doi:10.1007/bf02101113 · Cited by 231 · see citing works
Molecules and Morphology in Evolution: Conflict or Compromise?
Hillis, D. M., & Patterson, C. (1988) · Copeia · doi:10.2307/1445904 · Cited by 177 · see citing works
A molecular view of primate phylogeny and important systematic and evolutionary questions.
Koop, B. F., Tagle, D. A., Goodman, M., & Slightom, J. L. (1989) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040574 · Cited by 127 · see citing works
Tetrapod classification
GARDINER, B. G. (1982) · Zoological Journal of the Linnean Society · doi:10.1111/j.1096-3642.1982.tb01148.x · Cited by 122 · see citing works
Amino Acid Sequence Evidence on the Phylogeny of Primates and Other Eutherians
Goodman, M., Romero-Herrera, A. E., Dene, H., Czelusniak, J., & Tashian, R. E. (1982) · Springer eBooks · doi:10.1007/978-1-4684-4283-0_4 · Cited by 93 · see citing works
Isolation and characterization of reptilian insulin, glucagon, and pancreatic polypeptide: Complete amino acid sequence of alligator (Alligator mississippiensis) insulin and pancreatic polypeptide
Lance, V. A., Hamilton, J. W., Rouse, J. B., KIMMEL, J. R., & POLLOCK, H. G. (1984) · General and Comparative Endocrinology · doi:10.1016/0016-6480(84)90135-7 · Cited by 89 · see citing works
Patterns of ribosomal RNA evolution in salamanders.
(1989) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040539 · Cited by 84 · see citing works
The amino acid sequence of alligator (Alligator mississippiensis) myoglobin phylogenetic implications
Dene, H., Sazy, J. A., Goodman, M., & Romero-Herrera, A. E. (1980) · Biochimica et Biophysica Acta (BBA) - Protein Structure · doi:10.1016/0005-2795(80)90081-1 · Cited by 29 · see citing works
alpha-Crystallin A sequences of Alligator mississippiensis and the lizard Tupinambis teguixin: molecular evolution and reptilian phylogeny.
JONG, W. W. D., Zweers, A., Versteeg, M., Dessauer, H. C., & Goodman, M. (1985) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040367 · Cited by 23 · see citing works
Classification et nomenclature supragénérique des Amphibiens Anoures
Dubois, A. (1983) · Bulletin mensuel de la Société linnéenne de Lyon · doi:10.3406/linly.1983.10607 · Cited by 23 · see citing works
Phylogenetic relationship of birds with crocodiles and mammals, as deduced from protein sequences.
Larhammar, D., & Milner, R. J. (1989) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040579 · Cited by 9 · see citing works

Flagged first, then by citations

2 of the 29 references couldn’t be matched to a known paper.

Sorted by citations

Ribosomal DNA: Molecular Evolution and Phylogenetic Inference
Hillis, D. M., & Dixon, M. T. (1991) · The Quarterly Review of Biology · doi:10.1086/417338 · Cited by 2,552 · see citing works
A Simple Method for Estimating and Testing Minimum-Evolution Trees
Rzhetsky, A., & Nei, M. (1992) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040771 · Cited by 1,484 · see citing works
Compilation of small ribosomal subunit RNA sequences
Rijk, P. D., Neefs, J., de Peer, Y. V., & Wächter, R. D. (1992) · Nucleic Acids Research · doi:10.1093/nar/20.suppl.2075 · Cited by 963 · see citing works
Recovering evolutionary trees under a more realistic model of sequence evolution.
Lockhart, P. J., Steel, M., Hendy, M. D., & Penny, D. (1994) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040136 · Cited by 961 · see citing works
Combining data in phylogenetic analysis
Huelsenbeck, J. P., Bull, J. J., & Cunningham, C. (1996) · Trends in Ecology & Evolution · doi:10.1016/0169-5347(96)10006-9 · Cited by 871 · see citing works
Taxonomic congruence versus total evidence, and amniote phylogeny inferred from fossils, molecules, and morphology.
Eernisse, D. J., & Kluge, A. G. (1993) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040071 · Cited by 424 · see citing works
The draft genomes of soft-shell turtle and green sea turtle yield insights into the development and evolution of the turtle-specific body plan
Wang, Z., Pascual‐Anaya, J., Zadissa, A., Li, W., Niimura, Y., Huang, Z., Li, C., White, S., Xiong, Z., Fang, D., et al. (2013) · Nature Genetics · doi:10.1038/ng.2615 · Cited by 422 · see citing works
Dating the evolutionary radiations of the true fungi
Berbee, M. L., & Taylor, J. W. (1993) · Canadian Journal of Botany · doi:10.1139/b93-131 · Cited by 390 · see citing works
More than 1000 ultraconserved elements provide evidence that turtles are the sister group of archosaurs
Crawford, N. G., Faircloth, B. C., McCormack, J. E., Brumfield, R. T., Winker, K., & Glenn, T. C. (2012) · Biology Letters · doi:10.1098/rsbl.2012.0331 · Cited by 355 · see citing works
A Molecular Phylogeny of Reptiles
Hedges, S. B., & Poling, L. L. (1999) · Science · doi:10.1126/science.283.5404.998 · Cited by 344 · see citing works
Self-citation
Molecular evidence for the origin of birds.
Hedges, S. B. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.7.2621 · Cited by 292 · see citing works
Self-citation
RNA secondary structure: physical and computational aspects
Higgs, P. G. (2000) · Quarterly Reviews of Biophysics · doi:10.1017/s0033583500003620 · Cited by 283 · see citing works
PCR Primers and Amplification Methods for 12S Ribosomal DNA, the Control Region, Cytochrome Oxidase I, and Cytochromebin Bufonids and Other Frogs, and an Overview of PCR Primers which Have Amplified DNA in Amphibians Successfully
Goebel, A. M., Donnelly, J. M., & Atz, M. E. (1999) · Molecular Phylogenetics and Evolution · doi:10.1006/mpev.1998.0538 · Cited by 259 · see citing works
Relative efficiencies of the maximum-likelihood, neighbor-joining, and maximum-parsimony methods when substitution rate varies with site.
Tateno, Y., Takezaki, N., & Nei, M. (1994) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040108 · Cited by 252 · see citing works
Rooting molecular trees: problems and strategies
Smith, A. B. (1994) · Biological Journal of the Linnean Society · doi:10.1111/j.1095-8312.1994.tb00962.x · Cited by 238 · see citing works
Testability and the Refutation and Corroboration of Cladistic Hypotheses
Kluge, A. G. (1997) · Cladistics · doi:10.1111/j.1096-0031.1997.tb00242.x · Cited by 238 · see citing works
Complete mitochondrial genome suggests diapsid affinities of turtles
Zardoya, R., & Meyer, A. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.24.14226 · Cited by 221 · see citing works
Complete mitochondrial DNA sequences of the green turtle and blue- tailed mole skink: statistical evidence for archosaurian affinity of turtles
Kumazawa, Y., & Nishida, M. (1999) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a026163 · Cited by 221 · see citing works
Oxidative shielding and the cost of reproduction
Blount, J. D., Vitikainen, E., Stott, I., & Cant, M. A. (2015) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12179 · Cited by 206 · see citing works
Fossils, Molecules, Divergence Times, and the Origin of Lissamphibians
Marjanović, D., & Laurin, M. (2007) · Systematic Biology · doi:10.1080/10635150701397635 · Cited by 204 · see citing works
Phylogenetic relationships of amphibian families inferred from DNA sequences of mitochondrial 12S and 16S ribosomal RNA genes.
Hay, J. M., Ruvinsky, I., Hedges, S. B., & Maxson, L. R. (1995) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040270 · Cited by 204 · see citing works
Self-citation
Recent Advances in the (Molecular) Phylogeny of Vertebrates
Meyer, A., & Zardoya, R. (2003) · Annual Review of Ecology Evolution and Systematics · doi:10.1146/annurev.ecolsys.34.011802.132351 · Cited by 201 · see citing works
Molecular Evidence for the Early History of Living Amphibians
Feller, A. E., & Hedges, S. B. (1998) · Molecular Phylogenetics and Evolution · doi:10.1006/mpev.1998.0500 · Cited by 200 · see citing works
Self-citation
Model Selection and Parameter Inference in Phylogenetics Using Nested Sampling
Maturana‐Russel, P., Brewer, B. J., Klaere, S., & Bouckaert, R. (2018) · Systematic Biology · doi:10.1093/sysbio/syy050 · Cited by 198 · see citing works
A Likelihood Ratio Test to Detect Conflicting Phylogenetic Signal
Huelsenbeck, J. P., & Bull, J. J. (1996) · Systematic Biology · doi:10.1093/sysbio/45.1.92 · Cited by 197 · see citing works
Congruence Between Molecular and Morphological Phylogenies
Patterson, C., Williams, D. M., & Humphries, C. (1993) · Annual Review of Ecology and Systematics · doi:10.1146/annurev.es.24.110193.001101 · Cited by 191 · see citing works
Why we have (only) five fingers per hand: Hox genes and the evolution of paired limbs
Tabin, C. J. (1992) · Development · doi:10.1242/dev.116.2.289 · Cited by 185 · see citing works
Estimating phylogenetic trees from genome‐scale data
Liu, L., Xi, Z., Wu, S., Davis, C. “., & Edwards, S. V. (2015) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12747 · Cited by 182 · see citing works
Mitogenomic Perspectives on the Origin and Phylogeny of Living Amphibians
Zhang, P., Zhou, H., Chen, Y., Liu, Y., & Qu, L. (2005) · Systematic Biology · doi:10.1080/10635150590945278 · Cited by 182 · see citing works
The complete mitochondrial genome of Alligator mississippiensis and the separation between recent archosauria (birds and crocodiles)
Janke, A., & Árnason, Ú. (1997) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a025736 · Cited by 168 · see citing works
BEST‐FIT MAXIMUM‐LIKELIHOOD MODELS FOR PHYLOGENETIC INFERENCE: EMPIRICAL TESTS WITH KNOWN PHYLOGENIES
Cunningham, C., Zhu, H., & Hillis, D. M. (1998) · Evolution · doi:10.1111/j.1558-5646.1998.tb01827.x · Cited by 162 · see citing works
Phylogeny and Comparative Substitution Rates of Frogs Inferred from Sequences of Three Nuclear Genes
Hoegg, S. (2004) · Molecular Biology and Evolution · doi:10.1093/molbev/msh081 · Cited by 147 · see citing works
Phylogeny of Greya (Lepidoptera: Prodoxidae), based on nucleotide sequence variation in mitochondrial cytochrome oxidase I and II: congruence with morphological data.
Brown, J. M., Pellmyr, O., Thompson, J. N., & Harrison, R. G. (1994) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040087 · Cited by 146 · see citing works
Phylogenetic position of phylum Nemertini, inferred from 18S rRNA sequences: molecular data as a test of morphological character homology.
Turbeville, J. M., Field, K. G., & Raff, R. A. (1992) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040716 · Cited by 144 · see citing works
Sexing chick embryos: A rapid and simple protocol
Clinton, M., Haines, L., Belloir, B., & McBride, D. (2001) · British Poultry Science · doi:10.1080/713655025 · Cited by 143 · see citing works
Variations in mitochondrial tRNA gene organization of reptiles as phylogenetic markers.
Kumazawa, Y., & Nishida, M. (1995) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040254 · Cited by 136 · see citing works
Extreme differences in rates of molecular evolution of foraminifera revealed by comparison of ribosomal DNA sequences and the fossil record
Pawlowski, J. W., Bolívar, I., Fahrni, J. F., de Vargas, C., Gouy, M., & Zaninetti, L. (1997) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a025786 · Cited by 133 · see citing works
Caecilian Phylogeny and Biogeography Inferred from Mitochondrial DNA Sequences of the 12S rRNA and 16S rRNA Genes (Amphibia: Gymnophiona)
Hedges, S. B., Nussbaum, R. A., & Maxson, L. R. (1993) · Herpetological Monographs · doi:10.2307/1466952 · Cited by 129 · see citing works
Self-citation
The isochore organization of the human genome and its evolutionary history — a review
Bernardi, G. (1993) · Gene · doi:10.1016/0378-1119(93)90049-9 · Cited by 128 · see citing works
Molecular Phylogenetic Study of the Ranunculaceae: Utility of the Nuclear 26S Ribosomal DNA in Inferring Intrafamilial Relationships
Ro, K., Keener, C. S., & McPheron, B. A. (1997) · Molecular Phylogenetics and Evolution · doi:10.1006/mpev.1997.0413 · Cited by 123 · see citing works
A phylogeny for side-necked turtles (Chelonia: Pleurodira) based on mitochondrial and nuclear gene sequence variation
Georges, A., Birrell, J., Saint, K. M., McCord, W. P., & Donnellan, S. C. (1999) · Biological Journal of the Linnean Society · doi:10.1006/bijl.1998.0300 · Cited by 121 · see citing works
The evolutionary position of turtles revised
Zardoya, R., & Meyer, A. (2001) · Die Naturwissenschaften · doi:10.1007/s001140100228 · Cited by 121 · see citing works
Reconstructing evolution from eukaryotic small-ribosomal-subunit RNA sequences: Calibration of the molecular clock
de Peer, Y. V., Neefs, J., Rijk, P. D., & Wächter, R. D. (1993) · Journal of Molecular Evolution · doi:10.1007/bf02407359 · Cited by 120 · see citing works
The mitochondrial genomes of the iguana (Iguana iguana) and the caiman (Caiman crocodylus): implications for amniote phylogeny
Janke, A., Erpenbeck, D., Nilsson, M., & Árnason, Ú. (2001) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2000.1402 · Cited by 119 · see citing works
On the origin of and phylogenetic relationships among living amphibians
Zardoya, R., & Meyer, A. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.111455498 · Cited by 117 · see citing works
18S ribosomal RNA gene phylogeny for some Rhabditidae related to Caenorhabditis.
Fitch, D. H. A., Bugaj‐Gaweda, B., & Emmons, S. W. (1995) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040207 · Cited by 117 · see citing works
Evolution of the WANCY region in amniote mitochondrial DNA.
Seutin, G., Lang, B. F., Mindell, D. P., & Morais, R. (1994) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040116 · Cited by 113 · see citing works
Ribosomal RNA genes and deuterostome phylogeny revisited: More cyclostomes, elasmobranchs, reptiles, and a brittle star
Mallatt, J. M., & Winchell, C. J. (2006) · Molecular Phylogenetics and Evolution · doi:10.1016/j.ympev.2006.11.023 · Cited by 110 · see citing works
Mitochondrial phylogeny of the endemic mouthbrooding lineages of cichlid fishes from Lake Tanganyika in eastern Africa.
Sturmbauer, C., & Meyer, A. (1993) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040042 · Cited by 108 · see citing works
CONVERGENT EVOLUTION IN INVERTEBRATES
Moore, J., & Willmer, P. G. (1997) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1017/s0006323196004926 · Cited by 106 · see citing works
Molecular divergence and phylogeny: rates and patterns of cytochrome b evolution in cranes
Krajewski, C., & King, D. G. (1996) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a025558 · Cited by 105 · see citing works
Molecular studies suggest that cartilaginous fishes have a terminal position in the piscine tree
Rasmussen, A.-S., & Árnason, Ú. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.5.2177 · Cited by 103 · see citing works
Phylogenetic relationships and biogeography of xantusiid lizards, inferred from mitochondrial DNA sequences.
Hedges, S. B., Bezy, R. L., & Maxson, L. R. (1991) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040689 · Cited by 102 · see citing works
Self-citation
Molecules, fossils, and the origin of tetrapods
Meyer, A., & Dolven, S. (1992) · Journal of Molecular Evolution · doi:10.1007/bf00183221 · Cited by 98 · see citing works
A Molecular Perspective on Lissamphibian Phylogeny
Hedges, S. B., & Maxson, L. R. (1993) · Herpetological Monographs · doi:10.2307/1466949 · Cited by 98 · see citing works
Self-citation
18S Ribosomal RNA and Tetrapod Phylogeny
Xia, X., Xie, Z., & Kjer, K. M. (2003) · Systematic Biology · doi:10.1080/10635150390196948 · Cited by 97 · see citing works
Quantifying MCMC Exploration of Phylogenetic Tree Space
Whidden, C., & Matsen, F. A., IV (2015) · Systematic Biology · doi:10.1093/sysbio/syv006 · Cited by 96 · see citing works
The tetrapod limb: A hypothesis on its origin
Wagner, G. P., & Chiu, C.-H. (2001) · Journal of Experimental Zoology · doi:10.1002/jez.1100 · Cited by 93 · see citing works
Morphology's Role in Phylogeny Reconstruction: Perspectives from Paleontology
Smith, N. D., & Turner, A. H. (2005) · Systematic Biology · doi:10.1080/10635150590906000 · Cited by 89 · see citing works
A Paedomorphic Parasite Associated with a Neotenic Amphibian Host: Phylogenetic Evidence Suggests a Revised Systematic Position for Sphyranuridae within Anuran and Turtle Polystomatoineans
Sinnappah-Kang, N. D., Lim, L.-H. S., Rohde, K., TINSLEY, R. C., Combes, C., & Verneau, O. (2001) · Molecular Phylogenetics and Evolution · doi:10.1006/mpev.2000.0877 · Cited by 89 · see citing works
The Different Meanings of a Tarsioid — Anthropoid Clade and a New Model of Anthropoid Origin
Rasmussen, D. T. (1994) · Springer eBooks · doi:10.1007/978-1-4757-9197-6_12 · Cited by 84 · see citing works
Nearly complete rRNA genes assembled from across the metazoan animals: Effects of more taxa, a structure-based alignment, and paired-sites evolutionary models on phylogeny reconstruction
Mallatt, J. M., Craig, C. W., & Yoder, M. J. (2009) · Molecular Phylogenetics and Evolution · doi:10.1016/j.ympev.2009.09.028 · Cited by 84 · see citing works
Warm-blooded isochore structure in Nile crocodile and turtle
Hughes, S., Zelus, D., & Mouchiroud, D. (1999) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a026064 · Cited by 84 · see citing works
Comparative variation of morphological and molecular evolution through geologic time: 28 S ribosomal RNA versus morphology in echinoids
Smith, A. B., Lafay, B., & Christen, R. (1992) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.1992.0155 · Cited by 82 · see citing works
Amphibian teeth: current knowledge, unanswered questions, and some directions for future research
Davit‐Béal, T., Chisaka, H., Delgado, S., & Sire, J. (2007) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/j.1469-185x.2006.00003.x · Cited by 81 · see citing works
Molecular Evolution of the Mitochondrial Genome
Quinn, T. W. (1997) · Elsevier eBooks · doi:10.1016/b978-012498315-1/50002-9 · Cited by 81 · see citing works
Phylogeny of the Bovidae (Artiodactyla, Mammalia), based on mitochondrial ribosomal DNA sequences.
(1992) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040734 · Cited by 80 · see citing works
The complete mitochondrial genome of the Chinese giant salamander, Andrias davidianus (Amphibia: Caudata)
Zhang, P., Chen, Y., Liu, Y., Zhou, H., & Qu, L. (2003) · Gene · doi:10.1016/s0378-1119(03)00560-2 · Cited by 79 · see citing works
K-mer natural vector and its application to the phylogenetic analysis of genetic sequences
Wen, J., Chan, R. H.-F., Yau, S.-C., He, R. L., & Yau, S. S. ‐. (2014) · Gene · doi:10.1016/j.gene.2014.05.043 · Cited by 79 · see citing works
Empirical Problems of the Hierarchical Likelihood Ratio Test for Model Selection
Pol, D. (2004) · Systematic Biology · doi:10.1080/10635150490888868 · Cited by 76 · see citing works
Parsimony Analysis of Total Evidence from Extinct and Extant Taxa and the Cetacean-Artiodactyl Question (Mammalia, Ungulata)
O’Leary, M. A. (1999) · Cladistics · doi:10.1006/clad.1999.0112 · Cited by 76 · see citing works
Isolation of chicken primordial germ cells using fluorescence-activated cell sorting
Mozdziak, P. E., Angerman‐Stewart, J., Rushton, B. C., Pardue, S. L., & Petitte, J. N. (2005) · Poultry Science · doi:10.1093/ps/84.4.594 · Cited by 75 · see citing works
Terminal differentiation of normal chicken erythroid progenitors: shortening of G1 correlates with loss of D-cyclin/cdk4 expression and altered cell size control.
Dolznig, H., Bartůněk, P., Nasmyth, K., Müllner, E. W., & Beug, H. (1995) · PubMed · Cited by 73 · see citing works
The platypus is not a rodent: DNA hybridization, amniote phylogeny and the palimpsest theory
Kirsch, J. A. W., & Mayer, G. C. (1998) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.1998.0278 · Cited by 67 · see citing works
Molecular biogeography: using the Corsica‐Sardinia microplate disjunction to calibrate mitochondrial rDNA evolutionary rates in mountain newts (Euproctus)
Caccone, A., Milinkovitch, M. C., Sbordoni, V., & Powell, J. R. (1994) · Journal of Evolutionary Biology · doi:10.1046/j.1420-9101.1994.7020227.x · Cited by 67 · see citing works
An overview of the secondary structure of the V4 region of eukaryotic small-subunit ribosomal RNA
Nickrent, D. L., & Sargent, M. (1991) · Nucleic Acids Research · doi:10.1093/nar/19.2.227 · Cited by 66 · see citing works
The complete mitochondrial genome of a relic salamander, Ranodon sibiricus (Amphibia: Caudata) and implications for amphibian phylogeny
Zhang, P., Chen, Y.-Q., Zhou, H., Wang, X.-L., & Qu, L. (2003) · Molecular Phylogenetics and Evolution · doi:10.1016/s1055-7903(03)00059-9 · Cited by 61 · see citing works
Molecular evolution of the mitochondrial 12S rRNA in Ungulata (mammalia)
Douzery, E., & Catzeflis, F. M. (1995) · Journal of Molecular Evolution · doi:10.1007/bf00175821 · Cited by 61 · see citing works
Monophyly of the order Rodentia inferred from mitochondrial DNA sequences of the genes for 12S rRNA, 16S rRNA, and tRNA-valine.
Frye, M. S., & Hedges, S. B. (1995) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040186 · Cited by 61 · see citing works
Self-citation
Molecular evolution of ependymin and the phylogenetic resolution of early divergences among euteleost fishes
Ortı́, G., & Meyer, A. (1996) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a025616 · Cited by 60 · see citing works
Evolution of the Neuropeptide Y Family of Peptides
Larhammar, D., Söderberg, C., & Blomquist, A. G. (1993) · Humana Press eBooks · doi:10.1007/978-1-59259-465-8_1 · Cited by 60 · see citing works
Molecular Phylogenetics at the Felsenstein Zone: Approaching the Strepsiptera Problem Using 5.8S and 28S rDNA Sequences
Hwang, U. W., Kim, W. D., Tautz, D., & Friedrich, M. (1998) · Molecular Phylogenetics and Evolution · doi:10.1006/mpev.1998.0518 · Cited by 59 · see citing works
Cladistic analyses of behavioural variation in wild Pan troglodytes: exploring the chimpanzee culture hypothesis
Lycett, S. J., Mark Collard, A., & McGrew, W. C. (2009) · Journal of Human Evolution · doi:10.1016/j.jhevol.2009.05.015 · Cited by 58 · see citing works
W(h)ither Fossils? Studying Morphological Character Evolution in the Age of Molecular Sequences1
Hermsen, E. J., & Hendricks, J. R. (2008) · Annals of the Missouri Botanical Garden · doi:10.3417/2006206 · Cited by 57 · see citing works
A view of early vertebrate evolution inferred from the phylogeny of polystome parasites (Monogenea: Polystomatidae)
Verneau, O., Bentz, S., Sinnappah-Kang, N. D., Preez, L. D., Whittington, I. D., & Combes, C. (2002) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2001.1899 · Cited by 57 · see citing works
Preservation of biomolecules in cancellous bone ofTyrannosaurus rex
Schweitzer, M. H., Johnson, C. I., Zocco, T. G., Horner, J. R., & Starkey, J. R. (1997) · Journal of Vertebrate Paleontology · doi:10.1080/02724634.1997.10010979 · Cited by 54 · see citing works
The Mammalian Crx Genes Are Highly Divergent Representatives of the Otx5 Gene Family, a Gnathostome Orthology Class of Orthodenticle-Related Homeogenes Involved in the Differentiation of Retinal Photoreceptors and Circadian Entrainment
Plouhinec, J.-L. (2003) · Molecular Biology and Evolution · doi:10.1093/molbev/msg085 · Cited by 53 · see citing works
From Easy to Hopeless—Predicting the Difficulty of Phylogenetic Analyses
Haag, J., Höhler, D., Bettisworth, B., & Stamatakis, A. (2022) · Molecular Biology and Evolution · doi:10.1093/molbev/msac254 · Cited by 52 · see citing works
Complete nucleotide sequence and gene rearrangement of the mitochondrial genome of the bell-ring frog, Buergeria buergeri (family Rhacophoridae)
Sano, N., Kurabayashi, A., Fujii, T., Yonekawa, H., & Sumida, M. (2004) · Genes & Genetic Systems · doi:10.1266/ggs.79.151 · Cited by 52 · see citing works
Assessing horizontal transfer of nifHDK genes in eubacteria: nucleotide sequence of nifK from Frankia strain HFPCcI3.
Hirsch, A. M., McKhann, H. I., Reddy, A., Liao, J., Fang, Y., & Marshall, C. R. (1995) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a040184 · Cited by 52 · see citing works
Molecular Evidence for a Clade of Turtles
Mannen, H., & Li, S. S. ‐. (1999) · Molecular Phylogenetics and Evolution · doi:10.1006/mpev.1999.0640 · Cited by 52 · see citing works
EVOLUTIONARY ORIGIN OF THE CYCLORRHAPHA (DIPTERA): TEST OF ALTERNATIVE MORPHOLOGICAL HYPOTHESES
Wiegmann, B. M., Mitter, C. W., & Thompson, F. C. (1993) · Cladistics · doi:10.1006/clad.1993.1002 · Cited by 51 · see citing works
Support, Ribosomal Sequences and the Phylogeny Of The Eukaryotes
Lipscomb, D., Farris, J. S., Källersjö, M., & Tehler, A. (1998) · Cladistics · doi:10.1111/j.1096-0031.1998.tb00341.x · Cited by 50 · see citing works
Origin, evolution, and phylogeography of recent epidemic CHIKV strains
Presti, A. L., Ciccozzi, M., Cella, E., Lai, A., Simonetti, F. R., Galli, M., Zehender, G., & Rezza, G. (2012) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2011.12.015 · Cited by 49 · see citing works
Phylogenetic Analysis of Reptilian Hemoglobins: Trees, Rates, and Divergences
Gorr, T. A., Mable, B. K., & Kleinschmidt, T. (1998) · Journal of Molecular Evolution · doi:10.1007/pl00006404 · Cited by 49 · see citing works
Turtles as diapsid reptiles
Rieppel, O. C. (2000) · Zoologica Scripta · doi:10.1046/j.1463-6409.2000.00039.x · Cited by 48 · see citing works
Three-dimensional Structural Interactions of Insulin and Its Receptor
Yip, C. C., & Ottensmeyer, P. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.r300021200 · Cited by 48 · see citing works
Tetrapod Phylogeny, Amphibian Origins, and the Definition of the Name Tetrapoda
Laurin, M. (2002) · Systematic Biology · doi:10.1080/10635150252899815 · Cited by 47 · see citing works
GPS it: An automated method for evolutionary analysis of nonculturable ciliated microeukaryotes
Chen, X., Wang, Y., Sheng, Y., Warren, A., & Gao, S. (2018) · Molecular Ecology Resources · doi:10.1111/1755-0998.12750 · Cited by 45 · see citing works
Inhibition of Sonic hedgehog signaling leads to posterior digit loss in Ambystoma mexicanum: Parallels to natural digit reduction in urodeles
Stopper, G. F., & Wagner, G. P. (2006) · Developmental Dynamics · doi:10.1002/dvdy.21025 · Cited by 45 · see citing works

Authors: Hedges, S. B., Moberg, K. D., & Maxson, L. R.
Affiliations: Pennsylvania State University (US)
ORCID: S. Blair Hedges
Venue: Molecular Biology and Evolution
Publisher: Oxford University Press (OUP)
Published: 1990-11
Volume: 7
Issue: 6
Pages: 607-33
ISSN: 0737-4038 (ISSN-L)
1537-1719
DOI: 10.1093/oxfordjournals.molbev.a040628
OpenAlex: W2291705348
Cited by: 198
References: 29
Citations by year: 2025: 1 · 2023: 3 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 3 · 2018: 2 · 2017: 3 · 2016: 1 · 2015: 3 · 2014: 6 · 2013: 2 · 2012: 7
FWCI: 20.18
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Molecular Biology and Evolution (publishedVersion)
PubMed (publishedVersion)
Funders: National Science Foundation
University of Illinois at Urbana-Champaign
Topics: Physical Sciences › Earth and Planetary Sciences › Paleontology › Evolution and Paleontology Studies
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
Physical Sciences › Earth and Planetary Sciences › Paleontology › Paleontology and Evolutionary Biology
Keywords: tetrapod phylogeny, 18S rRNA, 28S rRNA, Lissamphibia, amniotes, myoglobin, histone H2B, insulin, monophyly
MeSH terms: Animals, Base Sequence, Biological Evolution, Humans, Molecular Sequence Data, Phylogeny, RNA, Ribosomal, 18S, RNA, Ribosomal, 28S

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Tetrapod phylogeny inferred from 18S and 28S ribosomal RNA sequences and a review of the evidence for amniote relationships.

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