Sexuality and Schizophrenia: A Review

Kelly, D. L.; Conley, R. R.

doi:10.1093/oxfordjournals.schbul.a007130

Cited by 164Schizophrenia research and treatmentSexual function and dysfunction studiesMental Health and Psychiatry

Sexuality and Schizophrenia: A Review

Kelly, D. L., Conley, R. R.·2004·Schizophrenia Bulletin

DOI 10.1093/oxfordjournals.schbul.a007130

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Abstract

Sexual functioning has received little attention as an important aspect of patient care for those suffering from severe mental disorders such as schizophrenia. Yet, it has been implicated as one of the major factors contributing to noncompliance with antipsychotic medications and is documented by people with schizophrenia to be one of the areas of treatment with the most unmet needs. A stronger focus on sexuality and preventing sexual dysfunction in schizophrenia would likely be a major benefit for improving treatment. This review will describe possible mechanisms for sexual dysfunction, describe sexual disturbances that have been documented in the literature of people who have schizophrenia, and summarize and discuss assessment measures available. Moreover, a focus on second-generation antipsychotics (SGA) and their association with sexual functioning is described. Each SGA (clozapine, risperidone, olanzapine, quetiapine, ziprasidone, and aripiprazole) will be described for its prolactin effects, documented sexual disturbances associated with use, and product labeling regarding sexual function. Treatment options and psychosocial issues pertaining to sexuality also are presented.

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Sexual dysfunction in SMI patients has received little attention from clinicians.
“Sexual dysfunction in SMI patients has received little attention from clinicians (512,513).”
From Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care (2011) · cites this paper as [512]
Sexual dysfunction in schizophrenia is estimated to be more frequent compared to normal controls and to affect 30-80% of women and 45-80% of men.
“Although there are relatively few systematic investigations concerning sexual disorders in schizophrenia (514), sexual dysfunction in schizophrenia is, compared to normal controls, estimated to be more frequent (515-519) and to affect 30-80% of women and 45-80% of men (512,515, 520-523).”
From Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care (2011) · cites this paper as [512]

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Authors: Kelly, D. L., & Conley, R. R.
Affiliations: University of Maryland, Baltimore (US)
Venue: Schizophrenia Bulletin
Publisher: Oxford University Press (OUP)
Published: 2004-01-01
Volume: 30
Issue: 4
Pages: 767-779
ISSN: 0586-7614 (ISSN-L)
1745-1701
DOI: 10.1093/oxfordjournals.schbul.a007130
OpenAlex: W1978827798
Cited by: 164
References: 128
Citations by year: 2026: 1 · 2025: 4 · 2024: 6 · 2023: 9 · 2022: 7 · 2021: 2 · 2020: 9 · 2019: 7 · 2018: 13 · 2017: 8 · 2016: 6 · 2015: 4 · 2014: 9 · 2013: 18 · 2012: 10
FWCI: 2.28
Type: journal article
Language: en
Open access: closed
Locations: Schizophrenia Bulletin (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Keywords: schizophrenia, sexuality
MeSH terms: Amenorrhea, Female, Humans, Male, Prolactin, Schizophrenia, Schizophrenic Psychology, Sexual Behavior, Antipsychotic Agents

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Sexuality and Schizophrenia: A Review

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